Endocrine secrets PDF
Preview Endocrine secrets
ENDOCRINE ENDOCRINE Sixth Edition Michael T. McDermott, MD Professor of Medicine and Clinical Pharmacy University of Colorado Denver School of Medicine Director, Endocrinology and Diabetes Practice University of Colorado School of Medicine Denver, Colorado 1600 John F. Kennedy Blvd. Ste. 1800 Philadelphia, PA 19103-2899 ENDOCRINE SECRETS ISBN: 978-1-4557-4975-1 Copyright © 2013 by Saunders, an imprint of Elsevier Inc. Copyright © 2009, 2005, 2002, 1998, 1994 by Mosby, Inc., an affiliate of Elsevier Inc. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions. This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility. With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Library of Congress Cataloging-in-Publication Data McDermott, Michael T., 1952- Endocrine secrets / Michael T. McDermott. — 6th ed. p. ; cm. — (Secrets series) Includes bibliographical references and index. ISBN 978-1-4557-4975-1 (pbk.) I. Title. II. Series: Secrets series. [DNLM: 1. Endocrine System Diseases—physiopathology—Examination Questions. WK 18.2] RC649 616.40076—dc23 2013002954 Senior Content Strategist: James Merritt Content Development Specialist: Lisa Barnes Publishing Services Managers: Hemamalini Rajendrababu and Jeffrey Patterson Project Managers: Saravanan Thavamani and William Drone Design Manager: Steven Stave Marketing Manager: Abigail Swartz Printed in the United States of America Last digit is the print number: 9 8 7 6 5 4 3 2 1 This book is dedicated to Libby and Emily, whose courageous battles with conditions they did not want to have are a continuing source of inspiration and strength for all of us. CONTRIBUTORS Arnold A. Asp, MD Henry B. Burch, MD Chief, Endocrinology Chair, Endocrinology Division and Professor of Medicine Gundersen-Lutheran Uniformed Services La Crosse, Wisconsin University of the Health Sciences Endocrinology Service Linda A. Barbour, MD Walter Reed National Military Medical Center Professor of Medicine and Obstetrics and Gynecology Bethesda, Maryland Divisions of Endocrinology, Metabolism, and Diabetes and Maternal-Fetal Medicine Ana-Maria Chindris, MD Medical Director of Diabetes and High Risk Obstetric Endocrinology Fellow Clinics Division of Endocrinology University of Colorado School of Medicine Mayo Clinic Aurora, Colorado Jacksonville, Florida Brenda K. Bell, MD Reed S. Christensen, MD Clinical Endocrinologist LTC US Army Private Practice Madigan Army Medical Center Lincoln, Nebraska Tacoma, Washington Daniel H. Bessesen, MD Scott A. Clements, MD Chief of Endocrinology Physician Denver Health Medical Center Pediatric Endocrinology Professor of Medicine Children’s Hospital Colorado University of Colorado School of Medicine Aurora, Colorado Associate Director Jason Daily, MD Anschutz Health and Wellness Center Assistant Professor Aurora, Colorado Department of Medicine Mark Bridenstine, MD Uniformed Services University of the Health Sciences Endocrinology Fellow Bethesda, Maryland Endocrinology, Diabetes, and Metabolism Department of Endocrinology University of Colorado School of Medicine Navy Medical Center Portsmouth Aurora, Colorado Portsmouth, Virginia Tamis M. Bright, MD Ryan M. Decort, MD Chief, Division of Endocrinology Internal Medicine Physician, US Army Internal Medicine William Beaumont Army Medical Center Texas Tech University El Paso, Texas El Paso, Texas Boris Draznin, MD Heather E. Brooks, MD Director, Adult Diabetes Program Endocrinologist Celeste and Jack Grynberg Professor of Medicine University of Pittsburgh Physicians Division of Endocrinology, Metabolism and Diabetes Center for Diabetes and Endocrinology University of Colorado School of Medicine Pittsburgh, Pennsylvania Aurora, Colorado vii viii CONTRIBUTORS William E. Duncan, MD, PhD Thanh D. Hoang, DO Professor of Medicine Assistant Professor Uniformed Services University Department of Medicine Bethesda, Maryland Uniformed Services University of the Health Sciences Bethesda, Maryland James E. Fitzpatrick, MD Staff Endocrinologist Professor Endocrinology Department of Dermatology Naval Medical Center Portsmouth University of Colorado School of Medicine Portsmouth, Virginia Aurora, Colorado Robert E. Jones, MD Col. William C. Frey, MD Professor of Medicine Pulmonary, Critical Care, Sleep Medicine Service Endocrinology Division Brooke Army Medical Center University of Utah School of Medicine Fort Sam Houston, Texas Salt Lake City, Utah William J. Georgitis, MD Joshua Klopper, MD Clinical Professor Assistant Professor of Medicine and Radiology Division of Endocrinology Department of Medicine - Division of Endocrinology, University of Colorado School of Medicine Metabolism and Diabetes Aurora, Colorado University of Colorado School of Medicine Gary Goldenberg, MD Aurora, Colorado Assistant Professor, Dermatology and Pathology Wendy M. Kohrt, PhD Mount Sinai School of Medicine Professor of Medicine Medical Director of the Dermatology Faculty Practice Division of Geriatric Medicine New York, New York University of Colorado School of Medicine Sky D. Graybill, MD Denver, Colorado Endocrinologist Pratima Kumar, MD San Antonio Military Medical Center Assistant Professor Fort Sam Houston, Texas Endocrinology Marissa Grotzke, MD University of Texas Southwestern Austin Residency Assistant Professor Program University of Utah Health Care Austin, Texas Salt Lake City, Utah Homer J. LeMar Jr., MD Bryan R. Haugen, MD Chief of Staff Professor of Medicine and Pathology El Paso Veterans Affairs Health Care System Head, Division of Endocrinology, Metabolism and El Paso, Texas Diabetes Elliot G. Levy, MD Mary Rossick Kern and Jerome H. Kern Chair of Clinical Professor of Medicine Endocrine Neoplasms Research Division of Endocrinology University of Colorado School of Medicine University of Miami Miller School of Medicine Aurora, Colorado Miami, Florida James V. Hennessey, MD Michael T. McDermott, MD Associate Professor of Medicine Professor of Medicine and Clinical Pharmacy Medicine/Endocrinology University of Colorado School of Medicine Harvard Medical School Director, Endocrinology and Diabetes Practice Clinical Director University of Colorado Hospital Medicine/Endocrinology Denver, Colorado Beth Israel Deaconess Medical Center Boston, Massachusetts CONTRIBUTORS ix Robert C. McIntyre, MD Anil Piya, MD Professor of Surgery Fellow, Pediatric Endocrinology University of Colorado School of Medicine University of Colorado Denver, Colorado Division of Pediatric Endocrinology Childrens Hospital Colorado Peter Z. McIntyre, MD Aurora, Colorado Teaching Fellow in Medicine Uniformed Services University of the Health Sciences Christopher D. Raeburn, MD Endocrine Fellow Associate Professor of Surgery Department of Internal Medicine, Divison of GI, Tumor and Endocrine Surgery Endocrinology and Metabolism University of Colorado School of Medicine Walter Reed National Military Medical Center Aurora, Colorado Bethesda, Maryland Micol S. Rothman, MD Shon Meek, MD, PhD Assistant Professor of Medicine Assistant Professor of Medicine Endocrinology, Diabetes and Metabolism Department of Endocrinology University of Colorado School of Medicine Mayo Clinic Aurora, Colorado Jacksonville, Florida Mary H. Samuels, MD Alexandra L. Migdal, MD Professor of Medicine Department of Internal Medicine Oregon Health & Science University Beth Israel Deaconess Medical Center Portland, Oregon Boston, Massachusetts Leonard R. Sanders, MD, FACP Stephanie B. Ng, DO Medical Director Internal Medicine Physician Diabetes and Dialysis Internal Medicine Gila River Health Care Landstuhl Regional Medical Center Sacaton, Arizona APO AE, Germany Virginia Sarapura, MD Wesley Nuffer, PharmD Associate Professor Assistant Professor Medicine-Endocrinology Department of Clinical Pharmacy University of Colorado School of Medicine University of Colorado Skaggs School of Pharmacy & Aurora, Colorado Pharmaceutical Sciences Jonathan A. Schoen Aurora, Colorado Associate Professor of Surgery John J. Orrego, MD Director of Surgical Weight Loss Center Endocrinologist University of Colorado Hospital Endocrinology and Metabolism Anschultz Medical Center Kaiser Permanente Aurora, Colorado Denver, Colorado Emily Schroeder, MD, PhD Samir J. Patel, MD Division of Endocrinology Assistant Professor Kaiser Permanente University of Nevada School of Medicine Denver, Colorado Department of Internal Medicine Assistant Professor of Medicine Las Vegas, Nevada Division of Endocrinology, Diabetes and Metabolism University of Colorado School of Medicine Roger A. Piepenbrink, DO, MPH, FACP Aurora, Colorado Chief, Adult Endocrinology Metabolism & Diabetes Mike O’Callaghan Federal Medical Center Nellis Air Force Base Las Vegas, Nevada x CONTRIBUTORS Robert S. Schwartz, MD Robert A. Vigersky, MD Goodstein Professor of Medicine/Geriatrics Director, Diabetes Insitute Head, Division of Geriatric Medicine Endocrinology and Metabolism Service Director, Center on Aging Walter Reed National Military Medical Center University of Colorado School of Medicine Professor of Medicine Aurora, Colorado Uniformed Services University of the Health Sciences Bethesda, Maryland Stacey A. Seggelke, RN, MS, CNS Instructor of Medicine Vanya D. Wagler Department of Medicine, Division of Endocrinology William Beaumont Army Medical Center University of Colorado Denver El Paso, Texas Aurora, Colorado Cecilia C. Low Wang, MD, FACP Kenneth J. Simcic, MD† Associate Professor of Medicine Formerly Assistant Professor Associate Director, Fellowship/Education Division of Endocrinology Division of Endocrinology, Metabolism and Diabetes Department of Medicine University of Colorado School of Medicine University of Texas Health Science Center at San Antonio Aurora, Colorado San Antonio, Texas Katherine Weber, MD Robert H. Slover, MD Endocrinologist Director of Pediatrics Department of Endocrinology The Barbara Davis Center for Diabetes Kaiser Permanente University of Colorado School of Medicine Denver, Colorado Aurora, Colorado Margaret E. Wierman, MD Robert C. Smallridge, MD Professor of Medicine Chair, Endocrinology University of Colorado School of Medicine Mayo Clinic Aurora, Colorado Jacksonville, Florida Amy A. Yau, MD Sandra I. Sobel, MD Resident Physician Endocrinology Fellow Department of Internal Medicine Department of Medicine William Beaumont Army Medical Center University of Pittsburgh Medical Center El Paso, Texas Pittsburgh, Pennsylvania Philip Zeitler, MD, PhD Elizabeth A. Thomas, MD Professor and Head, Section of Endocrinology Fellow Department of Pediatrics Endocrinology, Metabolism and Diabetes University of Colorado School of Medicine University of Colorado School of Medicine Chair, Department of Endocrinology Denver, Colorado Children’s Hospital Colorado Aurora, Colorado Sharon Travers, MD Associate Professor Kimberly C. Zibert, DO Pediatric Endocrinology Internal Medicine Childrens Hospital Colorado/University of Colorado Madigan Army Medical Center Denver Tacoma, Washington Aurora, Colorado Jennifer M. Trujillo, PharmD, BCPS Associate Professor Department of Clinical Pharmacy University of Colorado Aurora, Colorado †Deceased.
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