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Drugs and society PDF

717 Pages·2018·170.81 MB·English
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DRUGS AND SOCIETY T H I R T E E N T H E D I T I O N GLEN R. HANSON, PhD, DDS PETER J. VENTURELLI, PhD ANNETTE E. FLECKENSTEIN, PhD Associate Dean Professor Emeritus  Professor Director, Utah Addiction Center Department of Sociology and School of Dentistry Professor Criminology University of Utah School of Dentistry Valparaiso University Salt Lake City, Utah University of Utah Valparaiso, Indiana Salt Lake City, Utah World Headquarters Jones & Bartlett Learning 5 Wall Street Burlington, MA 01803 978-443-5000 [email protected] www.jblearning.com Jones & Bartlett Learning books and products are available through most bookstores and online booksellers. To contact Jones & Bartlett Learning directly, call 800-832-0034, fax 978-443-8000, or visit our website, www.jblearning.com. Substantial discounts on bulk quantities of Jones & Bartlett Learning publications are available to corporations, professional associations, and other qualified organizations. For details and specific discount information, contact the special sales department at Jones & Bartlett Learning via the above contact information or send an email to specialsales@ jblearning.com. Copyright © 2018 by Jones & Bartlett Learning, LLC, an Ascend Learning Company All rights reserved. No part of the material protected by this copyright may be reproduced or utilized in any form, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without written permission from the copyright owner. The content, statements, views, and opinions herein are the sole expression of the respective authors and not that of Jones & Bartlett Learning, LLC. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise does not constitute or imply its endorsement or recommendation by Jones & Bartlett Learning, LLC and such reference shall not be used for advertising or product endorsement purposes. All trademarks displayed are the trademarks of the parties noted herein. Drugs and Society, Thirteenth Edition is an independent publication and has not been authorized, sponsored, or otherwise approved by the owners of the trademarks or service marks referenced in this product. There may be images in this book that feature models; these models do not necessarily endorse, represent, or participate in the activities represented in the images. Any screenshots in this product are for educational and instructive purposes only. Any individuals and scenarios featured in the case studies throughout this product may be real or fictitious, but are used for instructional purposes only. 11098-2 Production Credits VP, Executive Publisher: David D. Cella Cover and Title Page Images: A rocks glass, © Yeko Photo Publisher: Cathy L. Esperti Studio/ShutterStock, Inc.; Three pills, © Maksud/ Editorial Assistant: Carter McAlister ShutterStock, Inc.; An iced coffee, © Yeko Photo Studio/ Director of Production: Jenny L. Corriveau ShutterStock, Inc.; Rolling a joint, © Nikita Starichenko/ Production Editor: Kristen Rogers ShutterStock, Inc.; Steroids used by an athlete, © Director of Marketing: Andrea DeFronzo Jupiterimages/liquidlibrary/Thinkstock; An aisle of pills, VP, Manufacturing and Inventory Control: Therese Connell © Jupiterimages/Photos.com/Thinkstock; A spray can, © Composition: Cenveo® Publisher Services Mikael Damkier/ShutterStock, Inc.; A cigarette, © Mariusz Cover Design: Michael O’Donnell Szachowski/ShutterStock, Inc.; A drug user, © iStockphoto/ Director of Rights & Media: Joanna Gallant Thinkstock Rights & Media Specialist: Jamey O’Quinn Printing and Binding: LSC Communications Media Development Editor: Troy Liston Cover Printing: LSC Communications Library of Congress Cataloging-in-Publication Data Names: Hanson, Glen (Glen R.), author. | Venturelli, Peter J., author. | Fleckenstein, Annette E., author. Title: Drugs and society / Dr. Glen R. Hanson, Peter J. Venturelli, Annette E. Fleckenstein. Description: 13e. | Burlington, MA : Jones & Bartlett Learning, [2018] | Includes bibliographical references and index. Identifiers: LCCN 2016043260 | ISBN 9781284110876 (pbk.: alk. paper) Subjects: | MESH: Substance-Related Disorders Classification: LCC RM301 | NLM WM 270 | DDC 362.29—dc23 LC record available at https://lccn.loc.gov/2016043260 6048 Printed in the United States of America 21 20 19 18 17 10 9 8 7 6 5 4 3 2 1 brief contents CHAPTER 1 CHAPTER 11 Introduction to Drugs and Society 1 Tobacco 366 CHAPTER 2 CHAPTER 12 Explaining Drug Use and Abuse 65 Hallucinogens (Psychedelics) 383 CHAPTER 3 CHAPTER 13 Drug Use, Regulation, Marijuana 416 and the Law 112 CHAPTER 14 CHAPTER 4 Inhalants 467 Homeostatic Systems and Drugs 135 CHAPTER 15 Over-the-Counter, Prescription, CHAPTER 5 and Herbal Drugs 476 How and Why Drugs Work 157 CHAPTER 16 CHAPTER 6 Drug Use in Subcultures CNS Depressants: of Special Populations 519 Sedative-Hypnotics 184 CHAPTER 17 CHAPTER 7 Drug Abuse Prevention 603 Alcohol: Pharmacological Effects 206 CHAPTER 18 Treating Drug Dependence 645 CHAPTER 8 Alcohol: Behavioral Effects 233 APPENDIX A Federal Agencies with CHAPTER 9 Drug Abuse Missions 659 Narcotics (Opioids) 287 APPENDIX B CHAPTER 10 Drugs of Use and Abuse 661 Stimulants 320 ❚ iii contents Features xi Employee Assistance Programs 53 Preface xiii Venturing to a Higher Form of Consciousness: The Holistic How to Use This Book xvi Self-Awareness Approach to Drug Use 55 Acknowledgments xxi About the Authors xxii CHAPTER 2 Explaining Drug Use and Abuse 65 CHAPTER 1 Introduction to Drugs and Society 1 Introduction 66 Drug Use: A Timeless Affliction 68 Introduction 2 The Origin and Nature of Addiction 70 Drug Use 3 Defining Addiction 71 Dimensions of Drug Use 3 Models of Addiction 72 Major Types of Commonly Abused Drugs 10 Factors Contributing to Addiction 73 Prescription and Performance- The Vicious Cycle of Drug Addiction 75 Enhancing Drugs 10 Other Nondrug Addictions 75 Stimulants 12 Major Theoretical Explanations: Biological 76 Bath Salts 12 Abused Drugs as Positive Reinforcers 77 Hallucinogens/Psychedelics Drug Abuse and Psychiatric Disorders 77 and Other Similar Drugs 12 Genetic Explanations 77 Depressants 13 Alcohol 13 Major Theoretical Explanations: Nicotine 13 Psychological 81 Cannabis (Marijuana and Hashish) 13 Distinguishing Between Substance Designer Drugs/Synthetic Abuse and Mental Disorders 81 Drugs or Synthetic Opioids 13 The Relationship Between Anabolic Steroids 16 Personality and Drug Use 82 Inhalants/Organic Solvents 16 Theories Based on Learning Processes 83 Narcotics/Opiates 17 Social Psychological Learning Theories 85 An Overview of Drugs in Society 17 Major Theoretical Explanations: How Widespread Is Drug Abuse? 17 Sociological 85 Extent and Frequency of Drug Use in Society 19 Social Influence Theories 86 Drug Use: Statistics, Structural Influence Theories 97 Trends, and Demographics 24 Danger Signals of Drug Abuse 102 Current Patterns of Licit and Illicit Drug Use 29 Low-Risk and High-Risk Drug Choices 103 Types of Drug Users 35 Drug Use: Mass and Electronic Media and Family Influences 37 CHAPTER 3 Drug Use and Drug Dependence 40 When Does Use Lead to Abuse? 41 Drug Use, Regulation, and the Law 112 Drug Dependence 42 The Costs of Drug Use to Society 43 Introduction 113 Drugs, Crime, and Violence 45 Cultural Attitudes About Drug Use 113 Drugs in the Workplace: A Persistent Affliction 50 The Road to Regulation and the FDA 113 iv ❚ Contents ❚ v The Rising Demand for The Dose–Response Relationship Effectiveness in Medicinal Drugs 116 of Therapeutics and Toxicity 159 Regulating the Margin of Safety 160 Development of New Drugs 116 Potency Versus Toxicity 160 The Effects of the OTC Review Drug Interaction 161 on Today’s Medications 119 Additive Effects 161 The Regulation of Drug Advertising 120 Antagonistic (Inhibitory) Effects 161 Federal Regulation and Quality Assurance 121 Potentiative (Synergistic) Effects 161 Drug Abuse and the Law 121 Dealing with Drug Interactions 162 Drug Laws and Deterrence 125 Pharmacokinetic Factors Factors in Controlling Drug Abuse 125 That Influence Drug Effects 163 Strategies for Preventing Drug Abuse 126 Forms and Methods of Taking Drugs 164 Supply Reduction Strategy 126 Distribution of Drugs in the Body Demand Reduction Strategy 127 and Time–Response Relationships 166 Inoculation Strategy 127 Inactivation and Elimination Drug Courts 128 of Drugs from the Body 169 Physiological Variables That Current and Future Drug Use 128 Modify Drug Effects 170 Drug Legalization Debate 128 Pathological Variables Drug Testing 130 That Modify Drug Effects 171 Pragmatic Drug Policies 131 Pharmacokinetics and Drug Testing 171 Adaptive Processes and Drug Abuse 171 Tolerance to Drugs 172 CHAPTER 4 Drug Dependence 175 Homeostatic Systems and Drugs 135 Psychological Factors 176 The Placebo Effect 176 Introduction 136 Addiction (Substance Use Disorder) Overview of Homeostasis and Abuse: The Significance and Drug Actions 136 of Dependence 177 Section 1: Introduction to Hereditary Factors 177 Nervous Systems 136 Drug Craving 177 Other Factors 178 Section 2: Comprehensive Explanation of Homeostatic Systems 138 The Building Blocks of the Nervous System 139 CHAPTER 6 Major Divisions of the Nervous System 147 CNS Depressants: The Autonomic Nervous System 149 Sedative-Hypnotics 184 The Endocrine System 150 Conclusion 153 Introduction 185 An Introduction to CNS Depressants 185 CHAPTER 5 The History of CNS Depressants 186 The Effects of CNS Depressants: How and Why Drugs Work 157 Benefits and Risks 186 Types of CNS Depressants 188 Introduction 158 Benzodiazepines: Valium-Type Drugs 188 The Intended and Barbiturates 192 Unintended Effects of Drugs 158 Other CNS Depressants 194 vi ❚ Contents Patterns of Abuse with Alcohol Consumption CNS Depressants 198 in the United States 235 Treatment for Withdrawal 200 Current Statistics and Trends in Alcohol Consumption 237 Natural Depressants 201 Percentages of the Drinking Population: A Pyramid Model 238 Dual Problems: Underage CHAPTER 7 and Adult Drinking 239 Alcohol: Pharmacological Effects 206 Economic Costs of Alcohol Abuse 247 History of Alcohol in America 250 Introduction 207 Drinking Patterns 250 Historical Considerations 251 The Nature and History of Alcohol 207 Defining Alcoholics 254 Alcohol as a Drug 209 Cultural Differences 255 Alcohol as a Social Drug 209 Alcohol Abuse and Impact of Alcohol 210 Alcoholism Disorders 256 Alcohol and Crime 210 Types of Alcoholics 256 Alcohol and Cancer 211 Major Traditional Distinctions Alcopops 211 Between “Wet” and “Dry” Cultures 258 Drinking and College Students 211 Cultural Influences 259 Underage Drinking 212 Culture and Drinking Behavior 259 The Properties of Alcohol 213 Culture and Disinhibited Behavior 260 The Physical Effects of Alcohol 215 Culture Provides Rules Alcohol and Tolerance 217 for Drinking Behavior 261 Alcohol Metabolism 218 Culture Provides Ceremonial Polydrug Use 218 Meaning for Alcohol Use 261 Short-Term Effects 218 Culture Provides Models of Alcoholism 262 Dependence 220 Cultural Stereotypes of Drinking Alcohol and Genetics 221 May Be Misleading 262 Culture Provides Attitudes The Effects of Alcohol on Regarding Alcohol Consumption 263 Organ Systems and Bodily Functions 221 Culture Determines What Is Considered Brain and Nervous System 222 Acceptable Amounts of Drinking 263 Liver 223 College and University Digestive System 224 Students and Alcohol Use 264 Blood 224 Cardiovascular System 224 Binge Drinking 266 Sexual Organs 225 Gender and Collegiate Alcohol Use 267 Endocrine System 225 Alcohol Consumption Kidneys 226 Patterns of Women 268 Mental Disorders and The Role of Alcohol in Domestic Violence 270 Damage to the Brain 226 Alcohol and Sex 271 The Fetus 226 Alcohol and the Family: Destructive Gender Differences 227 Types of Social Support and Organizations Malnutrition 227 for Victims of Alcoholics 272 Codependency and Enabling 272 Children of Alcoholics (COAs) and CHAPTER 8 Adult Children of Alcoholics (ACOAs) 272 Alcohol: Behavioral Effects 233 Treatment of Alcoholism 273 Getting Through Withdrawal 274 Introduction 234 Helping the Alcoholic Family Recover 275 Contents ❚ vii Caffeine-Like Drugs (Xanthines) 348 CHAPTER 9 OTC Sympathomimetics 354 Herbal Stimulants 355 Narcotics (Opioids) 287 Global Stimulant Abuse 356 Stimulant Production 356 Introduction 288 Global Stimulant Consumption 356 What Are Narcotics? 288 Global Drug Policy 356 The History of Narcotics 289 Opium in China 289 CHAPTER 11 American Opium Use 290 Tobacco 366 Pharmacological Effects 292 Narcotic Analgesics 292 Other Therapeutic Uses 293 Tobacco Use: Scope of the Problem 367 Abuse of Prescription Opioid Painkillers 294 Current Tobacco Use in the United States 367 Mechanisms of Action 295 Cigarette Smoking: A Costly Addiction 367 Side Effects 295 The History of Tobacco Use 368 Abuse, Tolerance, Popularity in the Western World 369 Dependence, and Withdrawal 296 History of Tobacco Use in America 369 Heroin Abuse 296 Tobacco Production 370 Treatment of Heroin and Government Regulation 371 Other Narcotic Dependence 303 Pharmacology of Nicotine 372 Other Narcotics 305 Effects of Nicotine on the Morphine 305 Central Nervous System 373 Methadone 306 Other Effects of Nicotine 373 Fentanyls 307 Cigarette Smoking 373 Hydromorphone 308 Cardiovascular Disease 373 Oxycodone 308 Cancer 373 Meperidine 308 Bronchopulmonary Disease 373 Hydrocodone 308 Effects on Pregnancy 373 Buprenorphine 308 MPTP: A “Designer” Tragedy 309 “Light” Cigarettes 374 Codeine 309 Electronic Cigarettes 375 Pentazocine 310 Tobacco Use and Exposure Tramadol 310 Without Smoking 375 Narcotic-Related Drugs 310 Smokeless Tobacco 375 Dextromethorphan 310 Secondhand Smoke 375 Clonidine 311 Reasons for Smoking Naloxone/Naltrexone 312 and the Motivation to Quit 376 Natural Narcotic Substances 312 Reasons for Smoking 376 Benefits of Cessation 377 The Motivation to Quit 377 CHAPTER 10 Smoking Prohibition Stimulants 320 Versus Smokers’ Rights 378 Introduction 321 CHAPTER 12 Major Stimulants 321 Amphetamines 321 Hallucinogens (Psychedelics) 383 Cocaine 337 Minor Stimulants 348 Introduction 384 viii ❚ Contents The History of Hallucinogen Use 384 Therapeutic Uses and the Controversy The Native American Church 385 over Medical Marijuana Use 444 Timothy Leary and the League Reduction in Intraocular (Eye) of Spiritual Discovery 386 Pressure 446 Hallucinogen Use Today 386 Cancer 446 Antiasthmatic Effect 448 The Nature of Hallucinogens 386 Muscle-Relaxant Effect 448 Sensory and Psychological Effects 387 Antiseizure Effect 448 Mechanisms of Action 389 Antidepressant Effect 448 Types of Hallucinogenic Agents 389 Analgesic Effect 448 Traditional Hallucinogens: LSD Types 390 Antinauseant 448 Phenylethylamine Hallucinogens 398 Appetite Stimulant 449 Anticholinergic Hallucinogens 401 Short-Term Consequences Other Hallucinogens 403 of Smoking Marijuana 449 Natural Substances 407 Long-Term Consequences Naturally Occurring Hallucinogens 407 of Smoking Marijuana 449 Salvia divinorum 408 The Physiological Effects of Marijuana Use 450 Effects on the Brain 450 CHAPTER 13 Effects on the Central Nervous System 451 Effects on the Respiratory System: Marijuana 416 Smoking Marijuana 451 Effects on the Respiratory System: Introduction 417 Vaporizing Marijuana 452 Marijuana: History and Effects on the Cardiovascular System 452 Effects on Sexual Current Trends 421 Performance and Reproduction 453 Historical Roots of Marijuana 421 Tolerance and Dependence 454 Current Use of Marijuana 424 Chronic Use 454 Recent Trends in Use of Marijuana: 8th, 10th, and 12th Graders 425 Marijuana: Is It the CHAPTER 14 Assassin of Youth? 429 Inhalants 467 Major Factors Affecting Marijuana Use 429 Is Marijuana Really Introduction 468 a Gateway Drug? 431 History of Inhalants 468 Misperceptions of Marijuana Use 432 Types of Inhalants 469 Characteristics of Cannabis 432 Volatile Substances 469 Synthetic Marijuana 435 Anesthetics 470 Trends in Use 436 Nitrites 471 Perceived Risk 436 Legislation 471 The Behavioral Effects Current Patterns and Signs of Abuse 471 of Marijuana Use 436 Adolescent and Teenage Usage 472 The “High” 436 Gender, Race, Socioeconomics, Subjective Euphoric Effects 438 and Abuse 472 Driving Performance 440 Signs of Inhalant Abuse 472 Critical-Thinking Skills 442 Amotivational Syndrome 443 Dangers of Inhalant Abuse 473 Contents ❚ ix Drug Use Among Adolescents 547 CHAPTER 15 Consequences of Underage Drug Use 549 Why Adolescents Use Drugs 550 Over-the-Counter, Patterns of Drug Use in Prescription, and Herbal Drugs 476 Families of Adolescents 551 Noteworthy Findings Regarding Teen Drug Use 552 Introduction 477 Adolescent Versus Adult Drug Abuse 555 OTC Drugs 477 Consequences and Coincidental Problems 556 Abuse of OTC Drugs 478 Prevention, Intervention, and Treatment Federal Regulation of OTC Drugs 479 of Adolescent Drug Problems 560 OTC Drugs and Self-Care 479 Summary of Adolescent Drug Abuse 562 Types of OTC Drugs 480 Drug Use Among College Students 562 OTC Herbal (Natural) Products 491 Reasons for College Students’ Drug Use 564 Prescription Drugs 494 Additional Noteworthy Findings Regarding Prescription Drug Abuse 494 Drug Use by College Students 567 Prescription Abuse and Pregnancy 497 Recommendations for Reducing Drug Necessary Drug Information Use and Abuse on College Campuses 570 for Healthcare Providers 497 HIV and AIDS 570 Drug Selection: Generic Major U.S. Statistics and Trends in Specific Versus Proprietary 500 Populations Living with HIV/AIDS 571 Common Categories The Nature of HIV Infection of Prescription Drugs 501 and Related Symptoms 572 Common Principles of Drug Use 508 Diagnosis and Treatment 574 Who Is at Risk for AIDS? 577 Women and Men Acquiring CHAPTER 16 HIV and Drugs of Abuse 578 Youth and HIV/AIDS 580 Drug Use in Subcultures What to Do About HIV and AIDS 582 of Special Populations 519 The Entertainment Industry and Drug Use 582 Introduction 520 Promoter of Drug Use: The Internet 585 Athletes and Drug Abuse 521 Social Networking Motivating Drug Use 586 Laws Intended to Stop the Use of The Dark Web: The Place to Go to Performance-Enhancing Drugs Anonymously Purchase Illicit Drugs? 586 in Professional Sports 525 Drugs Used by Athletes 525 Prevention of Abuse 537 CHAPTER 17 Drug Use Among Women 538 Drug Abuse Prevention 603 Women Are More Concerned About Drug Use Than Men 538 Patterns of Drug Use: Comparing Introduction 604 Females with Males 539 How Serious Are the Problems Female Roles, Seeking of Substance Use Disorders? 606 Treatment, and Drug Addiction 541 Women’s Responses to Drugs 543 Drug Prevention 609 Treatment of Drug Risk Factors and Protective Factors 609 Dependence in Women 546 Prevention of Drug Considering the Audience Dependence in Women 547 and Approach 610

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