s«*v.C£$.^ Economics of Reproductive and An Infant Health: Annotated From Bibliography 1980 to 1993 December 1995 I U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service Centers for Disease Control and Prevention CENTERASNFDORPRDEIVSEENATSIEOCNONTROL National Center for Chronic Disease Prevention and Health Promotion Division ofReproductive Health . . This publication was developed and produced by the National Center for Chronic Disease Prevention and Health Promotion of the Centers for Disease Control and Prevention. National Center for Chronic Disease Prevention and Health Promotion James S. Marks, M.D., M.P.H. . Director Virginia S. Bales, M.P.H. Deputy Director Technical Information and Editorial Services Branch Christine S. Fralish, M.L.I.S. Chief Gail A. Cruse, M.L.I.S. Technical Information Specialist Division of Reproductive Health E. Thomas Starcher, III Acting Director Lynne S. Wilcox, M.D., M.P.H. Deputy Chief, Program Services and Development Branch Suggested Citation Centers for Disease Control and Prevention. Economics ofReproductive and Infant Health: An Annotated Bibliography From 1980 to 1993. Atlanta, Georgia: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, 1995. This publication was prepared by Aspen Systems Corporation under Contract No. 200-92-0526 for the National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services. Contents should not be construed as the official policy of the National Center for Chronic Disease Prevention and Health Promotion or any agency of the federal government. f^tiOfcp^&l Economics of Reproductive and An Infant Health: Annotated From Bibliography 1980 to 1993 December 1995 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service Centers for Disease Control and Prevention National Center for Chronic Disease Prevention and Health Promotion Division ofReproductive Health Economics of Reproductive and Infant Health: An Annotated Bibliography From 1980 to 1993 December 1995 Table of Contents Preface iii How to Use This Publication v 1. Infant and Child Health Preterm Birth and Neonatal Care 1 General Infant and Child Health 25 References 41 2. Birth Defects, Mental Retardation, and Chronic Conditions Prenatal Screening for Infant Conditions 47 Infant Screening 61 Mental Retardation, Down's Syndrome, and Developmental Disability 73 Genetic Disorders and Chronic Conditions 83 References 93 3. Maternal Health Services Delivery 99 Screening for Maternal Infections and Conditions 109 Alcohol, Tobacco, and Drug Use 129 Adolescent Pregnancy 135 Cesarean Section 143 Preterm Labor, Placenta Previa, and Cerclage 153 Economics and Prenatal Care 161 References 171 4. Family Planning and Women's Reproductive Health 179 References 193 5. Nutrition 199 References 205 6. International Health 207 References 219 7. Methods 223 References 249 INDEXES Title Index 257 Author Index 271 Subject Index 287 Preface For the foreseeable future, public health professionals can expect fiscal concerns to heavily influence health and prevention policies. Without a thorough understanding of the costs and the impact of health services, we run the risk of losing resources to provide these services. No matter how compelling the arguments of need, equity, or compassion are, policymakers will need evidence of economic efficiency to accompany information on health improvement. Without such cost-related data, those of us who advocate for the health and well-being of women and children will be diminished in our effectiveness. To address this need, the Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, has assembled relevant literature on economic issues in reproductive health. This annotated bibliography covers published reports from 1980 to 1993 and includes 266 abstracted articles and 238 additional references. It addresses a wide range of concerns in women's and children's health and presents studies on cost-benefit, cost-effectiveness, cost utility, and other economic analyses. Along with studies of specific conditions, it includes articles related to methodology in economic analysis that will aid us all in becoming more informed users of economic reports. Although our literature search may not have identified all relevant material, we believe that this bibliography provides useful information on the state of knowledge in this field as it relates to reproductive health. A review of the articles presented in this bibliography indicates that much information is already available on the economics of women's and children's health. For example, some topics, such as neonatal intensive care and birth defects screening services, have received extensive attention and analyses. But many gaps still exist. Pediatric passive smoke exposure, for example, is only beginning to be examined from an economic perspective. We hope that this bibliography will aid in highlighting both the depth and the gaps in our current knowledge and will prepare us to make use of what is known and to investigate what remains to be learned. Readers are cautioned to examine these studies with care because the methods of analysis are not yet standardized—papers with different findings may represent quite different approaches to the issue under investigation. The challenges facing researchers who study the economic health issues concerning women and children include defining the measurements of costs, identifying the services whose costs will be assessed, and defining the duration over which outcomes will be measured. Variations in definitions for each of these variables can produce different conclusions. As public health workers have always known, we must also recognize that decisions regarding the best use of public resources are not based solely on economic concerns. The most sophisticated techniques of cost measurement cannot describe all the benefits and disadvantages of a specific health program. Furthermore, such decisions must take into account the public's will to act on a health problem even if money is not saved or an intervention is costly. Economic analyses may usefully inform these decisions but are unlikely to provide the complete answer to the question, "Is this health service appropriate?" Even if some highly regarded preventive interventions are found costly for a given impact, such analysis can point researchers toward finding more efficient and less costly approaches. in We hope public health professionals in both practice and academia, clinicians, insurers, and others concerned with the health of women and children will find this a useful compilation. As advocates, we need to give decision makers the factual basis upon which to decide with confidence that fiscal prudence, along with altruistic concern, favors a woman- and child-oriented approach to health care. IV How to Use This Publication Arrangement ofItems Items in this publication are arranged in seven sections: (1) Infant and Child Health; (2) Birth Defects, Mental Retardation, and Chronic Conditions; (3) Maternal Health; (4) Family Planning and Women's Reproductive Health; (5) Nutrition; (6) International Health; and (7) Methods. The sections are divided into several parts. Items in each part are listed in alphabetical order by author. The items are numbered sequentially, beginning with 001. Space considerations did not allow for abstracting of every item we chose to include in this publication. The nonabstracted items are contained in the Reference Lists at the end of their relevant section and are denoted with an "R" before their sequential number. Indexes This publication contains three indexes. The Title Index lists document titles. The Author Index lists personal and corporate authors. The Subject Index lists selected key words describing the content of publications. If you know the title of a publication, use the Title Index. If you are looking for a publication produced by a particular person or agency, use the Author Index. If you want to identify items in a specific subject area, such as smoking education programs, use the Subject Index. Data Elements A citation and abstract are listed for each item in this publication. Data elements include the item number, title, form, author or corporate author, source, and abstract. Sample Description: Item Number 109 Title Costs and Benefits of Screening for PKU in Wisconsin. Form Journal article. Author Barden, H.S.; Kessel, R.; Schuett, V.E. Source Social Biology 31(1-2):1-17, Spring-Summer 1984. . Abstract Researchers conducted a comprehensive cost-benefit analysis ofa screening program to detect newborns with phenylketonuria (PKU) in Wisconsin. Classic PKU is a genetic disorder which, if undetected and untreated during the first few weeks of life, generally results in mental retardation and a variety ofother abnormal conditions. Researchers compared monetary costs ofthe detection and treatment program with the projected benefits (avoided costs) that result from the prevention ofthe mental retardation associated with the disorder. Investigators determined future costs and benefits using a 4 percent, 7 percent, and 10 percent rate of discount to achieve comparability between the present and future costs. The estimated costs ofthe State Laboratory of Hygiene for PKU testing for 1 year were $104,740 for 78,050 samples. Actual costs ofcollecting a blood specimen for testing were estimated at $4.60 per collection. Treatment costs for PKU for a 20-year period (discounted at 7 percent) were estimated at $40,830. Net benefits (benefits minus costs) for detecting and treating one person with PKU were $208,000 ($292,000 minus $84,000) using the 7 percent rate ofdiscount. Net benefits for detecting four persons with PKU per year in Wisconsin totaled $832,000, a large rate of return on a relatively small investment. 10 tables, 42 references. Obtaining Additional Information Questions about this publication may be directed to: Division of Reproductive Health National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention 4770 Buford Hwy, NE, Mailstop K-22 Attn: Lynne S. Wilcox, MD, MPH Atlanta, Georgia 30341-3724 (770) 488-5227 VI