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Ebola : profile of a killer virus PDF

222 Pages·2016·1.69 MB·English
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Ebola Ebola slogan on a wall in Freetown, Sierra leone, 2015. Ebola Profile of a Killer Virus Dorothy h. CrawforD 1 1 Great Clarendon Street, oxford, ox2 6dp, United Kingdom oxford University Press is a department of the University of oxford. It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide. oxford is a registered trade mark of oxford University Press in the UK and in certain other countries © Dorothy H. Crawford 2016 The moral rights of the author have been asserted First Edition published in 2016 Impression: 1 all rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in writing of oxford University Press, or as expressly permitted by law, by licence or under terms agreed with the appropriate reprographics rights organization. Enquiries concerning reproduction outside the scope of the above should be sent to the Rights Department, oxford University Press, at the address above You must not circulate this work in any other form and you must impose this same condition on any acquirer Published in the United States of america by oxford University Press 198 Madison avenue, New York, NY 10016, United States of america british library Cataloguing in Publication Data Data available library of Congress Control Number: 2016943467 ISbN 978–0–19–875999–7 Printed in Great britain by Clays ltd, St Ives plc links to third party websites are provided by oxford in good faith and for information only. oxford disclaims any responsibility for the materials contained in any third party website referenced in this work This book is dedicated to Dr Jean Alero Thomas (1945–2015) aCKNowlEDGEMENTS I would like to thank all those experts who helped and advised on the writing of this book: Tim brooks, Public Health England, Jeremy Farrar, wellcome Trust, Ian Goodfellow, University of Cambridge, brian Greenwood, london School of Hygiene and Tropical Medicine, David Heymann, Public Health England and Centre on Global Health Security, Paul Johnson, Public Health England, Peter Piot, london School of Hygiene and Tropical Medicine, and Katrina Roper, world Health organization. I am also indebted to the following for reading and commenting on the manuscript: william alexander, Martin allday, Jeanne bell, Richard boyd, Jude Fantes, Tanzina Haque, Ingolfur Johannessen, barbara Judge, Jim Piper, Iain Ritchie, Paul Saba, bobby Stansfield, Tara womersley, and to latha Menon at oxford University Press for her constant support. I am particularly grateful to Frances Fowler, who facilitated my meetings with Ebola experts, and Tim brooks, who allowed me to shadow him for a short time while he went about his busy sched- ule in Sierra leone in april 2015. vii CoNTENTS List of Figures xi Abbreviations xiii Introduction 1 1. when Disaster Strikes: The First Ebola outbreak 6 2. Ebola: The Virus and the Disease 27 3. Ebola: The Years after Yambuku 49 4. Ebola Strikes west africa: The Catastrophic Events of 2014 73 5. Ebola Epidemic: The Fight back 91 6. Ebola Epidemic: The Endgame 113 7. 2014 Ebola Epidemic: where, when, and How? 136 8. Preventing Ebola 147 9. lessons learned 169 Postscript 179 Glossary 181 Notes 185 Index 197 ix

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First discovered in 1976, and long regarded as an easily manageable virus affecting isolated rural communities, Ebola rocketed to world prominence in 2014 as a deadly epidemic swept through Guinea, Sierra Leone, and Liberia in West Africa. Thousands of people died as the extraordinarily contagious d
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