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Endocrine and metabolic medical emergencies : a clinician's guide PDF

822 Pages·2018·13.87 MB·English
by  Matfin
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EndocrineandMetabolicMedicalEmergencies Idedicatethisbooktoallpeoplelivingwithendocrineandmetabolicproblemsandthe healthcareprofessionalswholookafterthem.Ialsodedicatethisbooktomyfamily,especially wifeMarciaandparentsEnidandSid,withoutwhosecontinuedsupportandencouragement thebookwouldneverhavebeenstartednevermindfinished! Endocrine and Metabolic Medical Emergencies AClinician’sGuide Editedby GlennMatfin,BSc(Hons),MSc(Oxon),MBChB, DGM,FACE,FACP,FRCP ConsultantinAcuteandGeneralMedicine,DiabetesandEndocrinology HonoraryProfessorofMedicine NationalHealthService,UK ProfessorofMedicine MBRUCollegeofMedicine DubaiHealthcareCity Dubai,UAE SecondEdition ThisWorkisaco-publicationbetweentheEndocrineSocietyandJohnWiley&Sons,Ltd. Thisfirstpublished2018 ©2018JohnWiley&SonsLtd ThisWorkisaco-publicationbetweentheEndocrineSocietyandJohnWiley&Sons,Ltd. EditionHistory EndocrineSociety/EndocrinePress(1e,2014) Allrightsreserved.Nopartofthispublicationmaybereproduced,storedinaretrievalsystem,ortransmitted,inany formorbyanymeans,electronic,mechanical,photocopying,recordingorotherwise,exceptaspermittedbylaw. Adviceonhowtoobtainpermissiontoreusematerialfromthistitleisavailableat http://www.wiley.com/go/permissions. TherightofGlennMatfintobeidentifiedastheauthorofthisworkhasbeenassertedinaccordancewithlaw. RegisteredOffice(s) JohnWiley&Sons,Inc.,111RiverStreet,Hoboken,NJ07030,USA JohnWiley&SonsLtd,TheAtrium,SouthernGate,Chichester,WestSussex,PO198SQ,UK EditorialOffice 9600GarsingtonRoad,Oxford,OX42DQ,UK Fordetailsofourglobaleditorialoffices,customerservices,andmoreinformationaboutWileyproductsvisitusat www.wiley.com. Wileyalsopublishesitsbooksinavarietyofelectronicformatsandbyprint-on-demand.Somecontentthatappears instandardprintversionsofthisbookmaynotbeavailableinotherformats. LimitofLiability/DisclaimerofWarranty Thecontentsofthisworkareintendedtofurthergeneralscientificresearch,understanding,anddiscussiononlyand arenotintendedandshouldnotberelieduponasrecommendingorpromotingscientificmethod,diagnosis,or treatmentbyphysiciansforanyparticularpatient.Inviewofongoingresearch,equipmentmodifications,changesin governmentalregulations,andtheconstantflowofinformationrelatingtotheuseofmedicines,equipment,and devices,thereaderisurgedtoreviewandevaluatetheinformationprovidedinthepackageinsertorinstructionsfor eachmedicine,equipment,ordevicefor,amongotherthings,anychangesintheinstructionsorindicationofusage andforaddedwarningsandprecautions.Whilethepublisherandauthorshaveusedtheirbesteffortsinpreparing thiswork,theymakenorepresentationsorwarrantieswithrespecttotheaccuracyorcompletenessofthecontentsof thisworkandspecificallydisclaimallwarranties,includingwithoutlimitationanyimpliedwarrantiesof merchantabilityorfitnessforaparticularpurpose.Nowarrantymaybecreatedorextendedbysalesrepresentatives, writtensalesmaterialsorpromotionalstatementsforthiswork.Thefactthatanorganization,website,orproductis referredtointhisworkasacitationand/orpotentialsourceoffurtherinformationdoesnotmeanthatthepublisher andauthorsendorsetheinformationorservicestheorganization,website,orproductmayprovideor recommendationsitmaymake.Thisworkissoldwiththeunderstandingthatthepublisherisnotengagedin renderingprofessionalservices.Theadviceandstrategiescontainedhereinmaynotbesuitableforyoursituation. Youshouldconsultwithaspecialistwhereappropriate.Further,readersshouldbeawarethatwebsiteslistedinthis workmayhavechangedordisappearedbetweenwhenthisworkwaswrittenandwhenitisread.Neitherthe publishernorauthorsshallbeliableforanylossofprofitoranyothercommercialdamages,includingbutnotlimited tospecial,incidental,consequential,orotherdamages. LibraryofCongressCataloging-in-PublicationData Names:Matfin,Glenn,editor. Title:Endocrineandmetabolicmedicalemergencies:aclinician’sguide/ [edited]byGlennMatfin. Description:Secondedition.|Hoboken,NJ:Wiley,2018.|Includes bibliographicalreferencesandindex.| Identifiers:LCCN2017049999(print)|LCCN2017050741(ebook)|ISBN 9781119374763(pdf)|ISBN9781119374756(epub)|ISBN9781119374732 (cloth) Subjects:|MESH:EndocrineSystemDiseases|MetabolicDiseases|Emergency Treatment Classification:LCCRC649(ebook)|LCCRC649(print)|NLMWK140|DDC 616.4–dc23 LCrecordavailableathttps://lccn.loc.gov/2017049999 Coverimages:©donskarpo/GettyImages-Thyroidlevelconceptualmeter ©shansekala/GettyImages-Stethoscopeoncardiogramconceptforheartcare ©juststock/GettyImages-HypoglycemiaPrintedDiagnosisMedicalConcept CoverdesignbyWiley Setin10/12ptWarnockProbyAptaraInc.,NewDelhi,India 1 2018 v Contents NotesonContributors x Foreword xv Preface xvi ListofAbbreviations xviii PartI GeneralAspectsofAcuteMedicalEmergencies 1 Introduction:AcuteMedicalCare:ACrisiswithSolutions 3 GlennMatfin  EarlyManagementofAcuteMedicalEmergencies 10 PaulJ.FrostandMattP.Wise PartII GeneralEndocrineandMetabolicAspectsofAcuteandCriticalIllness 21 Introduction:EndocrineTestingandResponsesinAcuteandCriticalIllness 23 DavidB.Sacks  EndocrineTestinginAcuteandCriticalIllness 28 RezaMorovat  EndocrineResponsestoCriticalIllness:NovelInsightsandTherapeutic Implications 60 JanGunst,EvaBoonen,andGreetVandenBerghe PartIII SpecialPopulations 83  EndocrineandMetabolicEmergenciesinPregnancy 85 AnitaBanerjeeandCatherineWilliamson  EndocrineandMetabolicEmergenciesinInheritedMetabolicDiseases: AcutePresentationsinAdulthood 98 ElaineMurphyandRobinH.Lachmann  EndocrineandMetabolicEmergenciesinTransitionalCare 110 MabelYauandMarkA.Sperling vi Contents  EmergencyPerioperativeDiabetesandEndocrineManagement 129 GlennMatfin,KateEvans,andKetanDhatariya  EndocrineandMetabolicEmergenciesinHIV/AIDS 151 KatherineSamaras  EndocrineandMetabolicEmergenciesinLate-EffectsPatients: ConsequencesofCancerTherapy 160 HelenaGleesonandAndrewToogood  EndocrineandMetabolicEmergenciesinTransplantation 171 RobertA.WermersandPankajShah  EndocrineandMetabolicChangeswithAging:Endocrin-Aging:Recognizing andManagingCareinOlderFrailPersons 182 AngelaM.AbbatecolaandJohnE.Morley PartIV PituitaryDisorders 195 Introduction:EmergencyManagementofPituitaryDisorders 197 EdwardR.LawsandUrsulaB.Kaiser  Hypopituitarism 203 NicholasA.TritosandAnneKlibanski  PituitaryApoplexy 218 ClaireBrietandPhilippeChanson  Macroprolactinomas 231 MarkE.Molitch PartV ThyroidDisorders 243 Introduction:EmergencyManagementofThyroidDisorders 245 HosseinGharib  MyxedemaComa 252 NatashaKasidandJamesV.Hennessey  Life-ThreateningThyrotoxicosis:ThyroidStormandAdverseEffectsof AntithyroidDrugs 262 AliciaL.Warnock,DavidS.Cooper,andHenryB.Burch  Amiodarone-InducedThyrotoxicosis 284 FaustoBogazzi,LucaTomisti,LuigiBartalena,andEnioMartino  ThyrotoxicPeriodicParalysis 296 MarkVanderpump Contents vii  Sight-ThreateningGraves’Orbitopathy 305 RebeccaS.BahnandJamesA.Garrity PartVI AdrenalDisorders 313 Introduction:EmergencyManagementofAdrenalDisorders 315 AnandVaidya  AcuteAdrenalInsufficiency 321 GlennMatfin  AcuteMedicalAspectsRelatedtoFloridCushing’sSyndrome 345 KrystalleniaI.AlexandrakiandAshleyB.Grossman  EndocrineHypertensiveEmergencies 355 GraemeEisenhofer,AndrzejJanuszewicz,ChristinaPamporaki,andJacquesW.M.Lenders PartVII Calcium,Phosphate,andMetabolicBoneDiseases 375 Introduction:EmergencyManagementofCalcium,Phosphate,andMetabolic BoneDiseases 377 JohnP.Bilezikian  Hypocalcemia 380 GlennMatfin  Hypercalcemia 400 GlennMatfin  AcuteMedicalAspectsRelatedtoPhosphateDisorders 422 AndaR.GonciuleaandSuzanneM.JandeBeur  AcuteMedicalAspectsRelatedtoOsteoporosisandItsTherapy 433 DimaL.DiabandNelsonB.Watts  AcuteMedicalAspectsRelatedtoPaget’sDiseaseofBone 447 EthelS.SirisandDorothyA.Fink  AcuteMedicalAspectsRelatedtoKidneyStones 454 HasanFattahandDavidS.Goldfarb PartVIII NeuroendocrineTumors 465 Introduction:EmergencyManagementofNeuroendocrineTumors 467 KjellOberg  AcuteEndocrineandMetabolicEmergenciesRelatedtoNeuroendocrineTumors 472 GregoryKaltsas,KrystalleniaI.Alexandraki,andAshleyB.Grossman viii Contents PartIX GlucoseDisorders 485 Introduction:EmergencyManagementofGlucoseDisorders 487 GerryRayman  ManagementofDiabetesand/orHyperglycemiainNon-CriticalCare HospitalSettings 491 RodolfoJ.GalindoandGuillermoE.Umpierrez  Hypoglycemia 506 ElizabethM.Lamos,LisaM.Younk,andStephenN.Davis  SevereHyperglycemia,DiabeticKetoacidosis,andHyperglycemic HyperosmolarState 531 KetanDhatariyaandGlennMatfin  Short-TermIntensiveInsulinTherapyinPatientswithNewlyPresenting TypeDiabetes 548 WenXu,DavidOwens,andJianpingWeng  ManagementofConcentratedInsulinsinAcuteCareSettings 560 NuhaElSayed,MeganJ.Ritter,andAlissaR.Segal  ManagementofInsulinPumpsinHospitalizedPatients 571 BithikaM.Thompson,PatriciaA.Mackey,andCurtissB.Cook  ManagementofDiabetesand/orHyperglycemiaduringEnteralandParenteral Nutrition 584 AidarR.GosmanovandNiyazR.Gosmanov  ManagementofDiabetesand/orHyperglycemiainHospitalizedPatientswith RenalInsufficiency 598 GlennMatfin  ManagementofGlucocorticoid-InducedDiabetesand/orHyperglycemia 616 HanNaKimandNestorasMathioudakis  ManagementofDiabetesand/orHyperglycemiainAcuteCoronarySyndrome, AcuteStroke,andAcuteHeartFailure 632 MilesFisher  AcuteDiabeticFoot 648 GlennMatfin PartX SodiumDisorders 673 Introduction:EmergencyManagementofSodiumDisorders 675 RichardH.Sterns Contents ix  EmergencyManagementofAcuteandChronicHyponatremia 679 JosephG.Verbalis  EmergencyManagementofAcuteandChronicHypernatremia 700 AoifeGarrahyandChristopherThompson PartXI ObesityandClinicalLipidology 717 Introduction:EmergencyManagementRelatedtoObesityand ClinicalLipidology 719 RobertH.Eckel  AcuteEmergenciesRelatedtoBariatricSurgery 723 MichaelA.ViaandJeffreyI.Mechanick  ChylomicronemiaSyndrome:VerySevereHypertriglyceridemiaand AcutePancreatitis 742 AnthonyS.Wierzbicki  Statin-RelatedMyopathyandRhabdomyolysis 760 ConnieB.NewmanandJonathanA.Tobert Index 775

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The Essential Guide to Recognizing and Treating Acute Endocrine and Metabolic Illness Endocrinology covers some of the most common conditions and serious public health challenges facing medicine today, and endocrine and metabolic emergencies constitute a large proportion of the clinical workload. En
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