ECG Masters’ Collection F E a v C o r G i Favorite ECGs from Master Teachers Around the World t e M E ECG Masters’ Editors: C G a Mohammad Shenasa, MD • Mark E. Josephson, MD • N. A. Mark Estes III, MD s s Ezra A. Amsterdam, MD • Melvin Scheinman, MD f r t o e m r Collection 230 exceptional electrocardiogram case studies curated from the libraries of 60 M s internationally recognized master teachers of ECG interpretation are brought together a ’ in this one-of-a-kind resource for student and teacher alike. s C t e Organized by disease type, ECG case studies are presented in a clinical context fol- r o lowed by questions and discussion. Medical students, residents, fellows, physicians T e l l Favorite ECGs from — anyone who is involved in caring for patients with various cardiovascular diseases a e c and other systemic pathologies — will find this unique collection with a global h c e perspective useful and practical in developing the skills necessary to reading ECGs. t Master Teachers r s i o A Key Topics r n Around the World o u n Conduction Disturbances: Sinus Node Disease/Sick Sinus Syndrome, AV Conduction n d Disturbances, AV Blocks, Bundle Branch Blocks, and Fascicular Blocks t n Miscellaneous Phenomena: Concealed Conduction, Superabnormalities, Aberrancy h e Editors: Conduction, Premature Atrial and Ventricular Contractions (PACs and PVCs) W n Preexcitation Syndromes o Mohammad Shenasa r n Early Repolarization l d n Long and Short QT Syndromes Mark E. Josephson n Brugada Syndrome N. A. Mark Estes III n Narrow QRS Complex Arrhythmias n Wide Complex Arrhythmias Ezra A. Amsterdam n Ischemia and Infarction Shenasa n Electrolyte Disturbances, Pharmacological and Recreational Agents Melvin Scheinman Josephson n Paced Rhythms and Device Troubleshooting Estes n Heart Failure, LVH, and Cardiomyopathies Amsterdam n Congenital Heart Diseases Scheinman n Special Considerations: Age, Race, Gender, and Athletes Forewords by n Syncope and ECG Troubleshooting Francis E. Marchlinski and Samuel Lévy This book includes a free digital edition for use by the first buyer. 3405 W. 44th Street For additional information regarding Minneapolis, Minnesota 55410 personal or institutional use, please www.cardiotextpublishing.com visit www.cardiotextpublishing.com. +1 (612) 925-2053 ECG Masters’ Collection Favorite ECGs from Master Teachers Around the World Mohammad Shenasa, MD Mark E. Josephson, MD N. A. Mark Estes III, MD Ezra A. Amsterdam, MD Melvin Scheinman, MD Minneapolis, Minnesota © 2017 Mohammad Shenasa, Mark E. Josephson, N. A. Mark Estes III, Ezra A. Amsterdam, Melvin Scheinman Cardiotext Publishing, LLC 3405 W. 44th Street Minneapolis, Minnesota 55410 USA www.cardiotextpublishing.com Any updates to this book may be found at: www.cardiotextpublishing.com/ecg-masters-collection Comments, inquiries, and requests for bulk sales can be directed to the publisher at: [email protected]. All rights reserved. No part of this book may be reproduced in any form or by any means without the prior permission of the publisher. All trademarks, service marks, and trade names used herein are the property of their respective owners and are used only to identify the products or services of those owners. This book is intended for educational purposes and to further general scientific and medical knowledge, research, and understanding of the conditions and associated treatments discussed herein. This book is not intended to serve as and should not be relied upon as recommending or promoting any specific diagnosis or method of treatment for a particular condition or a particular patient. It is the reader’s responsibility to determine the proper steps for diagnosis and the proper course of treatment for any condition or patient, including suitable and appropriate tests, medications or medical devices to be used for or in conjunction with any diagnosis or treatment. Due to ongoing research, discoveries, modifications to medicines, equipment and devices, and changes in government regulations, the information contained in this book may not reflect the latest standards, developments, guidelines, regulations, products or devices in the field. Readers are responsible for keeping up to date with the latest developments and are urged to review the latest instructions and warnings for any medicine, equipment or medical device. Readers should consult with a specialist or contact the vendor of any medicine or medical device where appropriate. Except for the publisher’s website associated with this work, the publisher is not affiliated with and does not sponsor or endorse any websites, organizations or other sources of information referred to herein. The publisher and the authors specifically disclaim any damage, liability, or loss incurred, directly or indirectly, from the use or application of any of the contents of this book. Unless otherwise stated, all figures and tables in this book are used courtesy of the authors. Library of Congress Control Number: 2017937042 ISBN: 978-1-942909-08-8 eISBN: 978-1-942909-18-7 Printed in The United States of America Dedication We dedicate this book in memory of Mark E. Josephson, MD (January 27, 1943 – January 11, 2017), who inspired and mentored many of us. He gave the electrogram a new look - “ECG as a mapping tool.” He is also the senior editor on this book. Contents Contributors ...........................................................................................................................vii Forewords ...............................................................................................................................xv Dr. Francis Marchlinski Dr. Samuel Lévy Preface ...................................................................................................................................xix Abbreviations ........................................................................................................................xxi Video Legends .....................................................................................................................xxiii Section 1 Introduction to the Interpretation of the Electrocardiogram ...........................1 Section 2 Conduction Disturbances: Sinus Node Disease/Sick Sinus Syndrome, AV Conduction Disturbances, AV Blocks, Bundle Branch Blocks, and Fascicular Blocks ...................................................................................................3 Section 3 Miscellaneous Phenomena: Concealed Conduction, Superabnormalities, Aberrancy Conduction, Premature Atrial and Ventricular Contractions (PACs and PVCs) ............................................................................41 Section 4 Preexcitation Syndromes ...................................................................................77 Section 5 Early Repolarization (ECG Pattern and the Syndrome) ..................................135 Section 6 Long and Short QT Syndromes ........................................................................153 A. Long QT Syndrome .....................................................................................153 B. Short QT Syndrome ....................................................................................173 C. Torsades de Pointes ....................................................................................175 D. Other Proarrhythmias .................................................................................193 Section 7 Brugada Syndrome ...........................................................................................197 Section 8 Narrow QRS Complex Arrhythmias .................................................................227 A. Inappropriate Sinus Tachycardia ................................................................227 B. Sinus Node Reentrant Tachycardia ............................................................229 C. Atrial Tachycardia/Atrial Flutter .................................................................231 D. Atrioventricular Nodal Reentrant Tachycardia ..........................................255 E. Atrioventricular Reentrant Tachycardia .....................................................283 F. Atrial Fibrillation .........................................................................................287 G. Junctional Rhythms ....................................................................................295 v Section 9 Wide Complex Arrhythmias .............................................................................297 A. Ventricular Tachycardia/Fibrillation ...........................................................297 B. Supraventricular Tachycardia (SVT) with Bundle Branch Block (BBB) ......355 C. Preexcited Tachycardia ...............................................................................371 D. Idioventricular Rhythm ...............................................................................373 Section 10 Ischemia and Infarction ....................................................................................375 Section 11 Electrolyte Disturbances, Pharmacological and Recreational Agents ..........413 Section 12 Paced Rhythms and Device Troubleshooting .................................................425 Section 13 Heart Failure, LVH, and Cardiomyopathies .....................................................459 A. Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) .........................................................459 B. Hypertrophic Cardiomyopathy (HCM) .......................................................479 C. Dilated Cardiomyopathy (DCM) .................................................................495 D. Chagas Cardiomyopathy ............................................................................501 E. Takotsubo (Stress) Cardiomyopathy ...........................................................511 F. Non-Compaction Cardiomyopathy ............................................................523 G. Pericarditis ...................................................................................................525 H. Other Cardiomyopathies ............................................................................529 Section 14 Congenital Heart Diseases ...............................................................................533 Section 15 Special Considerations: Age, Race, Gender, and Athletes .............................583 Section 16 Syncope and ECG Troubleshooting .................................................................593 Appendix ..............................................................................................................................621 vi u Contents Contributors Editors Contributors Mohammad Shenasa, MD, FACC, FHRS, Ahmed Abdel Aziz, MD, PhD FAHA, FESC Professor, Critical Care Medicine Department, Attending Physician, Department of Cairo University Hospitals, Cairo, Egypt Cardiovascular Services, O’Conner Hospital; Heart & Rhythm Medical Group, San Jose, Simon Abou Jaoude, MD California Cardiology Department, Hotel-Dieu de France, Saint Joseph University, Beirut, Lebanon Mark E. Josephson, MD, FACC, FHRS, FAHA Director, Harvard-Thorndike Electrophysiology Baris Akdemir, MD Institute and Arrhythmia Service; Cardiac Electrophysiology Fellow, Cardiology, Chief Emeritus, Division of Cardiovascular University of Minnesota, Minneapolis, Medicine, Beth Israel Deaconess Medical Minnesota Center; Herman C. Dana Professor of Medicine, Jason Andrade, BSc, MD, FRCPC, FHRS Harvard Medical School, Boston, Clinical Assistant Professor, Department of Massachusetts Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Adjunct N. A. Mark Estes III, MD, FACC, FHRS, Professor, Université de Montréal, Clinical FAHA, FESC Professor of Medicine, Tufts University School Electrophysiology Service, Montreal Heart of Medicine; Director, New England Cardiac Institute, Montreal, Quebec, Canada Arrhythmia Center, Tufts Medical Center, Samuel J. Asirvatham, MD, FACC, FHRS Boston, Massachusetts Consultant, Department of Cardiovascular Medicine, Division of Pediatric Cardiology, Ezra A. Amsterdam, MD Distinguished Professor, Associate Chief Department of Physiology and Biomedical (academic affairs), Division of Cardiovascular Engineering; Professor of Medicine and Medicine, University of California, Davis, Pediatrics, Mayo Clinic College of Medicine; Medical Center, Sacramento, California Program Director, EP Fellowship Program, Mayo Clinic, Rochester, Minnesota Melvin Scheinman, MD, FACC, FHRS Professor of Medicine, Walter H. Shorenstein Nitish Badhwar, MD, FACC, FHRS Endowed Chair in Cardiology; Chief of Director, Cardiac Electrophysiology Training Cardiology Genetics Arrhythmia Program, Program, Professor of Medicine, University of University of California, San Francisco, California, San Francisco, San Francisco, San Francisco, California California vii Adrian Baranchuk, MD, FACC, FRCPC, FCCS Catalin A. Buzea, MD, PhD Professor of Medicine (Tenure), Head, Heart Cardiology Consultant, Cardiology Rhythm Service, Queen’s University, Kingston, Department, Colentina University Hospital; Ontario, Canada Associate Professor, “Carol Davila” University of Medicine, Bucharest, Romania Raimundo Barbosa-Barros, MD Chief of Coronary Center, Messejana Hospital David J. Callans, MD, FHRS Dr. Carlos Alberto Studart Gomes, Fortaleza, Professor of Medicine, Perelman School of Ceará, Brazil Medicine; Associate Director of Electrophysiology, University of Pennsylvania Antoni Bayés de Luna, MD, PhD, FESC, FACC Health System, Philadelphia, Pennsylvania Senior Investigator, Catalan Institute of Cardiovascular Sciences, St. Pau Hospital, Francesc Carreras Costa, MD Barcelona, Spain Cardiology Department, Hospital Santa Creu i Sant Pau, Universitat Autónoma de Barcelona, Bernard Belhassen, MD, FHRS Barcelona, Spain Department of Cardiology, Tel-Aviv Sourasky Medical Center; Sackler Faculty of Medicine, Lily Chen, MD Tel-Aviv University, Tel-Aviv, Israel Resident of Internal Medicine, University of California, Davis, Medical Center, David G. Benditt, MD, FACC, FHRS, FRCPC, Sacramento, California FESC Cardiac Arrhythmia Center, Cardiovascular Alan Cheng, MD, FACC, FHRS, FAHA Division, University of Minnesota Medical Associate Professor of Medicine, Associate School, Minneapolis, Minnesota Professor of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Dan Blendea, MD, PhD, FHRS Maryland Cardiac Arrhythmia Service, Department of Medicine, Massachusetts General Hospital, Paolo China, MD Boston, Massachusetts Unit of Electrophysiology and Cardiac Pacing, Ospedale Dell’Angelo, Venice, Italy Pedro Brugada, MD, PhD Chairman, Cardiovascular Division, UZ Xavier Copie, MD Brussel, Brussels, Belgium Cardiologist, Arrhythmia Department, Centre Cardiologique du Nord, Saint-Denis, France Jonathan Bui, MD Research Assistant, Division of Cardiovascular Jane E. Crosson, MD Medicine, University of California, Davis, Associate Professor, Pediatrics, Johns Hopkins Medical Center, Sacramento, California Hospital, Baltimore, Maryland Haran Burri, MD Mohammad Dalili, MD Assistant Professor, Cardiology Department, Rajaie Cardiovascular Medical and Research University Hospital of Geneva, Geneva, Center, Iran University of Medical Sciences, Switzerland Tehran, Iran viii u Contributors Andrei G. Dan, MD, PhD, FESC, FAHA, Andrew E. Epstein, MD, FACC, FHRS, FAHA FEHRA Professor of Medicine, Electrophysiology Head of Cardiology Department and Internal Section, Cardiovascular Division, University of Medicine Clinic, Colentina University Hospital; Pennsylvania, Philadelphia, Pennsylvania Professor, “Carol Davila” University of Medicine, Bucharest, Romania Sabine Ernst, MD, PhD, FESC Consultant Cardiologist, Reader in Cardiology, Judith Daniels, RN, CRDS, CEPS Lead EP Researcher, Royal Brompton Hospital, Registered Nurse, EP Lab, Milpark Hospital, National Heart and Lung Institute, Imperial Johannesburg, Gauteng, South Africa College, London, United Kingdom Luiz Carlos de Abreu, PhD Luis Alberto Escobar Robledo, MS Chief, Design of Studies and Scientific Writing Fellow, Catalan Institute of Cardiovascular Laboratory, ABC School of Medicine, Santo Sciences, St. Pau Hospital, Barcelona, Spain André, São Paulo, Brazil; Program in Molecular and Integrative Physiological Sciences (MIPS), Tamer S. Fahmy, MD, PhD Associate Professor, Critical Care Medicine Department of Environmental Health, Harvard Department, Cairo University Hospitals, Cairo, T. H. Chan School of Public Health, Boston, Egypt Massachusetts Guy Fontaine, MD, PhD, HDR Arnaud Denis, MD Centre Hospitalier Pitié-Salpêtrière and Hôpital Cardiologique du Haut Lévèque, CHU Université Pierre et Marie Curie, Department of de Bordeaux, Université de Bordeaux and Rhythmology, Paris, France LYRIC Institute, Bordeaux, France Robert Frank, MD Nicolas Derval, MD Institut de Cardiologie, Hopital Pitié Hôpital Cardiologique du Haut Lévèque, CHU Salpétrière, Paris, France de Bordeaux, Université de Bordeaux and LYRIC Institute, Bordeaux, France Javier García-Niebla, RN Servicios Sanitarios del Area de Salud de El Marc Dubuc, MD, FRCPC, FACC, FHRS Hierro, Valle del Golfo Health Center, Canary Associate Professor of Medicine, Université de Island, Spain Montréal; Clinical Electrophysiology Service, Montreal Heart Institute, Montreal, Quebec, Diego Goldwasser, MD Canada Institut Cátala de Ciences Cardiovasculars, Sant Pau Hospital; Cardiology Department, Hospital Kenneth A. Ellenbogen, MD, FHRS Quiron Barcelona, Barcelona, Spain Kontos Professor of Medicine, Chair, Division of Cardiology, Virginia Commonwealth Judith A. Groeneweg, MD, PhD University, Pauley Heart Center, Richmond, University Medical Center Utrecht, The Virginia Netherlands Contributors u ix Majid Haghjoo, MD, FACC, FESC Heikki V. Huikuri, MD, PhD Director, Department of Cardiac Professor, Medical Research Center Oulu, Electrophysiology, Rajaie Cardiovascular Research Unit of Internal Medicine, University Medical and Research Center, Tehran, Iran of Oulu and Oulu University Hospital, Oulu, Finland Michel Haïssaguerre, MD, PhD Hôpital Cardiologique du Haut Lévèque, CHU James E. Ip, MD de Bordeaux, Université de Bordeaux and Assistant Professor of Medicine, Division of LYRIC Institute, Bordeaux, France Cardiology, Cardiac Electrophysiology Laboratory, Cornell University Medical Center, Frederick T. Han, MD, FACC, FHRS New York Presbyterian Hospital, New York, Assistant Professor of Medicine, Division of New York Cardiovascular Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah Pierre Jaïs, MD, PhD Hôpital Cardiologique du Haut Lévèque, CHU Richard N. Hauer, MD, PhD, FESC de Bordeaux, Université de Bordeaux and Professor of Cardiology, Netherlands Heart LYRIC Institute, Bordeaux, France Institute, University Medical Center Utrecht, The Netherlands Mohammad-Ali Jazayeri, MD Division of Cardiovascular Diseases, University Shahriar Heidary, MD, FACC of Kansas Hospital & Medical Center, Kansas Adjunct Clinical Instructor, Department of City, Kansas Internal Medicine, Division of Cardiovascular Medicine, Stanford University Medical School, Mohammad-Reza Jazayeri, MD Stanford, California Heart, Lung & Vascular, Bellin Health, Green Bay, Wisconsin Hein Heidbuchel, MD, PhD, FESC, FEHRA Professor and Chair, Department of Cardiology, Charles Jazra, MD, FACC, FESC Antwerp University Hospital, Antwerp, Cardiology Department, Saint Joseph Hospital, Belgium; Guest Professor, Cardiology, Hasselt Bauchrieh, Beirut, Lebanon University, Hasselt, Belgium Juhani Junttila, MD, PhD Mélèze Hocini, MD Associate Professor, Medical Research Center Hôpital Cardiologique du Haut Lévèque, CHU Oulu, Research Unit of Internal Medicine, de Bordeaux, Université de Bordeaux and University of Oulu and Oulu University LYRIC Institute, Bordeaux, France Hospital, Oulu, Finland Henry H. Hsia, MD, FACC, FHRS Gautham Kalahasty, MD Health Science Professor of Medicine, Program Director, Cardiology Fellowship University of California, San Francisco; Program, Virginia Commonwealth University, Chief, Arrhythmia Service, VA Medical Center, Pauley Heart Center, Richmond, Virginia San Francisco, California x u Contributors