Table Of Content

~DIGESTIVE DISEASES — AND SCIENCES Formerly Published as The American Journal of Digestive Diseases New Series Volume 39, Number 1 ISSN 0163-2116 6lst Year of Continuous Publication JA N UARY 1994 DDSCDJ 39(1) 1-224 (1994) Review Article Pruritis Associated with Cholestasis: A Review of Pathogenesis and Management. M. Khandelwal and P.F. Malet Original Articles Different Response to Ursodeoxycholic Acid (UDCA) in Primary Biliary Cirrhosis According to Severity of Disease. A. Floreani, F. Zappala, M. Mazzetto, R. Naccarato, M. Plebani, and M. Chiaramonte Decreased Incidence of Viral Infections in Liver Transplant Recipients: Possible Effects of FK506? N. Singh, L. Mieles, V.L. Yu, and T.E. Starzl Clinical Course of Acute Hepatitis C and Changes in HCV Markers. K. Hino, S. Sainokami, K. Shimoda, H. Niwa, and S. lino Prospective Assessment of Incidence of Fulminant Hepatitis in Post-transfusion Hepatitis: A Study of 504 Cases. S. Takano, M. Omata, M. Ohto, and Y. Satomura Phosphorus-31 Nuclear Magnetic Resonance in Vivo Spectroscopy of Human Liver During Hepatitis A Virus Infection. Y. Yamane, M. Umeda, T. O’uchi, T. Mitsushima, K. Nakata, and S. Nagataki Pathogenesis of Varices in Schistosomal Portal Hypertension. V. Aboul-Enein, S. Arafa, and M. Sakr Effect of Isolated Portal Hypertension on Kupffer Cell Function. M.H. Basista, R.E. Stauber, D.H. Van Thiel, W.N. Tauxe, and V.J. Dindzans Daytime Ingestion of Alcohol Alters Nighttime Jejunal Motility in Man. F. Charles, D.F. Evans, F.D. Castillo, and D.L. Wingate Trophic Effects of Neurotensin in Massive Bowel Resection in the Rat. E. de Miguel, 1.A. Gdmez de Segura, H. Bonet, J.A. Rodriguez Montes, and A. Mata Plasma Enteroglucagon Levels in Different Models of Intestinal Resection in the Rat. 1.A. Gomez de Segura, E. de Miguel, A. Mata, R. Codoceo, H. Bonet, and J.A. Rodriguez Montes Impaired Interdigestive Pancreatic Polypeptide Release: Early Hormonal Disorder in Chronic Pancreatitis? O. Pieramico, D.K. Nelson, B. Glasbrenner, and P. Mailfertheiner Meal-Stimulated Canine Jejuna! Ionic Absorption: Influence of Mucosal Neural Blockade. G.J. Anthone, J.A. Bastidas, M.J. Zinner, D.C. Barnhart, F.A. Masoudi, and C.J. Yeo Expression of HLA-DR Antigens on Colonic Epithelium Around Lymph Follicles: An Anomalous Expression in Crohn’s Disease. M. Chiba, M. lizuka, Y. Horie, N. Ishii, and O. Masamune Effects of Ranitidine 150 mg Four Times a Day on 24-Hour Intragastric Acidity and 24-Hour Plasma Gastrin Concentration. A.G. Fraser, A.M. Sawyerr, M. Hudson, M. Smith, and R.E. Pounder Omeprazole Ameliorates Aspirin-Induced Gastroduodenal Injury. J.M. Scheiman, E.M. Behler, K.M. Loeffler, and G.H. Elta Increased Abdominal Pain During Final Examinations. A. Harris and B.J. Martin Inter- and Intrasubject Variability of Solid and Liquid Gastric Emptying Parameters: A Scintigraphic Study in Healthy Subjects and Diabetic Patients. S. Lartigue, Y. Bizais, S.B. Des Varannes, A. Murat, B. Pouliquen, and J.P. Galmiche Autofluorescence in Onset of Gastric Mucosal Injury Induced by Hemorrhagic Shock in Rats. H. Matsui, S. Yamagata Jr., K.-I. Hirano, M. Ishikawa, H. Fukutomi, and T. Osuga Erythromycin Accelerates Solid Emptying at the Expense of Gastric Sieving. H.C. Lin, S.L. Sanders, Y.-G. Gu, and J.E. Doty Effects of Oral Erythromycin on Esophageal pH and Pressure Profiles in Patients with Gastroesophageal Reflux Disease. G. Champion, J.E. Richter, S. Singh, C. Schan, and H. Nellans Neutrophil-Mediated Injury to Gastric Mucosal Surface Cells. R. Kozol, A. Kopatsis, S.E.G. Fligiel, R. Czanko, and D. Callewaert Superoxide Inhibition Following Different Stimuli of Respiratory Burst and Metabolism of Aminosalicylates in Neutrophils. H. Allgayer, S. Rang, U. Klotz, P. Bohne, J. Retey, W. Kruis, and R. Gugler Interleukin-1 Receptor Antagonist Does Not Prevent Endotoxin-Induced Inhibition of Gastric Acid Secretion in Rats. E. Saperas and Y. Taché Translocation of Bacteria due to Direct Mucosal Damage Caused by Gastrografin: An Experimental Study in Newborn Rats. Z. Feigenberg, H. Levavi, D. Ben-Baruch, and A. Abramovici Variability in Individual Response to Various Doses of Omeprazole: Implications for Antiulcer Therapy. V. Savarino, G.S. Mela, P. Zentilin, P. Cutela, M.R. Mele, S. Vigneri, and G. Celle Effect of Proton Pump Inhibitor, Omeprazole, on Expression of Rat Parietal Cell Specific Carbohydrate Antigen, Type 2 Chain N-Acetyllactosamine. R. Usumoto, Y. Okada, and T. Tsuji Effect of Transforming Growth Factor-a on Gastric Acid Secretion in Rats and Monkeys. A. Guglietta, C.A. Lesch, M. Romano, R.W. McClure, and R.J. Coffey Hospital Discharges Resulting from Esophagitis Among Medicare Beneficiaries. A.S onnenberg, B.T. Massey, and S.J. Jacobsen Effect of Viscosity on Oropharyngeal and Esophageal Emptying in Man. C.H. Kim, J.J. Hsu, M.K. O’Connor, A.L. Weaver, M.L. Brown, and A.A. Zinsmeister Effect of Graded Exercise on Esophageal Motility and Gastroesophageal Reflux in Nontrained Subjects. E.E. Soffer, J. Wilson, G. Duethman, J. Launspach, and T.E. Adrian Correlation of 24-Hr Esophageal pH Patterns with Clinical Features and Endoscopy in Gastroesophageal Reflux Disease. V.A. Saraswat, R.K. Dhiman, A. Mishra, and S.R. Naik Case Reports Peritoneal Kaposi’s Sarcoma: A Cause of Ascites in Acquired Immunodeficiency Syndrome. R. Leal, M. Lewin, I. Ahmad, and J. Korula Simple Hepatic Cysts: First Case Report of Percutaneous Drainage and Sclerosis with Doxycycline, with a Review of Literature. K. Tokunaga, S.K. Teplick, and B. Banerjee Listeria monocytogenes Peritonitis in Cirrhotic Patients: Value of Ascitic Fluid Gram Stain and a Review of Literature. M.H. Nguyen and V.L. Yu Letters to the Editor Deceptive Epistaxis During Gastroscopy. G. Delpre, A. Neeman, A. Leiser, and U. Kadish High Interleukin-6 Concentrations in Hepatic Ascites. T. Andus, V. Gross, A. Holstege, and J. Schélmerich Genotype of Hepatitis C Virus in Fulminant Hepatitis C.M . Yoshiba, K. Sekiyama, K. Inoue, F. Sugata, and H. Okamoto News and Notices Erratum DIGESTIVE DISEASES | AND SCIENCES Formerly Published as The American Journal of Digestive Diseases New Series Volume 39, Number 2 ISSN 0163-2116 6lst Year of Continuous Publication FEBRUARY 1994 DDSCDJ 39(2) 225-448 (1994) Original Articles 225 Quantitative Detection of Hepatitis C Virus Genome in Liver Tissue and Circulation by Competitive Reverse Transcription—Polymerase Chain Reaction. H. Nakagawa, H. Shimomura, T. Hasui, H. Tsuji, and T. Tsuji 234 Hepatitis C Virus Genotypes Are Not Responsible for Development of Serious Liver Disease. M. Yamada, S. Kakumu, K. Yoshioka, Y. Higashi, K. Tanaka, T. Ishikawa, and M. Takayanagi 240 Prognostic Value of Hepatic Volumetry in Fulminant Hepatic Failure. K. Sekiyama, M. Yoshiba, K. Inoue, and F. Sugata 245 Proliferating Cell Nuclear Antigen (PCNA) Expression in Regenerating Rat Liver After Partial Hepatectomy. S.E. Theocharis, A.S. Skopelitou, A.P. Margeli, K.J. Paviaki, and C. Kittas 253 Sphincter of Oddi Dysfunction Following Liver Transplantation: Screening by Bedside Manometry and Definitive Manometric Evaluation. V. Douzdjian, M.M. Abecassis, and F.C. Johlin 257 Sphincter of Oddi Motility in Patients with Bile Duct Stones: A Comparative Study Using Percutaneous Transhepatic Manometry. N. Yuasa, Y. Nimura, A. Yasui, Y. Akita, and K. Odani 268 Effect of Intravenous Glucose on Intravenous Amino Acid-Induced Gallbladder Contraction and CCK Secretion. S.Y. de Boer, A.A.M. Masclee, W.F. Lam, J.B.M.J. Jansen, and C.B.H.W. Lamers 275 Release of Bile Canalicular Membrane Antigen into Blood in Experimental Extrahepatic Cholestasis of the Rat. Y. Kobayashi, H. Ohta, T. Kawasaki, M. Matsumoto, K. Tamakoshi, and K. Kanai 284 Effect of Octreotide on Dynamic Excretion of Bile in Chinese Acromegalic Patients Assessed by [°°™Tc] EHIDA Hepatobiliary Scan. X.-F. Zhu, A.G. Harris, M.F. Yang, Y.-F. Shi, G. Zhou, J.-Y. Xu, and J.-X. Zhang 289 Gallbladder Ejection Fraction and Its Relationship to Sphincter of Oddi Dysfunction. T.A. Ruffolo, S. Sherman, G.A. Lehman, and R.H. Hawes 293 Peptidergic Innervation of Human Sphincter of Oddi. J. Sand, H. Tainio, and I. Nordback Peeee 301 Pepsin Concentration in Gastroduodenal Biopsy Homogenates in Chronic Ulcer Disease. F. Vianello, F. Di Mario, M. Plebani, B. Germana, P. Dal Santo, G. Leandro, P. Dotto, S.A. Grassi, G. Battaglia, and R. Naccarato 309 Helicobacter pylori Infection and Food-Cobalamin Malabsorption. R. Carmel, G.I. Perez-Perez, and M.J. Blaser 315 Prospective Evaluation of Gastric Acid Secretion and Cobalamin Absorption Following Gastric Bypass for Clinically Severe Obesity. K.E. Behrns, C.D. Smith, and M.G. Sarr 321 Reciprocal Changes in Antrai Gastrin and Somatostatin mRNA in Pernicious Anemia. S.F. Moss, S. Legon, and J. Calam eSeweewaeee ee e 327 Gastric Mucosal Toxicity of Duodenal Juice Constituents in the Rat: Acute Studies Using Ex Vivo Rat Gastric Chamber Model. D. Armstrong, E.R.C. Rytina, G.M. Murphy, and R.H. Dowling 340 Mortality Among Patients with Partial Gastrectomy for Benign Ulcer Disease. G. Lundegardh, C. Helmick, M. Zack, and H.-O. Adami 347 Intragastric Nicotine Protects Against 40% Ethanol-Induced Gastric Injury Despite Pretreatment with N©-Nitro-L-Arginine Methyl Ester or Adrenal Medullectomy in Rats. F. Iwata, K. Endoh, and F.W. Leung 353 Effect of Vagotomy on Expression of Neuropeptides and Histamine in Rat Oxyntic Mucosa. N. Back, M. Ahonen, O. Happdla, E. Kivilaakso, and T. Kiviluoto 362 Achlorhydria Does Not Protect Against Benign Upper Gastrointestinal Ulcers During NSAID Use. M. Janssen, B.A.C. Dijkmans, J.P. Vandenbroucke, I. Biemond, nups eiepete e and C.B.H.W. Lamers 366 Protection Against Gastric ischemia—Reperfusion Injury by Nitric Oxide Generators. F.J. Andrews, C. Malcontenti-Wilson, and P.E. O’Brien 374 Efficacy of Cyclosporine in Treatment of Fistula of Crohn’s Disease. D.H. Present and S. Lichtiger 381 Motilin Agonist Erythromycin Increases Human Lower Esophageal Sphincter Pressure by Stimulation of Cholinergic Nerves. S. Chaussade, S. Michopoulos, P. Sogni, J. Guerre, and D. Couturier 385 A Prospective Study of Effects of Belsey MK IV Antireflux Surgery on Endoscopic Esophagitis, Lower Esophageal Sphincter Pressure, and 24-Hr pH Measurements: Relation to Symptom Improvement. J.M.L.M. Horbach, M.H. Cnossen, J.B.M.J. Jansen, C.B.H.W. Lamers, A.H. Zwinderman, J.L. Terpstra, and H.G. Gooszen 393 Recombinant Human Epidermal Growth Factor Prevents Sclerotherapy-Induced Esophageal Ulcer and Stricture Formations in Pigs. C.O. Juhl, L.S. Jensen, T. Steiniche, and E. Moussa 402 What Is the Optimal Time Window in Symptom Analysis of 24-Hour Esophageal Pressure and pH Data? H.G.T. Lam, R. Breumelhof, J.M.M. Roelofs, G.P. van Berge Henegouwen, and A.J.P.M. Smout 410 Basal Acid Output and Gastric Acid Hypersecretion in Gastroesophageal Reflux Disease: Correlation with Ranitidine Therapy. M.J. Collen, D.A. Johnson, and M.J. Sheridan Case Reports 418 Eosinophilic Cholecystitis, Appendiceal Inflammation, Pericarditis, and Cephalosporin-Associated Eosinophilia. R.H. Felman, D.B. Sutherland, J.L. Conklin, and F.A. Mitros 423 Barrett’s Esophagus and Other Mucosal Evidence of Reflux in Asymptomatic Subjects with Abnormal 24-Hour Esophageal pH Monitoring. R. Fass and R.E. Sampliner 426 Enterocolitis Cystica Profunda Lesions in a Patient with Unclassified Ulcerative Enterocolitis. S.H. Zidi, P. Marteau, F. Piard, B. Coffin, J.-P. Favre, and J.-C. Rambaud 433 Reversal of Megaduodenum and Duodenal Dysmotility Associated with Improvement in Nutritional Status in Primary Anorexia Nervosa. A.L. Buchman, M.E. Ament, M. Weiner, A. Kodner, and E.A. Mayer Letters to the Editor st) Prediction of Interferon Effect in Chronic Hepatitis C by Both Quantification and Genotyping of HCV-RNA. G. Yamada, M. Takahashi, R. Miyamoto, T. Tsuji, H. Yoshizawa, and H. Okamoto aa Endoscopic Follow-up for All Gastric Ulcers to Detect Malignancy? P. Bytzer 442 Acute Acaiculous Cholecystitis Due to Salmonella. P. Garrido-Benedicto, E. Gonzalez-Reimers, F. Santolaria-Fernandez, and F. Rodriguez-Moreno 443 Interleukin-16 in Chronic Hepatitis C Virus Infection. E. Ozyilkan, G. Tatar, A. Hacibektasoglu, B. Kayhan, and H. Telatar ans Cholelithiasis in Cirrhotic Patients from Turkey. A. Dobrucali, S. Hiilagii, M. Altin, and I. Ding 446 HumanG astroduodenojejunal Manometry. D.L. Wingate 447 Response a Drs. Moore and Clemmer. J.G. Moore and T.P. Clemmer 44% News and Notices § DIGESTIVE DISEASES AND SCIENCES Formerly Published as The American Journal of Digestive Diseases New Series Volume 39, Number 3 ISSN 0163-2116 6lst Year of Continuous Publication MARCH 1994 DDSCDJ 39(3) 449-672 (1994) Original Articles Evaluation of Colonic Sensory Thresholds in IBS Patients Using a Barostat: Definition of Optimal Conditions and Comparison with Healthy Subjects. M. Bradette, M. Delvaux, G. Staumont, J. Fioramonti, L. Bueno, and J. Frexinos Protein Kinase C Activity as a Potential Marker for Colorectal Neoplasia. T.J. McGarrity and L.P. Peiffer Nd:YAG Laser in Treatment of Rectal Cancer: Are There Features Predicting a Curative Result? J. Escourrou, M. Delvaux, L. Buscail, T. Nicolet, and J. Frexinos Safety and Clinical Efficacy of Flexible Sigmoidoscopy and Colonoscopy for Gastrointestinal Bleeding After Myocardial Infarction: A Six-Year Study of 18 Consecutive Lower Endoscopies at Two University Teaching Hospitals. M.S. Cappell Loss of Protein Kinase C 5 Isozyme Immu~oreactivity in Human Adenocarcinomas. P.A. Craven and F.R. DeRubertis Effect cf Human Bowel Wall Distension on Translocation of Indigenous Bacteria and Endotoxins. U. Schoeffel, D. Jaegar, K. Pelz, R. Salm, and E.H. Farthmann Study of Constancy of Hydrogen-Consuming Flora of Human Colon. A. Strocchi, C.J. Ellis, J.K. Furne, and M.D. Levitt Intestinal Expression and Cellular Immune Responses to Human Heat-Shock Protein 60 in Crohn’s Disease. M.E. Baca-Estrada, R.S. Gupta, R.H. Stead, and K. Croitoru Fecal Excretion of a,-Antitrypsin in Patients with Crohn’s Disease: A Comparison of Nephelometry and Radial Immunodiffusion. A. Lépez, J. Hinojosa, A. Miralles, J. Primo, and J.D. Bermtidez Mast Cells Are Not Essential to Inflammation in Murine Model of Colitis. K.W. Chin and K.E. Barrett Study of Colonic IgG Fc Binding Site in Cultured Epithelial Cells. K. Kobayashi and W.R. Brown A Vascular Hypersensitivity Model of Acute Multifocal Gastrointestinal Infarction. M. Hudson, C. Piasecki, A.J. Wakefield, E.A. Sankey, A.P. Dhillon, M. Osborne, R. Sim, and R.E. Pounder Mucosal Glucosamine Synthetase Activity in Inflammatory Bowel Disease. M.C. Winslet, V. Poxon, A. Allan, and M.R.B. Keighley Anti-Neutrophil Cytoplasmic Antibodies (ANCA) in Sera from Patients with Inflammatory Bowel Disease (IBD): Relation to Disease Pattern and Disease Activity. J. Broekroelofs, A.H.L. Mulder, G.F. Nelis, B.D. Westerveld, J.W. Cohen Tervaert, and C.G.M. Kallenberg Respiratory Burst of Circulating Polymorphonuclear Leukocytes and Plasma Elastase Levels in Patients with Inflammatory Bowel Disease in Remission. P. Gionchetti, M. Campieri, C. Guarnieri, A. Belluzzi, C. Brignola, E. Bertinelli, M. Ferretti, M. Miglioli, and L. Barbara Childhood Infections and the Risk of Inflammatory Bowel Disease. J.1. Wurzelmann, C.M. Lyles, and R.S. Sandler Long-Term Follow-up of Children with Chronic Idiopathic Constipation. A. Staiano, M.R. Andreotti, L. Greco, P. Basile, and S. Auricchio Gastrobiliary Motility After Liquid Fatty Meal in Progressive Systemic Scierosis: A Sonographic Study. B.W edmann, M. Wegener, R.J. Adamek, and S. El Gammal Relation Between Gastric Emptying of Albumin—Dextrose Meals and Cholecystokinin Release in Man. J.B.M.J. Jansen, M. Fried, W.P.M. Hopman, C.B.H.W. Lamers, and J.H. Meyer Pyloric Motility: Sleeve Sensor Versus Strain Gauge Transducer. M. Edelbroek, J. Schuurkes, W. de Ridder, M. Horowitz, J. Dent, and L. Akkermans Role of Gastric Mucosal Blood Flow in Gastroprotective Effect of Novel Xanthine Derivative. T. Tanaka and P.H. Guth Nitric Oxide in Gastroprotection by Sucralfate, Mild Irritant, and Nocloprost: Role of Mucosal Blood Flow. S.J. Konturek, T. Brzozowski, J. Majka, A. Szlachcic, and K. Czarnobilski Gastrointestinal Irritancy, Antiinflammatory Activity, and Prostanoid Inhibition in the Rat: Differentiation of Effects Between Nabumetone and Etodolac. R. Melarange, C. Gentry, M. Durie, C. O’Connell, and P.R. Blower Effect of Synthetic Prostaglandin E, Analog Enprostil on Omeprazole-Induced Hypergastrinemia and Hyperpepsinogenemia. J.L. Meijer, L.F.S.J. Crobach, J.B.M.J. Jansen, and C.B.H.W. Lamers Somatostatin Effectively Prevents Ethanol- and NSAID-Induced Gastric Mucosal Damage in Rats. F. Karmeli, R. Eliakim, E. Okon, and D. Rachmilewitz Induction of Gastric Lesions and Hypoglycemic Response by Food Deprivation in Strepzst ozotocin-Diabetic Rats. K. Takeuchi, K. Ueshima, T. Ohuchi, and S. Okabe Estrogens, Androgens, and EGF Receptor Expression in Gastric Carcinoma Induced by N-Methyl-N’ -Nitro-N-Nitrosoguanidine. L. Polimeno, G. Silecchia, E. Spaziani, A. Scucchi, P. Dell’Aquila, E. Ilerardi, A. Materia, A. Giangaspero, N. Basso, and A. Francavilla Effect of Experimental Cold Pain Stress on Gastroesophageal Junction. P. Zacchi, F. Mearin, and J.-R. Malagelada Macroscopic Healing of Esophagitis Does Not Improve Esophageal Motility. J.M. Howard, R.P.E. Reynolds, J.V. Frei, M.A. Flowers, T.J. McDonald, K. Tilbe, and D.C. Bondy Morphology and Pathology of Radiation-Induced Esophagitis: Double-Blind Study of Naproxen vs Placebo for Prevention of Radiation Injury. E.E. Soffer, F. Mitros, J.F. Doornbos, J. Friedland, J. Launspach, and R.W. Summers Case Reports Could Immunostimulant Drugs Be Useful in Apparently Medically Refractory Crohn’s Disease? G. Nardone and G. Budillon Percutaneous Transhepatic Microwave Coagulation Therapy for Hepatocellular Carcinoma Proliferating in the Bile Duct. T. Seki, Y. Kubota, M. Wakabayashi, K. Kunieda, S. Nakatani, T. Shiro, and K. Inoue Cholangiocarcinoma and Crohn’s Disease. P.M. Choi, F.W. Nugent, M.P. Zelig, J.L. Munson, and D.J. Schoetz, Jr. News and Notices Correction DIGESTIVE DISEASES§ AND SCIENCES Formerly Published as The American Journal of Digestive Diseases New Series Volume 39, Number 4 ISSN 0163-2116 61st Year of Continuous Publication AP RIL 1994 DDSCDJ 39(4) 673-928 (1994) Editorial Why Do Functional Gastrointestinal Disorders Come and Go? N. J. Talley Original Articles Effect of Constant Light on Rhythmic Gastric Functions in Fasting Rats. K.R. Larsen, P. Barattini, M.T. Dayton, and J.G. Moore Effect of Intraduodenally Administered Histamine on Gastric Acid Secretion in Rats and Guinea Pigs. Y. Hiramatsu and S. Okabe Bleeding Peptic Ulcer Occurring in Hospitalized Patients: Analysis of Predictive and Risk Factors and Comparison with out-of-Hospital Onset Haemorrhage. S. Loperfido, F. Monica, L. Maifreni, A. Paccagnella, R. Fama, R. Dal Pos, and C. Sartori Prognostic Factors in Upper Gastrointestinal Bleeding. B. Katschinski, R. Logan, J. Davies, G. Faulkner, J. Pearson, and M. Langman Effect of FK-506, An Immunosuppressive Agent, on Genesis of Water-Immersion Stress-Induced Gastric Lesions in Rats. E.H amajima, S. Sugiyama, H. Hoshino, H. Goto, Y. Tsukamoto, and T. Ozawa Adenosine Deaminase, 5’-Nucleotidase, Xanthine Oxidase, Superoxide Dismutase, and Catalase Activities in Gastric Juices from Patients with Gastric Cancer, Ulcer, and Atrophic Gastritis. I. Durak, N. Ormeci, O. Akyol, O. Canbolat, M. Kavutcu, and M. Bilbiil Ornithine Decarboxylase (ODC) Levels in Children with Reflux Esophagitis. Y. Elitsur, W.E. Triest, and C.-H. Lin Gastric Emptying of Solid Meais in Achalasic Patients After Successful Pneumatic Dilatation of the Cardia. L. Benini, G. Castellani, C. Sembenini, E. Bardelli, S. Caliari, C. Volino, and I. Vantini Long-Term Foliow-up of Consequences of Percutaneous Endscopic Gastrostomy (PEG) Tubes in Nursing Home Patients. M. Kaw and G. Sekas Acute Gastritis Associated with Spiral Organisms from Cats. J.P. Lavelle, S. Landas, F.A. Mitros, and J.L. Conklin Effects of Chronic Normovolemic Anemia on Gastric Microcirculation and Ethanol-Induced Gastric Damage in Rats. N. Marroni, M. Casadevall, J. Panés, C. Piera J.M. Jou, and J.M. Pique Esophageal Motility Disorders in Patients with Sjégren’s Syndrome. R. Palma, A. Freire, J. Freitas, A. Morbey, T. Costa, F. Saraiva, F. Queirés, and neOeeRp. m kee A. Carvalhinhos Effect of Body Position on Deglutition. E. Dejaeger, W. Pelemans, E. Ponette, and G. Vantrappen Correlation of Lower Esophageal Mucosal Ring and Lower Esophageal Sphincter Pressure. M.Y.M. Chen, D.J. Ott, D.L. Donati, W.C. Wu, and D.W. Gelfand Nitric Oxide Mediates Inhibitory Nerve Effects in Human Esophagus and Lower Esophageal Sphincter. H.G. Preiksaitis, L. Tremblay, and N.E. Diamant eeal T eee e Balloon or Bougie for Dilatation of Benign Esophageal Stricture. J.G.C. Cox, R.K. Winter, S.C. Maslin, M. Dakkak, R. Jones, G.K. Buckton, R.C. Hoare, J.F. Dyet, and J.R. Bennett Vascular Compression of the Esophagus: A Manometric and Radiologic Study. J.G. Stagias, D. Ciarolla, S. Campo, M.I. Burrell, and M. Traube Preventive Effect of Immunosuppressive Agents Against Indomethacin-Induced Small Intestinal Ulcers in Rats. T. Matsumoto, M. lida, S. Nakamura, K. Hizawa, F. Kuroki, and M. Fujishima Mechanisms and Sites of Mannitol Permeability of Small and Large Intestine in the Rat. P. Krugliak, D. Hollander, C. Schlaepfer, H. Nguyen, and T.Y. Ma - a Bile Salts Determine Leukotriene B, Synthesis in a Human Intestinal Cell Line (CaCo-2). V.C. Dias, E.A. Shaffer, J.L. Wallace, and H.G. Parsons Long-Term Observations on Morphological Changes of Choledochal Epithelium After Choledochoenterostomy in Rats. K. Kurumado, T. Nagai, Y. Kondo, and H. Abe “‘Nonspecific”” Erosions and Ulcers of the Colonic Mucosa. C.A. Rubio and S. Nydahl Role of Vagal Dysfunction in Motility and Transit Disorders of Jejunal Roux Limb After Roux-en-Y Gastrojejunostomy. H.C.J. Van der Mijle, J.H. Kleibeuker, A.J. Limburg, H. Beekhuis, C.B.H.W. Lamers, and R. van Schilfgaarde Effect of Resistant Starch on Colonic Fermentation, Bile Acid Metabolism, and Mucosal Proliferation. 1.P. van Munster, A. Tangerman, and F.M. Nagengast Effect of a Model of Canine Jejunoileal Orthotopic Autotransplantation on Jejunal and Ileal Transport of Water and Electrolytes. A.M. Walters, A.R. Zinsmeister, and M.G. Sarr 851 Regulation of Hepatocyte Albumin and a,-Acid Glycoprotein Secretion by Monokines, Dexamethasone, and Nitric Oxide Synthase Pathway: Significance of Activated Liver Nonparenchymal Cells. Y. Itoh, T. Okanoue, F. Enjo, S. Sakamoto, S. Takami, K. Yasui, K. Kagawa, and K. Kashima 861 Fat-Storing Cell Abnormalities Associated with Endothelial Cell Damage After Cold Ischemic Storage of Rat Liver in UW Solution. A. Ohno, S. Mochida, M. Arai, K. Hirata, and K. Fujiwara Treatment of Chronic Sporadic-Type Non-A, Non-B Hepatitis with Lymphoblastoid Interferon: Gamma GT Levels Predictive for Response. G. Mazzella, A. Salzetta, S. Casanova, M.C. Morelli, N. Villanova, R. Miniero, S. Sottili, V. Novelli, A. Cipolla, D. Festi, and E. Roda 871 Glutathione and ATP Levels, Subcellular Distribution of Enzymes, and Permeability of Duct System in Rabbit Pancreas Following Intravenous Administration of Alcohol and Cerulein. R.E. Liithen, C. Niederau, and J.H. Grendell Crohn’s Disease and Cystic Fibrosis. J.D. Lloyd-Still Anti-Neutrophil Cytoplasmic Antibodies (ANCA) and Inflammatory Bowel Diseases in Chinese. J.Y. Sung, F.K.L. Chan, J. Lawton, J.C.K. Leung, C.T. Liew, N.W.Y. Leung, R. Hsu, and K.-N. Lai Letters to the Editor 893 Prostaglandins Mediate Fish Oil Protection Against Ethanol-Induced Gastric Mucosal Injury in Rats. F.W. Leung 893 Interference by Lubricating Jelly in ELISA Assay for Pepsin in Gastric Juice Samples. R. Coan, A. Allen, and J. Pearson 895 Response by Dr. Roslyn. J. Roslyn News and Notices Abstracts of the Second Osaka International Symposium on Gastroenterology, Osaka, Japan, November 22-23, 1993 » DIGESTIVE DISEASES AND SCIENCES Formerly Published as The American Journal of Digestive Diseases New Series Volume 39, Number 5 ISSN 0163-2116 60th Year of Continuous Publication MAY 1994 DDSCDJ 39(5) 929-1152 (1994) Original Articles Misoprostol is Effective Treatment for Patients with Severe Chronic Constipation. E.E. Soffer, A. Metcalf, and J. Launspach Effects of Misoprostol on Delayed Ulcer Healing Induced by Aspirin. A.G. Penney, F.J. Andrews, and P.E. O’Brien Strenuous Exercise Decreases Motility and Cross-Sectional Area of Human Gastric Antrum: A Study Using Ultrasound. B.P. Brown, M.A. Ketelaar, K. Schulze-Delrieu, M.M. Abu-Yousef, and C.K. Brown Intestinal Microflora Stimulates Myoelectric Activity of Rat Small Intestine by Promoting Cyclic Initiation and Aboral Propagation of Migrating Myoelectric Complex. E. Husebye, P.M. Hellstr6m, and T. Midtvedt Attenuation of Acetaminophen Hepatitis by Prostaglandin E,: A Histopathological Study. G.L. Monto, P.J. Scheuer, R.L. Hansing, and A.K. Burroughs Hepatitis C Infection in Potential Recipients with Normal Liver Biochemistry Does Not Preclude Renal Transplantation. S. Kazi, S. Prasad, R. Pollak, T. Holzer, C. Heynen, A.J. Fabrega, D. Pitrak, and T.J. Lavden Clinical Significance of Hepatitis C Virus (HCV) Infection in Liver Transplant Recipients: Role of Serology and HCV RNA Detection. C. Lumbreras, R. Delgado, A. Fuertes, C. Loinaz, J. Iglesias, F. Colina, J.M. Aguado, C. Gimeno, I. Garcia, M. Lizasoain, E. Moreno, and A.R. Noriega Intrahepatic Mononuclear Cell Populations and MHC Antigen Expression in Patients with Chronic Hepatitis B: Effect of Interferon-a. D.H. Van Thiel, X. Zhang, N. Baddour, H.1I. Wright, L. Friedlander, and J.S. Gavaler Predicting Interferon Therapy Efficacy from Hepatitis C Virus Genotype and RNA Titer. E. Mita, N. Hayashi, H. Hagiwara, K. Ueda, Y. Kanazawa, A. Kasahara, H. Fusamoto, and T. Kamada Delayed Gastric Emptying in Patients with Liver Cirrhosis. H. Isobe, H. Sakai, M. Satoh, S. Sakamoto, and H. Nawata Comparative Effects of Adjuvant Cimetidine and Omeprazole During Pancreatic Enzyme Replacement Therapy. M.J. Bruno, E.A.J. Rauws, F.J. Hoek, and G.N.J. Tytgat Fat-Soluble Vitamin Concentration in Chronic Alcohol-Induced Pancreatitis: Relationship with Steatorrhea. F. Marotta, D. Labadarios, L. Frazer, A. Girdwood, and I.N. Marks Hydrophobic Bile Salt Inhibits Bacterial Adhesion on Biliary Stent Material. J.Y. Sung, E.A. Shaffer, K. Lam, I. Rususka, and J.W. Costerton Cholecystokinin Analog, JMV-180, Stimulates Growth of Human Pancreatic Cancer. I.R. Swift and J.P. Smith Disproportionate Ileal Digestion on Canine Food Consumption: A Possible Model for Satiety in Pancreatic Insufficiency. J.H. Meyer, J.D. Elashoff, J.E. Doty, and Y.G. Gu Pancreatic Duct Mucosa Following Bile Salt Injury in Cats: Morphology, Barrier Function to Pancreatic Exocrine Proteins and Vulnerability by Activated Pancreatic Juice. T. Arendt, M. Hansler, and G. Appelt Effect of Antioxidant Treatment in Rats with Acute Hemorrhagic Pancreatitis. M.H. Schoenberg, M. Biichler, M. Younes, R. Kirchmayr, U.B. Brickner, and H.G. Beger Neurohumoral Mechanism Involved in Augmentation of Canine Jejunal Absorption Following Oral Rehydration Solutions. J.A. Bastidas, M.J. Zinner, and C.J. Yeo Effects of Portacaval Anastomosis on Pancreatic Islets of the Rat. D. Bani, C. Cortesini, and T.B. Sacchi Tissue-Specific Alterations of Binding Sites for Peripheral-Type Benzodiazepine Receptor Ligand [*H]PK11195 in Rats Following Portacaval Anastomosis. V.I. Raghavendra, R. Audet, G. Therrien, and R.F. Butterworth Omentum and Basic Fibroblast Growth Factor in Healing of Chronic Gastric Ulcerations in Rats. S.J. Konturek, T. Brzozowski, I. Majka, W. Pawlik, and J. Stachura Double-Blind Dose-Response Multicenter Comparison of Fedotozine and Placebo in Treatment of Nonulcer Dyspepsia. B. Fraitag, M. Homerin, and P. Hecketsweiler Role of Carbonic Anhydrase in Basal and Stimulated Bicarbonate Secretion by the Guinea Pig Duodenum. R. Muallem, R. Reimer, H.S. Odes, M. Schwenk, W. Beil, and K-F. Sewing Interrelationships Between Helicobacter pylori Infection, Nonsteroidal Antiinflammatory Drugs and Gastroduodenal Disease: A Prospective Study in Healthy Volunteers. A.V. Thillainayagam, A. Tabaqchali, S.J. Warrington, and M.J.G. Farthing Dyspepsia in Healthy Blood Donors: Pattern of Symptoms and Association with Helicobacter pylori. G.H oltmann, H. Goebell, M. Holtmann, and N.J. Talley Presynaptic Muscarinic Receptors Modulate Acetylcholine Release from Rat Antral Mucosal/Submucosal Nerves. J. Ren and R.F. Harty Effect of Arginase on Splenic Killer Cell Activity in Patients with Gastric Cancer. C.-W. Wu, C.-W. Chi, C.-K. Ho, S.-L. Chien, W.-Y. Liu, F.-K. P’eng, and S.-R. Wang Giant Duodenal Ulcer: Evaluation of Basal Acid Output, Nonsteroidal Antiinflammatory Drug Use, and Ulcer Complications. M.J. Collen, M.J. Santoro, and Y.K. Chen Combined Ambulatory Esophageal Manometry and Dual Probe pH-Metry in Evaluation of Patients with Chronic Unexplained Cough. W.G. Paterson and B.W. Murat Case Reports Small Bowel Endometriosis Masquerading as Regional Enteritis. A.M inocha, M.S. Davis, and R.A. Wright Association of Crohn’s Disease and Cogan’s Syndrome. F. Froehlich, M. Fried, J.J. Gonvers, E. Saraga, J. Thorens, and A. Pecoud Hypermagi ia-Induced Paralytic Ileus. J. Golzarian, W. Scott, Jr., and W.O. Richards Role of Endoscopic Retrograde Pancreatography in Pancreatic Ascites. Y.-C. Kuo and C.-S. Wu Erratum Intragastric pH and Upper Gastrointestinal Bleeding in the ICU. R.G. Karlstadt and D.A. Hedrich Response by Drs. Moore and Clemmer. J.G. Moore and T.P. Clemmer Human Gastroduodenojejunal Manometry. D.L. Wingate Response by Dr. Camilleri. M. Camilleri News and Notices DIGESTIVE DISEASES | AND SCIENCES Formerly Published as The American Journal of Digestive Diseases | New Series Volume 39, Number 6 ISSN 0163-2116 | 61st Year of Continuous Publication J UNE 1994 DDSCDJ 39(6) 1153-1376 (1994) | ) Editorial 1153 Efficacy of Leuprolide in Treatment of the Irritable Bowel Syndrome. J.D. Wood Original Articles 1155 Effect of Leuprolide Acetate in Patients with Moderate to Severe Functional Bowel Disease: Double-Blind, Placebo-Controlled Study. J.R. Mathias, M.H. Clench, V.G. Reeves-Darby, L.M. Fox, P.H. Hsu, P.H. Roberts, L.L. Smith, and N.J. Stiglich 1163 Effect of Leuprolide Acetate in Patients with Functional Bowel Disease: Long-Term Follow-up After Double-Blind, Placebo-Controlled Study. J.R. Mathias, M.H. Clench, P.H. Roberts, and V.G. Reeves-Darby 1171 Octreotide Increases Thresholds of Colonic Visceral Perception in IBS Patients Without Modifying Muscle Tone. M. Bradette, M. Delvaux, G. Staumont, J. Fioramonti, L. Bueno, and J. Frexinos 1179 Gastrointestinal Peptide Hormones During Postoperative Ileus: Effect of Octreotide. J.J. Cullen, J.C. Eagon, and K.A. Kelly 1185 Inhibition of Calcium-Dependent Nitric Oxide Synthase Causes Ileitis and Leukocytosis in Guinea Pigs. M.J.S. Miller, U.K. Munshi, H. Sadowska-Krowicka, J.L. Kakkis, X.-J. Zhang, S. Eloby-Childress, and D.A. Clark 1193 Double-Blind Crossover Trial of Metronidazole versus Placebo in Chronic Unremitting Pouchitis. M.V. Madden, A.S. McIntyre, and R.J. Nicholls 1197 Endothelial Proliferation in Experimental Granulomatous Colitis: Autoradiography and I histochemistry Studies. N. Pooley, L. Ghosh, J. Blanchard, and P. Sharon 1210 Experimental Colitis in Rats Induces Low-Grade Endotoxinemia Without Hepatobiliary Abnormalities. H.S. Brand, M.A.W. Maas, A. Bosma, R.J. Van Ketel, P. Speelman, and R.A.F.M. Chamuleau 1216 Myoelectric Activity During Small Bowel Allograft Rejection. H. Pernthaler, A. Kreczy, R. Plattner, G. Pfurtscheller, L. Saltuari, T. Schmid, D. Ofner, G. Klima, and R. Margreiter 1222 Effects of Artificial Ileocolonic Sphincter on Motility in Intestinal Remnant Following Subtotal Small Intestinal Resection in the Dog. E.M.M. Quigley and J.S. Thompson 1230 Verotoxin Induces Hemorrhagic Lesions in Rat Small Intestine: Temporal Alteration of Vasoactive Substances. H. Tashiro, S. Miura, I. Kurose, D. Fukumura, H. Suzuki, M. Suemastsu, M. Yoshioka, M. Tsuchiya, A. Kai, and Y. Kudoh 1239 Experimental Colitis Alters Visceromotor Response to Colorectal Distension in Awake Rats. O. Morteau, T. Hachet, M. Caussette, and L. Bueno 1249 Misoprostol Protection Against Acetaminophen-Induced Hepatotoxicity in the Rat. S.P. Lim, F.J. Andrews, and P.E. O’Brien | 1257 Role of Iron and Glutathione Redox Cycle in Acetaminophen-Induced Cytotoxicity to Cultured Rat Hepatocytes. Y. Ito, Y. Suzuki, H. Ogonuki, H. Hiraishi, | M. Razandi, A. Terano, T. Harada, and K. J. Ivey 1265 Modulation of Ischemia—Reperfusion-Induced Hepatic Injury by Kupffer Cells. Y. Shiratori, H. Kirtyama, Y. Fukushi, T. Nagura, H. Takada, K. Hai, and K. Kamii | 1273 Viral and Host Factors that Contribute to Efficacy of Interferon-a,, Therapy in Patients with Chronic Hepatitis C. A.M atsumoto, E. Tanaka, T. Suzuki, H. Ogata, | and K. Kiyosawa | 1281 Variations of Hepatitis B Virus Precore/Core Gene Sequence in Acute and Fulminant Hepatitis B. T.T. Aye, T. Uchida, S.O. Becker, M. Hirashima, T. Shikata, F. Komine, M. Moriyama, Y. Arakawa, S. Mima, M. Mizokami, and J.Y.N. Lau . 1288 Postprandial Vascular Response in Patients with Cirrhosis: Short-Term Effects of Propranoiol Administration. D. Alvarez, C. Miguez, A. Podesta, R. Terg, | | A. Sanchez Malo, J.C. Bandi, S. Sanchez, and R. Mastai 1294 Biliary Motility: Changes in Detailed Characteristics Correlated to Duodenal Migrating Motor Complex and Effects of Morphine and Motilin in Dogs. K. Yokohata, H. Kimura, Y. Ogawa, G. Naritomi, and M. Tanaka 1302 Manual and Automatic Gallstone Dissolution with Methyl tert-Butyl Ether. U. Leuschner, A. Hellstern, A. Ansell, M. Gatzen, S. Giildiituna, and M. Leuschner 1309 Effect of Single Dose of Oral Erythromycin on Gastric and Gallbladder Emptying: Simultaneous Assessment by Ultrasound. V. Arienti, F. Magri, L. Boriani, G. Maconi, L. Bassein, M. Baraldini, L. Marzio, and G. Gasbarrini 1313 Increased Biliary Protein Precedes Gallstone Formation. A.J. Moser, M.Z. Abedin, and J.J. Roslyn 1321 Effects of a New Benzodiazepine Derivative Cholecystokinin Receptor Antagonist FK480 on Pancreatic Exocrine Secretion in Anesthetized Rats. I. Tachibana and M. Otsuki 1329 Defective Proliferation and Regulatory Function of CD4* T Cells Bearing Leu-8 Homing Receptor in Primary Biliary Cirrhosis: Phorbol Myristate Acetate Enhances T-Cell Function. R. Moreno-Otero, Y. Murakawa, M.E. Kanof, M.P. Civeira, E.A. Jones, and S.P. James 1337 Pancreatic Lesions and Modifications of Pancreatic Juice in Tropical Chronic Pancreatitis (Tropical Calcific Diabetes). H. Sarles, P. Augustine, R. Laugier S. Mathew, and P. Dupuy 1345 Trypsin(ogen) Content of Pancreatic Calculi in Chronic Calcified Pancreatitis in Man. T. Hayakawa, T. Kondo, T. Shibata, M. Kitagawa, Y. Nakae, and S. Hayakawa Case Reports : 1351 Acute Liver Failure Due to Lymphoma: A Diagnostic Concern when Considering Liver Transplantation. G.M. Woolf, L.M. Petrovic, S.E. Rojter, F.G. Villamil, L.. Makowka, L.G. Podesta, L.S. Sher, L. Memsic, and J.M. Vierling i 1359 Gastroiatestinal Hemorrhage and Intestinal Ischemia Associated with Anticardiolipin Antibodies. M.S. Cappell, N. Mikhail, and N. Gujral 4 1365 Duodenal Diaphragmlike Stricture Induced by Acetylsalicylic Acid. G.H. Blinder, M.L. Hautekeete, J.P. Holvoet, M.M. Kockx, and H.K.L. Hubens 1370 Toxocara canis Infection Presenting as Eosinophilic Ascites and Gastroenteritis. J.L. Van Laethem, F. Jacobs, P. Braude, A. Van Gossum, and J. Deviere 4 Book Reviews j 1373 Clinical GI Physiology for the Exam Taker. Reviewed by J. Orchard 5 1373 Surgery of the Anus, Rectum and Colon. Reviewed by C.E.H. Scott-Conner j 1375 News and Notices j DIGESTIVE DISEASES AND SCIENCES Formerly Published as The American Journal of Digestive Diseases New Series Volume 39, Number 7 ISSN 0163-2116 6lst Year of Continuous Publication JULY 1994 DDSCDJ 39(7) 1377-1600 (1994) Original Articies 1377 Dynamic Imaging of Obstructed Opossum Esophagus: From Altered Load to Altered Contractility. C. Lu, K. Schulze-Delrieu, S. Shirazi, M. Cram, and J. Raab 1389 Effect of Cimetropium Bromide on Esophageal Motility and Transit in Patients Affected by Primary Achalasia. L. Marzio, L. Grossi, M.F. DeLaurentiis, L. Cennamo, D. Lapenna, and F. Cuccurullo 1395 Open Label Study of Long-Term Effectiveness of Cisapride in Patients with Idiopathic Gastroparesis. B.M. Dworkin, W.S. Rosenthal, A.R. Casellas, R. Girolomo, E. Lebovics, S. Freeman, and S.B. Clark 1399 Effect of Erythromycin on Antroduodenal Motility in Children with Chronic Functional Gastrointestinal Symptoms. C. Di Lorenzo, A.F. Flores, T. Tomomasa, and P.E. Hyman 1405 Effect of CGRP Antagonist, alpha-CGRP 8-37, on Acid Secretion in the Dog. D.C. Lawson, C.R. Mantyh, and T.N. Pappas 1409 Gastroparesis of Digestible and Indigestible Solids in Patients with Insulin-Dependent Diabetes Mellitus or Functional Dyspepsia. A.M. Caballero-Plasencia, M.C. Muros-Navarro, J.L. Martin-Ruiz, M. Valenzuela-Barranco, M.C. de los Reyes-Garcia, R. Vilchez-Joya, F.J. Casado-Caballero, and B. Gil-Extremera 1416 New Method for Improving Accuracy of 24-Hour Continuous Intragastric pH-metry: Reflections on Physiological and Pharmacological Studies. G.S. Mela, V. Savarino, A. Malesci, F. Di Mario, P. Sossai, S. Vigneri, and A. Zambotti 1425 RUDER—A Prospective, Two-Year, Multicenter Study of Risk Factors for Duodenal Ulcer Relapse During Maintenance Therapy with Ranitidine. D. Armstrong, R. Arnold, M. Classen, M. Fischer, H. Goebell, W. Schepp, A.L. Blum, and the RUDER Study Group | 1434 Idiopathic Gastric Acid Hypersecretion: Comparison with Zollinger-Ellison Syndrome. M.J. Collen and R.T. Jensen 144i Response of Gastric Fundus to Rectal Distention in Healthy Persons. J. Zighelboim, N.J. Talley, and S.F. Phillips 1446 Histamine as an Intermediate Growth Factor in Genesis of Gastric ECLomas Associated with Hypergastrinemia in Mastomys. 1.M. Modlin, R.R. Kumar, C.J. Soroka, H. Ahiman, O. Nilsson, and J.R. Goldenring | 1454 Growth Regulation of Rabbit Gastric Epithelial Cells and Protooncogene Expression. K. Yoshiura, S. Ota, A. Terano, M. Takahashi, Y. Hata, T. Kawabe, H. Mutoh, H. Hiraishi, R. Nakata, K. Okano, and M. Omata | 1464 Uremia in the Rat Affects Gastric Cell Growth and Differentiation. E. Quintero, G. Ohning, and P.H. Guth 1469 Cimetidine Does Not Impair Pulmonary Clearance of Pseudomonas aeruginosa in Normal Rats. E. Daon, W. Summer, S. Nelson, and C. Mason AtCAl= e iNc 1473 Antisecretory Effects of Three Omeprazole Regimens for Maintenance Treatment in Duodenal Ulcer. V. Savarino, G.S. Mela, P. Zentilin, P. Cutela, M.R. Mele, D. Perilli, A. Vassallo, A. Zambotti, C. Mansi, and G. Celle 1483 Medium- and High-Dose Omeprazole Plus Amoxicillin for Eradication of Helicobacter pylori in Duodenal Ulcer Disease. J. Labenz, G.H. Riihl, J. Bertrams, and G. Boérsch 1488 Helicobacter pylori Infection in Children: Is There Specific Symptomatology? R. Reifen, I. Rasooly, B. Drumm, K. Murphy, and P. Sherman 1493 Helicobacter pylori Potentiates Histamine Release from Rat Serosal Mast Cells Induced by Bile Acids. E. Masini, P. Bechi, R. Dei, M.G. Di Bello, and T. Bani Sacchi 1501 Prevalence and Significance of Anticardiolipin Antibodies in Crohn’s Disease. P. Chamouard, L. Grunebaum, M.-L. Wiesel, J.-M. Freyssinet, B. Duclos, J.-P. Cazenave, and R. Baumann 1505 Lactulose Hydrogen Breath Test in Orocecal Transit Assessment: Critical Evaluation by Means of Scintigraphic Method. G. Sciarretta, A. Furno, M. Mazzoni, B. Garagnani, and P. Malaguti 1511 The Effect of Ileal Oleate on Interdigestive Intestinal Motility of the Dog. Z. Dreznik, T.A. Meininger, J.A. Barteau, D. Brocksmith, and N.J. Soper oa— e> e e 1519 Prevalence of Lactose Maldigestion: Influence and Interaction of Age, Race, and Sex. D.R. Rao, H. Bello, A.P. Warren, and G.E. Brown 1525 Mucosal Concentrations of Interleukin-18, Interleukin-6, Interleukin-8, and Tumor Necrosis Factor-a in Pelvic Ileal Pouches. P. Gionchetti, M. Campieri, A. Belluzzi, E. Bertinelli, M. Ferretti, C. Brignola, G. Poggioli, M. Miglioli, and L. Barbara 1532 Enteroglucagon: A Putative Humoral Factor Inducing Pancreatic Hyperplasia After Proximal Small Bowel Resection. T. Bamba, M. Sasaki, and S. Hosoda 1537 Prostanoids and Oxygen Free Radicals in Early Stages of Experimental Acute Pancreatitis. D. Closa, G. Hotter, J. Rosello-Catafau, O. Bulbena, L. Fernandez-Cruz, and E. Gelpi 1544 Direct, C tration-Depend t Inhibition by Taurocholate of Pancreatic Exocrine Secretion and CCK Release in Conscious Rats. H. Tomita, K. Miyasaka, M. Matsumoto, and A. Funakoshi 1550 Colonoscopy of Acute Colitis: A Safe and Reliable Tool for Assessment of Severity. F. Carbonnel, A. Lavergne, M. Lémann, A. Bitoun, P. Valleur, P. Hautefeuille, A. Galian, R. Modigliani, and J.-C. Rambaud 1558 Anorectal Manometric Abnormalities and Colonic Propulsive Impairment in Patients with Severe Chronic Idiopathic Constipation. G. Bassotti, G. Chiarioni, I. Vantini, C. Betti, C. Fusaro, M.A. Pelli, and A. Morelli 1565 Role of Helicobacter pylori in Cirrhotic Patients with Peptic Ulcer: A Serological Study. J.-J. Chen, C.-S. Changchien, D.-I. Tai, S.-S. Chiou, C.-M. Lee, and C.-H. Kuo 1569 Effect of Anti-allergic Agents on Chemotaxis of Neutrophils by Stimulation of a Chemotactic Factor Released from Hepatocytes Exposed to Ethanol. Y. Shiratori, H. Takada, K. Hai, H. Kiriyama, E. Mawet, Y. Komatsu, Y. Niwa, M. Matsumura, S. Shiina, T. Kawase, K. Matsumoto, K. Kamii, M. Omata, and M. Tanaka 1576 Percutaneous Treatment of Hydatid Cysts Under Sonographic Guidance. C. Bastid, C. Azar, M. Doyer, and J. Sahel 1581 Improvement of Cyclosporin A-Induced Cholestasis by Tauroursodeoxycholate in a Long-Term Study in the Rat. P.E. Queneau, P. Bertault-Peres, M. Guitaoui, E. Mesdjian, A. Durand, and J.C. Montet 1586 Biliary Lipid Composition in Heterozygous Familial Hypercholesterolemia and Influence of Treatment with Probucol. N. Tanno, S. Oikawa, M. Koizumi, H. Kotake, H. Hirakawa, Y. Kanazawa, and T. Toyota Letters to the Editor 1592 SEM Examination of Gastroesophageal Junction. K. Hoshika 1592 Helicobacter pylori Activates Gastric Mucosal Mast Cells. M. Plebani, D. Basso, F. Vianello, and F. Di Mario 1593 Association of Symptoms with Acid Reflux During Esophageal pH Monitoring. B.T. Johnston, N. McDougall, J.S.A. Collins, R.J. McFarland, and A.H.G. Love 1594 Omeprazole in Possible Esophageal Crohn’s Disease. R.T. Przemioslo and A.S. Mee 1595 Hamartoma of Brunner’s Glands with Heterotopic Pancreatic Tissue Causing Massive Haematemesis and Pyloric Obstruction. A. Kostakis, G. Kouraklis, and J. Delladetsina 1596 HCV Infection and Hepatocellular Carcinoma in Cirrhotics: What Is the Linkage? M. Coltorti, N. Caporaso, M. Persico, I. de Sio, R. Marmo, F. Morisco, C. Tuccillo, and M. Romano News and Notices DIGESTIVE DISEASES §f AND SCIENCES ~ Formerly Published as The American Journal of Digestive Diseases New Series Volume 39, Number 8 ISSN 0163-2116 6lst Year of Continuous Publication AUGUST 1994 DDSCDJ 39(8) 1601-1838 (1994) Original Articles 1601 Exclusion of Meal Periods from Ambulatory 24-Hour pH Monitoring May Improve Diagnosis of Esophageal Acid Reflux. J.M. Wo and D.M. Castell 1608 Pattern of 72-Hour Intragastric Acidity in a Homogeneous Group of Intensive Care Unit Patients. W.P. Geus, S.J. Smith, J.A.M. de Haas, and C.B.H.W. Lamers 1613 Helicobacter pylori is Associated with Alterations in Intestinal Gas Profile Among Patients with Nonulcer Dyspepsia. A. Minocha, S. Siddiqi, P.S. Rahal, and R.L. Vogel 1618 § Gastrospirillum hominis Prevalence (Letter to the Editor). J.C. Debongnie 1619 Asynchrony in Circadian Rhythms of Gastric Function in the Rat: A Modei for Gastric Mucosal Injury. J.G. Moore, K.R. Larsen, P. Barattini, and M.T. Dayton 1625 Acid Secretory and Duodenal Ulcerogenic Responses Induced by Mepirizole in Anesthetized Rats: Relation to Body Temperature. K. Ueshima, K. Takeuchi, T. Ohuchi, and S. Okabe 1633 Celiac Disease and Insulin-Dependent Diabetes Mellitus: Screening in an Adult Population. C. Sategna-Guidetti, S. Grosso, R. Pulitand, E. Benaduce, F. Dani, and Q. Carta 1638 | Low-Dose 6-Mercaptopurine in Inflammatory Bowel Disease is Associated with Minimal Hematologic Toxicity. C.N. Bernstein, L. Artinian, P.A. Anton, and F. Shanahan 1642 An Evaluation of Antimicrobial Treatment for Whipple’s Disease: Tetracycline versus Trimethoprim-Sulfamethoxazole. G.E. Feurle and T. Marth 1649 Granulomatous Gastroenteritis: Case Report with Comparison to Idiopathic Isolated Granulomatous Gastritis (Case Report). M.J. Zuckerman, M. Al-Samman, and D.A. Boman 1655 Adrenergic, Purinergic, and Endothelial Mediators and Modulators of Norepinephrine-Induced Mesenteric Autoregulatory Escape. G. Remak, O.D. Hottenstein, and E.D. Jacobson 1665 Duodenal Nutrients Inhibit Canine Jejunal Fasting Motor Patterns Through a Hormonal Mechanism. K.E. Behrns and M.G. Sarr 1672 Limonene in Expired Lung Air of Patients with Liver Disease. M.I. Friedman, G. Preti, RO. Deems, L.S. Friedman, S.J. Munoz, and W.C. Maddrey 1677 Lack of Evidence for Hepatitis B Virus (HBV) Infection in Fulminant Non-A, Non-B Hepatitis. T. Laskus, J. Rakela, R.H. Wiesner, veaeee J.L. Steers, and D.H. Persing 1683 Microvascular Changes in the Liver After Ischemia—Reperfusion Injury: Protection with Misoprostol. S.P. Lim, F.J. Andrews, C. Christophi, and P.E. O’Brien 1691 Diagnosis of Acute Hepatitis E Infection Utilizing Enzyme Immunoassay (Case Report). L.J. DeGuzman, D.L. Pitrak, G.J. Dawson, D.C. Shin, T.J. Holzer, and T.J. Layden 1694 Hepatic Abscess Caused by Salmonella typhi: A Case Report and Review of the Literature (Case Report). P.N. Soni, A.A. Hoosen, and D.G. Pillay 1697 Symptomatic versus Silent Gallstones: Radiographic Features and Eligibility for Nonsurgical Treatment. E. Ros, R. Valderrama, C. Bru, L. Bianchi, and J. Terés 1704 Natural History of Galistones in Non-Insulin-D dent Diabetes Mellitus: A Prospective 5-Year Follow-Up. G. Del Favero, A. Caroli, T. Meggiato, A. Volpi, P. Scalon, A. Puglisi, and F. Di Mario 1708 §Agenesis of Dorsal Pancreas in a Patient with Weight Loss and Diabetes Mellitus (Case Report). W.A. Klein, M.A. Dabezies, A.C. Friedman, D.F. Caroline, G.H. Boden, and S. Cohen 1714 Survey of Informed Consent for Endoscopic Retrograde Cholangicpancreatography. J. Newton, R. Hawes, P. Jamidar, J. Harig, and G. Lehman 1719 Ephysematous Cholecystitis After ERCP (A Case Report). C. Alvarez, K. Hunt, S.W. Ashley and H.A. Reber 1724 News and Notices 1725 Abstracts of the 10th International Symposium on Gastrointestinal Hormones, Santa Barbara, California, August 27-31, 1994 § DIGESTIVE DISEASES| AND SCIENCES Formerly Published as The American Journal of Digestive Diseases New Series Volume 39, Number 9 ISSN 0163-2116 6lst Year of Continuous Publication SEPTEMBER 1994 DDSCDJ 39(9) 1839-2062 (1994) ® Esophageal, Gastric, and Duodenal Disorders | 1839 REVIEW ARTICLE: Role of Dopamine and Other Stimuli of Mucosal Bicarbonate Secretion in Duodenal Protection. G. Flemstrom and B. Safsten 1843. Acid Suppression and Gastric Mucosal Cell Biology. G. Delle Fave, H. Helander, S. Holt, I.M. Modlin, R. Powers, E. Solcia, A. Soll, Y. Tielemans, and N.A. Wright 1853. Metoclopramide Inhibits Development of Esophageal Varices in Rat Model. M. Ohta, M. Hashizume, K. Tanoue, K. Ueno, K. Komori, T. Ishii, S. Kitano, and K. Sugimachi 1859 Primary Antral Gastritis in Young American Children: Low Prevalence of Helicobacter pylori Infections. J.D. Snyder, S.C. Hardy, G.M. Thorne, B.Z. Hirsch, and D.A. Antonioli 1864 Protection Against Necrotizing Agents-Induced Gastric Lesions in Rats: Unrelated to Inhibition of Gastric Motility. C.A. Gutiérrez-Cabano 1872 Nerve-Mediated Nitric Oxide Production by Opossum Lower Esophageal Sphincter. J. Murray, J.N. Bates, and J.L. Conklin 1877 CASE REPORT: Recovery of Esophageal Peristalsis After Congenital Tracheoesophageal Fistula Repair in an Adult. F. Mearin, A. Balboa, and J.-R. Malagelada 1882 LETTER: Gastroprotective Effect of Zinc: D. Lapenna and F. Cuccurullo 1883 RESPONSE: O. Bulbena @ Intestinal Disorders, Inflammatory Bowel Disease, Immunology, and Microbiology | : 1885 REVIEW ARTICLE: Immunomodulator Therapy in Inflammatory Bowel Disease. P.M. Choi and S.R. Targan | 1893 Characterization of Circulating Interleukin-1 Receptor Antagonist Expression in Children with Inflammatory Bowel Disease. J.S. Hyams, J.E. Fitzgerald, N. Wyzga, W.R. Treem, C.J. Justinich, and D.L. Kreutzer 1900 Analysis of T-Lymphocyte Subpopulations in Inflammatory Bowel Diseases by Three-Color Flow Cytometry. G.A Neil, R.W. Summers, B.A. Cheyne, C. Carpenter, W.-L. Huang, and T.J. Waldschmidt 1909 Serum Immunoglobulin G Reactive with Endothelial Cells in Inflammatory Bowel Disease. A.M. Sawyerr, B.E. Pottinger, C.O. Savage, N.J. Bradley, M. Hudson, A.J. Wakefield, J.D. Pearson, and R.E. Pounder 1918 Circulating Soluble Intercellular Adhesion Molecule-1 (sI1CAM-1) in Active Inflammatory Bowel Disease. O.H. Nielsen, E. Langholz, J. Hendel, and J. Brynskov 1924 IgA Antibodies to Jejunum: Specific Immunity Directed Against Target Organ of Gluten-Sensitive Enteropathy. U. Volta, N. Molinaro, D. Fratangelo, and F.B. Bianchi 1930 Anemia in Crohn’s Disease: Importance of Inadequate Erythropoietin Production and Iron Deficiency. C. Gasché, W. Reinisch, H. Lochs, B. Parsaei, S. Bakos, J. Wyatt, G.F. Fueger, and A. Gangl 1935 Chronic Abdominal Wall Pain: Diagnostic Validity and Costs. D.S. Greenbaum, R.B. Greenbaum, J.G. Joseph, and J.E. Natale | @ Motility, Nerve—Gut Interactions, Hormones, and Receptors 1942 Intestinal Dysmotility in Patients with Sphincter of Oddi Dysfunction: A Reason for Failed Response to Sphincterotomy. E.E. Soffer and F.C. Johlin 1947 Abnormal Gastrointestinal Motility in Patients with Celiac Sprue. G. Bassotti, G. Castellucci, C. Betti, C. Fusaro, M.L. Cavalletti, A. Bertotto, F. Spinozzi, A. Morelli, and M.A. Pelli 1955 Distention-Stimulated Propagated Contractions in the Human Colon. G. Bassotti, M. Gaburri, B.P. Imbimbo, A. Morelli, and W.E. Whitehead Contents continued inside DIGESTIVE DISEASES AND SCIENCES New Series Volume 39, Number 9 September 1994 Contents continued from front cover 1961 Characterization of Distal Colonic Motility in Early Postoperative Period and Effect of Colonic Anastomosis. J.P. Roberts, M.J. Benson, J. Rogers, J.J. Deeks, and N.S. Williams 1968 Manometric Patterns of Rat Colonic Motor Activity and Defecation: Effect of Selective SHT,, Agonist 8-OH-DPAT. T. Croci, G. Basilisco, A. Bassani, and L. Manara |@ Pancreatic and Biliary Disorders | 1974. CCK-Receptor Antagonists Proglumide and Loxiglumide Stimulate Bile Flow and Biliary Glutathione Excretion. K. Sztefko, P. Li, N. Ballatori, and W.Y. Chey 1981 Natural History and Treatment with Ursodiol of Gallstones Formed During Rapid Loss of Weight in Man. J.W. Marks, T. Stein, and L.J. Schoenfield 1985 Hepatoduodenal Bile Transit in Cholecystectomized Subjects: Relationship with Sphincter of Oddi Function and Diagnostic Value. E. Corazziari, M. Cicala, F.1. Habib, F. Scopinaro, F. Fiocca, N. Pallotta, A. Viscardi, A. Vignoni, and A. Torsoli 1994 CASE REPORT: Bronchobiliary Fistula Secondary to Biliary Lithiasis: Treatment of Endoscopic Sphincterotomy. | V.F. Moreira, C. Arocena, F. Cruz, M. Alvarez, and A.L. San Roman |@ Liver: Infectious, Inflammatory, and Metabolic Disorders | 7 2000 Nucleotide Sequence Analysis of the Precore Region in Patients with Spontaneous Reactivation of Chronic | Hepatitis B. T. Laskus, J. Rakela, M.J. Tong, and D.H. Persing | 2007 Interferon-a,, Increases Serum Concentration of Hyaluronic Acid and Type III Procollagen Aminoterminal Propeptide in Patients with Chronic Hepatitis B Virus Infection. G. Zohrens, T. Armbrust, K.-H. Meyer zum Biischenfelde, and G. Ramadori Ee—RWeE Y :a wneeenayeee r e 2014 Hepatic Expression of Interferon-a in Chronic Hepatitis B Virus Infection. J.W.S. Fang, P.C. Wu, C.L. Lai, C.K. Lo, A. Meager, and J.Y.N. Lau 2022 IgM and IgA Antibodies Generated Against Hepatitis C Virus Core Antigen in Patients with Acute and Chronic HCV Infection. S. Sato, S. Fujiyama, M. Tanaka, M. Goto, Y. Taura, S.-I. Kawano, T. Sato, and H. Yasuo 2032 CASE REPORT: Acute Hepatitis Induced by HMG-CoA Reductase Inhibitor, Lovastatin. S Grimbert, D. Pessayre, C. Degott, and J.-P. Benhamou | © Gastrointestinal Oncology 2034 Long-Term Prognosis of Well-Differentiated Adenocarcinoma in Endoscopically Removed Colorectal Adenomas. K.N. Cunningham, L.R. Mills, B.M. Schuman, and D.H. Mwakyusa 2038 Prognostic Value of Cytosolic Estrogen Receptors in Human Colorectal Carcinoma and Surrounding Mucosa: Preliminary Results. A. Di Leo, C. Messa, F. Russo, G. Misciagna, V. Guerra, R. Taveri, and S. Leo 2043 p53 Mutations in Flat- and Polypoid-Type Colorectal Tumors Detected by Temperature-Gradient Gel Electrophoresis. Y. Yamamura-Idei, K. Satonaka, T. Fujimori, S. Maeda, and T. Chiba 2049 CASE REPORT: Ectopic ACTH Syndrome Due to Colonic Neuroendocrine Tumor. I.L.P. Beales 2051 CASE REPORT: Gastrointestinal Autonomic Nerve Tumor Presenting as High-Grade Sarcoma: Case Report and Review of the Literature. J.R. Thomas, R.E. Mrak, and N. Libuit |© Diagnostic and Interventional Techniques 2056 Sulfamethizole Capsule Method: A New Method for Assessing Gastric Emptying of Solids. T. Asada, Y. Sako, M. Murakami, Y. Fukushima, Y. Yonekura, J. Konishi, T. Kita, T. Miyake, and T. Asada 2062 | @ News and Notices