Cytopathology (Encyclopedia of Pathology) PDF
Preview Cytopathology (Encyclopedia of Pathology)
Encyclopedia of Pathology Series Editor: J.H.J.M. van Krieken Fernando Schmitt Editor Cytopathology Encyclopedia of Pathology SeriesEditor J.H.J.M.vanKrieken Thescopeofthis15–20-volumesetencompassestheentirefieldofpathology ranging from general pathological terms to specific diseases to diagnostic methods. Published as print edition and online version (eReference) in the Springer Reference Program each volume sticks out by clearly and homo- genouslystructuredentries.Ateamofinternationalexpertsguaranteethatthe essays and definitions are scientifically sound. The A-Z format allows searchingfor a word while the reader does not need toknow towhat patho- logicalspecialitythetermbelongsto.Themajoradvantageoftheencyclope- diaisthewayitmakesrelevantinformationavailablenotonlytopathologists, but also to all clinicians and researchers of the neighbouring disciplines working together with pathologists who occasionally might wish to look up termsonline. Moreinformationaboutthisseriesathttp://www.springer.com/series/14876 Fernando Schmitt Editor Cytopathology With 649 Figures and 15 Tables Editor FernandoSchmitt Laboratoirenationaldesanté LuxembourgCity,Luxembourg MedicalFacultyofPortoUniversityandIPATIMUP Porto,Portugal ISBN978-3-319-33285-7 ISBN978-3-319-33286-4 (eBook) ISBN978-3-319-33287-1(printandelectronicbundle) DOI10.1007/978-3-319-33286-4 LibraryofCongressControlNumber:2017936961 #SpringerInternationalPublishingAG2017 Thisworkissubjecttocopyright.AllrightsarereservedbythePublisher,whetherthewholeor part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations,recitation,broadcasting,reproductiononmicrofilmsorinanyotherphysicalway, andtransmissionorinformationstorageandretrieval,electronicadaptation,computersoftware,or bysimilarordissimilarmethodologynowknownorhereafterdeveloped. Theuseofgeneraldescriptivenames,registerednames,trademarks,servicemarks,etc.inthis publicationdoesnotimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexempt fromtherelevantprotectivelawsandregulationsandthereforefreeforgeneraluse. Thepublisher,theauthorsandtheeditorsaresafetoassumethattheadviceandinformationinthis bookarebelievedtobetrueandaccurateatthedateofpublication.Neitherthepublishernorthe authorsortheeditorsgiveawarranty,expressorimplied,withrespecttothematerialcontained hereinorforanyerrorsoromissionsthatmayhavebeenmade.Thepublisherremainsneutralwith regardtojurisdictionalclaimsinpublishedmapsandinstitutionalaffiliations. Printedonacid-freepaper ThisSpringerimprintispublishedbySpringerNature TheregisteredcompanyisSpringerInternationalPublishingAG Theregisteredcompanyaddressis:Gewerbestrasse11,6330Cham,Switzerland Dedicated to Els, Lotte, Bas and Wouter who are my inspiration J.H.J.M. van Krieken ThiSisaFMBlankPage Series Preface WhenDenisDiderotstartedthefirstencyclopediaintheeighteenthcentury,it wasagroundbreakingandtimelyevent.ItwasthetimeoftheEnlightenment, andknowledgewasseenassomethingwhichwastobespreadtomanyandto builduponbycreatingnewknowledge.Hisambitionwastobringallavailable knowledgetogetherinoneseriesofbookssothateverypersonwhocouldread has access to all there is to know. Nowadays, in a time of easily accessible knowledge,thequestioniswhetherthereisstillneedofanencyclopedia.Itis obviousthattheamountofknowledgeissuchthatitisnotpossibletobringit all together in one encyclopedia. One may argue that the Internet is the encyclopediaoftoday,butthatmissesanimportantpointofDiderot,apoint that is probably even more valid today. He created a team that valued infor- mationandselectedwhatwasworthtobepresentedintheencyclopedia.He recognizedthatscienceisnotademocraticprocesswherethemajoritydecides whatistrueandvaluable,butratheragrowing bodyofknowledgeinwhich radical ideas from individuals may bring about huge changes, even though mostwouldrejectthesenewideasinthebeginning.Indeed,theInternetlacks suchauthorityanditisnoteasytoselectvaluableinformationfromnonsense, especiallywhenoneisnotanexpertinacertainfield. Itisthereforethatanencyclopediaisonlyasgoodastheteamthatcreates it.ItgoeswithoutsayingtheteamthatisresponsiblefortheEncyclopediaof Pathologyconsistsofrecognizedexpertsinthefield.Pathologyisagrowing medical discipline in which the amount of information is probably already more than that the whole encyclopedia of Diderot contained. For experts in subspecialties within pathology, it is already almost impossible to keep an overviewonnewdevelopmentsandtoselectrelevantfromlessrelevantnew information. There are plenty of textbooks for every disease group, and scientific literature is available for most pathologists through PubMed or Google Scholar. What is lacking is a systematic overview of what we know inanalphabeticalorder,easilyaccessibletoall.Theencyclopediaofpathology fillsthatgap.Itiswrittenbyexpertswiththegeneralpathologistinmindand alsospecialistfromotherdisciplines.Itwillconsistofaseriesofvolumeson subspecialties, and when it is completed there will be an online version combining these. Yearly updates from the online version is foreseen and readers are welcome to provide suggestions for improvement. These will be judgedbytheeditorialteaminordertokeeptheencyclopediaauthoritativeyet usingtheexpertiseofmany. vii viii SeriesPreface Finally,itismyhopethattheencyclopediawillgrowintoareliablebodyof knowledge in pathology, enabling communication through a common lan- guage,andthatitwillgrowandadapttonewdevelopments. Nijmegen,TheNetherlands J.H.J.M.vanKrieken March2017 Volume Preface The practice of cytopathology has undergone significant evolution in the last 50years.Cytopathologyisactuallyconsideredadiagnosticmethodmorethana screeningmethodinmostoftheareasthatitisappliedandisanintegralpartof pathology.Furthermore,inthelastyearstheincorporationofnewtechnologieson cytologymaterial,asmoleculartechniques,hasbeenessentialindrivingclassifi- cationoftumorsandprovidingprognosticandpredictiveinformation.However, whenmoreweadvanceforthemoleculardiagnosticmoreweobservethevalueof agoodandprecisemorphologicalevaluationofthespecimens.Inthisencyclope- dia, we cover all of main areas where a cytological interpretation/diagnosis is possible.Thereareatotalof210chapters,coveringdifferentpathologicalentities, revisingclinicalandcytomorphologicalaspects,aswellaswithcommentsabout ancillary techniques, including immunocytochemistry and molecular findings. The chapters are well illustrated with representative pictures that will help the readerthatusestheencyclopedia.Mostofthemoreexperiencedcytopathologists aroundtheworldcontributedforthisbookbringingtheirpersonalprofessional andteachingexperience.Thiswillbeagreatvalueforthegeneral,specialist,and forthetraineepathologistsintheirdailypractice.Iwouldliketothankpersonally allthecontributorsofthisencyclopediafortheirtimeandavailabilityinsharing theirknowledgewithourreaders.Knowledgeinmedicineisadvancingveryfast in different scientific domains. Image guidance, less invasive procedures, and availability of cells or tissues from patients are crucial for disease diagnosis, identificationof moleculartargets,and study ofprognosticfactors. Thismakes cytologytohaveacentralroleinmodernmedicine.Thedynamicaspectofthe encyclopedia,asalivingplatformthatcanincorporateupdatesandincorporate newentriesinanongoingbasis,fitsperfectlywiththecurrentspeedofcreationof new knowledge in medicine, pathology, and cytopathology. I hope that this encyclopediacanserveourreaderstoobtainhelpfulinformationforbetterdiag- nosisandmanagementofthepatients.Nowitistimetoenjoythetextandthe illustrationsofthisbookthatpresentstheup-to-dateknowledgeincytopathology. Laboratoirenationaldesanté FernandoSchmitt,MD,PhD,FIAC LuxembourgCity,Luxembourg MedicalFacultyofPorto UniversityandIPATIMUP Porto,Portugal ix
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