Encyclopedia of Pharmacology Research

726 Pages·2012·10.738 MB·English

by  Derek Cheng, George Liu

PHARMACOLOGY - RESEARCH, SAFETY TESTING AND REGULATION

E
NCYCLOPEDIA
P R
OF HARMACOLOGY ESEARCH
(2 V S )
OLUME ET

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P - R , S
HARMACOLOGY ESEARCH AFETY
T R
ESTING AND EGULATION

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PHARMACOLOGY - RESEARCH, SAFETY TESTING AND REGULATION

E
NCYCLOPEDIA
P R
OF HARMACOLOGY ESEARCH
(2 V S )
OLUME ET

DEREK CHENG
AND
GEORGE LIU
EDITORS

Nova Science Publishers, Inc.
New York
Copyright © 2012 by Nova Science Publishers, Inc.

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LCCN: 2010012146 and 2009001297
ISBN: (cid:28)(cid:26)(cid:27)(cid:16)(cid:20)(cid:16)(cid:25)(cid:20)(cid:23)(cid:26)(cid:19)(cid:16)(cid:23)(cid:19)(cid:24)(cid:16)(cid:27) (eBook)

Published by Nova Science Publishers, Inc. † New York
CONTENTS

Preface ix
Volume 1
Chapter 1 Neuroplasticity: A New Approach to Treatment of Depression 1
Tayfun Uzbay
Chapter 2 Antidepressant Therapy and the Risk of Suicide Among
Patients with Major Depressive Disorders 69
Maurizio Pompili, Gianluca Serafini, Marco Innamorati,
Michele Battuello, Mariantonietta Milelli,
Roberto Tatarelli and David Lester
Chapter 3 Monitoring of Antidepressant Therapy by Using
Heart Rate Variability 93
Sven Suefke, Hasib Djonlagic, and Thomas Kibbel
Chapter 4 The Overlap between Depression and Suicidal Behaviour:
Implication for the Preventative Effect
of Antidepressant Pharmacotherapy 117
Louise Brådvik and Mats Berglund
Chapter 5 Synthetic Inhibitors of Prolyl Endopeptidase
Exhibit Antidepressant-Like Effects in Rat Models
of Depressive Syndrome and Anxiety-Depression State 137
N.A. Krupina, N.N. Khlebnikova, N.N. Zolotov,
E.Yu Kushnareva, N.G. Bogdanova, and I.N. Orlova
Chapter 6 Beyond the Monoamine Hypothesis: The Quest for an Integrative
Etiology of Depression and New Therapeutic Strategies 157
Barbara Di Benedetto, Rainer Rupprecht,
and Gerhard Rammes
Chapter 7 Tianeptine and Sertraline: Underlying Neurochemical
Mechanisms of Action 171
Rustem Uzbekov and Irina Alieva
vi Contents
Chapter 8 Gender Differences in Response to Antidepressants 201
Shigeru Morishita, Toshihiko Kinoshita and Seizaburo Arita
Chapter 9 Adult Neurogenesis and Depression:
A Novel Theory for Depression? 223
Philippe Taupin
Chapter 10 Micro- and Nano-Particulate Drug Delivery Systems
for Cancer Treatment 227
José L. Arias
Chapter 11 Geldanamycin Derivatives as Promising Anticancer Drugs:
Therapy via Hsp90 Inhibition 309
Alexander E. Kabakov
Chapter 12 Synergistic Antitumor Activity of Metronomic Dosing
Chemotherapy in Combination with Liposomal Anticancer Drug 335
Tatsuhiro Ishida and Hiroshi Kiwada
Chapter 13 Organotin Polyethers as Anticancer Drugs 365
Charles E. Carraher, Michael R. Roner and Girish Barot
Volume 2
Chapter 14 Studies on Anti-Cancer Agents: Phenolic Compounds
and Their Pharmacological Activity 389
Maria Dolors Pujol and Isabel Sánchez
Chapter 15 Design of Novel Anticancer Drugs Utilizing Busulfan
for Optimizing Pharmacological Properties and Pattern
Recognition Techniques for Elucidation of Clinical Efficacy 413
Ronald Bartzatt
Chapter 16 Analysis of Associations among Novel Property Descriptors
and Their Capacity in Determining Clinical Efficacy
by Utilizing Pattern Recognition Techniques 429
Ronald Bartzatt
Chapter 17 Insights into the Mode of Action of Bioreductive
Ruthenium Cytotoxins 445
Erwin Reisner
Chapter 18 Marina Crystal Minerals (MCM) Induce Apoptosis of Human
Metastatic Breast Cancer MDA-MB-231 Cells in Vitro 457
Mamdooh Ghoneum, Takeshi Ogura and Sastry Gollapudi
Chapter 19 Bioequivalence: Some Relevant Clinical
and Biopharmaceutic Aspects 467
Francisco J. Flores-Murrieta, Miriam del C. Carrasco-Portugal,
Héctor León-Molina and Miguel Luján
Contents vii
Chapter 20 Advances in Drug Discovery to Assess
Cholinergic Neurotransmission 503
David R. da Rocha, Vitor F. Ferreira,
Kátia G. Lima Araújo and Wilson C. Santos
Chapter 21 Method Suitability for Models of Intestinal Drug Permeability 545
Donna A. Volpe
Chapter 22 Stevens-Johnson Syndrome with Ocular Complications 569
Mayumi Ueta
Chapter 23 Prophylactic Effect of Rescalmin, an Antiallergic Agent,
against Hypersensitivity Reactions to Anticancer Drugs:
Paclitaxel and Beyond 585
Shinji Sasada
Chapter 24 Pharmacopoeial Quality of Antimicrobial and Antiviral
Formulations from Former Soviet Union Republics:
Focus on Aciclovir 597
Andres Meos and Vallo Matto
Chapter 25 The Interaction of the Prion Protein with Triazine-Based
Biomimetic Affinity Ligands 607
Giannis Mavridis and Nikolaos E. Labrou
Chapter 26 Downstream Processing Strategies for the Purification
of Recombinant Proteins from Transgenic Maize.
Chromatographic Evaluation of the Synthetic Affinity
Ligand 4-Amino-Phenyl-Oxanilic Acid 619
Dimitris Platis and Nikolaos E. Labrou
Chapter 27 A Critical Approach to an Allergic Paradox: Allergic a
nd Allergic-Like Reactions to Glucocorticoids:
Delayed Hypersensitivity Mechanisms 639
M. T. Ventura, G. F. Calogiuri, R. Buquicchio,
R. A. Tummolo and M. Digregorio
Index 659