Dermatology (Thieme Clinical Companions)

774 Pages·2006·27.242 MB·English

by  Wolfram Sterry, Ralf Paus, Walter Burgdorf

Contents
GraySection:IntroductionandDiagnosis
.....................................................................................
1 IntroductiontoSkinBiology (cid:1) 1
2 DermatologicDiagnosis (cid:1) 16
3 OtherDiagnosticMethods (cid:1) 39
BlueSection:DermatologicDiseases
.....................................................................................
4 ViralDiseases (cid:1) 53
5 BacterialDiseases (cid:1) 73
6 FungalDiseases (cid:1) 106
7 OtherInfectiousDiseases (cid:1) 122
8 SexuallyTransmittedDiseases (cid:1) 134
9 HIVInfectionandAIDS (cid:1) 155
10 AllergicDiseases (cid:1) 166
11 DrugReactions (cid:1) 179
12 Dermatitis (cid:1) 190
13 Collagen–VascularDisorders (cid:1) 203
14 AutoimmuneBullousDiseases (cid:1) 229
15 PurpuraandVasculitis (cid:1) 245
16 PapulosquamousDisorders (cid:1) 262
17 GranulomatousandNecrobioticDisorders (cid:1) 290
18 DermatosesCausedbyPhysicalandChemicalAgents (cid:1) 295
19 MetabolicDiseases (cid:1) 310
20 PruritusandPrurigo (cid:1) 328
21 Genodermatoses (cid:1) 332
22 DisordersofPigmentation (cid:1) 371
23 MelanocyticTumors (cid:1) 384
24 CystsandEpidermalTumors (cid:1) 407
25 AdnexalTumors (cid:1) 424
26 SoftTissueTumors (cid:1) 438
27 OtherCutaneousTumors (cid:1) 465
28 CutaneousLymphomasandLeukemia (cid:1) 471
29 ParaneoplasticDisorders (cid:1) 485
30 DiseasesoftheLipsandOralMucosa (cid:1) 489
31 DiseasesoftheHairsandScalp (cid:1) 495
32 DiseasesoftheNails (cid:1) 518
33 DisordersofSweatGlands (cid:1) 528
34 DiseasesofSebaceousGlands (cid:1) 530
35 DiseasesofSubcutaneousFat (cid:1) 538
36 AnogenitalDiseases (cid:1) 543
37 Phlebology (cid:1) 552
38 OccupationalDermatoses (cid:1) 565
39 SkinDiseasesinDifferentAgeGroups (cid:1) 569
40 Psychodermatology (cid:1) 579
RedSection:Therapy
.....................................................................................
41 TopicalTherapy (cid:1) 583
42 SystemicTherapy (cid:1) 615
43 RadiationTherapy (cid:1) 644
44 TherapyDuringPregnancyandNursing (cid:1) 647
45 OperativeDermatology (cid:1) 651
46 WoundHealing (cid:1) 671
47 DermatologicEmergencies (cid:1) 673
PurpleSection
.....................................................................................
AppendixI CommonSystemicMedications (cid:1) 681
AppendixII FavoriteCompoundingRecipes (cid:1) 689
GreenSection
.....................................................................................
AppendixIIIDermatologicDifferentialDiagnosis (cid:1) 702
Sterry, Dermatology © 2006 Thieme
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Sterry, Dermatology © 2006 Thieme
All rights reserved. Usage subject to terms and conditions of license.
Checklisten
der aktuellen Medizin
...............................................
BegründetvonF.Largiadèr,A.Sturm,O.Wicki
Thiseditionhasbeensupportedby
Sterry, Dermatology © 2006 Thieme
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Thieme Clinical Companions
Dermatology
...............................................
WolframSterry,M.D.
ProfessorandChairman
DepartmentofDermatology,
Venereology,andAllergy
CharitéUniversityHospital
Berlin,Germany
RalfPaus,M.D.
Professor
DepartmentofDermatologyandVenereology
UniversityHospitalSchleswig-Holstein
Luebeck,Germany
WalterBurgdorf,M.D.
ClinicalLecturer
DepartmentofDermatology
LudwigMaximilianUniversity
Munich,Germany
Withcontributionsby
HeikeAudring,UlrikeBlume-Peytavi,GuidoBruning,PetervondenDriesch,
JorgeFrank,MarkusFriedrich,ChristophGarcia-Bartels,SylkeGellrich,
InaHadshiew,MichaelHertl,WolfgangKimmig,StefanPeker,
AndreasPlettenberg,BertoldRzany,PeterSchulze,WolfgangSchulze,
UteSiemann-Harms,HansSperl,EggertStockfleth,Hans-JuergenTietz,
ClassUlrich,ChristianeVoit,GerdWolf,MargittaWorm,TorstenZuberbier
345illustrations
GeorgThiemeVerlag
Stuttgart·NewYork
Sterry, Dermatology © 2006 Thieme
All rights reserved. Usage subject to terms and conditions of license.
LibraryofCongressCataloging-in-PublicationData
SterryWolfram.
[ChecklisteDermatologie.English]
Dermatology / Wolfram Sterry, Ralf Paus, Walter Burgdorf ; with contributions by Heike
Audring...[etal.].
p.;cm.--(Thiemeclinicalcompanions)
ISBN1-58890-258-7(alk.paper)--ISBN3-13-135911-0(alk.paper)
1.Dermatology--Handbooks,manuals,etc.2.Skin--Diseases--Handbooks,manuals,etc.
[DNLM:1.SkinDiseases--therapy--Handbooks.2.Dermatology--Handbooks.3.SexuallyTransmitted
Disease--therapy--Handbooks.4.SkinNeoplasms--Handbooks.WR39S838c2006a]I.Paus,Ralf.II.
Burgdorf,WalterH.C.III.Title.IV.Series.
RL74.S815132006
616.5--dc22 2006000851
1stGermanedition1987 4thGermanedition2000
2ndGermanedition1992 5thGermanedition2005
3rdGermanedition1999
Illustrator:HelmutHoltermann,Dannenberg,Germany
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Sterry, Dermatology © 2006 Thieme
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Preface ....
Preface e
c
a
ef
WearehappytopresentyouwithournewbookDermatologyintheThiemeClinical Pr
Companionsseries.AsimilartexthasappearedinfiveGermaneditionssince1987
andbeenhighlysuccessful.Thegoalofthisbookistopresenteverythingoneneedsto
diagnoseandtreatmostcutaneousdiseasesinacompact,“one-stop”resource,care-
fullyeditedbythreeexperienceddermatologists.Thetherapeuticoptionsrepresent
bestpracticeinternationallyandreflectthediversifiedexperienceofthreedermato-
logists,oneofwhomtrainedandworkedintheUSAfor20years.
Thecontentshavebeenextensivelyreviewedwiththehelpofanumberofcolleagues
listedonthetitlepage.SomeofthemhaveprovidedadditionalinputfortheEnglish
version,includingDrs.PetervondenDriesch,BertoldRzany,ChristianeVoit,and
MargittaWorm.Inaddition,Dr.MajaHoffmannhelpedwiththedifferentialdiagnos-
ticconsiderationsinthelastchapter.WewouldespeciallyliketothankDr.GerdWolf,
whoprovidedconstructivecriticismanddetailedinformationontopicaltherapy.
Mr.StephanKonnryatThiemeInternationalguidedthewritingandproductionof
thistext.HewashelpedbyDr.CliffBergmanandDr.ChristianeBrill-Schmid.We
thankallthreeindividualsfortheircooperativespiritandvaluableinput.
WehopethatyouwillenjoyreadingthisClinicalCompanionasanintroductionto
dermatologyand,moreover,thatyoufindithelpful,ifnotindispensable,inyour
clinicaltrainingandpractice.Weareeagertohearfromyou,withcomplaints,con-
structivesuggestions,orevenpraise.
WolframSterry,M.D.
RalfPaus,M.D.
WalterBurgdorf,M.D.
V ...
Sterry, Dermatology © 2006 Thieme
All rights reserved. Usage subject to terms and conditions of license.
.... Contributors
s Contributors
r
o
t
u
rib HeikeAudring,M.D. MichaelHertl,M.D.
nt Prof.UlrikeBlume-Peytavi,M.D. ProfessorandChairman
o MarkusFriedrich,M.D. DepartmentofDermatologyand
C
ChristophGarcia-Bartels,M.D. Allergy
SylkeGellrich,M.D. PhillipsUniversity
Prof.BertoldRzany,M.D. Marburg,Germany
PeterSchulze,M.D.
StefanPeker,M.D.
HansSperl,M.D.
PrivateDermatologyPractice
Prof.EggertStockfleth,M.D.
BadSegeberg,Germany
Prof.Hans-JuergenTietz,M.D.
ClassUlrich GuidoBruning,M.D.
Prof.ChristianeVoit,M.D. TabeaHospitalHamburg
Prof.MargittaWorm,M.D. Hamburg,Germany
Prof.TorstenZuberbier,M.D.
PetervondenDriesch,M.D.
ClinicandPolyclinicforDermatology,
Professor
Venereology,andAllergy
BadCanstattHospital
Berlin,Germany
ClinicforDermatology
InaHadshiew,M.D. Stuttgart,Germany
UteSiemann-Harms,M.D.
AndreasPlettenberg,M.D.
WolfgangKimmig,M.D.
Professor
Prof.WolfgangSchulze,M.D.
InstituteofInterdisciplinary
HeadandSkinCenter
InfectiologyandImmunology
ClinicandPolyclinicforDermatology
(ifi-MedizinGmbH)
andVenereology
Hamburg,Germany
UniversityHospital
Hamburg-Eppendorf GerdWolf,M.D.
Hamburg,Germany Pharmacist
Robert-KochPharmacy
JorgeFrank,M.D.
Grafschaft-Ringen,Germany
Professor
AfdelingDermatologie
AcademischZiekenhuisMaastricht
Maastricht,TheNetherlands
... VI
Sterry, Dermatology © 2006 Thieme
All rights reserved. Usage subject to terms and conditions of license.
Contents ....
Contents s
t
n
e
GraySection:IntroductionandDiagnosis nt
..................................................................................... o
C
1 IntroductiontoSkinBiology (cid:1) 1
1.1 Overview (cid:1) 1
1.2 FunctionalAnatomy (cid:1) 1
1.3 Epidermis (cid:1) 5
1.4 Hair (cid:1) 7
1.5 BasementMembraneZone (cid:1) 8
1.6 Dermis (cid:1) 9
1.7 Subcutis (cid:1) 10
1.8 Neuroendocrine-immuneNetworking (cid:1) 11
1.9 Outlook (cid:1) 12
2 DermatologicDiagnosis (cid:1) 16
2.1 ComponentsoftheDermatologicEvaluation (cid:1) 16
2.2 DescriptionofSkinFindings (cid:1) 16
2.3 PrimaryandSecondaryLesions (cid:1) 17
2.4 AdditionalDescriptiveTerms (cid:1) 18
2.5 ToolsoftheTrade (cid:1) 22
2.6 History (cid:1) 24
2.7 HistologicDiagnosis (cid:1) 25
2.8 MolecularDiagnostics (cid:1) 32
2.9 MycologicDiagnosis (cid:1) 33
2.10 DiagnosisofHairDisorders (cid:1) 34
3 OtherDiagnosticMethods (cid:1) 39
3.1 PhlebologicDiagnosis (cid:1) 39
3.2 AllergyTesting (cid:1) 43
3.3 LightTesting (cid:1) 49
3.4 Ultrasonography (cid:1) 51
BlueSection:DermatologicDiseases
.....................................................................................
4 ViralDiseases (cid:1) 53
4.1 Overview(Table4.1) (cid:1) 53
4.2 PoxvirusInfections (cid:1) 54
4.3 HerpesvirusInfections (cid:1) 57
4.4 PicornavirusInfections (cid:1) 65
4.5 CutaneousManifestationsofHepatitisVirusInfections (cid:1) 66
4.6 HumanPapillomaviruses (cid:1) 67
5 BacterialDiseases (cid:1) 73
5.1 Introduction (cid:1) 73
5.2 Gram-positiveBacteria:Staphylococci (cid:1) 74
5.3 Gram-positiveBacteria:Streptococci (cid:1) 77
5.4 Gram-positiveBacteria:Corynebacteria (cid:1) 83
5.5 Gram-negativeBacterialInfections (cid:1) 85
5.6 MiscellaneousBacterialInfections (cid:1) 88
VII ...
Sterry, Dermatology © 2006 Thieme
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.... Contents
s 5.7 ZoonoticInfections (cid:1) 89
t
n 5.8 Borreliosis (cid:1) 92
e
t 5.9 MycobacterialInfections:Tuberculosis (cid:1) 96
n
o 5.10 MycobacterialInfections:Leprosy (cid:1) 101
C
5.11 AtypicalMycobacterialInfections (cid:1) 103
5.12 Actinomycosis (cid:1) 104
5.13 Nocardiosis (cid:1) 105
6 FungalDiseases (cid:1) 106
6.1 Nomenclature (cid:1) 106
6.2 Dermatophytes (cid:1) 106
6.3 Yeasts (cid:1) 112
6.4 SubcutaneousMycoses (cid:1) 117
6.5 SystemicMycoses (cid:1) 118
7 OtherInfectiousDiseases (cid:1) 122
7.1 Leishmaniasis (cid:1) 122
7.2 OtherProtozoanInfections (cid:1) 125
7.3 Pediculosis (cid:1) 126
7.4 Scabies (cid:1) 127
7.5 OtherEpizoonoses (cid:1) 130
7.6 Worms (cid:1) 131
8 SexuallyTransmittedDiseases (cid:1) 134
8.1 Overview (cid:1) 134
8.2 Syphilis (cid:1) 135
8.3 EndemicTreponematoses (cid:1) 145
8.4 Gonorrhea (cid:1) 146
8.5 OtherSexuallyTransmittedDiseases (cid:1) 149
9 HIVInfectionandAIDS (cid:1) 155
9.1 Overview (cid:1) 155
9.2 CutaneousManifestations (cid:1) 157
9.3 ExtracutaneousManifestations (cid:1) 161
10 AllergicDiseases (cid:1) 166
10.1 BasicMechanisms (cid:1) 166
10.2 Urticaria (cid:1) 167
10.3 Angioedema (cid:1) 173
10.4 FoodAllergies (cid:1) 174
10.5 OtherAllergicDiseases (cid:1) 176
10.6 Hyposensitization (cid:1) 176
11 DrugReactions (cid:1) 179
11.1 Overview (cid:1) 179
11.2 CommonReactions (cid:1) 182
11.3 SevereSkinReactions (cid:1) 184
11.4 UncommonReactions (cid:1) 186
11.5 DrugPseudoallergies (cid:1) 188
12 Dermatitis (cid:1) 190
12.1 AtopicDermatitis (cid:1) 190
12.2 SyndromesAssociatedwithAtopicDermatitis (cid:1) 194
... VIII
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