Disease Recurrence After Liver Transplantation: Natural History, Treatment and Survival

273 Pages·2016·5.208 MB·English

by  Paul J. Thuluvath (eds.)

Disease Recurrence
After Liver
Transplantation
Natural History,
Treatment and Survival
Paul J. Thuluvath
Editor
123
Disease Recurrence After Liver Transplantation

Paul J. Thuluvath
Editor
Disease Recurrence
After Liver Transplantation
Natural History, Treatment and Survival
Editor
Paul J. Thuluvath
Institute for Digestive Health & Liver Disease
Mercy Medical Center & University of Maryland School of Medicine
Baltimore , MD , USA
ISBN 978-1-4939-2946-7 ISBN 978-1-4939-2947-4 (eBook)
DOI 10.1007/978-1-4939-2947-4
Library of Congress Control Number: 2015947276
Springer New York Heidelberg Dordrecht London
© Springer Science+Business Media New York 2016
T his work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of
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Contents
1 Overview: Disease Recurrence After Liver Transplantation ............. 1
Paul J. Thuluvath
2 Hepatitis B Recurrence: Major Milestones and Current Status ....... 13
Bruno Roche and Didier Samuel
3 HCV Recurrence: Predictors and Outcomes
After Liver Transplantation .................................................................. 35
Angel Rubín and Marina Berenguer
4 Treatment of Recurrent Hepatitis C .................................................... 55
Anantha K. Nuthalapati and Paul J. Thuluvath
5 Recurrence of Primary Biliary Cirrhosis Following
Liver Transplantation ............................................................................ 79
Russell H. Wiesner
6 Recurrence of Autoimmune Hepatitis
After Liver Transplantation .................................................................. 91
James Neuberger
7 Alcoholic Cirrhosis, Transplantation,
and Recurrence of Disease .................................................................... 105
Eric Siskind and Rolf N. Barth
8 Recurrence of Primary Sclerosing Cholangitis
After Liver Transplantation .................................................................. 121
Phunchai Charatcharoenwitthaya and Keith D. Lindor
9 Recurrence of Metabolic Disorders
After Liver Transplantation .................................................................. 135
Bijan Eghtesad and Charles Miller
10 Nonalcoholic Fatty Liver Disease Post-Liver Transplantation .......... 145
Ibrahim Hanouneh and Bijan Eghtesad
v
vi Contents
11 Recurrence of Hepatocellular Carcinoma Following Liver
Transplantation Within Milan Criteria ............................................... 153
Anantha K. Nuthalapati , Steven I. Hanish , and Paul J. Thuluvath
12 Recurrence of HCC When Transplanted
Outside Milan Criteria .......................................................................... 165
Naveen Ganjoo and Thomas D. Schiano
13 Role of Neoadjuvant and Adjuvant Treatment
in HCC Recurrence After Liver Transplantation ............................... 187
Masato Fujiki , Federico Aucejo , Minsig Choi , and Richard Kim
14 Cholangiocarcinoma .............................................................................. 205
Nicholas Onaco and Göran B. G. Klintmalm
15 Recurrent Non-hepatic and De Novo Malignancies
After Liver Transplantation .................................................................. 215
Ashokkumar Jain , Zakiyah Kadry , Stephanie L. Buchman ,
and Ali Riaz Shah
16 Recurrence of Disease After Liver Transplantation
in the Pediatric Population .................................................................... 233
Elaine Y. Cheng , Robert S. Venick , and Ronald W. Busuttil
17 Disease Recurrence After Liver Transplantation:
Quality of Life and Cost of Retransplantation .................................... 245
Vignan Manne and Sammy Saab
Index ................................................................................................................ 259
Contributors
Federico Aucejo Transplant Center, Cleveland Clinic , Cleveland , OH , USA
Rolf N. Barth D ivision of Transplantation, U niversity of Maryland School of
Medicine , Baltimore , MD , USA
Marina Berenguer Hepatology Unit and Ciberehd, La Fe Hospital , Valencia ,
Spain
University of Medicine , Valencia , Spain
Hospital Universitari i Politècnic La Fe (Torre F-5), Valencia, Spain
Stephanie L. Buchman Division of Transplantation , Department of Surgery ,
College of Medicine, The Pennsylvania State University , Hershey, PA , USA
Ronald W. Busuttil Department of Surgery , University of California, Los Angeles ,
Los Angeles , CA , USA
Phunchai Charatcharoenwitthaya Faculty of Medicine, Division of
Gastroenterology, Medicine Department, Siriraj Hospital, Mahidol University,
Bangkok , Thailand
Elaine Y. Cheng Division of Liver and Pancreas Transplantation, Department of
Surgery , University of California, Los Angeles , Los Angeles , CA , USA
Minsig Choi Division of Hematology and Oncology , Department of Medicine,
Stony Brook University , Stony Brook , NY , USA
Didier Samuel AP-HP Hôpital Paul-Brousse, Centre Hépato-Biliaire , Villejuif ,
France
INSERM, U 1193, Villejuif, France
Univ Paris-Sud, UMR-S 1193, Villejuif, France
vii
viii Contributors
Bijan Eghtesad Department of Hepato-Pancreato-Biliary/Liver Transplantation
Surgery , Cleveland Clinic , Cleveland , OH , USA
Transplant Center, Cleveland Clinic , Cleveland , OH , USA
Masato Fujiki Transplant Center, Cleveland Clinic , Cleveland , OH , USA
Naveen Ganjoo Division of Liver Diseases , Mount Sinai Medical Center ,
New York , NY , USA
Department of Hepatology and Multi organ Transplant Aster Medcity, Kochi, India
Steven I. Hanish Department of Surgery, University of Maryland School of
Medicine, Baltimore, MD, USA
Ibrahim Hanouneh Department of Gastroenterology and Hepatology , Cleveland
Clinic , Cleveland , OH , USA
Transplant Center, Cleveland Clinic , Cleveland , OH , USA
Ashokkumar Jain D ivision of Transplantation, Department of Surgery, College of
Medicine , The Pennsylvania State University , Hershey , PA , USA
Zakiyah Kadry D ivision of Transplantation, Department of Surgery, College of
Medicine , The Pennsylvania State University , Hershey , PA , USA
Richard Kim D epartment of Gastrointestinal Oncology, H . Lee Moffi tt Cancer
Center & Research Institute , Tampa , FL , USA
Göran B. G. Klintmalm Transplant Services, Baylor University Medical Center ,
Dallas , TX , USA
Keith D. Lindor College of Health Solutions, Arizona State University , Phoenix ,
AZ , USA
Vignan Manne Department of Internal Medicine , Akron General Medical Center ,
Akron , OH , USA
Charles Miller Department of Hepato-Pancreato-Biliary/Liver Transplantation
Surgery , Cleveland Clinic , Cleveland , OH , USA
Transplant Center, Cleveland Clinic , Cleveland , OH , USA
James Neuberger Liver Unit , University Hospital Birmingham NHS Foundation
Trust , Birmingham , UK
Anantha K. Nuthalapati Institute for Digestive Health and Liver Disease, Mercy
Hospital; Department of Medicine & Surgery, University of Maryland School of
Medicine, Baltimore, MD, USA
Nicholas Onaco Transplant Services, Baylor University Medical Center , Dallas ,
TX , USA
Contributors ix
Bruno Roche AP-HP Hôpital Paul-Brousse, Centre Hépato-Biliaire , Villejuif ,
France
INSERM, U 1193, Villejuif, France
Univ Paris-Sud, UMR-S 1193, Villejuif, France
Angel Rubín Hepatology Unit and Ciberehd , La Fe Hospital , Valencia , Spain
Sammy Saab Pfl eger Liver Institute, UCLA Medical Center, U niversity of
California Los Angeles School of Medicine , Los Angeles , CA , USA
Thomas D. Schiano Division of Liver Diseases , Mount Sinai Medical Center ,
New York , NY , USA
Ali Riaz Shah Division of Transplantation, Department of Surgery, College of
Medicine , The Pennsylvania State University , Hershey , PA , USA
Eric Siskind D ivision of Transplantation, U niversity of Maryland School of
Medicine , Baltimore , MD , USA
Paul J. Thuluvath Institute for Digestive Health & Liver Disease, Mercy Medical
Center & University of Maryland School of Medicine , Baltimore , MD , USA
Robert S. Venick Division of Liver and Pancreas Transplantation, Department of
Surgery, University of California, Los Angeles, Los Angeles, CA, USA
Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics,
University of California, Los Angeles, Los Angeles, CA, USA
Russell H. Wiesner Departments of Gastroenterology/Hepatology/Liver
Transplantation , Mayo Clinic, Rochester , MN , USA