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Essays in Economics and Education Citation Turley, Patrick Ansel. 2016. Essays in Economics and Education. Doctoral dissertation, Harvard University, Graduate School of Arts & Sciences. Permanent link http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493510 Terms of Use This article was downloaded from Harvard University’s DASH repository, and is made available under the terms and conditions applicable to Other Posted Material, as set forth at http:// nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA Share Your Story The Harvard community has made this article openly available. Please share how this access benefits you. Submit a story . Accessibility Essays in Economics and Education A dissertation presented by Patrick Ansel Turley to The Department of Economics in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the subject of Economics Harvard University Cambridge, Massachusetts May 2016 © 2016 Patrick Ansel Turley All rights reserved. Dissertation Advisor: Professor David Laibson Patrick Ansel Turley Essays in Economics and Education Abstract Education is a fundamental input of human capital formation. In this dissertation we explore topics related to how much and what time of human capital individuals invest in, and the long term-consequences of these investments. We begin with by measuring the degree to which financial incentives can affect a college student’s field of study. Next, we attempt to identify genetic variants associated with increased educational attainment and examine the biological systems implicated by this analysis. Last, we test for heterogeneous treatment effects of education on health across the distribution of observed health and across a genetic predictor of health. In chapter 1, we examine whether students respond to immediate financial incentives when choosing their college major. From 2006-07 to 2010-11, low-income students in technical or foreign language majors could receive up to $8,000 in SMART Grants. Since income- eligibility was determined using a strict threshold, we determine the causal impact of this grant on student major with a regression discontinuity design. Using administrative data from public universities in Texas, we determine that income-eligible students were 3.2 percentage points more likely than their ineligible peers to major in targeted fields. We measure a larger impact of 10.2 percentage points at Brigham Young University. iii In chapter 2 we find that, educational attainment (EA) is strongly influenced by social and other environmental factors, but genetic factors are also estimated to account for at least 20% of the variation across individuals. We report the results of a genome-wide association study (GWAS) for EA that extends our earlier discovery sample of 101,069 individuals to 293,723 individuals, and a replication in an independent sample of 111,349 individuals from the UK Biobank. We now identify 74 genome-wide significant loci associated with number of years of schooling completed. Single-nucleotide polymorphisms (SNPs) associated with educational attainment are disproportionately found in genomic regions regulating gene expression in the fetal brain. Candidate genes are preferentially expressed in neural tissue, especially during the prenatal period, and enriched for biological pathways involved in neural development. Our findings demonstrate that, even for a behavioral phenotype that is mostly environmentally determined, a well-powered GWAS identifies replicable associated genetic variants that suggest biologically relevant pathways. Because EA is measured in large numbers of individuals, it will continue to be useful as a proxy phenotype in efforts to characterize the genetic influences of related phenotypes, including cognition and neuropsychiatric disease. In 1972, the mandatory minimum age at which a student could drop out of school in England and Wales was raised from 15 to 16, constraining roughly 15 percent of the student population. In chapter 3, we exploit this discontinuous increase in educational attainment to estimate the impact of education on body mass index (BMI) and diabetes approximately 40 years later. While previous literature found no significant effect of education on health, they were not able to investigate whether these effects vary along the distribution of health outcomes. We are able to detect large effects on BMI in the upper quantiles of observed BMI, as large as 2 BMI points at the 90th percentile of BMI, from a baseline of 35.6. Using a genetic predictor of BMI, iv we also find that those with higher genetic risk of obesity see smaller reductions in BMI as a result of the increase in compulsory schooling while large reductions are seen in those with low genetic risk. Taken together our results point to the importance of considering heterogeneity when estimating the impacts of education on health. v Table of Contents Front Matter ..................................................................................................................................... i Title page ................................................................................................................................... i Copyright page .......................................................................................................................... ii Abstract .................................................................................................................................... iii Table of Contents ..................................................................................................................... vi List of Figures ......................................................................................................................... vii List of Tables ......................................................................................................................... viii Acknowledgements .................................................................................................................. ix Chapter 1 ..........................................................................................................................................1 I. Introduction ............................................................................................................................2 II. The SMART Grant Program .................................................................................................7 III. Data ....................................................................................................................................10 IV. Identification ......................................................................................................................15 V. Results .................................................................................................................................23 VI. Conclusion .........................................................................................................................50 Chapter 2 ........................................................................................................................................53 Chapter 3 ........................................................................................................................................78 I. Introduction ..........................................................................................................................79 II. Institutional Background .....................................................................................................83 III. Data ....................................................................................................................................84 IV. Mean Effect of Education on Health .................................................................................91 V. Heterogeneous Effects ......................................................................................................105 VI. Genetic Heterogeneity .....................................................................................................117 VII. Robustness ......................................................................................................................137 VIII. Discussion .....................................................................................................................142 IX. Conclusion .......................................................................................................................146 References ....................................................................................................................................148 vi List of Figures Chapter 1 Figure 1.1: Covariate Checks ........................................................................................................ 21 Figure 1.2: Total SMART Grant, SMART Majors ....................................................................... 25 Figure 1.3: Ever Receive SMART Grant....................................................................................... 26 Figure 1.4: SMART Major in Junior Year .................................................................................... 32 Figure 1.5: SMART Major in Senior Year .................................................................................... 33 Figure 1.6: SMART Degrees ......................................................................................................... 34 Figure 1.7: Fraction SMART Classes—BYU Only ...................................................................... 35 Figure 1.8: Estimates by Year ....................................................................................................... 42 Figure 1.9: Various Bandwidths .................................................................................................... 48 Chapter 2 Figure 2.1: Manhattan Plot ............................................................................................................ 57 Figure 2.2: Quantile-quantile Plot ................................................................................................. 58 Figure 2.3: TheDdistribution of Effect Sizes ................................................................................. 59 Figure 2.4: Assessing Population Stratification ............................................................................ 61 Figure 2.5: Replication .................................................................................................................. 62 Figure 2.6: Genetic Correlations .................................................................................................... 64 Figure 2.7: Q-Q plots of Other Phenotypes ................................................................................... 65 Figure 2.8: Regional Association Plots ......................................................................................... 66 Figure 2.9: Tissue-level Biological Annotation ............................................................................. 68 Figure 2.10: Overview of Biological Annotation .......................................................................... 70 Figure 2.11: Gene-level Biological Annotation ............................................................................. 72 Figure 2.12: PredictivePpower of PGS in Sweden by Birth Cohort .............................................. 76 Chapter 3 Figure 3.1: Geographic Distribution of the BMI Genetic Score .................................................... 92 Figure 3.2: McCrary Test Scatter Plot ........................................................................................... 96 Figure 3.3: Balance Tests .............................................................................................................. 97 Figure 3.4: Fraction in School till Various Ages by Date of Birth .............................................. 100 Figure 3.5: RD Estimates for Fraction in School till Various Ages ............................................ 101 Figure 3.6: Mean BMI by Date of Birth ...................................................................................... 104 Figure 3.7: Fraction with Self-reported Diabetes by Date of Birth ............................................. 106 Figure 3.8: Various Quantiles of BMI by Date of Birth .............................................................. 111 Figure 3.9: The Effect of the 1972 ROSLA on the Distribution of BMI .................................... 112 Figure 3.10: Effect of School Till Age 16 on the Distribution of BMI (Compliers) ................... 114 Figure 3.11: RD Estimates for Fraction with a BMI above Thresholds ...................................... 115 Figure 3.12: 2SLS Estimates for Fraction with a BMI above Thresholds ................................... 116 Figure 3.13: RD Estimates for Fraction with a BMI above Thresholds (Rescaled) .................... 118 Figure 3.14: First-Stage Estimates by Genetic BMI Score Tercile ............................................. 122 Figure 3.15: Reduced-Form Estimates for BMI by Genetic BMI Score Tercile ......................... 124 Figure 3.16: Reduced-Form for the 90th P-tile of BMI by Genetic BMI Score Tercile ............. 126 Figure 3.17: Reduced-Form Estimates for Diabetes by Genetic BMI Score Tercile .................. 129 Figure 3.18: The Effect of Staying in School till Age 16 on BMI by BMI Score Tercile........... 131 Figure 3.19: The Effect of Staying in School till Age 16 on Diabetes by BMI Score Tercile .... 132 Figure 3.20: Bandwidth Analysis of First Stage .......................................................................... 138 Figure 3.21: Bandwidth Analysis of Reduced-Form (BMI) ........................................................ 139 Figure 3.22: Bandwidth Analysis of Reduced-Form (90th Percentile of BMI) .......................... 140 Figure 3.23: Bandwidth Analysis of Reduced-Form (Diabetes) ................................................. 141 vii List of Tables Chapter 1 Table 1.1: Summary Statistics ................................................................................................12 Table 1.2: SMART Grant Receipt ...........................................................................................27 Table 1.3: Effects on Major .....................................................................................................30 Table 1.4: Yearly Discontinuities ............................................................................................39 Table 1.5: STEM and Language Outcomes .............................................................................45 Table 1.6: Heterogeneity by Sophomore Major ......................................................................49 Chapter 2 Table 2.1: Selected candidate genes implicated by bioinformatics analyses ...........................74 Chapter 3 Table 3.1: Summary Statistics .................................................................................................87 Table 3.2: McCrary Test and Balance Tests ............................................................................98 Table 3.3: First-Stage Estimates ............................................................................................102 Table 3.4: Mean Effect of Education on BMI .......................................................................103 Table 3.5: Mean Effect of Education on Diabetes .................................................................107 Table 3.6: Genetic Heterogeneity in the First-Stage ..............................................................121 Table 3.7: Genetic Heterogeneity in the Reduced-Form for BMI .........................................123 Table 3.8: Genetic Heterogeneity in the Reduced-Form for the 90th Percentile of BMI ......125 Table 3.9: Genetic Heterogeneity in the Reduced-Form for Diabetes...................................128 Table 3:10: Genetic Heterogeneity in the 2SLS Estimates for BMI and Diabetes ................130 Table 3.11: Selected Genetic Correlations with BMI ............................................................134 Table 3.12: The Common Contributions to Heterogeneity of the BMI and EA Scores ........136 Table 3.13: Local Linear versus Global Polynomial .............................................................143 viii Acknowledgments For their help in completing this dissertation and support during my graduate years, thanks to my committee David Laibson, Larry Katz, and Dan Benjamin. And a very special thanks to Jonathan Jala, who help proof-read this document and who has supported me through the ups and downs of the years. For chapter 1, we would like to thank the Texas Higher Education Coordinating Board and Brigham Young University for providing the data. We also would like to thank two anonymous referees, Sandra Black, Lawrence Katz, Dayanand Manoli, Amanda Pallais, Carole Voulgaris, Robert Turley, participants in the University of Texas at Austin Labor Lunch, the Education and Transition to Adulthood Group of the Population Research Center at the University of Texas at Austin, and participants at the STATA Texas Empirical Micro Conference for helpful comments on the draft. We would also like to thank Kelli Bird for data on the timing of FAFSA filing. The research for chapter 2 was carried out under the auspices of the Social Science Genetic Association Consortium (SSGAC). The SSGAC seeks to facilitate studies that investigate the influence of genes on human behavior, well-being, and social-scientific outcomes using large genome-wide association study meta-analyses. The SSGAC also provides opportunities for replication and promotes the collection of accurately measured, harmonized phenotypes across cohorts. The SSGAC operates as a working group within the CHARGE consortium. This research has also been conducted using the UK Biobank Resource. This study was supported by funding from the Ragnar Söderberg Foundation (E9/11), the Swedish Research Council (421-2013-1061), The Jan Wallander and Tom Hedelius Foundation, an ERC Consolidator Grant (647648 EdGe), the Pershing Square Fund of the Foundations of Human ix

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2016. Essays in Economics and Education. Doctoral to. The Department of Economics in partial fulfillment of the requirements for the degree of. Doctor of Philosophy in the subject of. Economics. Harvard receptor), the sprouting of dendrites and their spines (dendrite, dendritic spine organization
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