drosophila

458 Pages·2011·1.87 MB·English

Abstracts of papers presented
at the 2011 meeting on
NEUROBIOLOGY OF
DROSOPHILA

October 3–October 7, 2011

Cold Spring Harbor Laboratory
Cold Spring Harbor, New York
Abstracts of papers presented
at the 2011 meeting on
NEUROBIOLOGY OF
DROSOPHILA

October 3–October 7, 2011

Arranged by

Claude Desplan, New York University
Nancy Bonini, University of Pennsylvania / HHMI

Cold Spring Harbor Laboratory
Cold Spring Harbor, New York
This meeting was funded in part by the National Institute of
Neurological Disorders and Stroke, and the Eunice Kennedy
Shriver National Institute for Child Health and Human
Development, branches of the National Institutes of Health; and the
National Science Foundation.

Contributions from the following companies provide core support for the
Cold Spring Harbor meetings program.

Corporate Sponsors
Agilent Technologies
Astellas-OSI Oncology
AstraZeneca
BioVentures, Inc.
Bristol-Myers Squibb Company
Genentech, Inc.
GlaxoSmithKline
Life Technologies (Invitrogen & Applied Biosystems)
New England BioLabs, Inc.
Sanofi-Aventis

Plant Corporate Associates

Monsanto Company
Pioneer Hi-Bred International, Inc.

Foundations

Hudson-Alpha Institute for Biotechnology

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Front cover: Neurons in the developing medulla part of the optic lobe
express different combinations of three transcription factors labeled in red
(Apterous), green (Toy) and blue (Drifter). Courtesy of Xin Li (NYU).

Back cover: Heterogeneous neuronal cell clones in the adult medulla
obtained with Twin Spot MARCM. Courtesy of Alberto DelValle (NYU).
NEUROBIOLOGY OF DROSOPHILA
Monday, October 3 – Friday, October 7, 2011

Monday 7:30 pm 1 Sensory Systems

Monday 9:30 pm Keynote Speaker

Tuesday 9:00 am 2 Behavior, Brain Function and its
Evolution

Tuesday 2:00 pm 3 Poster Session I

Tuesday 4:30 pm Wine and Cheese Party *

Tuesday 7:00 pm 4 Neural Circuit: Development, Evolution &
Function

Tuesday 9:00 pm Elkins Memorial Lecture

Wednesday 9:00 am 5 Neurological Disease Models and
Cellular Mechanisms

Wednesday 2:00 pm 6 Poster Session II

Wednesday 7:00 pm 7 Brain Development and Function

Wednesday 9:00 pm Benzer Lecture

Thursday 9:00 am 8 Synaptic Transmission, Development
and Plasticity

Thursday 1:00 pm 9 Poster Session III

Thursday 3:00 pm 10 Neural Development and Evolution

Thursday 7:00 pm Banquet

Friday 9:00 am 11 Technological Innovations and
Applications

Poster sessions are located in Bush Lecture Hall
* Airslie Lawn, weather permitting
Mealtimes at Blackford Hall are as follows:
Breakfast 7:30 am-9:00 am
Lunch 11:30 am-1:30 pm
Dinner 5:30 pm-7:00 pm

Bar is open from 5:00 pm until late
Abstracts are the responsibility of the author(s) and publication of an
abstract does not imply endorsement by Cold Spring Harbor Laboratory of
the studies reported in the abstract.

These abstracts should not be cited in bibliographies. Material herein
should be treated as personal communications and should be cited as
such only with the consent of the author.

Please note that recording of oral sessions by audio, video or still
photography is strictly prohibited except with the advance permission of
the author(s), the organizers, and Cold Spring Harbor Laboratory.

Printed on 100% recycled paper.
PROGRAM

MONDAY, October 3—7:30 PM

SESSION 1 SENSORY SYSTEMS

Chairperson: T. Clandinin, Stanford University, California

TRPA1 isoform diversity uncouples chemical nociception from
thermosensation in Drosophila
KyeongJin Kang, Vincent C. Panzano, Elaine C. Chang, Lina Ni, Marc
Muskavitch, Paul A. Garrity.
Presenter affiliation: National Center for Behavioral Genomics,
Brandeis University, Waltham, Massachusetts. 1

Gustatory perception is required for diet-dependent sleep
fragmentation but not energy storage
Nancy J. Linford, Tammy P. Chan, Scott D. Pletcher.
Presenter affiliation: University of Michigan, Ann Arbor, Michigan. 2

Modulation of visual processing by flight in Drosophila
Gaby Maimon.
Presenter affiliation: The Rockefeller University, New York, New York. 3

Conserved determinants of pain perception
Graham G. Neely, Paul A. Garrity, Clifford J. Woolf, Josef M.
Penninger.
Presenter affiliation: Garvan Institute of Medical Research, Sydney,
Australia; Institute of Molecular Biotechnology of the Austrian Academy
of Sciences, Vienna, Austria. 4

Taste-independent Detection of Sugar in Drosophila
Monica Dus, Soohong Min, Alex C. Keene, Greg S. Suh.
Presenter affiliation: Skirball institute, NYU School of Medicine, New
York, New York. 5

Temporal aspect of odor stimuli and its role in odor coding
Carlotta Martelli, John R. Carlson, Thierry Emonet.
Presenter affiliation: Yale University, New Haven, Connecticut. 6

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A new Prospero and microRNA-279 pathway restricts CO
2
receptor neuron formation
Marion Hartl, Laura F. Loschek, Daniel Stephan, K. P. Siju, Christiane
Knappmeyer, Ilona C. Grunwald Kadow.
Presenter affiliation: Max-Planck Institute for Neurobiology, Munich,
Germany. 7

A map of auditory pathways in the Drosophila brain
Jason S. Lai, Shyn-Jie Lou, Barry J. Dickson, Ann-Shyn Chiang.
Presenter affiliation: Institute of Biotechnology, Hsinchu, Taiwan. 8

MONDAY, October 3—9:30 PM

KEYNOTE SPEAKER

Rüdiger Wehner
University of Zürich, Switzerland
“Beyond Drosophila—Maps in insect minds?” 9

TUESDAY, October 4—9:00 AM

SESSION 2 BEHAVIOR, BRAIN FUNCTION AND ITS EVOLUTION

Chairperson: K. Scott, University of California, Berkeley

Generation of rhythmic motor patterns
Elizabeth Heckscher, Jourdain Roberts, Ryan Kersh, Katherine
Reinhart, Shawn Lockery, Chris Doe.
Presenter affiliation: University of Oregon, Eugene, Oregon. 10

The elements of fruit fly walking behavior
Jamey S. Kain, Sean M. Buchanan, Benjamin L. de Bivort.
Presenter affiliation: Harvard University, Cambridge, Massachusetts. 11

Winging it—The genetic basis of wing rowing in Drosophila
yakuba and Drosophila santomea male courtship
Jessica D. Cande, David Stern, Benjamin Prudhomme, Nicolas
Gompel.
Presenter affiliation: CNRS, Marseille, France. 12
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Flies actively track attractive odors and anti-track aversive odors
with a single sign-switchable flight control algorithm
Mark Frye, Sara Wasserman.
Presenter affiliation: Howard Hughes Medical Institute, UCLA, Los
Angeles, California. 13

Sleep and arousal regulation by dopamine in Drosophila
melanogaster
Kazuhiko Kume, Taro Ueno, Kazuhiro Takahama, Jun Tomita.
Presenter affiliation: Kumamoto University, Kumamoto, Japan. 14

Mechanisms underlying the loss of sleep in Drosophila sleepless
mutants
Wen-Feng Chen, Mallory Sowcik, Sarah Maguire, Paul Kosterin, Ana
Lía Obaid, Brian M. Salzberg, Amita Sehgal.
Presenter affiliation: Howard Hughes Medical Institute, University of
Pennsylvania School of Medicine, Philadelphia, Pennsylvania. 15

Juvenile hormone modulates the maturation of female receptivity
in Drosophila melanogaster
Julide Bilen, Lynn M. Riddiford.
Presenter affiliation: Howard Hughes Medical Institute, Ashburn,
Virginia. 16

Neurons governing copulation timing in male Drosophila
Michael A. Crickmore, Leslie B. Vosshall.
Presenter affiliation: The Rockefeller University, New York, New York. 17

Drosophila show context-dependent light aversion during egg-
laying site selection
Rebecca C. Yang, Ananya Guntur, Edward Zhu, Ulrich Stern.
Presenter affiliation: Duke University, Durham, North Carolina. 18

Remembering sweetness and nutrient value of sugar in
Drosophila
Christopher J. Burke, Wolf Huetteroth, Scott Waddell.
Presenter affiliation: UMass Medical School, Worcester,
Massachusetts. 19

DPP signaling contributes to set basic properties of the PDF
circuit in Drosophila
Esteban J. Beckwith, Jimena Berni, María F. Ceriani.
Presenter affiliation: Fundación Instituto Leloir, Buenos Aires,
Argentina. 20

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TUESDAY, October 4—2:00 PM

SESSION 3 POSTER SESSION I

The circuit principles of neuronal processing in larval Drosophila
melanogaster phototaxis
Bruno Afonso, Marc Gershow, Elizabeth A. Kane, Aravi Samuel.
Presenter affiliation: Harvard University, Cambridge, Massachusetts. 21

Molecular, cellular and circuit basis of acid sensing by the
Drosophila olfactory system
Minrong Ai, Soohong Min, Yael Grosjean, Richard Benton, Greg Suh.
Presenter affiliation: Skirball Institute, NYU Medical Center, New York,
New York. 22

Pathogenic Huntington induces synaptic morphology defects by
disrupting local BMP signaling
Yulia Akbergenova, J. Troy Littleton.
Presenter affiliation: MIT, Cambridge, Massachusetts. 23

Identifying monoaminergic neurons that mediate aggression in
Drosophila
Olga V. Alekseyenko, Yick-Bun Chan, Ran Li, Edward A. Kravitz.
Presenter affiliation: Harvard Medical School, Boston, Massachusetts. 24

Neuroepithelial specification and distinct modes of neuroblast
formation in the Drosophila optic lobe
Holger Apitz, Iris Salecker.
Presenter affiliation: MRC National Institute for Medical Research,
London, United Kingdom. 25

Neuropeptide modulation of fly aggressive behavior
Kenta Asahina, Timothy D. Tayler, Anne C. Hergarden, David J.
Anderson.
Presenter affiliation: Howard Hughes Medical Institute, California
Institute of Technology, Pasadena, California. 26

Differential effects of dlg isoforms in synaptic transmission and
short-term plasticity
César Astorga, Ramón Jorquera, Ricardo Delgado, Jimena Sierralta.
Presenter affiliation: Universidad de Chile, Santiago, Chile. 27

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Concerted control of gliogenesis by insulin receptor/TOR and
FGF signalling in the post-embryonic brain
Amelie Avet-Rochex, Aamna K. Kaul, Ariana Gatt, Helen McNeill,
Joseph M. Bateman.
Presenter affiliation: King's College London, London, United Kingdom. 28

Temporal patterning in transit-amplifying neural progenitors
Omer A. Bayraktar, Chris Q. Doe.
Presenter affiliation: Howard Hughes Medical Institute, University of
Oregon, Eugene. 29

Understanding EB1-dependent microtubule regulation essential
for axon growth
Robin Beaven, Natalia Sánchez-Soriano, Juliana Da Silva, Koen
Venken, Hugo Bellen, Hiro Ohkura, Andreas Prokop.
Presenter affiliation: University of Manchester, Manchester, United
Kingdom. 30

A non-thermosensory isoform of Drosophila melanogaster TRPA1
is required for thermal nociception
Lixian Zhong, Andrew Bellemer, Ken Honjo, Richard Y. Hwang, W.
Daniel Tracey.
Presenter affiliation: Duke University Medical Center, Durham, North
Carolina. 31

Neuronal function of dOCRL, a gene implicated in endosomal
traffic and Lowe’s syndrome
Sarah A. Biber, Agata N. Becalska, Avital A. Rodal.
Presenter affiliation: Brandeis University, Waltham, Massachusetts. 32

Control of neuronal cell fate and numbers by integration of
distinct daughter cell proliferation modes with temporal
progression
Caroline Bivik, Carina Ulvklo, Ryan MacDonald, Magnus Baumgardt,
Daniel Karlsson, Stefan Thor.
Presenter affiliation: Linkoping University, Linkoping, Sweden. 33

Mutations in postsynaptic actin alter presynaptic active zone
organization and synaptic growth
Aline D. Blunk, Yulia Akbergenova, Richard W. Cho, Jihye Lee, J. Troy
Littleton.
Presenter affiliation: Massachusetts Institute of Technology,
Cambridge, Massachusetts. 34

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