Dr. Atul Arun Kulkarni The Director In Charge Jankalyan Raktapedhi Pune

19 Pages·2017·1.46 MB·English

Dr. Atul Arun Kulkarni
The Director In Charge
Jankalyan Raktapedhi
Pune
NAT in India: Where we Stand
Dr. Atul Kulkarni
Director & In-charge
Jankalyan Raktpedhi
Pune
Significance of Blood Bank
In the recent wave of Demonetisation,
A Friend asked me if any Bank was
open????
I said YES
BLOOD BANK
Evolution of Blood Banking
NAT
Journey to Safe Blood
Emerging and Re-Emerging Blood Screening Technologies
Chagas
HBV NAT
WNV
HIV HCV NAT
HIV Ag
Anti-HCV
Anti-HTLV
ALT
Anti-HBc
Anti-CMV
Anti-HIV
HBsAg
Syphilis
1938
1970 1975 1980 1985 1990 1995 2000 2005 2010
 Globally, every year 16 M new HBV, 5 M new HCV & 160,000 new HIV infections are estimated due
to unsafe blood transfusions
 Compared to 30 years ago, worldwide TTI risk has decreased significantly
 Active screening, improved technologies and hemovigilance programs are have impacted the rate
of TTIs
Source: 1. BihlF, et al. Transfusion Transmitted Infections. J TranslMed. 2007;5:25.
2. WHO Screening Donated Blood from Transfusion Transmissible Infections: Recommendations. World Health Organization. 2010.
Editorial. Improving Blood Safety Worldwide. Lancet. 2007:370(9603):1879-1974
Introduction of NAT - Globally
Since 1997
International survey on NAT testing of blood donations: expanding implementation and yield from 1999 to 2009, VoxSanguinis2012.
Implementation of NAT- Globally
~53 million units of blood are screened with NAT
100% NAT implementation
Partial NAT implementation
1. Australia
1. Brazil
2. Singapore
2. Czech Republic
3. Germany
3. Taiwan
4. New Zealand
4. China
5. Slovenia
5. Lithuania
6. Canada
6. India
7. Switzerland
7. Serbia
8. Finland
8. Spain
9. Japan
9. Greece
10. United States
10. Thailand
11. Portugal
11. Estonia
12. Austria
12. Korea
13. Netherlands
13. Ukraine
14. Hong Kong
14. Malaysia
15. Belgium
15. Hungary
16. Norway
17. Poland
18. Italy
19. United Kingdom
20. France
Implementation of NAT - India
17 states,~60-70 BBs using Automated or Manual NAT platforms
Chandigarh – 1 BB
Uttarakhand : 1 BB
Punjab: 3 BBs
Haryana: 1 BBs Delhi: 15 BBs Assam: 1 BB
Rajasthan :4 BBs
Manipur: 1 BB
Gujarat:5 BBs
Uttar Pradesh: 03 BB
Maharashtra : 11 BBs West Bengal: 03 BB
Odisha: 4
AP: 03 BBs State Project 4 BBs serving to additional 2 large BBs
Karnataka:2
Telangana: 03 BBs
State Project 1 BB (serving to adjoining
40 small BBs on need basis) + 1
Kerala: 2 BBs Tamil Nadu: 03 BB
Statewise Access to NAT in India
6,39,654 Donations in 14 states await NAT facility
States having access to NAT States AWAITING access to NAT
Sr. State & No. of Blood Annual Blood No.ofNAT Sr. State Annual Blood
No Banks Donation sites
No Donations
1 Chandigarh –4 86029 1
1 J&K -22 18,820
2 Punjab -45 1,86,378 4
2 Himachal Pradesh -15 32,655
3 Haryana -21 1,50,969 1
3 Bihar -39 91,662
4 Rajasthan -49 3,79,376 4
4 Madhya Pradesh -61 2,37,447
5 Delhi -21 2,98,073 15
5 Chhattisgarh -16 61,261
6 Uttarakhand-19 92,300 1
6 Jharkhand -24 1,01,576
7 Uttar Pradesh -89 4,43,557 3
7 Sikkim -2 3,154
8 Assam -26 1,29,106 1
8 Meghalaya -5 11,017
9 Manipur -3 18,505 1
9 Arunachal Pradesh -8 5,195
10 West Bengal -62 5,74,800 3
10 Nagaland -8 8,136
11 Odisha -61 2,57,711 4
11 Mizoram -10 22,226
12 Gujarat -84 4,93,684 5
12 Tripura -6 6,910
13 Maharashtra -109 7,07,574 11
13 Goa -3 16,897
14 Karnataka -66 3,02,205 2
14 Puducherry –5 22,698
15 Kerala -45 2,43,792 2
Total 6,39,654
16 Andhra Pradesh + 4,04,693 3 +3
Telangana-112
Source: NACO FACTSHEET 2013-14
17 Tamil Nadu -94 3,42,550 3
NAT tested Blood in India
Only 10% NAT tested SAFE BLOOD
 Annually 8 M blood donations collected
 30 M transfusions of blood and blood
0.6 M
products
 Only ~60-70 BBs using Automated or
08 M manual NAT platforms
 Above primary centres providing services
to additional 60-70 small/large blood banks
 So total 120-140 BBs of the 2760 BBs in
India provide 100% or Partial NAT tested
Total donations collected Donations NAT screened
blood, accounting to ~0.6-0.8 M donations