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Diagnosis in Andrology PDF

255 Pages·1980·8.91 MB·English
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DIAGNOSIS IN ANDROLOGY CLINICS IN ANDROLOGY E.S.E. HAFEZ, series editor VOLUME 4 1. J.C. Emperaire, A. Audebert, E.S.E. Hafez, eds., Homologous artificial insemination, 1980. ISBN 90-247-2269-1. 2. L.I. Lipshultz, J.N. CorriereJr., E.S.E. Hafez, eds., Surgery of the male reproductive tract, 1980. ISBN 90-247-2315-9. 3. E.S.E. Hafez, ed., Descended and cryptorchid testis, 1980. ISBN 90-247-2299-3. 5. G.R. Cunningham, W.-B. Schill, E.S.E. Hafez, eds., Regulation of male fertility, 1980. ISBN 90-247-2373-9. 6. E.S.E. Hafez, E. Spring-Mills, eds., Prostatic carcinoma: biology and diagnosis, 1980. ISBN 90-247-2379-5. 7. S.J. Kogan, E.S.E. Hafez, eds., Pediatric andrology, 1981. ISBN 90-247-2407-7. Series ISBN: 90-247-2333-7. DIAGNOSIS IN ANDROLOGY edited by 1. BAIN Toronto, Ontario, Canada and E.S.E. HAFEZ Detroit, Michigan, U.S.A . • 1980 MARTINUS NIJHOFF PUBLISHERS THE HAGUE / BOSTON / LONDON Distributors: for the United States and Canada Kluwer Boston, Inc. 190 Old Derby Street Hingham, MA 02043 USA for all other countries Kluwer Academic Publishers Group Distribution Center P.O. Box 322 3300 AH Dordrecht The Netherlands Library of Congress Cataloging in Publication Data Main entry under title: Diagnosis in andrology. (Clinics in andrology; v. 4) Includes index. 1. Men - Diseases - Diagnosis. 2. Andrology. l. Bain, Jerald. II. Hafez, E.S.E., 1922- III. Series. RC875.D47 616.6'5075 80-36708 ISBN-13: 978-94-011-7513-5 e-ISBN-13: 978-94-011-7511-1 001: 10.1007/978-94-011-7511-1 Copyright © 1980 by Martinus Nijhoff Publishers bv, The Hague. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher, Martinus Nijhoff Publishers bv, P.O. Box 566, 2501 CN The Hague, The Netherlands. TABLE OF CONTENTS Contributors VII Foreword IX 1. ENDOCRINOLOGIC AND GENETIC ASPECTS 1. Diagnosis of hypothalamic-pituitary disorders in andrology 5 M.H.K. SHOKEIR, Y. LEFEBVRE 2. Genetic and chromosomal evaluation in andrology 19 M.H.K. SHOKEIR 3. Sexual ambiguity at birth 31 P. SAENGER, L.S. LEVINE, S. PANG, M.l. NEW 4. Thyroid function and male reproduction 53 K. GILBERG, P.G. WALFISH 5. Male reproductive function in diabetes mellitus 61 B.S. LEIBEL, P.R. GARNER II. REPRODUCTIVE ORGANS 6. Subfertility and infertility in the male - a persistent dilemma 79 l.S. GOTTESMAN, J. BAIN 7. Testicular biopsy; structur(ll aspects 87 M.B. BUCKSPAN, Y.c. BEDARD, TJ. COLGAN 8. Testicular biopsy: fine structure 93 E.S.E. HAFEZ 9. Inguinal hernia and hypospadias 109 J.F. REDMAN 10. Hydrocele, spermatocele and varicocele 121 S.D. GRAHAM, JR., D.F. PAULSON VI T ABLE OF CONTENTS 11. Testicular tumors and cancer of the penis 135 M.A.S. JEWETT, J.L. CHIN III. RADIOLOGICAL TECHNIQUES 12. Diagnostic radiology in andrology 153 W.A. CUMMING, J.E. CAMPBELL 13. Nuclear medicine in andrology 171 N.D. GREYSON 14. Ultrasonic techniques in andrology 185 M. MISKIN IV. SYSTEMIC DISORDERS 15. Neurological disorders in andrology 195 P.O. LUNDBERG 16. Andrological disorders in nephrology 215 G. BUCCIANTE, A. BERNARDI 17. Andrological problems in gastrointestinal disorders 225 L.J. COLE, R. BACCHUS 18. Andrological disorders in hematology 241 H. GOLDENBERG, L.M.C. GOLDENBERG Subject Index 255 CONTRIBUTORS BACCHUS, R.: 222 Elm Street, # 1408, Toronto, M5T IK5, GRAHAM, JR, S.D.: P.O. Box 2977, Duke University Medical Ontario, Canada Center, Durham, NC 27710, U.S.A. BAIN, J.: Mount Sinai Hospital, 600 University Avenue, GREYSON, N.D.: Division of Nuclear Medicine, Mount Sinai Toronto, M5G IX5, Ontario, Canada Hospital, 600 University Avenue, Toronto, M5G IX5, BEDARD, Y.c.: Mount Sinai Hospital, 600 University Avenue, Ontario, Canada Toronto, M5G IX5, Ontario, Canada HAFEZ, E.S.E.: Department of Gynecology-Obstetrics, School BERNARDI, A.: Istituti Di Medicina Clinica dell'Universita di of Medicine, Wayne State University, Detroit, MI, 48201, Padova, 35100 Padova, Via Giustiniani, 2 Padova, Italy U.S.A. BUCCIANTE, G.: Istituti Di Medicina Clinica dell'Universita di JEWETT, M.A.S.: Division of Urology, Wellesley Hospital, 160 Padova, 35100 Padova, Via Giustiniani, 2, Padova, Italy Wellesley Street East, Toronto, M4Y 113, Ontario, Canada BUCKSPAN, M.B.: Mount Sinai Hospital, 600 University Avenue, LEFEBVRE, Y.: Departments of Medicine and Medical Bio Toronto, M5G IX5, Ontario, Canada chemistry, University of Calgary, Calgary, Alberta, Canada CAMPBELL, J.E.: Department of Radiology, Sunnybrook Medi LEIBEL, B.S.: Hospital for Sick Children, 555 University Avenue, cal Centre, 2075 Bayview Avenue, Toronto, M4N 3M5, Toronto, M5G IX8, Ontario, Canada Ontario, Canada LEVINE, L.S.: The New York Hospital-Cornell Medical Center, 525 East 68th Street, New York, NY 10021, U.S.A. CHIN, J.L.: Department of Surgery, Wellesley Hospital, 160 LUNDBERG, P.O.: Akademiska Sjukhuset, Neurologiska klini Wellesley Street East, Toronto, M4Y 113, Ontario, Canada ken, 750 14 Uppsala 14, Sweden COLE, L.J.: 99 Avenue Road, Toronto, M5R 2G5, Ontario, MISKIN, M.: Division of Diagnostic Ultrasound, Mount Sinai Canada Hospital, 600 University Avenue, Toronto, M5G IX5, COLGAN, T.1.: 386 Glengarry Avenue, Toronto, M5M IE8, Ontario, Canada Ontario. Canada NEW, M.I.: The New York Hospital-Cornell Medical Center, CUMMING, W.A.: Department of Radiology, Oakville Trafalgar 525 East 68th Street, New York, NY 10021, U.S.A. Memorial Hospital, 327 Reynolds Street, Oakville, L6J 3L7, PANG, S.: The New York Hospital-Cornell Medical Center, 525 Canada East 68th Street, New York, NY 10021, U.S.A. GARNER, P.R.: Department of Obstetrics and Gynecology, PAULSON, D.F.: Division of Urology, Duke University Medical Ottawa Civic Hospital, 1053 Carling Avenue, Ottawa, KIY Center, P.O. Box 2977, Durham, NC 27710, U.S.A. 4E9, Ontario, Canada REDMAN, J.F.: Department of Urology, University of Arkansas GILBERG, K.: Organon Canada Limited, 565 Coronation Drive, for Medical Sciences, 4301 W. Markham, Little Rock, AK West Hill, MIE 4S2, Ontario, Canada 72201, U.S.A. GOLDENBERG, H.: 99 Avenue Road, Toronto, M5R 2G5, SAENGER, P.: The New York Hospital-Cornell Medical Center, Ontario, Canada 525 East 68th Street, New York, NY 10021, U.S.A. GOLDENBERG, L.M.C.: 99 Avenue Road, Toronto, M5R 2G5, SHOKEIR, M.H.K.: Room 515, Ellis Hall, University Hospital, Ontario, Canada Saskatoon, S7N OWO, Saskatchewan, Canada GOTTESMAN, I.S.: 15 Coach Liteway, Willowdale, M2R 3J8, WALFISH, P.G.: Mount Sinai Hospital, 600 University Avenue, Ontario, Canada Toronto, M5G IX5, Ontario, Canada FOREWORD Despite the increasing number of andrological pub opment of basic and clinical research in andrology, lications, the diagnostic aspects of andrology have to analyze modern techniques for the evaluation of received relatively little attention. In the last decade male infertility, to stimulate the development of substantial progress has been made in the under guideliness for therapeutic procedures, to recom standing of the fundamentals of andrology, this ment common norms of measurement, to promote progress resulting from modern techniques and and interchange of information and to stimulate the instrumentation in microanatomy, immunology, interest of scientists and clinicians in andrological neurophysiology, pathology, genetics, endocrino problems. logy, biochemistry, biophysics, urology and sur We are grateful to the authors who have given so gery. These studies are scattered in such a wide much of their time and talents to produce chapters spectrum of journals that andrologists can hardly of depth and breadth and who have made such a keep abreast of the advances. There have been significant contribution to the andrological litera textbooks on the testes, male accessory organs and ture. We are also indebted to Morag M. Smith, Lori semen but none that have attempted to bring Rust and Penny Stoops for the time and patience together the various aspects of diagnosis. Since they exhibited in typing, collation of material and in there is an increasing literature concerning diag the many editorial skills necessary to put a book nostic andrology widely scattered in many different such as this together. Finally, we would like to publications, we hope that a useful purpose will be thank Mr Jeffrey K. Smith of Martinus Nijhoff for served by summarizing the more pertinent material his excellent cooperation in the production and which can be made readily available to students and publication of this volume. practitioners of andrology. This volume is an at tempt to coordinate anatomical, physiological, bio chemical, endocrinological, radiological, cytogenic, J. BAIN Toronto, Ontario, Canada pharmacological and immunological techniques of and diagnosis and to bring together the various medical E.S.E. HAFEZ Detroit, Michigan, U.S.A. aspects of andrology. This volume is intended to encourage the devel- May, 1980 DIAGNOSIS IN ANDROLOGY

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Despite the increasing number of andrological pub­ opment of basic and clinical research in andrology, lications, the diagnostic aspects of andrology have to analyze modern techniques for the evaluation of received relatively little attention. In the last decade male infertility, to stimulate the d
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