Diuretic Agents: Clinical Physiology and Pharmacology PDF
Preview Diuretic Agents: Clinical Physiology and Pharmacology
Diuretic Agents The Dropsical Woman (La Femme Hydropique) by Gerard Dou (1613-1675) (Louvre, Paris, reprinted with permission). Diuretic Agents Clinical Physiology and Pharmacology Edited by Donald Seldin Department of Internal Medicine Southwestern Medical School University of Texas Dallas, Texas and Gerhard Giebisch Department of Cellular and Molecular Ph-ysiology Yale University School of Medicine New Haven, Connecticut ACADEMIC PRESS San Diego London Boston New York Sydney Tokyo Toronto This book is printed on acid-free paper. (~ Copyright © 1997 by ACADEMIC PRESS All Rights Reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Academic Press a division of Harcourt Brace & Company 525 B Street, Suite 1900, San Diego, California 92101-4495, USA http://www.apnet.com Academic Press Limited 24-28 Oval Road, London NW 1 7DX, UK http://www.hbuk.co.uk/ap/ Library of Congress Cataloging-in-Publication Data Diuretic agents : clinical physiology and pharmacology / edited by Donald Seldin, Gerhard Giebisch. p. cm. Includes index. ISBN 0-12-635690-4 (alk. paper) 1. Diuretics. I. Seldin, Donald W., date. II. Giebisch, Gerhard H. [DNLM: 1. Diuretics--pharmacology. 2. Diuretics--therapeutic use. QV 160 D6162 1997] RM377.D535 1997 615'.761--dc21 DNLM/DLC for Library of Congress 97-25926 CIP PRINTED IN THE UNrFED STATES OF AMERICA 97 98 99 00 01 02 MM 9 8 7 6 5 4 3 2 1 CONTENTS Contributors ix Preface xiii I PART A History of Diuretics I A History of Diuretics Garabed Eknoyan PART II Renal Electrolyte Transport and Its Regulation II Renal Electrolyte Transport and Its Regulation 31 Robert J. Alpern, Gerhard Giebisch, and Donald W. Seldin PART III Physiology of Diuretic Action IIIA Site and Mechanism of Action of Diuretics 75 Peter A. Friedman and Steven C. Hebert vi Contents IIIB Special Diuretics 113 Mark L. Zeidel IIIC Renal Hemodynamic Effects of Diuretics 135 L. Gabriel Navar IIID Extrarenal Effects of Diuretics 171 Biff F. Palmer PART IV Diuretic Use IVA Diuretic Pharmacokinetics and Pharmacodynamics 189 D. Craig Brater IVB1 Adaptation to Diuretic Drugs 209 David H. Ellison IVB2 Use of Diuretics in Chronic Renal Disease 233 and Nephrotic Syndrome Ami R. Patel and Kent A. Kirchner IVB3 Effect of Prostaglandin Inhibition 247 on the Action of Diuretic Agents Kent A. Kirchner IVB4 Impairment of Diuretic Secretion 259 Kent A. Kirchner IVB5 Albumin as an Adjunct to Diuretics 271 for the Treatment of Edema Mahmoud M. Salem and Kent A. Kirchner IVC 1 Intensive Diuretic Therapy: High Doses, 281 Combinations, and Constant Infusions David H. Ellison IVC2 Circulatory Support: Dopamine and Dopamine 301 Agonists as Adjuncts to Diuretic Therapy David H. Ellison IVC3 Interactions between ACE Inhibitors and Diuretics 321 John G. F. Cleland Contents vii IVC4 Atrial Natriuretic Peptide 335 Allan D. Struthers PART V Indications VA1 The Pathophysiology of Edema Formation 345 Michael Emmett and Donald W. Seldin VA2 Use of Diuretics for the Treatment of Heart Failure 359 Michael Emmett and Donald W. Seldin VA3 Diuretic Treatment of the Nephrotic Syndrome 389 Michael Emmett and Donald W. Seldin VA4 The Use of Diuretics in the Treatment of Ascites and 407 Edema in Hepatic Cirrhosis Michael Emmett and Donald W. Seldin VA5 Diuretics in Pregnancy 425 John R. Silkensen and Thomas F. Ferris VA6 Idiopathic Edema 431 John R. Silkensen and Thomas R. Ferris VB Hypertension and Its Treatment: The Place of Diuretics 437 Robert Unwin and Giovambattista Capasso VC1 Water and Electrolyte Derangements: Overhydration 461 Robert A. Star VC2 High Altitude Sickness 471 Connie C. W. Hsia VC3 Diuretics in the Treatment of Metabolic Alkaloids 483 Biff F. Palmer and Donald W. Seldin VC4 Use of Diuretics in Disorders of Calcium Metabolism 495 Neil A. Breslau VD Indications for the Use of Diuretics in Patients 513 with Renal Impairment Wadi N. Suki viii Contents VE Toxic Agents: Drug Overdose, Poisons, Contrast Media 531 Andrew Z. Fenves VF Diuretics and Glaucoma 543 John C. Schwartz VG Diuretics and Cerebral Edema 549 John C. Schwartz PART VI Diuretic Complications VIA Sodium: Volume Depletion and Hyponatremia 559 Angel Rivera-Santos and Robert A. Star VIB Potassium Disturbances Associated 571 with the Use of Diuretics Biff F. Palmer VIC Acid-Base Disturbances Associated 585 with the Use of Diuretics Biff F. Palmer VID The Effects of Diuretics on Calcium Metabolism: 595 Physiologic and Clinical Effects Khashayar Sakhaee VIE The Effects of Diuretics on Magnesium Metabolism: 611 Physiologic and Clinical Effects Khashayar Sakhaee VIF Metabolic Derangements Associated with Diuretic Use: 621 Insulin Resistance, Dyslipidemia, Hyperuricemia, and Androgenic Effects Robert T. Toto VIG Ototoxicity 637 Robert A. Star VIH Allergic Interstitial Nephritis Due to Diuretic Agents 643 Robert D. Toto Index 649 CONTRIBUTORS ROBERT J. ALPERN (31), Nephrology Division, Department of Medicine, Uni- versity of Texas Southwestern Medical Center, Dallas, Texas 75235 D. CRAIG BRATER (189), Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202-5124 NEIL A. BRESLAU (495), Center for Mineral Metabolism and Clinical Re- search and Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75235-8891 GIOVAMBATTISTA CAPASSO (437), Second University of Naples, 80100 Na- ples, Italy JOHN G. F. CLELAND (321), Medical Research Council Clinical Research Ini- tiative in Heart Failure, University of Glasgow, Glasgow G12 8QQ, United Kingdom GARABED EKNOYAN (3), Department of Medicine and Nephrology, Baylor College of Medicine, Houston, Texas 77030 DAVID H. ELLISON (209, 281,301), Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut 06520; and West Haven Center for the Study and Treatment of Kidney Disease, VA Medical Center, West Ha- ven, Connecticut 06516 MICHAEL EMMETT (345,359, 389,407), Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas 75246 ANDREW Z. FENVES (531), Nephrology/Metabolism Division, Baylor Uni- versity Medical Center, Dallas, Texas 75246 THOMAS F. FERRIS (425, 431), University of Minnesota, Minneapolis, Min- nesota 55455 ix
Description:The list of books you might like
