Table Of Content

Essentials of Human Physiology for Principles, Strategies, and Systems Pharmacy CRC PRESS PHARMACY EDUCATION SERIES Pharmacoethics: A Problem-Based Approach David A. Gettman and Dean Arneson Pharmaceutical Care: Insights from Community Pharmacists William N. Tindall and Marsha K. Millonig Essentials of Law and Ethics for Pharmacy Technicians Kenneth M. Strandberg Essentials of Pharmacy Law Douglas J. Pisano Essentials of Pathophysiology for Pharmacy Martin M. Zdanowicz Pharmacy: What It Is and How It Works William N. Kelly Pharmacokinetic Principles of Dosing Adjustments: Understanding the Basics Ronald Schoenwald Strauss’s Federal Drug Laws and Examination Review, Fifth Edition Steven Strauss Pharmaceutical and Clinical Calculations, Second Edition Mansoor Khan and Indra Reddy Inside Pharmacy: Anatomy of a Profession Ray Gosselin, Jack Robbins, and Joseph Cupolo Understanding Medical Terms: A Guide for Pharmacy Practice, Second Edition Mary Stanaszek, Walter Stanaszek, and Robert Holt Pharmacokinetic Analysis: A Practical Approach Peter Lee and Gordon Amidon Guidebook for Patient Counseling Harvey Rappaport, Tracey Hunter, Joseph Roy, and Kelly Straker Managing Pharmacy Practice: Principles, Strategies, and Systems Andrew M. Peterson Essentials of Human Physiology for Pharmacy Laurie Kelly Essentials of Human Physiology for Principles, Strategies, and Systems Pharmacy LAURIE KELLY CRC PR ESS Boca Raton London New York Washington, D.C. TX69973_C00.fm Page iv Monday, March 8, 2004 10:35 AM This edition published in the Taylor & Francis e-Library, 2005. “To purchase your own copy of this or any of Taylor & Francis or Routledge’s collection of thousands of eBooks please go to www.eBookstore.tandf.co.uk.” Library of Congress Cataloging-in-Publication Data Kelly, Laurie J. Essentials of human physiology for pharmacy / by Laurie J. Kelly p. ; cm. — (CRC Press pharmacy education series) Includes bibliographical references and index. ISBN 1-56676-997-3 (alk. paper) 1. Human physiology. 2.Pharmacy. I. Title. II. Series. [DNLM: 1. Physiological Processes. 2. Pharmaceutical Preparations. 3. Pharmacy—methods. QT 4 K29e 2004] QP34.5K45 2004 612—dc22 2003070029 This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage or retrieval system, without prior permission in writing from the publisher. The consent of CRC Press LLC does not extend to copying for general distribution, for promotion, for creating new works, or for resale. Specific permission must be obtained in writing from CRC Press LLC for such copying. Direct all inquiries to CRC Press LLC, 2000 N.W. Corporate Blvd., Boca Raton, Florida 33431. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation, without intent to infringe. Visit the CRC Press Web site at www.crcpress.com © 2004 by CRC Press LLC No claim to original U.S. Government works International Standard Book Number 1-56676-997-3 Library of Congress Card Number 2003070029 ISBN 0-203-49533-0 Master e-book ISBN ISBN 0-203-59198-4 (Adobe eReader Format) TX69973_C00.fm Page v Monday, March 8, 2004 10:35 AM Dedication To my sister, Kit, my nieces, Katie and Danielle, and especially to Tat, whose love and support mean everything in the world to me. (cid:149)¥9 TX69973_C00.fm Page vi Monday, March 8, 2004 10:35 AM TX69973_C00.fm Page vii Monday, March 8, 2004 10:35 AM Preface This textbook is designed to provide the fundamentals of human physiology to students of pharmacy and other health sciences. An important goal of this book is to enhance students’ perceptions of the relevance of physiology to pharmacy practice. The book includes important concepts in physiology described in sufficient detail so that the student may integrate and under- stand these principles and then be able to apply them in subsequent course- work in pharmacology and therapeutics. Furthermore, this text contains frequent and specific references to pharmacotherapeutics and the practice of pharmacy designed to facilitate students’ understanding of basic physiological concepts and their pertinence to their chosen profession. The book begins with an overview of the fundamental aspects of cell membrane physiology with particular emphasis on nerve cell function. This is followed by a detailed discussion of the two major regulatory systems in the body: the nervous system, including the brain, spinal cord, pain, and autonomic nervous system; as well as the endocrine system. The book then continues with in-depth presentations of the muscular, cardiovascular, res- piratory, digestive, and renal systems. An important focus throughout this textbook is how tissue and organ function is regulated in order to maintain homeostasis. The intent of this book is to present the material in a manner as clear and concise as possible. Study objectives are provided at the beginning of each chapter to help students focus on important principles and mechanisms. Whenever possible, information is provided in the form of bulleted lists, tables, figures, or flow charts. Finally, subsections of pharmacy applications separate from the text serve to relate a given concept in physiology to the practice of pharmacy. Laurie J. Kelly Massachusetts College of Pharmacy and Health Sciences TX69973_C00.fm Page viii Monday, March 8, 2004 10:35 AM TX69973_C00.fm Page ix Monday, March 8, 2004 10:35 AM Acknowledgments Thanks to Althea Chen, who prepared the illustrations for this book, and to Gail Williams, who prepared the tables.