The Curtis Center 170 S Independence Mall W 300E Philadelphia, Pennsylvania 19106 ECG IN EMERGENCY MEDICINE AND ACUTE CARE ISBN 0-323-01811-4 Copyright © 2005,Elsevier Inc. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier’s Health Sciences Rights Department in Philadelphia, PA, USA: phone: (+1) 215 238 7869, fax: (+1) 215 238 2239, e-mail: [email protected]. You may also complete your request on-line via the Elsevier homepage (http://www.elsevier.com), by selecting ‘Customer Support’and then ‘Obtaining Permissions.’ NOTICE Medicine is an ever-changing field. Standard safety precautions must be followed, but as new research and clinical experience broaden our knowledge, changes in treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current product information provided by the manufacturer of each drug to be administered to verify the recommended dose, the method and duration of administration, and contraindications. It is the responsibility of the treating physician, relying on experience and knowledge of the patient, to determine dosages and the best treatment for each individual patient. Neither the Publisher nor the editor assumes any liability for any injury and/or damage to persons or property arising from this publication. The Publisher Library of Congress Cataloging-in-Publication Data ECG in emergency medicine and acute care/[edited by] Theodore C. Chan—[et al.].—1st ed. p. ; cm. Includes bibliographical references. ISBN 0-323-01811-4 1. Electrocardiography. 2. Cardiovascular emergencies. I. Chan, Theodore C. [DNLM: 1. Electrocardiography—methods. 2. Emergency Medicine—instrumentation. WG 140 E1715 2005] RC683.5.E5E246 2005 616.1’207547—dc22 2003071094 Acquisitions Editor:Todd Hummel Developmental Editor:Carla Holloway Publishing Services Manager:Frank Polizzano Senior Project Manager:Natalie Ware Design Coordinator:Karen O’Keefe Owens Printed in the United States of America Last digit is the print number: 9 8 7 6 5 4 3 2 1 I would like to thank Peter Rosen, my friend and mentor, for his inspiration and encouragement. A lifetime of thanks is due to my parents, Eva and Lun Chan, whose guidance and example set me on my path. Finally, I would like to thank my wife, Diana, and our children, Taylor James and Lauren, for their understanding, flexibility, support, and love, which have helped me keep perspective on what is truly important in life. TCC I would like to thank my wife, King, for her support, guidance, love, and patience; my children, Lauren, Anne, Chip, and Katherine, for their love; my parents, Joann and Bill Brady, for all they’ve done and continue to do; the Emergency Medicine Residents at the University of Virginia, for their devotion to our patients and Emergency Medicine; and to my co-editors, for their support, understanding, guidance, and, most of all, their friendship. WJB To my parents, Tom and Ruth Harrigan, thank you for being all that you are, which is more than you know. To Noreen, thank you so much for selflessly giving the time, support, and patience necessary to complete this project. To Quinn and Kelly, thank you for being the perfect answer to what is important. RAH I would like to dedicate this book to the family of Emergency Medicine practition- ers, residents, and students who strive to provide the highest quality care to our patients with cardiovascular disease. JPO I would like to add my thanks to my coeditors whose labor and erudition have helped to keep me educated, and whose efforts will translate into much improved care of patients who rely on our knowledge. PR v Editors Theodore C. Chan, MD, FACEP, FAAEM Joseph P. Ornato, MD, FACP, FACC, FACEP Associate Professor of Clinical Medicine, Professor and Chairman, Assistant Clinical Director, Department of Emergency Medicine, Department of Emergency Medicine, Virginia Commonwealth University Medical Center, University of California, San Diego, Richmond, Virginia San Diego, California 75: Body Surface Mapping 8: Tachydysrhythmias, 10: P Wave, 11: PR Interval and Segment, 16: U Wave, 27: Pacemakers: Normal Peter Rosen, MD, FAAEM Function, 28: Pacemakers: Abnormal Function, Senior Lecturer, Department of Medicine, 37: Myopericarditis, and 49: Toxicology Section: Harvard University, Beth Israel/Deaconess Hospital, Introduction Boston, Massachusetts; Visiting Professor, William J. Brady, Jr., MD, FACEP, FAAEM Department of Emergency Medicine, Associate Professor and Vice Chair, University of Arizona School of Medicine, Department of Emergency Medicine, Tucson, Arizona; Associate Professor, Attending Emergency Physician, Department of Internal Medicine, Beth Israel/Deaconess Hospital, University of Virginia School of Medicine, Boston, Massachusetts; Charlottesville, Virginia; Attending Emergency Physician, Medical Director, Life Support Learning Center St. John’s Hospital, Jackson, Wyoming University of Virgina Health System, Charlottesville, Virginia 7: Bradydysrhythmias, 13: ST Segment, 14: T Wave, 20: Atrioventricular Block, 25: Preexcitation Syndromes, 34: Acute Myocardial Infarction: Confounding Patterns, 40: Benign Early Repolarization, 47: Long QT Syndromes, and 71: The Prehospital 12-Lead Electrocardiogram Richard A. Harrigan, MD, FAAEM Associate Professor of Emergency Medicine, Temple University Hospital and School of Medicine, Philadelphia, Pennsylvania 6: Dysrhythmias at Normal Rates, 9: Abnormal Axis, 12: QRS Complex, 15: QT Interval, 20: Atrioventricular Block, 30: Atrioventricular Dissociation, 55: Tricyclic Antidepressant Agents, and 62: Pneumothorax vi Contributors Douglas S. Ander, MD Steven L. Bernstein, MD Associate Professor, Assistant Professor, Department of Emergency Medicine, Department of Emergency Medicine, Albert Einstein College of Medicine, Bronx, New York; Emory University School of Medicine, Attending Physician, Department of Emergency Medicine, Atlanta, Georgia Montefiore Medical Center, 38: Myocarditis Bronx, New York 64: Neurologic and Neuromuscular Conditions, Tom P. Aufderheide, MD, FACEP 65: Rheumatologic/Immunologic Disorders Professor of Emergency Medicine, Department of Emergency Medicine, Thomas P. Bleck, MD, FCCM Medical College of Wisconsin, Louise Nerancy Eminent Scholar in Neurology and Milwaukee, Wisconsin Professor of Neurology, Neurological Surgery, and 71: The Prehospital 12-Lead Electrocardiogram, Internal Medicine, 73: QT Dispersion, and 74: Electrocardiographic Department of Neurology, Predictive Instruments University of Virginia, Charlottesville, Virginia; Director, Neuroscience Intensive Care Unit, Alexander B. Baer, MD University of Virginia, Clinical Instructor, Department of Emergency Medicine, Charlottesville, Virginia University of Virginia Health System, 64: Neurologic and Neuromuscular Conditions Charlottesville, Virginia 56: Other Sodium Channel Blocking Agents Ioliene Boenau, MD Assistant Director, James Dave Barry, MD Emergency Medicine Residency Program, Faculty Emergency Medicine Physician, Eastern Virginia Medical School, Emergency Department, Brooke Army Medical Center, Norfolk, Virginia San Antonio, Texas; Staff Emergency Medicine Physician, 29: Sick Sinus Syndrome San Antonio Uniformed Services Health Education Consortium Emergency Medicine Residency, Michael J. Bono, MD, FACEP San Antonio, Texas Associate Professor of Emergency Medicine, 51: Beta-Adrenergic Blocking Agents Department of Emergency Medicine, Eastern Virginia Medical School, Todd J. Berger, MD Norfolk, Virginia; Associate Program Director, Assistant Professor, Assistant Residency Director, Emergency Medicine Residency Program, Department of Emergency Medicine, Department of Emergency Medicine, Emory University, Atlanta, Georgia; Eastern University Medical School, Attending Physician, Norfolk, Virginia Department of Emergency Medicine, 36: Cardiomyopathy Grady Memorial Hospital, Atlanta, Georgia Kenneth J. Bramwell, MD 66: Acute Rheumatic Fever Director, Pediatric Emergency Medicine, Emergency Medicine of Idaho, James D. Bergin, MD St. Luke’s Regional Medical Center, Associate Professor of Medicine, Boise, Idaho Department of Medicine, 5: The Pediatric Electrocardiogram University of Virginia, Charlottesville, Virginia 44: Cardiac Transplant vii viii CONTRIBUTORS Joseph S. Bushra, MD Brian F. Erling, MD Adjunct Assistant Professor, Chief Resident, Department of Emergency Medicine, Department of Emergency Medicine, University of Virginia, Charlottesville, Virginia Temple University School of Medicine, 1: Standard 12-Lead Electrocardiogram: Principles and Philadelphia, Pennsylvania; Attending Physician, Techniques, 31: Waveform Genesis in Acute Coronary Department of Emergency Medicine, Syndrome, and 46: Cardiac Trauma The Lankenau Hospital, Wynnewood, Pennsylvania 2: The Normal Electrocardiogram and Its Timothy C. Evans, MD Interpretation Associate Professor of Emergency Medicine, Program Director, Taylor Y. Cardall, MD Department of Emergency Medicine, Emergency Physician, Department of Emergency Medicine, Virginia Commonwealth University Medical Center, Scottsdale Healthcare, Scottsdale, Arizona Medical College of Virginia, Richmond, Virginia 27: Pacemakers: Normal Function, and 28: Pacemakers: 35: Ventricular Hypertrophy Abnormal Function Jeffrey D. Ferguson, MD, NREMT-P Leslie S. Carroll, MD, ABMT Department of Emergency Medicine, Assistant Professor, Department of Emergency Medicine, University of Virginia Health System, Temple University, Philadelphia, Pennsylvania Charlottesville, Virginia; 54: Antipsychotic Agents and Lithium Charlottesville-Albemarle Rescue Squad, Charlottesville, Virginia Richard F. Clark, MD 71: The Prehospital 12-Lead Electrocardiogram Professor, Department of Medicine, University of California, San Diego, Renee Yvette Friday, MD, MPH, FAAP, FACC San Diego, California; Assistant Professor of Pediatrics, Director, Division of Medicine Toxicology, Department of Pediatric Cardiology, University of California, San Diego Medical Center, University of Texas Medical Branch Galveston, San Diego, California; Medical Director, Galveston, Texas California Poison Control System, San Diego Division, 48: Congenital Heart Disease San Diego, California 53: Other Cardioactive Agents J. Lee Garvey, MD Medical Director, Chest Pain Evaluation Center, M. Todd Clever, MD Department of Emergency Medicine, Medical College of Wisconsin, Carolinas Medical Center, Milwaukee, Wisconsin Charlotte, North Carolina 71: The Prehospital 12-Lead Electrocardiogram 70: Serial Electrocardiography and ST Segment Trend Monitoring Francis L. Counselman, MD, FACEP EVMS Distinguished Professor of Emergency Medicine, Paolo M. Gazoni, MD Department of Emergency Medicine, Assistant Professor, Eastern Virginia Medical School, Norfolk, Virginia; Department of Emergency Medicine, Virginia Chairman and Program Director, Commonwealth University Health System, Department of Emergency Medicine, Richmond, Virginia Eastern Virginia Medical School, Norfolk, Virginia 35: Ventricular Hypertrophy 43: Pericardial Effusion Christopher R. George, MD Wendy M. Curulla, MD Senior Resident, Department of Emergency Medicine, Instructor, Department of Emergency Medicine, Medical College of Wisconsin, Eastern Virginia Medical School, Norfolk, Virginia Milwaukee, Wisconsin 29: Sick Sinus Syndrome 74: Electrocardiographic Predictive Instruments Kurt R. Daniel, DO Chris A. Ghaemmaghami, MD Chief Resident, Department of Internal Medicine, Associate Professor of Emergency Medicine and Wake Forest University, Winston-Salem, North Carolina Internal Medicine, 59: Pulmonary Embolism Department of Emergency Medicine, University of Virginia, Charlottesville, Virginia 60: Chronic Obstructive Pulmonary Disease CONTRIBUTORS ix W. Brian Gibler, MD Attending Physician, Professor and Chairman, Department of Emergency Medicine, Lourdes Medical Center of Burlington County, University of Cincinnati College of Medicine, Willingboro, New Jersey Cincinnati, Ohio; 30: Atrioventricular Dissociation Director, Center for Emergency Care, University Hospital, Cincinnati, Ohio Timothy G. Janz, MD, FACEP, FCCP Foreword Professor, Department of Emergency Medicine, Wright State University School of Medicine, Melody C. Graves, DO Dayton, Ohio Senior Resident, Department of Emergency Medicine, 33: Acute Coronary Syndromes: Regional Issues Medical College of Wisconsin, Milwaukee, Wisconsin 73: QT Dispersion Sharone Jensen, MD Attending Physician, Our Lady of Lourdes Medical Center, Glenn C. Hamilton, MD Camden, New Jersey Professor and Chair, Department of Emergency Medicine, 26: Ventricular Tachycardia and Ventricular Fibrillation Wright State University School of Medicine, Dayton, Ohio David J. Karras, MD 33: Acute Coronary Syndromes: Regional Issues Associate Professor of Emergency Medicine, Associate Chair for Academic Affairs and Director of Research, Richard J. Harper, MS, MD Department of Emergency Medicine, Assistant Professor, Department of Emergency Medicine, Temple University School of Medicine, Oregon Health and Sciences University, Portland, Oregon; Philadelphia, Pennsylvania Chief of Emergency Medicine, 67: Miscellaneous Infectious Syndromes: Lyme Carditis, Emergency Medicine Service, Portland-VAMC, Human Immunodeficiency Virus-Associated, and Chagas Disease Portland, Oregon 4: Electrode Misplacement and Artifact, 41: Ventricular Varnada A. Karriem-Norwood, MD Aneurysm, and 42: Valvular Disorders Assistant Professor of Emergency Medicine, Katherine L. Heilpern, MD Assistant Medical Director, Grady Emergency Care Center, Department of Emergency Medicine, Emory University, Associate Professor and Vice Chair for Academic Affairs, Atlanta, Georgia; Assistant Medical Director, Department of Emergency Medicine, Emergency Care Center, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, Georgia Atlanta, Georgia 39: Endocarditis 38: Myocarditis, 39: Endocarditis, and 66: Acute Rheumatic Fever A. Antoine Kazzi, MD, FAAEM Robert S. Hoffman, MD Vice Chair and Associate Professor of Clinical Associate Professor, Emergency Medicine, Departments of Emergency Medicine and Medicine, Department of Emergency Medicine, New York University School of Medicine, University of California, Irvine, Orange, California New York, New York; 24: Other Supraventricular Tachydysrhythmias Director, New York City Poison Center, Department of Health and Mental Hygiene, Mark A. Kirk, MD New York, New York Director, Medical Toxicology Fellowship, 57: Cocaine and Other Sympathomimetics Department of Emergency Medicine, University of Virginia, Charlottesville, Virginia Christopher P. Holstege, MD 50: Digitalis Director, Division of Medical Toxicology, Assistant Professor, Department of Emergency Medicine, Jeffrey A. Kline, MD University of Virginia, Charlottesville, Virginia Director of Research, Department of Emergency Medicine, 50: Digitalis, and 56: Other Sodium Channel Carolinas Medical Center, Charlotte, North Carolina; Blocking Agents Associate Professor, Department of Emergency Medicine, University of North Carolina, Chapel Hill, Lawrence Isaacs, MD, FACEP, FAAEM North Carolina Assistant Professor (Adjunct) of Emergency Medicine, 59: Pulmonary Embolism Department of Emergency Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania; x CONTRIBUTORS Michael C. Kontos, MD Moss Mendelson, MD Associate Director, Acute Cardiac Care, Assistant Professor, Associate Professor, Department of Emergency Medicine, Departments of Internal Medicine (Division of Cardiology), Eastern Virginia Medical School, Norfolk, Virginia Emergency Medicine, and Radiology, 45: Dextrocardia Virginia Commonwealth University, Richmond, Virginia 72: The Electrocardiogram and Stress Testing Steven R. Offerman, MD Assistant Professor, Division of Emergency Medicine and Brian Korotzer, MD Clinical Toxicology, Assistant Chief, Department of Internal Medicine, University of California Davis, Kaiser Permanente, Bellflower, California; Sacramento, California Assistant Clinical Professor of Medicine, 52: Calcium Channel Antagonists David Geffen School of Medicine at UCLA, Los Angeles, California Sonal M. Patel, MD 61: Pulmonary Hypertension Clinical Fellow, Department of Gastroenterology, Beth Israel Deaconess Medical Center, John R. Lindbergh, MD Boston, Massachusettes Assistant Professor of Emergency Medicine, 68: Electrocardiographic Manifestations of Emergency Department, University of Virginia, Gastrointestinal Diseases Charlottesville, Virginia; Emergency Physician, Emergency Department, Martha Jefferson Hospital, Andrew D. Perron, MD, FACEP, FACSM Charlottesville, Virginia Residency Program Director, 25: Preexcitation Syndromes Department of Emergency Medicine, Maine Medical Center, Portland, Maine Binh T. Ly, MD 1: Standard 12-Lead Electrocardiogram: Principles and Assistant Clinical Professor, Techniques, and 31: Waveform Genesis in Acute Department of Emergency Medicine, Coronary Syndrome University of California,San Diego Medical Center, San Diego, California Jesse M. Pines, MD, MBA 52: Calcium Channel Antagonists Lecturer, Department of Emergency Medicine, University of Pennsylvania School of Medicine, Marcus L. Martin, MD Philadelphia, Pennsylvania Professor and Chair, 47: Long QT Syndromes Department of Emergency Medicine, University of Virginia, Charlottesville, Virginia Sridevi R. Pitta, MBBS 40: Benign Early Repolarization Department of Emergency Medicine, Department of Internal Medicine, John Matjucha, MD Wayne State University, Detroit, Michigan Department of Emergency Medicine, 69: Additional Lead Electrocardiograms Newark Beth Israel Medical Center, Newark, New Jersey Marc L. Pollack, MD, PhD 65: Rheumatologic/Immunologic Disorders Research Director, Department of Emergency Medicine, York Hospital, York, Pennsylvania Amal Mattu, MD 34: Acute Myocardial Infarction: Confounding Patterns Co-Director, Emergency Medicine/Internal Medicine Combined Residency, Director of Academic Development, Christopher F. Richards, MD Emergency Medicine Residency, Associate Professor, Department of Emergency Medicine, University of Maryland School of Medicine, Oregon Health and Sciences University, Portland, Oregon; Baltimore, Maryland Chief, Acute Clinical Care, 21: Intraventricular Conduction Abnormalities Department of Emergency Medicine, Oregon Health and Sciences University, Nancy L. McDaniel, MD Portland, Oregon Associate Professor of Pediatric Cardiology, 4: Electrode Misplacement and Artifact, and Department of Pediatrics, University of Virginia, 42: Valvular Disorders Charlottesville, Virginia Robert L. Rogers, MD 48: Congenital Heart Disease Assistant Professor and Program Director, Bryon K. McNeil, MD Emergency Medicine/Internal Medicine Combined Residency, University of Maryland School of Medicine, Attending Physician, Emergency Department, Baltimore, Maryland Christi Regional Medical Center, Wichita, Kansas 21: Intraventricular Conduction Abnormalities 62: Pneumothorax CONTRIBUTORS xi Pamela A. Ross, MD Jacob W. Ufberg, MD Assistant Professor, Clinical, Assistant Residency Program Director, Departments of Emergency Medicine and Pediatrics, Department of Emergency Medicine, University of Virginia Health System, Temple University School of Medicine, Charlottesville, Virginia Philadelphia, Pennsylvania 48: Congenital Heart Disease 17: Bradycardia and Escape Rhythms, 18: Sinus Pause/Sinus Arrest, and 19: Sinoatrial Exit Block Joshua G. Schier, MD Assistant Professor, Department of Emergency Medicine, Edward Ullman, MD Emory University School of Medicine, Attending Physician, Department of Emergency Medicine, Atlanta, Georgia; Beth Israel Deaconess Medical Center, Medical Toxicology Attending, Boston, Massachusetts Emory/CDC Medical Toxicology Fellowship, 68: Electrocardiographic Manifestations of Georgia Poison Control Center, Atlanta, Georgia Gastrointestinal Diseases 57: Cocaine and Other Sympathomimetics Michael J. Urban, MD Aaron B. Schneir, MD Senior Resident, Department of Emergency Medicine, Assistant Professor, Department of Emergency Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin University of California, San Diego Medical Center, 71: The Prehospital 12-Lead Electrocardiogram San Diego, California 53: Other Cardioactive Agents Robert A. VerNooy, MD Electrophysiology Fellow, George M. Shumaik, MD Department of Internal Medicine, Clinical Professor of Medicine, Cardiovascular Division, Department of Emergency Medicine, University of Virginia Health System, University of California, San Diego School of Medicine, Charlottesville, Virginia San Diego, California; 44: Cardiac Transplant Medical Director, Department of Emergency Medicine, University of California, San Diego Medical Center, Gary M. Vilke, MD San Diego, California Associate Professor of Clinical Medicine, 58: Electrolyte Abnormalities Department of Emergency Medicine, University of California,San Diego Medical Center, Stephen W. Smith, MD, FACEP San Diego, California Associate Professor of Emergency Medicine, 3: Variants of Normal Department of Emergency Medicine, University of Minnesota School of Medicine, Robert P. Wahl, MD Minneapolis, Minnesota Assistant Professor (Clinical Educator), 32: Acute Coronary Syndromes: Acute Myocardial Department of Emergency Medicine, Infarction and Ischemia Wayne State University/Detroit Medical Center, Detroit, Michigan; Teresa L. Smith, MD Emergency Medicine Residency Program Director, Clinical Assistant Professor, Department of Emergency Medicine, Michigan State University College of Human Medicine, Wayne State University/Detroit Medical Center, Kalamazoo, Michigan; Detroit, Michigan Medical Director, Adult Neurology, 69: Additional Lead Electrocardiograms Bronson Methodist Hospital, Kalamazoo, Michigan 64: Neurologic and Neuromuscular Conditions David A. Wald, DO Director of Undergraduate Medical Education, Sarah A. Stahmer, MD Assistant Professor of Emergency Medicine, Associate Professor, Department of Emergency Medicine, Department of Emergency Medicine, Robert Wood Johnson/UMDNJ Medical School, Temple University School of Medicine, Camden, New Jersey; Philadelphia, Pennsylvania; Attending Physician, Program Director, Department of Emergency Medicine, Department of Emergency Medicine, Cooper Hospital/University Medical Center, Temple University Hospital, Camden, New Jersey Philadelphia, Pennsylvania 26: Ventricular Tachycardia and Ventricular Fibrillation 63: Endocrine and Metabolic Disorders xii CONTRIBUTORS Christopher J. Ware, MD Keith Wrenn, MD Department of Emergency Medicine, Professor and Program Director, Temple University School of Medicine, Department of Emergency Medicine, Philadelphia, Pennsylvania Vanderbilt University School of Medicine, 17: Bradycardia and Escape Rhythms Nashville, Tennessee 22: Atrial Fibrillation and Atrial Flutter, and Wayne Whitwam, MD 23: Wandering Atrial Pacemaker and Multifocal Atrial Tachycardia Fellow, Division of Cardiology, Department of Emergency Medicine, Jeffrey S. Young, MD, FACS Wayne State University School of Medicine, Detroit, Michigan; Associate Professor of Surgery and Health Fellow, Division of Cardiology, Evaluation Sciences, Department of Internal Medicine, Harper Hospital, Department of Surgery, Detroit, Michigan University of Virginia Health System, Charlottesville, Virginia; 32: Acute Coronary Syndromes: Acute Myocardial Infarction and Ischemia Director, Trauma Center, Department of Surgery, Saralyn R. Williams, MD, FACMT, FACEP University of Virginia Health System, Charlottesville, Virginia Associate Clinical Professor of Medicine, Department of Medicine, 46: Cardiac Trauma University of California, San Diego, San Diego, California Robert J. Zalenski, MD, MA 51: Beta-Adrenergic Blocking Agents Professor, Department of Emergency Medicine, Wayne State University School of Medicine, Hubert Wong, MD, RDMS, FACEP Detroit, Michigan; Attending Physician, Department of Medicine, Director of Emergency Ultrasound, John D. Dingell Veterans Hospital, Department of Emergency Medicine, Urgent Care Center, Loma Linda University Medical Center, Detroit, Michigan Loma Linda, California 69: Additional Lead Electrocardiograms 24: Other Supraventricular Tachydysrhythmias
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