Encyclopedia of Traditional Chinese Medicines - Molecular Structures, Pharmacological Activities, Natural Sources and Applications: Vol. 1: Isolated Compounds A-C

590 Pages·2011·7.08 MB·English

by  Jiaju Zhou

Encycloped ia of Traditional Chinese Medicines
Molecular Structures, Pharmacological Activities,
Natural Sources and Applications

Jia ju Zhou • Guirong Xie • Xinjian Yan

Encycloped ia of

Traditional Chinese Medicines

Molecular Structures, Pharmacological

Activities, Natural Sources and Applications

Vol. 1: Isolated Compounds A-C
Jiaju Zhou Guirong Xie Xinjian Yan
1303, Buld . 10, Apt-2-1-302, 523 Redlan d Blvd,
31 ZhongGuanCun NanDaJie, 43 NongDa NanLu, Rockville,
HaiDian District, BoYaXiYuan, MD 20850,
100081, Beijing, HaiDian District, USA
China 100193, Beijing, yunyan316 @yahoo.com
[email protected] China
[email protected]
ISBN978-3-642-16734-8 e-ISBN978-3-642-16735-5
DOI10.1007/978-3-642-16735-5
SpringerHeidelbergDordrechtLondonNewYork
LibraryofCongressControlNumber:2011922128
#Springer-VerlagBerlinHeidelberg2011
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Encyclopedia of Traditional Chinese Medicines
Molecular Structures, Pharmacological Activities, Natural Sources and Applications
Contents
Preface ........................................................................................................................... vii
Introduction .................................................................................................................. ix
How to Use This Book ............................................................................................... xix
Abbreviations and Symbols ....................................................................................... xxv
Cancer Cell Codes ..................................................................................................... xxix
Volume 1 Isolated Compounds (A-C)
A (entries 1~2071) ........................................................................................................... 3
B (entries 2072~2835) ................................................................................................ 241
C (entries 2836~4594) ................................................................................................ 327
Volume 2 Isolated Compounds (D-G)
D (entries 4595~6656) ..................................................................................................... 3
E (entries 6657~7700) ................................................................................................ 225
F (entries 7701~8043) ................................................................................................ 343
G (entries 8044~9185) ................................................................................................ 383
Volume 3 Isolated Compounds (H-M)
H (entries 9186~10927) ................................................................................................... 3
I (entries 10928~11806) ............................................................................................. 187
J (entries 11807~11990) ............................................................................................. 283
K (entries 11991~12399) ............................................................................................ 308
L (entries 12400~13280) ............................................................................................ 356
M (entries 13281~15227) ........................................................................................... 459
Volume 4 Isolated Compounds (N-S)
N (entries 15228~15880) ................................................................................................ 3
O (entries 15881~16484) ............................................................................................ 73
P (entries 16485~18281) ............................................................................................. 142
Q (entries 18282~18455) ............................................................................................ 350
R (entries 18456~19091) ............................................................................................ 375
S (entries 19092~20574) ............................................................................................. 453
v
vi
Volume 5 Isolated Compounds (T-Z)

T (entries 20575~22170) ................................................................................................. 3
U (entries 22171~22301) ............................................................................................ 184

V (entries 22302~22625) ............................................................................................ 201
W (entries 22626~22742) ........................................................................................... 238

X (entries 22743~22856) ............................................................................................ 254
Y (entries 22857~22960) ............................................................................................ 270

Z (entries 22961~23033) ............................................................................................ 284
References for Isolated Compounds ........................................................................... 293

TCM Plants and Congeners (entries T0001~ T6926) .................................................. 347

Volume 6 Indexes
Compound Pharmacological Activity Index .................................................................. 3

Compound Molecular Formula Index ........................................................................ 65
Compound Name Synonym Index .............................................................................. 285

TCM Plant English Name Index ................................................................................ 347
TCM Plant PIN-YIN/Chinese Name Index ................................................................ 458

TCM Plant Traditional Effect Index ........................................................................... 580
TCM Plant Traditional Indication Index .................................................................... 624
Preface

A significant preoccupation of modern traditional Chinese medicine (TCM)
research has been the characterization of TCM components, such as pertain to their
isolation, purification, structural determination, and pharmacological activity. As a
reference tool, this Encyclopedia of Traditional Chinese Medicines presents a
comprehensive and integrative work on surveying TCM plant sources, chemistry,
pharmacology and medicinal effects and indications in a systematic manner.
This encyclopedia is an integrated achievement of a long-term TCM research
project by the authors at the Chinese Academy of Sciences [1–4], involving three parts
and now organized in six volumes:
Part I (Volumes 1 to 4 and part of Volume 5) provides structural, physical,
pharmacological and natural source information on 23,033 isolated chemicals captured
from 5,535 references, basically up to year 2005. A great deal of effort has been paid on
overlapping or contradictory data in order to provide readers with an accurate and
reliable resource.
Part II (last part of Volume 5) describes 6,926 TCM plants and congeners, together
with their medicinal effects and indications. The contents of Part I and Part II are all
organized in alphabetical order.
Part III (Volume 6) includes seven indexes produced by a computer program.
Based on the indexes, users can readily find concerned contents in multiple ways.
With this encyclopedia, the authors attempt to provide a bridge for the
communication between the TCM system and Western medicinal systems, and a
platform with multiple-subjects in support of research and development of the health
sciences.
JJ Zhou, GR Xie and XJ Yan
Institute of Process Engineering, Chinese Academy of Sciences
Sep, 2010, Beijing
---------------------------
[1] Xinjian Yan, Jiaju Zhou and Guirong Xie, Traditional Chinese Medicines: Molecular structures, natural sources,
and applications, 1st edition, Ashgate Publishing house, 1999
[2] Jiaju Zhou, Guirong Xie and Xinjian Yan, Traditional Chinese Medicines: Molecular structures, natural sources,
and applications, 2nd edition, Ashgate Publishing house, 2002
[3] Jiaju Zhou, Guirong Xie and Xinjian Yan, Handbook of Chemical Components in Plant Origins of Traditional
Chinese Medicines, Chemical Industry Press, Beijing, 2004 (in Chinese)
[4] Jiaju Zhou, Guirong Xie and Xinjian Yan, Data Collection of Chemical Components in Plant Origins of
Traditional Chinese Medicines, Vol 1–3, Science Press, Beijing, 2009 (in Chinese)
vii

Introduction

This encyclopedia mainly consists two parts - compound and plant. Its core
content is the structural and pharmacological information of 23,033 phytochemicals, as
well as medical effects and indications of 6,926 plant species from which the
phytochemicals were isolated. The compounds, i.e. phytochemicals, are ordered
alphabetically, and their ordinal numbers are used as compound unique codes. The
plant species are coded from T0001 to T6926. With this code system, the complicated
“many to many” relationship between compounds and plants can be clearly expressed,
and any individual compound or plant could be located easily in this 6 volumes book.

1. Compound Entry

Format of Compound Entry. A compound entry starts with a title line, in which there
are two items: the compound’s unique code and main name. Following the title line is
the compound physical, pharmacological and source information, which may include 8
items:

Title line (code number, main name)
A. Synonyms of the compound (if any);
B. CASRN number (if any);
C. Formula (relative molecular mass);
D. Physicochemical properties;
E. Pharmacological data (if any);
F. Source(s);
G. Reference(s);
H. Graphic structure.

Chemical Names and Synonyms. Generally, a compound may have one scientific
name and several trivial names. In the encyclopedia, based on original articles, we
select one name as the “main name” (appeared at the title line of each compound entry),
and use it to alphabetically order the 23,033 compounds in the first 5 volumes. The
main name is either a scientific name or a trivial name. All of other names of each
compound, if any, are presented after the title line.

Stereochemistry of Chemical Structure. We protracted all compound structures down
to atom-bond level including complicated glycosides, with stereo-chemical information
based on the data in the original papers. For example, the structure with full
stereochemistry of compound 22,834 (isolated from CHUAN XU DUAN Dipsacus
asperoides) is:

ix