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Essential microbiology for wound care PDF

193 Pages·2016·5.638 MB·English
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Essential Microbiology for Wound Care Essential Microbiology for Wound Care Edited by Valerie Edwards-Jones Emeritus Professor of Medical Microbiology School of Healthcare Science Manchester Metropolitan University, UK Clinical Director, MelBec Microbiology Ltd, Haslingden Rossendale, Lancashire, UK 1 9780198716006-Edwards-Jones.indb 3 27/11/15 11:42 AM 1 Great Clarendon Street, Oxford, OX2 6DP, United Kingdom Oxford University Press is a department of the University of Oxford. It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. Oxford is a registered trade mark of Oxford University Press in the UK and in certain other countries © Oxford University Press 2016 The moral rights of the author have been asserted First Edition published in 2016 Impression: 1 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of Oxford University Press, or as expressly permitted by law, by licence or under terms agreed with the appropriate reprographics rights organization. Enquiries concerning reproduction outside the scope of the above should be sent to the Rights Department, Oxford University Press, at the address above You must not circulate this work in any other form and you must impose this same condition on any acquirer Published in the United States of America by Oxford University Press 198 Madison Avenue, New York, NY 10016, United States of America British Library Cataloguing in Publication Data Data available Library of Congress Control Number: 2015944342 ISBN 978–0–19–871600–6 Printed and bound by CPI Group (UK) Ltd, Croydon, CR0 4YY Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up-to-date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breast-feeding Links to third party websites are provided by Oxford in good faith and for information only. Oxford disclaims any responsibility for the materials contained in any third party website referenced in this work. Foreword by Gregory Schultz Optimal care of both acute and chronic wounds requires effective manage- ment of the bacterial bioburden, yet many wound care providers (physicians, nurses, and podiatrists) have limited training in basic aspects of micro- biology, which reduces their effectiveness in selecting and using advanced wound care products. This ‘gap in their knowledge base’ can result in incon- sistent or suboptimal wound care that can lead to substantial complications including sepsis or amputations. Fortunately, the new text ‘Essential Microbiology for Wound Care’ edited by Valerie Edwards-Jones, Emeritus Professor of Medical Microbiology, and former Director of Research at Manchester Metropolitan University, UK, is a major aid in filling this knowledge gap for wound care providers. Professor Edwards- Jones has enlisted a very distinguished list of contributors who are leaders in their areas of microbiology and clinical wound care. The list of topics spans the spectrum from the basic science of microbiology to clinical translation of the key principles into effective wound care. These include chapters on new devel- opments in understanding bacterial biofilms, advances in antimicrobial agents, descriptions of antimicrobial dressing used in wound care, strategies to reduce wound infection and to optimize treatments for infected wounds. Busy clinicians will find the structure of the chapters to be very ‘user- friendly’. Each chapter includes a concise list of the important information covered in the chapter and a summary of the key facts discussed and written in terms the non-microbiologist can readily understand. This new text is highly recommended for both new and experienced wound care clinicians because it effectively bridges the knowledge gap that often exists between understanding basic microbiology and effective trans- lation into prevention of wound infection or effective clinical management of wound bioburden. Professor Gregory Schultz, PhD Department of Obstetrics and Gynecology Institute for Wound Research University of Florida, USA Foreword by Sue Bale The publication of this book is so timely with the growth in discussion and debate surrounding the importance of infection, microbial resistance, and the challenges associated with developing new antibiotics and alterna- tive therapies. The risk of wound infection is a constant clinical challenge, which can delay healing for individual patients, affect their quality of life, whilst adversely impacting on health systems’ economies. The early detec- tion of infection by deploying the best diagnostics will help clinical staff to move quickly to treat infection, thus reducing its economic and personal costs. Our knowledge of the role of biofilms in wounds has emerged over the past 10 years, alongside the negative effects of biofilms throughout other sites in the human body. Effective recognition, detection and management of bio- films in wounds that is underpinned by sound knowledge, and the clinical experiences of experts will be key to providing the best clinical care possible for patients. If we can bring together the knowledge and experience of ex- pert wound healing professionals with the research of laboratory and clinical scientists then we will be well on the way to transforming recalcitrant, non- healing wounds into healed wounds. At a practical level many wounds require a dressing to manage exudates, drainage, pain, and cosmesis. When infection and bacterial burden is also present, decisions about which of the many dressings to use can be chal- lenging. Clinical staff need to be aware of the indications of use, functions, application and contraindications of these dressings if they are to effectively utilize them to effectively manage infection and bacterial burden. As science moves forward and progress is made to improve interven- tions for patients, it is essential that these discoveries are brought together and assimilated and then compared and contrasted with existing treat- ments. ‘Essential Microbiology for Wound Care’ does this, garnering the expertise of researchers and clinical leaders, who as authors have contrib- uted to this text. This book guides clinical staff in managing the broad range of clini- cal challenges that relate to bacteria and wounds and it is hugely relevant to these healthcare professionals. The effects of applying the knowledge, FoREwoRD BY SUE BALE vii information, and guidance contained within this book will no doubt help to prevent complications associated with microbes, which can be serious and life threatening. Professor Sue Bale, OBE FRCN, PhD, BA, RGN, NDN, RHV, PG Dip, Dip N Research and Development Director Aneurin Bevan University Health Board St Cadoc’s Hospital Newport, UK Preface This book is aimed at the wound care practitioner and hopefully will give an understanding of the role of microorganisms in the healing process and how colonization and infection can impede this. The various chapters describe fundamental principles of microbiology and most examples are focused around wound care. However, in order to ensure full understanding, alternative examples are also used to emphasize a par- ticular principle. The book is written in such a style that certain aspects can be revisited in order to aid understanding of some microbiological problems. The object- ives of each chapter are listed and throughout the chapters key important points are highlighted, as are interesting facts. All the authors are experts in their own fields and they have written their chapters to help you understand the full impact of microbiology and wound care. Enjoy reading . . .

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