I PublibshyPe eda rson EdLuicmaittaie odcn,o mpianncyo rpoirEnan tgeldaa nndd Wales, haviintrgse gisteraeEtdd if.Jo;uf rfgGihac teeH ,a rloEws,s eCxM,2 02 JE. Regsiteredc ompannuym be8r7:2 828 I Edexciesal r egistetrreadmd aer okfE d excel Limited I Text©P earsEodnu cation L2i0m0it9e d Alpla setx amq uesti©o nEsd excel Ther ighotfsG arSyki nnre, RobiHna rbou(rEds sCeoxu ntyC ouncainlEd)d L eetsob e iednteidfa ist haeu thoofrt sh iwosr hka veb eena ssertbeytd heimna ccordwaintche teh Coyprig,hD tesigannsPd a teAncttos f1 988. 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Exterpnraolj emcatn agembeySn uteK earsey EditbeydL iJzo nes Typesbeyt3 20D esigLnt d IllustrbayOt xefdo rDde sig&n Ielrlsu strators Coveprh ot©o JupiUtneilmrti de PrintienMd a lays(iCaT P-VVP) Acknowledgements Edexcreelv iebwyM artFiunr nemsist-UhSY,SE Gr evieAwn nbSeyc ott We woulldit koet haDnakm iRaind dlAnen,e S coatntEd l izaSbweitnhb afnotkrh eir contributions Disclaimer Thimsa terhiabasle epnu blishbeedh aoolfEnf d exacnedol f fheirgsh -qsuuaplpiotryt fotrh dee liovfEe dreyx qcueall ifications. Thisd oenso tm eant hatthm ea etraili se ssenttioaa clh ieavneyE dexqcuelalfiic ation, nord oesi mte ant haitt i tsh oen lsyu itambaltee raivaali latbols eu ppaonryEt d excel qualificEadteixocnme.al t erwiiallnl o tb eu sedv erbatiinsm e tting anyE dexcel examinatoirao sns essmeAnntyr. e sourlciesp trso ducbeydE dexschealiln cll utdhei s ando thearp rpopriatree sources. Copieosfo ffiscpieacli fifcoaarltE lid oexncsqeu la lificmaatyib onefs o uonndt he Edexcweelb iste: www.edexcel.com J Revisitoenc hniques 4 Theh earetn.e rgayn de xercise so Homeostasis 52 How tou set hiRse visiGouni de 5 Healtehx,e rcainsdes port 54 Questiotny peisn G CEB iology 6 Topi7c c hecklist 56 Uni4t: ThNea turEanlv ironmeanntd S pecies ResultsBPuliulBsde: t tAenrs wers 57 Practqiucees tions 58 Survailv Topi5c: O n thew ilsdi de 8 Topi8c: G reym atter 60 Photosynth1e sis 8 Respondtiont gh ee nvironment 60 Photosynt2h esis 10 Neuronaensd n erviem pulses 62 Energtyr ansafbeurn,d anacnedd istributi1o2 n Vision 65 Investignautmibnegra sn dd istribution1 4 Thes tructouftr hee h umanb rain 66 Speciatainoden v olution 16 Braidne velopment 67 Greenhoguassee asn dt hec arbocny cle 18 Learnianngdh abituation 69 Impacotfsg lobwaalr ming 20 Effeocfti sm balanicnbe rsa icnh emicals 70 Topi5c c hecklist 22 Useosf g enetmiocd ification 72 ResultsBPuliulBsde: t tAenrs wers 23 Topi8c c hecklist 74 Practqiucees tions 24 ResultsBPuliulBsde: t tAenrs wers 75 Practqiucees tions 76 Topi6c: I nfectiiomnm,u nitayn df orensics 26 Uni5t s pecimpeanp er 78 Decaayn dd ecomposition 26 Uni5t comprehenpsriaocnt ice 82 DNA profiling 28 DNA andp rotesyinnt hess i 30 Unit6: P ractBiicoallao ngdyI n vestigaSktililvse8 4 Infectious adnidts heeai smemsu ner espons3e2 Gettisntga rtweidt h yionuvre stigation84 Infection, parnedcv eonnttiroonl 34 Planning 85 Topi6c c hecklist 36 Plannintgr-iianlv estigations 86 ResultsBPuliulBsde: t tAenrs wers 37 Observianngdr ecording 87 Practqiucees tions 38 Dealiwnigt dha ta 88 Uni4t s pecimpeanp er 40 Interpraentdie nvga luating 89 Answertso i n-teqxute stions 90 Unit5 :E xerciasned C oordination Answertso p ractiqcuee stions 95 Topi7c: R unf ory ourl ife 44 Answertso s pecimepna peqru estions 99 Musclaensd m ovement 44 l Energayn dt her oloe=A TPi nr espiration4 6 Index 102 Krebcsy claen dt hee lecttrroann spcohrati n 48 L l Il l l Gettisntga rtceadnb et heh ardepsatr otf r evisiond,o nb'ltue ta viett ool atRee.v ise litatnldeo fteIDn o n'stp entdo ol ogn ona nyo nes ectibountr, e viistsi etv ertailm es, andi ft heriess omethiynogud on'utn derstaansdky, o utre achfeorhr e lp. Jusrte aditnhgr ouygohu nro teissn ote nougTha.k aen a ctiavpep roaucshi nsgo meo f ther evistieocnh niqsuuegsg estbeedl ow. I Active � workbse swth en Tesyto urself Make sured oyno'eutn du pj uscto pyionugty ounro teisnf ulUls.es omeo ft hese techniqtuope rso duccoen densneodt es. • Tablaensd l isttops r eseinntf ormactoinocni sely • Indecxa rdtsor ecotrhde m osti mportpaonitn ftoser a chs ection • Flocwh arttosi dentsitfeypi sna process • Diga1a mst op reseinfnotr mativoins ually • Spiddeira grammisn,d m apsa ndc oncempatp st os howt hel inbkest weeind eas • Mnemonitcosh eiyro ur emembelri sts • Glossatroim eask es uryeo uk nowc leadre finitoifko enyst erms Inclupdaeg er eferentcoye osu nro teosr t extboUoske.c oloaunrd h gihlighgt tiopn ick outk eyt erms. Usinag v arioefta yp proacwhielspl r eveynotu rre visbieocno -nibnogr inagn dw ill Chectkh esp ec. makem oreo ft hei deasst icHke.r aer es omem ethodtsot ry. Ify ouu ser esourfcreosm • Explain ideatsoa partnearn da sk each qoutehsetri ons. elsewhemraek,es urteh ecyo ver • Makea podcaasntd p laiytb actk oy ourself. ther igchotn teanttt h er iglhetv el. • UseP owerPotionm ta kei nteracntoitveaesn dt ests. • Searcthh ei nterfnoerat n imatitoenssat,ns d t utortihaalytso uc anu se • Worki na groutpo c reaatned u seg amesa ndq uizzes. Oncey ouh aver evisae tdo piyco,un eedt oc hectkh ayto uc anr emembaenrd a pply whaty ouh avel earnt. • Uset heq uestifornosmy outre xtboaonkdt hirse visgiuoind e. • Gets omeonteo t esyto uo nk eyp oints. • Trys omep asetx amq uestions. Welcomteo y ouErd excAe2l BiologRye visiGouni dep,e rfewchte theyro u're studyiSnagl teNrusf fiAedlvda ncBeid olo(gtyho er angbeo oko)r,t he' concept-led' approatcohE dexcBeilo lo(gtyhg er eebno ok). Thiusn iqugeu idper ovidyeosuw ittha ilosruepdp orwtr,i ttbeyns enoire xaminers. Theyd rawo nr ea'lR esultsePxiaumds a't far opma sAt- leveexla msa,n dh aveu setdh is toi dentciofmym onp ifatlslt hahta vec aughotu to thesrt udenatnsda, r eaosn w hich tof ocuyso urre visAisoy no.u w orky ouwra yt hroutghhe t opiclso,oo ku tf otrh e followfienagt utrherso ughtohuett e xt. ResultsPElxuasm ineTri'ps Thessee ctihoenlsyp o up erformt oy oubre sitn t hee xamb yh ighlighkteiyn g termasn di nformatainoanl,y stihneqg u estiyoonusm ayb ea skeadn,d s howing howt oa pproaacnhs weritnhge mA.l olf t hiissb aseodn d atfar omre al-lei fA-level students! Resul"i:WsaPtichuO sut Thee xaminehrasv leo okebda cakt d atfar omp revieoxuasm tso f intdh ec ommon pitfaalnldms i stakmeasd eb ys tudentasn-dg uidey ouo nh owt oa voirde peating themin y ouerx am. QuicQku estions Uset hesqeu estiaosna s q uicrke catpot esyto ukrn owledagsey oup rogress. Thinking Task Thessee ctions pfruorvtihrdeeersa ercho ra nalysist otd aesvkesly oopu r understanadnidnh gel ypo ur evise. WorkedE xample Thee xaminegrusi dyeo ut hroucgohm pleexq uatiaonndsc oncepptrso,v idsitnegp by-stgeupi danocneh owt ot ackelxea mq uestions. Eacth opiacl seon dsw ith: -;-opiCch ecklist Thissu mmariwsheast y ous houlkdn owf otrh itso piwch,i cshp ecificpaotiinotn eachc heckpocionvte arnsd w herien t heg uidyeo uc anr eviisteU.s ei tt or ecord youprr ogreassys o ur evise. I ResultsPBiuuislB de tter Answers Heryeo uw ilfli nsda mpleex amq uestiwointseh x emplaanrs weresx,a minteirp s anda c ommentacroym paribnogt ah basiacn da ne xcellent rseos ypooucn asne ; I seeh owt og ett heh ighemsatr ks. :,�actiQcuee stions Exam-stqyulees tioinnsc,l udmiunlgt iple-cohfofiepcrle e,n otfyp ractaihceea odf I thee xam. BotUhn i4t a ndU ni5t c oncluwdiet ah S pecimePna petro t esyto ulre arniTnhge.s e I aren oti ntendaestd i mefdu,l l-lengthb uptpa rpoevrisad, re a ngoef e xam-style practqiucees ticoonvse ritnhger angoef c ontelnitk etloby e e ncountered within thee xam. I Thef inuanli cto nsiosfta sd viacned s uppoorntr esearsckihl glisv,i gnugi danocne PractiAcssaels smteonh te lypo uw ritbee ttienrd iviidnuvaels tigations. Answertsoa ltlh ei n-tqeuxets tioasnw se,ll a sd etailmeadrk,- by-marakn swetrost he I specimen pcaapneb resf ,o unadt t heb acko ft heb ook. We hopey ouf intdh igsu idien valuaBbelseot.f l ucIk I I ..._ Multiplceh o�ce A goomdu lticphloeiq cuee stgiiovnye osut hceo rraencstw aenrdo thpeors sible answewrhsi cshe epml ausible. Triglycaerrceio dmepso soefd: (1 ) D 3 glycmeorloelc ualn3ed fs a tatcyim do lecules D 1 glycmeorloelc aunl3de f atatcyim do lecules D 1 glycmeorloelc aunl1def atatcyim do lecule D 3 glycmeorloelc aunl1ed s f atatcyim do lecule Thbee swta yt oa nswaem ru lticphloeiq cuee stiitso orn e atdh qeu estainodtn r y toa nswiebtre folroeoi knc:gtt hpeo ssiabnlsew eIrftsh .ae n swyeorut hougohfit s amongtshtpe o ssiabnlsew ejrosbd- onJeu!s hta vael ooaktt hoet hpeors sibtiol ities convince tyhoayutor uws eerlrefi ght. Ift haen swyeorut hougohfit s nt'hte rleo,oa ktt hpeo ssiabnlsew earnsdt rtyo elimiwnraotnaegn sweurnsty iolua rlee wfitt thh ceo rroencet. Youd on'ta lnomysa er kbsyh aviang gu e(sfisy ouc anw'otr oku tth aen swer) remembyeoruw on'stc oarney thbiyln ega vtihnaegn swbelra nIkfy! o un arrdooww n thneu mbeofrp ossiabnlsew etrhsce,h ancofeh sa vianl gu ycg kueastst hrei ght answweiril nlc rease. Toi nditcahcteoe r raencstw peurat,c roisnts h beo fxo llowtihcneog r rsetcatt ement. Ify ocu hanygoeu mri ndpu,at l itnher outghcher oasnsfd i ilnyl o unre wa nswweirt h ac ross. How Sccence Works Thei debae hiHnodw SicenWcoer kisst og ivyeo ui nsiignhtttoh wea yisnw hich scienwtoirskht:os wa ne xperiimdsee nsti ghnoewdt ,h eorainedms o dealrspe u t togethhoewrd ,a taar aen alyhsoewds ,c ienrteissptotsnof d a ctsourcashs e thiacnsd, soo na,n dt hwea ys ociieistn yv olivnme adk idnegc isaiboonusstc ience. Manyof t hHeS W critaerrpeir aa ctaincdwa ilbl el teasspt aerdot fy ouprr actical worHko.w evtehre,wr iebl elq uestioontn hswe r itutneipnta petrhsac to vseorm e HSW criteSmroeioa f.t heqsuee isotnwsi ilnlv odlavteoa rg rapihn terpr(eHtWSa tion 5)-seteh nee xste ction. Theo thceorm motny poefH S Wq uestwiioblnelb aseodnt hceo rper actQiuceasltsi.o ns wicloln cenntorstao tm eu cohn w hayto ud idb,uw th yv arisotuesip nts h ceo re practwiecriaeml p ortIatin'mtsp. o rttahnetr,e tfhoaryteo ,ku onww hatth vea risotuesp s ine accho rper actwiecrdaeel s igtnode oda; n dt hayto ur evtihsceeo rper acticals. Fore xamptlhei,an bko utthq eu estitohnacsto ubleda skeidnU nai 2t p apeornt he corper actiinTc oap3li: 'c D esctrhisebt ea goefms i toasnidhs o wt op repaanrdes tain ar oottis pqu asihno rder tot ::lhbepsmre arcvtei Hcearlesl,uy i.t'qa ubelset icoonusl d include: -whyd ow eu soen ltyh tei opft hreo ot? -whicsht adionw eu se? -whyd ow ep latchece u t itnai cpib dfe orset aining? -whasta feptrye ciaounwtsc ulbder elevhaenraten ,dw hy? You'alllsc oo mmongleyat s kqeude stiionnvso ldveisnigg annii nngv estitghaetsieo n: arlei kteoil nyv opliveeco effs a miplriaacrt wiocrakTl.h C eO RMS prommpaty b e usfeuhle re: Control- Arey oui nvestigsaitmipnwlgiy t Ihw ithoau pta rticfualcatro r? What raonfgv ea luaersey oul ookiantgl Organis-mA rey ouu sinogr ganisofmt sh es ames exIa ge1 s izIes pecies? Repeat -Taker eadinmgosr et haonn cea nda verage Measure- Whata rey oum easuriHnogw?w ilylo um easurteh isW?h atu nits? Same -Whichv ariabalreey( so)uk eepicnogn stant? OtheHrS W questimoanysc oncentornaet teh iicsals useusr roundtionpgis cusc ahs genet heraopryG M foods. enterpretaotfog orna phs Theg rapbhe loswh owtsh er esuolfta s s urvienyA mericoan,t hei ncideonfch ee art diseaisnae d ulatgse d1 8a ndo lder. Usintgh ei nformaitnit ohneg raphd,e scrhiobwet he1 ncideonfch ee ardti seaisse affecbtyea dg ea ndg ender. (3) soo � 400 � § :.0� -3g_�0 0 Key Cl! .Co_0 D female (5o D Cl! g zoo male �� "0Cl! Cl!� ·u a.. c 100 18-44 4S-64 6S-74 7Sa ndo ver Youa lmosatl waygse to nem arkf osrt atitnhgeg enertarle -ndint hicsa steh atth e incideonfch ee arrta tien creawsietsih,n creaasgienf,go bro tghe nderYso.uc ant hen concentornai tned iviadsupaelco tfts h ed ataI.nt hicsa sew,h ats tanodust m osti st hat 18-44 femalheasv ael oweirn cideonfch ee ardti seatshea mna leesx,c eipntt he age group. mYaoyau l scoo mmentth atth ed ifferbeentcwee etnh ei ncideinnmc ael easn d 65-74 femaliesls a rgeisnt the ageg roup. Finaltlhye,ri esa lwayosn em ark fmoarn ipulaotfid oant aN.o tet hatth imsu st I bem anipul-aytoiudo onn 'gte tm arkfso rre adionfgtf h eg rapahn ds tatitnhge numberyso,u h aveto d os omethiwnigt thh em! I fE�tend�qdu estions 5) Int heA 2 unit(sT op4iac n dT opic youw ilclo mea croqsuse stiwointslh a rger 7 I numberosfm arksp,e rhauppst o6 or markisn t heq uestion. Questiionnts h esuen itasr ed esignteobd e s ynoptiicno- thewro rdst,h eayr e designfeodyr o ut os howk nowledggaei neidne arluineirt Bse.a trh iisnm indw hen youa nswetrh eq uestitornty:o i nclurdeel evkannotw ledfgreo my ouArS c ourse when answering qtuheesstei ons. 6 Remembetro,o t,h aitft heq uestiioswn o rthm arksy,o un eedt om akes ix creditwoprotihnytT sh.i nakb outth ep ointthsa yto uw ilmla kea ndp utt hemt ogether ina logisceaqlu enwchee ny ouw rityeo uarn sweOrn. l ongqeure st1otnhsee, x aminers wilble l ookiantyg o uQrW C (QualoiftW yr ittCeonm municataisow ne)la ls t he answeyro ug 1ve. Uni4t :T heN aturEanlv ironamnednS tpe ciesS urvival Photosynthiensviosl tvheers ,. d.e.uctioonfc arbodni oxi(d�C 0to2lc a rbohydrate_ ener Thescea rbohydrcaatnbe esu sedt op rovide gyi nr espira(tsieToeonp r7c )T.he _5t�.c;,. - hydrogfeontr h ipsr ocecsosm efsr omt hesp lttiigno fw atebry l ightth,ew aset oxygen o"'� beinrge leaisnetdtoh e a tmosphere. • P s.r Thicsa nb es ummariseldi kteh is: • €)-c ewe"' .., c"-<.V> I .tnr, t.- ZH20 frtohmes oil 1\ 4H 02 ; co,f <O<mh" •m "Ph'D"ia grasmh owintgh em ains tepisnp hotosyntLhiegshietsn .e rgsyp lits strobnogn disn w atetro g ivhey drogaennd o xygen( whicihsr eleased tot hea rmospheTrhee)h _y drogiessn t orienda fue(lg lucobsye ) Z('.:H20) reducincga rbodni oxitdoec arbohydrate. Ify ouim agine thea bovhea ppeningt hretei meyso,u h aveC 6H120wh6i,c ihsg lucose (anad n umbeorf o thesru garsse,eT opi1c. A1S ). Sot,h eo veraelqlu atiiosn: Thes plitotfiw nagt ebry l igihsct a llpehdo tolysThiese .n ergfyo rt hisst eipsf ir st trappbeyda pigmenmto lecuclael lcehdl orophyll. Theo verparlolc eissas c hievientd w ol inksetda gceasl ltehdel ight-dependent reactiaonndst hel ight-indepernedaecntti ons. reducNeAd DP light-dependent lig-hitndependent reactions reactions InT opi7c,R unf oyro ulri fyeo,uw ill meeta v ersyi milsaurb stantcoe NAOPc,a llNeAdD .I tt ooa ccepts Summaryo fp hotosyntshheoswiisnt gh el inklieghdt -dependenrte acti(oinwnsh icwha teirss plit electrbountts r nyo tm ixu pt het wo. andA TPa ndr educNeAdD Pa rem ade)a.n dt hel ight-indepreenadcetni(toi nwnsh icthh ee nergy froAmT Pa ndr educipnogw efrr omr educNeAdD Pa reu setdo m akes ugar). GreeBno ok5 .1O rangBeo ok5 .2 Topic t5h:we i Olsndi de Thel ighdte=pende�rte ac\iiob"llS Int hipsr oceas psa,i orf e lectrfornosmc hlroophyilsbl o ostteoda higheenr erglye vel _::/:_ -.� Results"Pius : byt hel igehnte rgiyth ast rappeHde.r teh eayr ea cceptbeyda ne lectarcocne ptor � Examiner andt hepna sseadl onag c h�:onfc arriEenresr.gr ye leaisseu ds etdo c onveArDtP ""� \ .·. ' tip · andi norgapnhiocs pha(tPeii )n tAoT PT hipsr oceisscs a llpehdo tophosphorylation Youw ilnlo tb ee xpectteord e call (thlei ght-dardidvietnio fop nh osphaTthee)e lectrtohnesen n tearn othcehrl orophyll detaoiflp sh otosystbeumtys o u molecuTlhee.e lectreovnesn tuapalsltsyo N ADPw itthh eh ydrogferno mw ater mayb ee xpecteudn dteor stand tof ormr educNeAdD PT.h eA TPa ndr educNeAdD Pa ret heuns eidn t hel ight theriorl eistf h eayr ep arotfa n independreenatc titoomn ask ec arbohydfrraotmce a rbodni oxide. examq uestion. Key -"'�f loowf e lectrionnn so n-cyclic photophosphorylation -y. floowf e lectrioncn ysc lpihco tophosphorylation chaionfse lectrcoanr riers ·· .�- ,..- ResultSP"ius �- Examin. teirp · :.· -.,..::., � • � •: ' ,j • Nevetrr tyo a nswear q uestiwoint l jusatd iagraaml,w ayisn clusdaem explanaotfiw ohna its g oinogn . NADP + 2H+ J f Q1T hed iagrsahmo wtsh ere sults reduced ofa ne xperimienwn hti cahi r NADP contaiinsiontgo 1p8e0sa2 n d watecro ntainHi2n1g6w 0a s increasing bubbltehdr ouag hs uspension energy light ofa lgae. level Diagrasmh owinlgi ght-depernedaecntti oPnhso.t osystPeSmIas n dP SIa/r et het wos pecicahll orophyll dark tight dark moleculwehsi cchan r eleatshee ierl ectwrhoennss t rubcykl ight. Concentration of oxygen isototnp e L thew ater Q1 Namet hes ubstawnhciec phr ovirdeedsu cipnogw e(re lcetrso)na nd "o, theo new hicshu ppleineesr gfyo trh el ight-indepreenadcetniotof n s 10 20 304 0 50 Time/min photosynthesis. Q2 Whati s: Sayh owt hesdea tsau ppotrhtei de a reduction thatth eo xygegni veonf bfy p lanit s b oxidat7i on photosyntchoemseifssr owma ter. GreeBno o5k. 1O rangBeo ok 5.2