Dental Neuroimaging: The Role of the Brain in Oral Functions

323 Pages·2022·30.469 MB·English

by  Chia-shu Lin

13.8 mm 178 x 254 mm
LIN
Provides the latest neuroimaging-based evidence
on the brain mechanisms of oral functions
DENTAL
Dental Neuroimaging: The Role of the Brain in Oral Functions provides an up-to-date
overview of neuroimaging research on the neural mechanisms underlying mastication,
swallowing, sensory processing, and other oral topics.
Divided into three parts, the book first introduces the theoretical framework of the NEUROIMAGING
brain-stomatognathic axis, clinical assessments for oral function, and neuroimaging
methods. The second part presents recent neuroimaging findings of oral sensory and
motor functions such as somatosensation, gustation, and orofacial pain and anxiety.
D
The book concludes with a review of recent translational research and discussion of
E
the application of neuroimaging in clinical management. Throughout the text, boxed
N THE ROLE OF THE BRAIN IN ORAL FUNCTIONS
sections highlight key information about cognitive neuroscience, imaging techniques,
interpreting neuroimaging results, and relating research findings to clinical practice. T
A
• Covers specific clinical applications of dental neuroimaging in geriatric
L CHIA-SHU LIN
dentistry and in brain plasticity and adaptation

N
• Summarizes classic research works in neuroscience and oral science
E
• Discusses potential clinical applications of neuroimaging in dental practice
U
• Features chapter summaries, further reading links, guided clinical scenarios,
and numerous figures and tables R
O
Offering a systematic introduction to brain science and how it relates to dental medicine,
I
Dental Neuroimaging: The Role of the Brain in Oral Functions is essential reading for M
students and researchers in disciplines such as neuroscience, neuroanatomy, oral
A
physiology, dentistry and oral healthcare, speech therapy, and oral rehabilitation.
G
I
N
Chia-Shu Lin, Professor, Department of Dentistry, National Yang Ming Chiao Tung
University (NYCU), Taiwan. Dr Lin is one of the few researchers specializing in both G
clinical dentistry and human brain science, focusing on neuroimaging. His current
work explores the brain mechanisms of oral sensorimotor functions and the cognitive-
affective processing of pain and dental anxiety.
Accompanied by a companion website at www.wiley.com/go/lin/dental-neuroimaging
featuring video content and supplementary resources.
Cover Design: Wiley
Cover Images: Courtesy of Chia-Shu Lin; © KJ_Photography/Shutterstock
www.wiley.com/go/dentistry
0005217271.INDD 6 11/19/2021 09:40:23
Dental Neuroimaging
0005217271.INDD 1 11/19/2021 09:40:22
0005217271.INDD 2 11/19/2021 09:40:22
Dental Neuroimaging
The Role of the Brain in Oral Functions
Chia- Shu Lin
Department of Dentistry
National Yang Ming Chiao Tung University
Taipei, Taiwan, Republic of China
0005217271.INDD 3 11/19/2021 09:40:22
This edition first published in 2022
© 2022 John Wiley & Sons Ltd
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any
form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice
on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.
The right of Chia- Shu Lin to be identified as the author of this work has been asserted in accordance with law.
Registered Offices
John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, USA
John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK
Editorial Office
9600 Garsington Road, Oxford, OX4 2DQ, UK
For details of our global editorial offices, customer services and more information about Wiley products, visit us at
www.wiley.com.
Wiley also publishes its books in a variety of electronic formats and by print- on- demand. Some content that appears
in standard print versions of this book may not be available in other formats.
Limit of Liability/Disclaimer of Warranty
The contents of this work are intended to further general scientific research, understanding and discussion only,
and are not intended and should not be relied upon as recommending or promoting scientific method, diagnosis or
treatment by physicians for any particular patient. In view of ongoing research, equipment modifications, changes
in governmental regulations and the constant flow of information relating to the use of medicines, equipment and
devices, the reader is urged to review and evaluate the information provided in the package insert or instructions
for each medicine, equipment or device for, among other things, any changes in the instructions or indication of
usage and for added warnings and precautions. While the publisher and authors have used their best efforts in
preparing this work, they make no representations or warranties with respect to the accuracy or completeness
of the contents of this work and specifically disclaim all warranties, including without limitation any implied
warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales
representatives, written sales materials or promotional statements for this work. The fact that an organization,
website or product is referred to in this work as a citation and/or potential source of further information does not
mean that the publisher and authors endorse the information or services the organization, website or product
may provide or recommendations it may make. This work is sold with the understanding that the publisher is not
engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your
situation. You should consult with a specialist where appropriate. Further, readers should be aware that websites
listed in this work may have changed or disappeared between when this work was written and when it is read.
Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including
but not limited to special, incidental, consequential or other damages.
Library of Congress Cataloging- in- Publication Data
Names: Lin, Chia-Shu, 1976– author.
Title: Dental neuroimaging : the role of the brain in oral functions /
Chia-Shu Lin.
Description: Hoboken, NJ : Wiley-Blackwell, 2022. | Includes
bibliographical references and index.
Identifiers: LCCN 2021047940 (print) | LCCN 2021047941 (ebook) | ISBN
9781119724209 (paperback) | ISBN 9781119724254 (Adobe PDF) | ISBN
9781119724230 (epub)
Subjects: MESH: Stomatognathic System–diagnostic imaging |
Neuroimaging–methods | Brain Mapping–methods
Classification: LCC RK308 (print) | LCC RK308 (ebook) | NLM WU 102 | DDC
617.5/22–dc23
LC record available at https://lccn.loc.gov/2021047940
LC ebook record available at https://lccn.loc.gov/2021047941
Cover Design: Wiley
Cover Images: Courtesy of Chia-Shu Lin; © KJ_Photography/Shutterstock
Set in 9.5/12.5pt STIXTwoText by Straive, Pondicherry, India
10 9 8 7 6 5 4 3 2 1
0005217271.INDD 4 11/19/2021 09:40:23
This book is dedicated to my parents, for their love and caring, my wife, I-t ing, and our
children, Yuan- han and Yi-h sien, who are my inspiration.
0005217271.INDD 5 11/19/2021 09:40:23
0005217271.INDD 6 11/19/2021 09:40:23
vii
Contents
List of Figures x
List of Tables xviii
List of Boxes xx
List of Abbreviations xxi
Preface xxiii
Introduction to Students and Instructors xxiv
Acknowledgements xxv
About the Companion Website xxvi
Part I Methods of Neuroimaging and Assessment of Oral Functions 1
1 Introduction to Neuroimaging and the Brain–Stomatognathic Axis 3
1.1 Why Do Dentists Need to Understand the Brain? 3
1.2 What Is Neuroimaging? 6
1.3 How Does Neuroimaging Contribute to Clinical Practice? 15
1.4 The Brain–Stomatognathic Axis 17
Further Readings 21
References 22
2 Assessment of Human Brain Using MRI 25
2.1 Advantages and Limitations of Magnetic Resonance Imaging of the Brain 25
2.2 Research of Task-b ased Functional Activation 30
2.3 Research of Structural Features of the Brain 39
2.4 Research of Brain Connectivity 45
Further Readings 56
References 56
3 Assessment of Oral Functions 59
3.1 Assessment of Masticatory and Swallowing Performance 59
3.2 Assessment of Orofacial Pain and Somatosensory Experience 68
3.3 Assessment of Cognitive Functions and Emotional Experience 77
Further Readings 81
References 81
0005217272.INDD 7 11/19/2021 09:42:01
viii Contents
Part II Neuroimaging Research of Brain Mechanisms of Oral Functions 89
4 Brain Mechanisms of Oral Motor Functions 91
4.1 Introduction of Brain Mechanisms of Motor Control 91
4.2 Brain Mechanisms of Human Mastication 98
4.3 Brain Mechanisms of Human Swallowing 109
4.4 Cognitive Processing and Motor Learning of Oromotor Movement 116
Further Readings 120
References 121
5 Brain Mechanisms of Oral Sensory Functions 128
5.1 Brain Mechanisms of Oral Somatosensory Processing 128
5.2 Brain Mechanisms of Gustation 136
5.3 Cognitive–Affective Issues of Oral Sensory Functions 141
5.4 Brain Mechanisms of Multisensory Integration 149
Further Readings 154
References 154
6 Brain Mechanisms of Pain and Anxiety of Dental Patients 161
6.1 Brain Mechanisms Related to Pain 161
6.2 Chronic Pain, Neural Plasticity and Central Sensitization 170
6.3 Brain Mechanisms of Chronic Orofacial Pain 178
6.4 Brain Mechanisms of Dental Fear and Anxiety 191
Further Readings 199
References 200
Part III Translational Research of Dental Neuroimaging 213
7 Age- related Differences in the Brain–Stomatognathic Axis 215
7.1 Age- related Differences in Brain Mechanisms 215
7.2 Age- related Changes in Oral Sensorimotor Functions 220
7.3 Association Between the Brain and Oral Functions in Older People 229
7.4 Association Between Oral Conditions and Neurodegenerative Disorders 235
Further Readings 245
References 245
8 Brain Mechanisms of Adaptation of Oral Sensorimotor Functions 254
8.1 Brain Plasticity and Adaptation 254
8.2 Adaptation of Pain and Oral Sensory Functions 260
8.3 Functional Adaptation of Mastication and Swallowing 266
8.4 Brain Plasticity Associated with Oral Functional Training 271
Further Readings 275
References 275
0005217272.INDD 8 11/19/2021 09:42:01