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Doppler Ultrasound in Obstetrics and Gynecology Dev Maulik Christoph C. Lees Editors 123 Doppler Ultrasound in Obstetrics and Gynecology Dev Maulik • Christoph C. Lees Editors Doppler Ultrasound in Obstetrics and Gynecology Third Edition Editors Dev Maulik Christoph C. Lees Department of Obstetrics and Department of Metabolism, Digestion Gynecology and Reproduction University of Missouri–Kansas City Imperial College Healthcare NHS Trust Kansas City, MO, USA London, UK ISBN 978-3-031-06188-2 ISBN 978-3-031-06189-9 (eBook) https://doi.org/10.1007/978-3-031-06189-9 © Springer Nature Switzerland AG 2005, 2023 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland To my wife Shibani for sustaining me with her love, and giving me strength and inspiration for this long but worthy endeavor, and to our incredible grandchildren, Kiran, Sarit and Tara, for bringing sunshine into our lives. Dev Maulik To my wife Paula and sons Daniel and Rafael, for their love, enthusiasm and encouragement throughout the years that it has taken this book to grow, develop and finally be born. Christoph Lees Preface Almost two decades have passed since the publication of the second edition of the book. This relatively long interval has witnessed major innovations in the diagnostic Doppler sonography, a greater depth of knowledge on fetal and maternal cardiovascular physiology and pathology, and the emergence of new evidence for guiding clinical practice. In many areas of practice, the use of Doppler has become an essential pre-requisite to appropriate investigation and diagnosis. These advances have provided a powerful rationale for bring- ing the book up to date so that it may continue to serve our readers in the future. We have critically examined the information contained in the second edition, and comprehensively revised and expanded the contents as deemed appropriate. The process has been successfully concluded and we are very pleased to offer the third edition of “Doppler Ultrasound in Obstetrics and Gynecology” to our readers. This book has, accordingly, undergone a significant renewal. We take this opportunity to welcome the 35 new authors and co-authors who have sub- stantially contributed to enriching this edition by providing new chapters or rewriting and updating preexisting ones. We removed one chapter due to lack of any significant development and have added 17 new chapters. Some of these are combinations of several previous chapters and four present new areas of current research and clinical application. In this complex and extensive endeavor, we were greatly assisted by a dedicated team of internationally recognized experts who have generously and enthusiastically participated in this venture despite their enormous responsibilities and hectic schedules. But the overwhelming challenge we had to face and survive was the once in a century pandemic that overshad- owed almost everything that we had to do personally or professionally. Our deadlines had to shift several times. We are very grateful to Linda Franta, our highly skilled and dedicated editorial assistant, who organized the work schedule, continuously acted as the liaison between the editors, the authors and the publishing house of Springer. We remain appreciative of the success of the first two editions and hope that the third edition will be worthy of continuing enthusiastic reception. vii Contents 1 Doppler Sonography: A Brief History . . . . . . . . . . . . . . . . . . . . . 1 Dev Maulik 2 Physical Principles of Doppler Ultrasonography . . . . . . . . . . . . . 11 Dev Maulik 3 Spectral Doppler: Basic Principles and Instrumentation . . . . . . 21 Dev Maulik 4 Spectral Doppler Sonography: Waveform Analysis and Hemodynamic Interpretation . . . . . . . . . . . . . . . . . 39 Dev Maulik 5 Venous Hemodynamics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 Torvid Kiserud and Jörg Kessler 6 Doppler Color Flow: Basic Principles . . . . . . . . . . . . . . . . . . . . . . 81 Dev Maulik 7 Biosafety of Diagnostic Doppler Ultrasound . . . . . . . . . . . . . . . . 99 Kjell Å. Salvesen and Ragnar K. Sande 8 Fetal Cardiovascular Physiology . . . . . . . . . . . . . . . . . . . . . . . . . . 107 Dino A. Giussani, Kimberley J. Botting, Youguo Niu, Caroline J. Shaw, Sage G. Ford, and Avnesh S. Thakor 9 Maternal Cardiovascular Physiology and Assessment . . . . . . . . 123 Marc E. A. Spaanderman 10 Venous Doppler Sonography in Pregnancy . . . . . . . . . . . . . . . . . 131 Wilfried Gyselaers 11 Relationship Between Maternal and Fetal Cardiovascular Function . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145 Christoph C. Lees and Giulia Masini 12 Intrauterine Blood Flow and Postnatal Development . . . . . . . . . 153 David Ley and Karel Maršál 13 Fetal Renal Artery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 181 Stephen Contag ix x Contents 14 Umbilical Doppler Velocimetry: Normative Data and Diagnostic Efficacy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197 Dev Maulik, Tabitha Schrufer-Poland, and Emily M. Williams 15 Fetal Aortic Isthmus and Descending Aorta . . . . . . . . . . . . . . . . . 213 Karel Maršál and Edgar Hernandez-Andrade 16 The Cerebroplacental Ratio and Hypoxic Index in the Prediction of Fetal Outcome . . . . . . . . . . . . . . . . . . . 243 Philippe Arbeille, Gabriel Carles, Gustavo Vilchez, and Dev Maulik 17 The Cerebroplacental Ratio . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279 Edgar Hernandez Andrade and Eleazar Soto 18 Cerebral Blood Flow Velocity Waveforms and Fetal Anemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297 Jennifer J. Barr and Giancarlo Mari 19 First- and Second-Trimester Doppler Velocimetry of the Uteroplacental Circulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 313 Victoria Mumford and Asma Khalil 20 Uterine Doppler Velocimetry and Hypertensive Disease . . . . . . . 327 Tiziana Frusca, Andrea Dall’Asta, and Elvira Di Pasquo 21 Fetal Doppler Velocimetry in Monochorionic Pregnancy: Twin Reversed Arterial Perfusion, Twin- to- Twin Transfusion Syndrome, and Twin Anemia Polycythemia Sequence . . . . . . . . 337 Lee Na Tan, Fionnuala Mone, and Mark D. Kilby 22 Doppler Sonography in Pregnancies Complicated by Pre-gestational Diabetes Mellitus . . . . . . . . . . . 357 Gustavo Vilchez and Dev Maulik 23 Doppler Velocimetry in Prolonged Pregnancy . . . . . . . . . . . . . . . 371 Richard Bronsteen, Ali Alhousseini, and Ray Bahado-Singh 24 Umbilical Artery Doppler for Fetal Surveillance: Diagnostic Efficacy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 389 Dev Maulik and Tara Daming 25 Absent End-Diastolic Velocity in the Umbilical Artery and Its Clinical Significance . . . . . . . . . . . . . . . . . . . . . . . 399 Dev Maulik and Tabitha Schrufer-Poland 26 Fetal Doppler Velocimetry in High- Risk Pregnancies: Randomized Clinical Trials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417 Christoph C. Lees and T. Stampalija 27 Doppler Interrogation of the Umbilical Venous Flow . . . . . . . . . 437 Enrico Ferrazzi, Daniela Di Martino, and Tamara Stampalija 28 The Ductus Venosus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449 Torvid Kiserud and Jörg Kessler Contents xi 29 Doppler Examination of the Fetal Pulmonary Venous Circulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 475 Jay D. Pruetz, Jodie K. Votava-Smith, and Shuo Wang 30 Introduction to Fetal Doppler Echocardiography . . . . . . . . . . . . 499 Dev Maulik and Sarah Hostetter 31 Fetal Echocardiography to Plan Postnatal Management in Fetuses with Congenital Heart Disease . . . . . . . 521 Shivani M. Bhatt and Mary T. Donofrio 32 Doppler Echocardiography of Fetal Cardiac Arrhythmias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537 Varsha Thakur and Edgar Jaeggi 33 4D Fetal Doppler Echocardiography . . . . . . . . . . . . . . . . . . . . . . 559 Greggory R. DeVore 34 Cardiac Function in Fetal Growth Restriction . . . . . . . . . . . . . . 575 Giuseppe Rizzo, Ilenia Mappa, Victoria Bitsadze, Jamilya Khizroeva, Alexander Makatsarya, and Domenico Arduini 35 Role of Ultrasonography in Placenta Accreta Spectrum . . . . . . . 587 Marcus J. Rijken, Rozi Aditya Aryananda, and Sally Collins 36 Three-Dimensional Doppler Ultrasound in Gynecology . . . . . . . 599 Mark Hiraoka and Ivica Zalud 37 Doppler Ultrasound in Early Pregnancy Including Miscarriage, Ectopic Pregnancy, and Implantation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 615 Mercedes Espada Vaquero, Mathew Leonardi, and George Condous 38 Doppler in Benign and Malignant Conditions of the Ovary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 623 Andrea Day and Davor Jurkovic 39 Doppler in Benign and Malignant Conditions of the Uterus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 639 Thierry Van den Bosch 1 Doppler Sonography: A Brief History Dev Maulik 1.1 Introduction 1.2 C hristian Andreas Doppler and the Doppler Theory The origins of modern medical technology may be traced to nineteenth century Europe, when the 1.2.1 E arly Life industrial revolution ushered in sweeping changes in every aspect of life. Of all the momentous dis- The phenomenon bears the name of its discov- coveries and inventions of this period, there was erer, Christian Andreas Doppler, an Austrian one relatively obscure scientific event that laid mathematician and physicist (Fig. 1.1), born to the foundation for the subsequent development of Doppler technologies in the twelfth century—the discovery of a natural phenomenon that came to be known as the Doppler effect. Another critical event was the discovery of the piezoelectric phe- nomenon by Pierre Curie and Jacques Curie, which enabled the development of ultrasonic transducers many decades later. This chapter briefly describes the origin of the Doppler theory during the nineteenth century, traces the develop- ment of diagnostic Doppler ultrasound technol- ogy, and its pioneering applications in obstetrics and gynecology. Fig. 1.1 Christian Andreas Doppler. The oil painting was D. Maulik (*) done by an unidentified artist probably at the time of Department of Obstetrics and Gynecology, UMKC Doppler’s marriage in 1836. The original is in the Austrian School of Medicine/Truman Medical Center, UMKC Academy of Sciences to which it was donated by Mathilda School of Medicine, Kansas City, MO, USA von Flugl, the great granddaughter of Christian Doppler. e-mail: [email protected] (Reprinted from [1], with permission) © Springer Nature Switzerland AG 2023 1 D. Maulik, C. C. Lees (eds.), Doppler Ultrasound in Obstetrics and Gynecology, https://doi.org/10.1007/978-3-031-06189-9_1

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