Enzymatic Transformation

299 Pages·2013·8.841 MB·English

by  Soundar Divakar (auth.)

Enzymatic Transformation

Soundar Divakar
Enzymatic
Transformation
Soundar Divakar
Central Food Technological Research Institute
Mysore, Karnataka , India
ISBN 978-81-322-0872-3 ISBN 978-81-322-0873-0 (eBook)
DOI 10.1007/978-81-322-0873-0
Springer New Delhi Heidelberg New York Dordrecht London
Library of Congress Control Number: 2012951119
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Viky and Sasi

Preface
This book is a summary of the research work carried out by me with my
students and collaborators at the Central Food Technological Research Institute,
Mysore, India. The work was carried out in a period spanning 18 years or so
from 1995 onwards. The essence of the work from 70 or so publications is
presented here in brief under 11 chapters.
The objective of this book is to explain the various techniques and strategies
involved in enzymatic transformation reactions. Esteri fi cation of acids using
lipases and glycosylation of alcohols and phenols using glycosidases are the
two enzymatic reactions highlighted in this book. Both esteri fi cation and
glycosylation reactions involve multifunctional substrates. Challenges using
underivatised polar and nonpolar substrates in terms of product speci fi city/
selectivity, yields and feasibility in such enzymatic reactions carried out in
nonpolar media are explained with several examples of divergent multifunc-
tional substrates. Hence, the information provided would be a source of useful
information for not only established researchers but also for beginners who
eye this as a potential and fruitful research area.
The author is sure that this book has brought out the trials and tribulations
of carrying out enzymatic transformations clearly.
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About the Author
Dr. Divakar is working as a Chief Scientist in the Central Food Technological
Research Institute, Mysore, where he joined as a Scientist. Before this, he
served as CSIR Pool Of fi cer at Molecular Biophysics Unit, Indian Institute
of Science, Bangalore. After completing his post-graduation in 1976 from
Pachaiyappa’s College, Chennai, he had a brief stint in a polymer industry,
M/S Reichhold Chemicals, Ind. Ltd., Chennai. He completed his Ph.D.
degree in Chemistry from the Australian National University, Canberra,
Australia in 1982.
The author is actively involved in research for the past 36 years. While
working as a Research and Development chemist at Ms. Reichhold Chemicals
(Ind.) Ltd., he was actively involved in research in the fi e lds of alkyd resins,
unsaturated polyesters, phenol-formaldehyde resins (resoles and novolaks),
urea-formaldehyde resins and epoxy resins.
After completing his Ph.D., he was involved in research work on three
important areas, namely,
1. NMR investigations of some biological systems
2. Host-guest complexation chemistry with special reference to cyclodextrins
3. Enzyme catalyzed transformation reaction employing lipases and
glycosidases
He has so far guided various Ph.D. and M.Sc. students and has published
about 149 research articles including reviews. His work on Enzymatic
Transformations has resulted in about 70 publications, which prompted him
to write this book on Enzymatic Transformation.
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