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Kuzu Capstone Does acupuncture, Chinese herbal medicine and nutrition provide an effective modality to reducing fibroids? By Elif Kuzu A capstone project Presented in partial fulfillment of the requirements for the Doctor of Acupuncture and Oriental Medicine Degree Yo San University Los Angeles, California April 2017 1 Acknowledgements The author would like to express her gratitud e to the following people, without whose guidance and support this capstone would not have been possible: Dr. Harly Ramsey, Dr. Laraine Crampton, Dr. Andrea Murchison, Dr. Julie Hong, and Dr. Qian. Thank you for putting up with me! 2 Approvals Signatures Page This Capstone Project has bee n reviewed and approved by: 3 Abstract Uterine fibroids are the most widely recognized gynecologic tumors in women of conceptive age yet the etiology and pathogenesis of these injuries remain inadequately understood. Age, African ancestry, nulliparity and obesity have been recognized as inclining elements for uterine fibroids. Symptomatic tumors can bring about over the top uterine bleeding, heavy menstrual cycles and pelvic agony, and in addition related reproductive disorders, for example, infertility, miscarriage and other unfriendly pregnancy outcomes. Presently, there are restricted noninvasive and invasive treatments for fibroids and no early mediation or counteractive action techniques are promptly accessible. This literature review abridges the advances in translational uterine fibroid examine, not with standing present and proposed ways to deal with clinical administration but also to examine diet, acupuncture, Chinese herbal medicine as a modality to reduce or even dissolve the fibroid completely. As a result we find that diet, acupuncture and Chinese herbal medicine can significantly reduce and sometimes completely resolve the uterine fibroids depending on the size and time frame the patient had been diagnosed. Due to limited research on alternative modalities, it is hard to prove these nutrition therapies, acupuncture and Chinese herbal formulas work consistently, as the research needs to be broadens and the length of time for the research also need to be further evaluated. The longer and larger trails of woman presenting with uterine 4 fibroids on a combination diet control, acupuncture and Chinese herbal formulas can give us further advancements and insight on preventing and even completely eliminating this condition. 5 Table of Contents CHAPTER 1: Introduction ...................................................................................................................8 WWhhearte a Freib Urotiedrsi ncea nF idbervoeildosp………………………………………………………………………………………………………………………………….98 Signs and Symptoms of Fibroids………………………………………………...10 Definition of terms……………………………………………………………….12 CHAPTER 2: Review of Literature Chinese Medicine Interpretatio..n.. .o...f.. .T...h..e.. ..U...t.e...r.u...s..…....….....….....….....….....….....….....….....…....….....….....….....…......1155 Chinese Medical Theory of Abdominal Masses, such as Fibroids………………15 TCM Etiology and Pathogenesis………………………………………………………………..18 TCM Differentiation and Treatment………………………………………………………….20 TCM Ju Syndrome (Qi Masses)………………………………………………………………….21 TCM Liver Qi Stagnation…………………………………………………………………………..21 TCM Retention of Food and Phlegm………………………………………………………….22 TCM Ji Syndromes (Blood-Stasis Masses)………………………………………………….23 TCM Beginning Stage: Qi and Blood Stagnation…………………………………………23 TCM Center Stage: Retention of Stagnant Blood………………………………………..24 TCM Last Stage: Anti-Pathogenic Qi Deficiency and Blood Stasis………………..25 TCM Herbs and Herbal Formulas……………………………………………………………...27 TCM Acupuncture Points………………………………………………………………………….33 Diet and Nutrition……………………………………………………………………………………35 6 CHAPTER 3: Methodology ................................................................................................................40 General Statement of Methodology…………………………………………………………..40 Sampling Procedures………………………………………………………………………………40 Data Analysis…………………………………………………………………………………………..41 CHAPTHEuRm 4a: nR Reseuseltasrch Ethical Considerations………………………………………………….42 …………………………………………………………………………………………43 Chinese Herbal Formulas Studies…………………………………………………………….43 Acupuncture Point Studies………………………………………………………………………47 CHAPTSEtRud 5ie: sD oisnc Dusiesti oannd Nutrition…………………………………………………………………..48 REFERENCES ……………………………………………………………………………………50 …………………………………………………………………………………………………….53 APPENDICES IRB Approval Letter 7 Ch.1 Introduction Although uterine fibroids are typically treated by western medicine, the benefits of eastern medicine have started to arise. New developing research to therapy is allowing women to examine their treatment options. There are many resources that prove the positive effects of Chinese medicine treatment dealing with uterine fibroids. The holistic practice in Oriental medicine allows the patient to not only be examined by one method but by several different methods. The interconnectedness of evaluating the whole body instead of symptom or disease is not only offering various answers to the causes of uterine fibroids but also treating the fibroids effectively. In this research paper, I will begin by briefly discussing the western medicine symptoms and treatments, and then thoroughly examining eastern medicine therapies and approaches such as acupuncture, acupuncture points, Chinese herbal medicine, and nutrition. Uterine fibroids also known as myoma, leiomyoma, and fibromyoma are one of the most common pelvic tumors. The cause is unknown according to several sources such as Oxford Journal of Human Reproduction and Harvard Women’s Health Watch. Although, no one really knows what causes fibroids, genes that accelerate the growth of uterine muscle cells may have a part and/or abnormalities of the uterine vessels may be involved as well. Estrogen and progesterone might be an important tool in the presence of fibroids because fibroids seldom occur before first menstrual period, pregnancy can spur their growth, and the fibroids usually shrink after menopause (Harvard Health Publication, 2008). 8 Most women develop uterine fibroids after the age of 30 or during their childbearing years according to Medline Plus. Uterine Fibroids can develop in early age although it is rare (Yi and Li-xing, 2008). African American women are three times more likely to develop symptomatic fibroids than women of other ethnic groups, and typically at an earlier age (Harvard Health Publication, 2008), (African Health Science, 2011). Where fibroids develop: Fibroids can develop in several different areas of the uterus. According to “Gynecology in Practice” there are four different areas uterine fibroids can develop. One area is myometrial; this is located in the muscle wall of the uterus. Myometrial leiomyoma’s can be further divided into intramural fibroids (which occupy approximately 60-70% of all uterine fibroids) (Yi and Li-xing, 2008). Another area is submucosal which is underneath the uterine lining. The submucosal fibroids occupy roughly 10% (Yi and Li-xing, 2008). The last two areas that can be affected are subserosal which is under the outside covering of the uterus and occupy about 20-30% and lastly the pendunculated which is located either on a long stalk on the outside of the uterus or inside the cavity of the uterus (Warshowsky, 2010). Uterine fibroids can show up singular, but most often are of multiple types (Yi and Li-xing, 2008). Yi and Li-xing in their book “The Clinical Practice of Chinese Medicine Endometriosis & Uterine Fibroids” also add that Uterine Fibroids sometimes can be detected in the uterine cervix called cervix leiomyoma’s. 9 Signs and Symptoms of Fibroids: Although cervix fibroids are benign they do cause several different symptoms that may affect one’s everyday health and life. “However a large number of patients are asymptomatic and not only till one has a pelvic exam do patient realize that they may have a uterine fibroid. The clinical manifestations of uterine fibroids vary in regards to location, size, rate of growth and the number of complications due to secondary degeneration” (Yi and Li-xing, 2008). Medline Plus states that, the most common symptoms are gas, abdominal fullness, constipation, bleeding between periods, menorrhagia, periods that may last longer, pressure in the lower abdomen, increase in urinary frequency and pain during intercourse” (Medline Plus, 2010). Fibroids can radically modify a woman’s personal satisfaction. For instance, a substantial fibroid can grow the uterus to the span of a trimester pregnancy and press against the gut or bladder, bringing about clogging or incessant pee. Fibroids are likewise once in a while connected with barrenness, unnatural birth cycle, and untimely work. Be that as it may, the most well-known grumbling is substantial, frequently cluster studded menstrual dying, called menorrhagia (if a cushion or tampon is drenched as the hour progressed) or hypermenorrhagia (if at least two tampons or cushions are splashed as the hour progressed), which can make a lady a virtual detainee in her home amid her periods. Such substantial draining can likewise bring about iron-inadequacy weakness (PubMed Health, 2014). Hard Uterine masses in Chinese Medicine are referred to as concretions and conglomerations (Yi and Li-xing, 2008). “The etiologies of these conditions are generally 10

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A capstone project Presented in partial fulfillment of the requirements for the. Doctor of Acupuncture and Oriental Medicine Degree. Yo San University.
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