Current Topics in Contact Dermatitis

616 Pages·1989·13.67 MB·English

by  Ph.D., T. Chu, M. Shaw, J. Elliot, A. Dash (auth.), Prof. Dr. med. Peter Frosch, A. Dooms-Goossens P.Ph., J.-M. Lachapelle M. D., Dr. R. J. G. Rycroft, Dr. R. J. Scheper (eds.)

P. J. Frosch, A. Dooms-Goossens,
J.-M. Lachapelle, R. J. G. Rycroft, R. J. Scheper
(Editors)
Current Topics in
Contact Dermatitis
On behalf of the European Environmental and Contact Dermatitis
Research Group (EECDRG)
K. E.Andersen (Roskilde) J.-M. Lachapelle (Louvain)
C. Benezra (Strasbourg) A. Lahti (Oulu)
D. Burrows (Belfast) T. Menne (Copenhagen)
J. G. Camarasa (Barcelona) R.J. G. Rycroft (London)
A. Dooms-Goossens (Leuven) R. J. Scheper (Amsterdam)
G. Ducombs (Bordeaux) I. R. White (London)
P.J. Frosch (Heidelberg) J. D. Wilkinson (High Wycombe)
Springer-Verlag Berlin Heidelberg New York
London Paris Tokyo Hong Kong
Editors:
Prof. Dr. med. Peter Frosch
Hautklinik der Universitat Heidelberg
Vo£stra£e 2
6900 Heidelberg 1, FRG
A. Dooms-Goossens, P. Ph., Ph. D.
Department of Medical Research (Dermatology)
Katholieke Universiteit Leuven
3000 Leuven, Belgium
J-M.Lachapelle, M.D.
Professor of Dermatology
Unit and Laboratory of Occupational and Environmental Dermatology
Catholic University of Louvain
30, Clos Chapelle-aux-Champs, DCL 3033
1200 Brussels, Belgium
Dr. R.J G. Rycroft
St.john's Hospital for Diseases of the Skin
Lisle Street
London WC2H 7BJ, Great Britain
Dr. R.J Scheper
Department of Pathology, Free University Hospital
de Boelelaan 1117
1081 HV Amsterdam, The Netherlands
Library of Congress Cataloging in Publication Data.
Current topics in contact dermatitis / P.J.Frosch ... let al.) (editors). Papers presented
at a symposium sponsored by the European Environmental and Contact Dermatitis Research
Group, held in Heidelberg, Germany in May 1988.
Bibliography: p. Includes index.
ISBN 978-3-642-74301-6 ISBN 978-3-642-74299-6 (eBook)
DOI 10.1007/978-3-642-74299-6
1. Contact dermatitis-Congresses.
I. Frosch, Peter J. II. European Environmental and Contact Dermatitis Research Group.
RC593.C6C88 1989 616.5'1-dc20 89-6418 CIP
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Preface
In recent years the field of contact dermatitis has increased greatly in
importance in dermatology. The variety of exogenous, environmental-
ly caused dermatoses has undoubtedly expanded over the past few de-
cades with the increasing number of potentially toxic chemicals, the
changes in lifestyle, and the greater life expectancy in industrialized
societies.
The value of international cooperation in this field has long been
realized and acted upon by the International Contact Dermatitis Re-
search Group (ICDRG). By 1975 the international journal Contact
Dermatitis had been founded under the editorship of C. D. Calnan.
Thanks largely to the ICDRG and Contact Dermatitis, there were, by
1986, enough additional dermatologists and scientists with a special
interest in this area to form the European Environmental and Contact
Dermatitis Research Group (EECDRG). Within 2 years they had in-
stituted the European Society of Contact Dermatitis (ESCD) as an in-
ternational forum for researchers in the field.
The EECDRG decided to hold a symposium in Heidelberg in May
1988, an initiative supported by the ICDRG, and on this occasion the
new ESCD held its inaugural session. The Society already has over
200 members and most national contact dermatitis research groups in
Europe are already represented; new members are of course welcome.
Subgroups and working committees have been formed to address var-
ious topics including the standardization of patch testing, photoder-
matology, and bioengineering.
The symposium included a large number of presentations covering
virtually all aspects of contact dermatitis of current interest. This book
contains almost all these papers and thus reflects the multiple facets of
research activity in the field of contact dermatitis today. To speed pub-
lication, the papers have not been reviewed in detail. However, before
acceptance for the symposium all abstracts submitted were reviewed
by a committee of five members of the EECDRG. '
We hope that this volume will prove to be a valuable source of ref-
erence and stimulate further research. The next symposium of the
ESCD will be held in Brussels in 1992.
January 1989 The Editors
Table of Contents
Part 1
The Basics (Immunological Aspects)
Allergic Contact Dermatitis: Carrier Proteins for Nickel 3
T. Chu, M. Shaw, J. Elliott, and A. Dash
Allergic Contact Dermatitis: T-Cell Receptors and Migration 12
R. J. Scheper and B. M. E. von Blomberg
Epidermal Mediators for LYl11phocytes in Contact Eczema 19
C. G. Larsen, T. Ternowitz, and K. Thestrup-Pedersen
Evidence for the Existence of Prohapten-Activating Enzyme 24
in the Skin: Induction of Contact Sensitivity
to Monocrotaline in Mice
R.J.Schmidt and L.Khan
Part 2
Morphological Aspects
Light- and Electron-Microscopic Morphology 33
of Contact Urticaria
J. Daroczy and E. Temesvari
The Occurrence of Different Morphological Parameters 38
in Allergic and Irritant Patch Test Reactions
C. Avnstorp, E. Balslev, and H. K. Thomsen
Preliminary Findings on the Patterns of Epidermal Damage 42
Induced by Irritants in Man
C.M.Willis, C.J.M.Stephens, and J.D.Wilkinson
VIII Table of Contents
Part 3
Current Contact Allergens
lSj7itien1iolo~)l
Contact Dermatitis 1988: Historical Reflections 50
and Current Prolems in Patch-Testing
J. M. Lachapelle
Epidemiology of Contact Allergic Dermatitis in Croatia 57
J. Lipozenci6, A. Kansky, Z. Peris, and A. Wolf
Patch Tests in Mycosis Fungoides 61
v. Ziegler, E. Temesvari, C. Quednow, G. Richter, U. Nagel,
K. Schlenzka, and N. Berowa
Lymphomatoid Contact Dermatitis 66
A. Alomar, R. M. Pujol, A. Tuneu, and A. Moreno
Patch Testing in Children 73
N. Balato, G. Lembo, C. Patruno, and F.Ayala
Contact Dermatitis with Multiple Sensitization 80
in an 8-Year-Old Child
M.A. Barros, A. Baptista, and F.Amado
Antin1icrobials anti Preservatives
Contact Allergy to Preservatives 84
K. E. Andersen
Occupational Skin Sensitization to the Antimicrobials 88
ortho-Benzyl para-Chlorophenol and Ampholyte 103 G
T. Estlander, L. Kanerva, and R. Jolanki
Contact Sensitivity to Diazolidinylurea (Germall II) 92
C. M. Perret and R. Happle
Occupational Contact Dermatitis from Glutaraldehyde 95
Used as a Cold Sterilizing Agent
M. Nelis and J. Oleffe
Anaphylactic Allergy to Chlorhexidine Cream 99
P. Susitaival and L. Hakkinen
Table of Contents IX
Contact Sensitivity to Nonoxynols: 104
A Cause of Intolerance to Antiseptic Preparations
A. Dooms-Goossens, A. Gidi de Alam, and H. Degreef
Preservatives in Geneva 108
F. Pasche and N. Hunziker
Industrial Dermatitis Due to Kathon CG and 112
1-Chloro-Hydroxy-3: 6: 8: 11 : 14 Pentaoxahexadecane
(Acticide BG)
T. P. Kingston, R J. G. Chalmers, and M. H. Beck
Sensitization to Kathon CG in Switzerland: Report of the 115
Swiss Contact Dermatitis Research Group
N. Hunziker, F. Pasche, L. Bruckner-Tuderman, D. Perrenoud,
R Rufli, A. Bircher, H. Suter, and W. ThOrliman
Fragrances
Data Generation for Perfume Ingredient Safety Evaluation 122
M.A. Cooke, P. A. Cadby, and RG.Harrison
Preliminary Results on the Effectiveness 127
of Two Forms of Fragrance Mix as Screening Agents
for Fragrance Sensitivity
J. D. Wilkinson, K. Andersen, J. Camarasa, G. Ducombs,
P. Frosch, A. Lahti, T. Menne, R. J. G. Rycroft, and I. White
Rubber
Condoms and Rubber Allergy: A Preliminary Report 133
of a New "Hypoallergenic" Condom
M. Rademaker and A. Forsyth
Carba Mix: A Useful Indicator of Rubber Sensitivity 136
M. Rademaker and A. Forsyth
Plants
Contact Sensitivity to Anthemis Plants 141
L. Fernandez de Corres, I. Leanizbarrutia, and D. Munoz
Allergic Contact Dermatitis from Silver Birch Pollen 146
G. M. Murphy and RJ. G. Rycroft
X Table of Contents
Occupational Contact Dermatitis Due 149
to Codiaeum variegatum L., Chrysanthemum indicum L.,
Chrysanthemum x hortorum and Frullania dilatata L.
M.-B. Cleenewerck and P. Martin
Allergic Contact Dermatitis to Ginkgo biloba L.: 158
Relationship with Urushiol
J.-P. Lepoittevin, C. Benezra, and Y. Asakawa
Contact Dermatitis from Ficus carica 163
G.Angelini, G.A.Vena, and C.L.Meneghini
Metals
Intracutaneous Testing in Doubtful Cases of Contact Allergy 169
to Metals
H.Molier
Is Nickel Vasculitis a Clinical Entity? 172
N. K. Veien and A. Krogdahl
Preliminary Results of a Multicenter Study on the Incidence 178
of Nickel Allergy in Relationship to Previous Oral
and Cutaneous Contacts
I. M. W. van Hoogstraten, K. E. Andersen, B. M. E. von Blomberg,
D. Boden, D. P. Bruynzeel, D. Burrows, J. M. G. Camarasa,
A. Dooms-Goossens, G. Kraal, A. Lahti, T. Menne,
RJ.G.Rycroft, D.Todd, K.J.J.Vreeburg, J.D.Wilkinson, and
R J. Scheper
Nickel Sensitivity in Schoolchildren in Finland 184
L. Peltonen and P. Terho
Nickel Allergy and Ear Piercing in Young Men 188
L. Widstrom and I. Erikssohn
Nickel Dermatitis in Construction Workers 191
H.J.Schubert, H.Luck, and E.Auermann
An Investigation of Patients with a History of Nickel Allergy 195
but Negative Epicutaneous Patch Tests
D.J.Todd, D.Burrows, and C.F.Stanford
Bioimplantation of Metals in Patients with Metal Allergy: 199
The Late Outcome
H. Moller and A. Carlsson
Table of Contents XI
Cobalt, Nickel and PPD Sensitivity 203
in Housewives' Hand Dermatitis
J. Vilaplana, F. Grimalt, and C. Romaguera
Metalworking Fluids and the Skin 208
E. M. de Boer, W. G. van Ketel, and D. P. Bruynzeel
Cutting Oil Dermatitis: A Review of 115 Patients 212
J. S. C. English and R.J. G. Rycroft
Medicaments
Contact Hypersensitivity in Patients 217
with Chronic Otitis Externa
P. K. Buxton, D. G. Keay, and I. M. Smith
Mafenide - Still an Allergen of Importance? 222
R. Breit and P. Seifert
Systemic Drugs and Palmar Eczema 226
B.Edman
Cutaneous Reactions to Estraderm 229
R.M.Adams
Corticosteroid Contact Allergy: A Reality 233
A.Dooms-Groossens, H.Degreef, and S. Coopman
Drug-Induced Dermatitis with Acetonides of Corticoids 238
O. M. Maucher, H. Knipper, and M. Faber
Optimal Testing for Contact Allergy 244
to Topical Corticosteroids
S. Reitamo, A. I. Lauerma, and L. Forstrom
Cross Allergy to Non-Steroidal Antiphlogistic Drugs 248
U. Beller
Acute Generalized Dermatitis to Orally Administered 250
Disulfiram
E.van Hecke
XII Table of Contents
Relevant Allergens in Perianal Contact Dermatitis 254
K.-P. Peters, A. Heese, and H. Hahn
Bacitracin and Polymyxin B: 258
Important Contact Allergens in Patients with Leg Ulcers
D. Kleinhans
Contact Dermatitis to Minoxidil 261
J. G. Camarasa, E. Serra-Baldrich, B. Garcia-Bravo,
and J. F. Vozmediano
Contact Lens Intolerance, Astigmatism, and Atopy 264
P. Guerra, A. Aguilar, and A. Garcia-Perez
Allergic Contact Conjunctivitis Due to Ophthalmic Solutions 269
A. Tosti and G. Tosti
Various Allergens
Formaldehyde and Glyceryl Monothioglycolate: Results of 274
the German Contact Dermatitis Research Group
P. J. Frosch, D. Kleinhans, T. Fuchs, A. Schnuch, H.lppen,
J. Ring, B. Przybilla, J. Rakoski, A. Stary, H. Merk, G. Lischka,
J. Brasch, F. Bahmer, and G. Goerz
Comparative Patch Testing with PPD-Base 281
and PPD-Dihydrochloride: Human and Animal Data
Compiled by the European Environmental Contact
Dermatitis Research Group
A. Dooms-Goossens, R.J.Scheper, K. E.Andersen,
D. Burrows, J. G. Camarasa, P. J. Frosch, A. Lahti,
and J. Wilkinson
Colour Developing Agents: High-Performance Liquid 286
Chromatography Analysis of Test Preparations Used
in Guinea Pig Maximization Testing
C. Liden, A. Boman, and J.Sollenberg
Contact Dermatitis and Vitiligo Due to Colour Developers 291
F. M. Brandao, A. Dinis, and R. Silva
Thiourea Contact Sensitivity in Portugal 294
A.Azenha, F.M.Brandao, M.S.J.Marques, M.Pecegueiro,
A. Pinto Soares, G. Saudade, A. Sousa Basto, and T. Vale
Allergic Contact Dermatitis from the Insecticide Dichlorvos 298
J.de la Cuadra and G.Serrano