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CURRENT Medical Diagnosis & Treatment 2018 PDF

1953 Pages·2018·57.419 MB·English
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s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p PLACEHOLDER FOR MARKETING PAGE s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p CMDT2018_FM_pi-xvi.indd 1 07/07/17 5:50 PM s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e This page intentionally left blkank e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p CMDT2018_FM_pi-xvi.indd 2 07/07/17 5:50 PM s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p a LANGE medical book s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o m e e/ /e e b 2018m e e/ /e e b m e e/ /e e b m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p Ch ht ttUt p RRENT h ht tt t p s Medical Diagns osis s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o e b b o & Treatme eb b no t e b b o m e e/ / e m e e/ / e m e e/ / e m m m h ht tt tp ps s: /: // t/ .t . h ht tt tp ps s:F/:I//Ft/T.t Y. - S E V E N T H E D I T I O N h ht tt tp ps s: /: // t/ .t . Edited by s s s r s r s r s e r e r e r o k k e Maxine A. Papadakis,o MDk k e o k k e b o o o Professor of Medibcineo, Eomeroitus b o o o e b Departmeent of Mbedicine e b m e e/ / e Univmersitye oef /Ca/lifoernia, San Francisco m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . Stephen J. McPhee, MD p s s: /: // t/ .t . h ht tt t p h ht tt t p DivPisrioofnes osfo Gr oefn Mereadl Iincitneern, Eaml Meeridtuicsine h ht tt t p Department of Medicine University of California, San Francisco Associate Editor s s s r s r s r s e r e r e r k e Michael W. Rabow, MDk e k e o k o k o k b o o o Professor of Medicibne aondo Uroology b o o o e b Division of Geneeral Intbernal Medicine e b m e e/ / e mDepearet/m/ente of Medicine m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/U.tn.iversWitiyt ho fA Cssaolifcoiarnteia A, Suathno Frrsancisco p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o o o k New York Chicago San Francisco Athenso Loonodon k Madrid Mexico City o o o k b o Milan New Delhi Singapbore oSydney Toronto b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p CMDT2018_FM_pi-xvi.indd 1 07/07/17 5:50 PM s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p Copyrigrht s©s 2018 by McGraw-Hill Education. All rights reserved. Except as permitted runsdesr the United States Copyright r s s e r e r e r kAct ofe 1976, no part of this publication may be reproduced or distributed in any fokrm or eby any means, or stored in a database k e o k o k o k o o or retrieval system, without the prior written permission of the publisher.o o o o b o b o b o e b e b e b m e e/ / e ISBN: 978-1-25-986149-9 m e e/ / e m e e/ / e m MHID: 1-25-986149-X. m m p s s: /: // t/ .t . The material in this eBook also pappesarss: in/: t//het/ p.trin.t version of this title: ISBN: 978-1-25-986148-2, p s s: /: // t/ .t . h ht tt t p MHID: 1-25-986148-1h.ht tt t p h ht tt t p eBook conversion by codeMantra Version 1.0 All trademsarks are trademarks of their respective owners. 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TIMHPEL WIEODR, KIN VCILAU HDYINPGE RBLUINT KpN OORTs sLO:ITM/:HI/E/TREt/WD.t ITS.OE , IAMNPDL I EEDX PWRAERSRSLAYN TDIIESSC LOAFI MM EARNCYH WAANRTARBAINLTITYY, EOXRPp RFEITSsNSsE :OS/:RS // t/ .t . h ht tt t p FcoOnRta Ain ePdA iRnT thICe UwLoArkR wh PilhUl tmRttPeeOtt SyEop.u Mr rceGquriarwem-Heinltls E odru tchaatti oitns aonpde riattsi olinc ewnislol rbse d uon ninotte rwruaprrtaendt oorr egruroarr afnreteehe. Nhthteaitttt hthetre MfpucnGctriaowns- Hill Education nor its licensors shall be liable to you or anyone else for any inaccuracy, error or omission, regardless of cause, in the work or for any damages resulting therefrom. McGraw-Hill Education has no responsibility for the content of any information accessed through the work. 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Tehis rlimr itastion of liability shall apply to e r r s k e k e k e o anky claim or cause whatsoever whether such claim or cause arises in contracot, tort okr otherwise. o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r Contents e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e Authors m e e/ v/ e 14. Disorders of Hemostasis, Thrombosis, & m e e/ / e m m m p s s: /: // t/ .t . P r1e.f aDcei sease Preventiopn &s Hs:ea/:lt//ht /P.tro.motion xi1ii AAnndtriethwr Do.m Lebaovtititc, MThDe, r&a Tpryac y Minichpiellos, Ms:D/:5 5//3t/ .t . h ht tt t p Michael Pignhohnte, ttMtD, MpPH, & René Salazar, MD 15. Gastrointestinal Disordehrsh t tt t p 586 2. Common Symptoms 19 Kenneth R. McQuaid, MD Paul L. Nadler, MD, & Ralph Gonzales, MD, MSPH 16. Liver, Biliary Tract, & Pancreas r s s Disorders r s s 685 r s s k e e3. r Preoperative Evaluation & Perioperative k e e r k e e r o o o k Management 45 oLaowroencek S. Friedman, MD o o o k b o b o b o m e e/ /e e b Hugo Q. Cheng, MD m e e/ /e e 1b7. Breast Disorders 746 m e e/ /e e b p s s: /: // t/ .t . m 4. GG.e Mriiacthraiecl DHiasropredr, eMrpDs , Cs. Bs:ree/: J//oht/n.tsto.n,m MD, MP5H5, 18. GArymnaencdool oEg. Giciu Dliaisnoor, dMeDr,s & Sara A. Hpurvistz,s :M/:D7 7//1t/ .t . m h ht tt t p & C. Seth Lanhdhetfettld,t MpD Jason Woo, MD, MPH, FACOGh ht tt t p 5. Palliative Care & Pain Management 72 19. Obstetrics & Obstetric Disorders 805 Michael W. Rabow, MD, Steven Z. Pantilat, MD, Scott Steiger, MD, & Ramana K. Naidu, MD Vanessa L. Rogers, MD, & Scott W. Roberts, MD s s s k e e6r. rDesrmatologic Disorders 100 20. Rheumk ateoleorgirc, sImmunologic, k e er r s o k & oAllergkic Disorders 834 o k o o Kanade Shinkai, MD, PhD, & Lindy P. Fox, MD o o o o b o b o b o e b e b David B. Hellmann, MD, MACP, & e b m e e/ / e 7. Disorders of the Eyes & Lids m e 1e/70/ e John B. Imboden Jr., MD m e e/ / e m m m h ht tt tp ps s: /: // t/ .t . 8. EPaaur,l NRioosrdea, nh&-E hTvthart,t oFtRapCt OpDpsihssto:hr d/:e//rst/ .t . 205 21. EKelerrcyt Cro. Clyhtoe, M&D A cid-Base Dhishotrttdetprsp s s: /:89//3t/ .t . Lawrence R. Lustig, MD, & Joshua S. Schindler, MD 22. Kidney Disease 922 9. Pulmonary Disorders 246 Tonja C. Dirkx, MD, Tyler Woodell, MD, & Suzanne Watnick, MD Asha N. Chesnutt, MD, Mark S. Chesnutt, MD, & s s s e r rThsomas J. Prendergast, MD 23. Urologic eDisrorrdesrs 962 e r r s k e k e k e o k o k o k o o 10. Heart Disease 328 oMaxwoell V. Meng, MD, FACS, o o e b b o e b b Tohomas J. Walsh, MD, MS, & Thomas D. Chi, MD e b b o mme e/ / e TKheovimn aPs. JMa.c Bkassohno, rMe,D M, D&, MCharnisetsohp hRe. rP Ba.t Gemlr,a mMngDe er, Me/D,/ e 24. Nervous System Disorders 986 mme e/ / e p s s: /: // t/ .t . 11. Systemic Hypertepnsiosns: /: // t/ .t . 447 MVaicnhjaa eCl. JD. oAumgilnaosf, fM, MDD , DSc, FRCP, & p s s: /: // t/ .t . h ht tt t p Michael Suttherhst, MttDt, MpRCP (UK) h ht tt t p 25. Psychiatric Disorders 1059 12. Blood Vessel & Lymphatic Disorders 479 Kristin S. Raj, MD, Nolan Williams, MD, & Warren J. Gasper, MD, Joseph H. Rapp, MD, & Charles DeBattista, DMH, MD Meshell D. Johnson, MD s s s r s 26. Endocrine Drisordsers 1117 r s e r e r e r o k k 1e3. Blood Disorders 507 Paoul A.k Fiktzgeerald, MD o k k e o o o o o o b o Lloyd E. Damon, MD, & b o b o e b e b e b m e e/ / e Charalambos Andreadis, MD, MSCE m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . iii p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p CMDT2018_FM_pi-xvi.indd 3 07/07/17 5:50 PM s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p iv CMDT 2018 CONTENTS s s s r s r s r s 27. Deiabetres Mellitus & Hypoglycemia 1222 40. Genetic & Genoemic Drisorders 1690 e r k e k e k e o k o k o k o o Umesh Masharani, MB, BS, MRCP(UK) Reed Eo. Pyeriotz, MD, PhD o o b o b o b o e b e b e b m e e/ / e 28. Lipid Disorders 1m269 e e4/1/. Seports Medicine & m e e/ / e m m Outpatient Orthopedics 1699 m h ht tt tp ps s: /: // t/ .t . 29. NRRooubbteerrrittt iBBo.. nBBaaarrl ooDnni,,s MMoDDrhd,, MMehrtSSs tt tp ps s: /: // t/ .t 1.278 42. LAensthboianyn L, uGkaey, M, BDi,s MexPuHa, &l, C&. BTerannjasmghienhn Mtdatte, rMt pDp s s: /: // t/ .t . Health 1731 30. Common Problems in Infectious Diseases & Juno Obedin-Maliver, MD, MPH, MAS, Patricia A. Antimicrobial Therapy 1297 Robertson MD, Kevin L. Ard, MD, MPH, Kenneth H. s Mayer, MD, & Madeline Bs. Deutsch, MD, MPH s Peterr V. Chsin-Hong, MD, & r s r s e r e r e r k B. Joeseph Guglielmo, PharmD k e k e o k e1. Anti-Infeoctive kChemotherapeutic & o k o o o o o o e b b o 31. HIV Infection & AIDS 1340 eAnbtibbiootic Agents Online* e b b o m e e/ / e Mitchell H. Katz, MD m e e/ / eB. Joseph Guglielmo, PharmD m e e/ / e m m m p s s: /: // t/ .t . 32. Viral & Rickettsial Infectiponss s: /: // t/ .t 1.378 e2. DMiaakginnogs tic Testing & Medical DecisioOnn plines*s: /: // t/ .t . h ht tt t p NWaatyanliee XJ.. SMh.a Dnadielerya ,Gh MahDrtn etts, tMDp, MPH, & C. Diana Nicoll, MD, PhD, MPA, & h ht tt t p Chuanyi Mark Lu, MD 33. Bacterial & Chlamydial Infections 1455 e3. Information Technology Brian S. Schwartz, MD in Patient Care Online* s s s r s r s r s 34k. Sepierocrhetal Infections 1501 Russ Cucina, MkD, MeSe r k e e r o k o k o k o o o o o o b o Susan S. Philip, MD, MPH e4. Inbtegraotive Medicine Online* b o e b e b e b m e e/ / e 35. Protozoal & Helminthic Infections 1m519 e e/ / eKevin Barrows, MD m e e/ / e m m m p s s: /: // t/ .t . Philip J. Rosenthal, MD p s s: /: // t/ .t . e5. Podiatric Disorders Onplines*s: /: // t/ .t . h ht tt t p 36. Mycotic Infectionhs ht tt t p 1560 Monara Dini, DPM h ht tt t p Samuel A. Shelburne, III, MD, PhD, & e6. Women’s Health Issues Online* Richard J. Hamill, MD Megan McNamara, MD, MSc, & 37. Disorders Related to Environmental Judith Walsh, MD, MPH Emerrgesnscies 1574 r s s r s s e r e r e r o k kJacqeueline A. Nemer, MD, FACEP, & e7. Appendixo: Thkekrapeeutic Drug Monitoring & o k k e b o o o Marianne A. Juarez, MD Labboroatooryo Reference Intervals, & b o o o e b ePhabrmacogenetic Testing Online* e b m e e/ / e 38. Poisoning 1m590 e e/ / eC. Diana Nicoll, MD, PhD, MPA, & m e e/ / e m m m p s s: /: // t/ .t . Kent R. Olson, MD p s s: /: // t/ .t . IndexC huanyi Mark Lu, MD p175s1s: /: // t/ .t . h ht tt t p 39. Cancer h ht tt t p 1620 h ht tt t p Patricia A. Cornett, MD, & Tiffany O. Dea, PharmD s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e *Free access to online chapters at www.accessmedicinem.com/ecmed/t/ e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p CMDT2018_FM_pi-xvi.indd 4 07/07/17 5:50 PM s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p s s s r s r s r s e r Authors e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m N. Franklin Adkinson, Jr., MD m David M. Barbour, PharmD, BCPS m p s s: /: // t/ .t . ProAfellsesrogry o Cf eMnetedri,c Binaelt, iJmohopnres, HMsoapsr:kyilna/:ns/ /dA t/sth.tm.a & Pdbhaarrbmoaucri9st9,@ Dgemnvaeilr.,c Comolorado p s s: /: // t/ .t . h ht tt t p fAaldlekrignisco &@ jIhmmmiu.endhoulohgtictt Dtisoprders (in Chapter 20) Drug References h ht tt t p Robert B. Baron, MD, MS Diana Alba, MD Professor of Medicine; Associate Dean for Graduate and Fellow, Division of Endocrinology and Metabolism, Continuing Medical Education; University of University of California, San Francisco California, San Francisco s s s Rerferencses [email protected] r s e r e r e r k e Lipid Disordkers; Nuetritional Disorders k e o o o k Michael J. Aminoff, MD, DSc, FRCP o o o k o o o k e b b o Distinguished Professor and Executive Vice Chair, e bKbevino Barrows, MD e b b o m e e/ / e Department of Neurology, University of Camliforneia,e / / e Clinical Professor of Family and Community Medicine, m e e/ / e m San Francisco; Attending Physician, Universimty of Director of Mindfulness Programs, Osher Center for m p s s: /: // t/ .t . micChaaleiflo.armniian Moffe@diuccaslf C.edenupter, Ssans: Fr/:an//cit/sc.to . ICnotemgmrautinveit yM Medeidciicnien;e D, Uepnaivrtemrseitnyt ooff CFaamlipfiolryn asina,ds : /: // t/ .t . h ht tt t p Nervous System Dhisohrtdettrs t p KevSiann. BFarrarnocwissc@ou csf.edu h ht tt t p Timothy S. Anderson, MD, MA CMDT Online—Integrative Medicine Research Fellow, Division of General Internal Medicine, Department of Medicine, University of California, Thomas M. Bashore, MD San Francisco Professor of Medicine; Senior Vice Chief, Division of Rerferesncses Cardiology, Duker Unsivsersity Medical Center, Durham, r s s e r e r e r k e North Carkolina e k e o o o k Charalambos Babis Andreadis, MD, MSCE [email protected] o o o k e b b o Associate Professor of Clinical Medicine, Division of e bHbearto Disease e b b o mme e/ / e HSaenm Fartaonlocgisyc/oO ncology, University of Califomrnmia, e e/ / e Hugo Q. Cheng, MD mme e/ / e p s s: /: // t/ .t . CBlhoaorda [email protected]: /: // t/ .t . CliSnaicna Fl rParnocfeisscsoor of Medicine, University ofp Calsifos:rn/:ia,// t/ .t . h ht tt t p Kevin L. Ard, MhDh, tMttPtH p qPureionpneyr.achtievne [email protected] & Perioperahtivhet Mttatnagpement Faculty, Division of Infectious Diseases, Massachusetts General Hospital; Medical Director, National LGBT Asha N. Chesnutt, MD Health Education Center, Fenway Institute; Instructor Clinical Assistant Professor, Division of Pulmonary & in Medicine, Harvard Medical School, Boston, Critical Care Medicine, Department of Medicine, Masssachusetts s s r s Oregon Health &r Sciensce University, Portland, Oregon r s k [email protected] [email protected] k e e r o o o k Gay & Bisexual Men’s Health (in Chapter 42) Pulmoonoaryo Diskorders o o o k b o b o b o m e e/ /e e b NCliicnhicoall aFse lAlorwg, eDre, pMarDtment of Pulmonary, Cmritical eCaer/e, /e e Mbark S. Chesnutt, MD m e e/ /e e b m m Professor, Pulmonary & Critical Care Medicine, Dotter m h ht tt tp ps s: /: // t/ .t . RAenfASetarolenleni nrFcgereyas ,nE ac.n iAsdc zoSa lehre,p hM tMDttedtipcinpes, Us:niv/:er//sit/ty. tof. California, cheIUPsnonntreuitvrtlevamrnes@nditt oyiVoh, enPstuaeol.rre atIdlnnaussnt Aidt,uf fOtaeir,r eOsg Horeneg;ao Dlnthi hrH Ceechaattroletrhtt ,S Cy&tpsr tiSetpicmciaes ln sCc:ea r/:e,// t/ .t . Pulmonary Disorders Assistant Professor of Medicine, Division of Allergy & Clinical Immunology, Johns Hopkins Asthma & Allergy Center, Baltimore, Maryland [email protected] s s r s r s r s eAllerrgic & Immunologic Disorders (in Chapter 20) e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . v p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p CMDT2018_FM_pi-xvi.indd 5 07/07/17 5:50 PM s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p vi CMDT 2018 AUTHORS s s s r s r s r s Thomeas D.r Chi, MD Tiffany O. Dea, PharemD, Br COP e r k e k e k e oAssisktant Professor, Department of Urology, University of Oncology Pharmoacist, kVeterans Affairs Health Care o k o o o o o o b o California, San Francisco Systebm, Sano Francisco, California; Adjunct Professor, b o e b e b e b m e e/ / e tUormol.ocghiic@ Duicssofr.edderus m e e/ /TSchieoenmcaess ,J .S Ltoocnkgto Snc,h Coaolli foofr Pnhiaa rmacy and Health m e e/ / e m m m h ht tt tp ps s: /: // t/ .t . PPreoMtfeeesrds Voicr.i, n CDeh,i viUnisni-oiHvneo ronsfi gtIyn, foMefhc CDtihaotluifstto Drtnpisiaep,a Ssseasns, :DFr/:eapn//acrit/tsmc.toe n.t of tCCifahfnaancreylr.edse [email protected], DMH, MD h ht tt tp ps s: /: // t/ .t . [email protected] Professor of Psychiatry and Behavioral Sciences; Director, Common Problems in Infectious Diseases & Antimicrobial Depression Clinic and Research Program; Director of Therapy Medical Student Education in Psychiatry, Stanford University School of Medicine, Stanford, California Kerry C. Chso, MD [email protected] s s r s r s r s Cliknicael Peroferssor of Medicine, Division of Nephrology, Psychiatric Disordersk e e r k e e r m e e/ /e eb bo ookEoelerUcrtynrk.ocivlhyeotre@s i&tuyc Asofcf. eiCdd-auBliafoser nDiais, oSradne rFsrancisco m e eMA/ s/asMeodceeeidalbiticeni bnPeer o;Bo Df.oe Disroseeocorut ootrsf, ckCUhlCi,n SMiFca DTl rFaanmsgileyn &de Cr Comarme; uCneitnyt er of m e e/ /e eb bo oo o k m m m p s s: /: // t/ .t . PCelinliinca Cl iAnsasirs,t aMntD P, rMofeSssor of Medpicinse isn: O/:n//cot/lo.tgy., MaECdxaeclliiefnloleer.nnDiceaeu, fStosacrn hT @Frrauancnsscgfi.eesncddouer Health, University of p s s: /: // t/ .t . h ht tt t p UQnuiavleitrys iItmy pofr oCvaelmifoernnt,i aUh SChaSntF Ftt Hratenlecpnis cDoi;l lDeri rFeacmtoirl yo f Transgender Health & Disease Prevention (inh Chhtaptttetr 4p2) Comprehensive Cancer Center Monara Dini, DPM [email protected] Assistant Clinical Professor, Chief of Podiatric Surgery Alimentary Tract Cancers (in Chapter 39) Division, Department of Orthopedic Surgery, Patricia Ar. Csosrnett, MD University of California, Srans Frsancisco r s s e r [email protected] e r e r Prokfessore of Medicine, Division of Hematology/Oncology, k e k e o k CMDT Online—oPodiatkric Disorders o k o oUniversity of California, San Francisco o o o o b o b o b o e b [email protected] Toneja C.b Dirkx, MD e b m e e/ / e Cancer m e eA/ s/soceiate Professor of Medicine, Division of Nephrology, m e e/ / e m m m p s s: /: // t/ .t . RPruosfess sCour coifn Hao, sMpiDta,l MMeSdicine; Chpief Hsesa:lth/: I//nft/or.tm.ation DUDnievpiivaseirortsmnit eCyn, hPti oeofrf, t MlPaonerddti,l caOinnrdee ,gV Ooentree; rgAaoncntsi nHAgef faNaliterhps h&Hr eoSalcolitgehny C pcea res s: /: // t/ .t . h ht tt t p OSafnfi cFerra, nUciCscSoF Health Shysthetmtt; Utnipversity of California, System h ht tt t p [email protected] [email protected] Kidney Disease CMDT Online—Information Technology in Patient Care Vanja C. Douglas, MD Natalie J. M. Dailey Garnes, MD, MPH Assistaent Prrorfsesssor, Department of Infectious Diseases, SarNa e&u rEovhaons pWitiallliisatm Csh Faoieru, nAdrsastorisocinas tEe nPdroowfeesdso r of Clinical e r rs s kInfectieon Control, and Employee Health, Division of k e k e o k Neurology, Doepartmkent of Neurology, University of o k mme e/ /e eb bo o nVojidrIAaanlin tl&eedrye n@Rrasimolc knMde atCetndsadiinaceclir neIsnreo ,fnC eTc.eothniroegt enUrs, n Hivoeurssittoyn o, fT Texeaxsas MD mme eVN/ae/nrCevjaaoel.uiDfsboo Srubnygsiotalae, msoS@a Dunc ioFssorf.raedndecuriss co mme e/ /e eb bo o o p s s: /: // t/ .t . Lloyd E. Damon, MD p s s: /: // t/ .t . PCalinuilc Aal .P Friotfzegsseorr aolfd M, MedDicine, Department of Medipcine,s s: /: // t/ .t . h ht tt t p ProDfeivssisoiro nof o Cf lHineimcaal tMoleodgiyhc/iOnhetn,c Dttoletopgaypr;t mDiernetc toofr M ofe dAidciunlet , DSainv iFsiroann coifs cEon docrinology, University of hChaltifottrntia,p Hematologic Malignancies and Blood and Marrow [email protected] Transplantation, Deputy Chief of the Division of Endocrine Disorders Hematology and Medical Oncology, University of California, San Francisco Lindy P. Fox, MD [email protected] r s s r s s e r Associate Professor, Depeartmernt of Dermatology, e r Blokod Diseorders k e k e o k University of oCaliforknia, San Francisco o k o o o o o o b o [email protected] b o m e e/ /e e b m e eD/ e/remeatolobgic Disorders m e e/ /e e b m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p CMDT2018_FM_pi-xvi.indd 6 07/07/17 5:50 PM s s s r s r s r s e r e r e r k e k e k e o k o k o k o o o o o o b o b o b o e b e b e b m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p AUTHORS CMDT 2018 vii s s s r s r s r s eLawrrence S. Friedman, MD G. Michael Haerper,r MD e r k e k e k e o k Professor of Medicine, Harvard Medical School; Professor Professoor, Diviksion of Geriatrics, Department of Medicine, o k o o o o o o b o of Medicine, Tufts University School of Medicine, b Unoiversity of California San Francisco School of b o e b e b e b m e e/ / e BCohsatior,n D, Mepaasrstamcheunst eotft sM; Tehdeic Ainnet,o Nne Rw.t oFnri-eWdm,e MlleDsl,ee y e/ / e MSyestdeimcin, Se;a nSa Fnr aFnracnisccios,c oC aVleiftoerrnanias Affairs Health Care m e e/ / e m m m h ht tt tp ps s: /: // t/ .t . lfriHMMedoeamsdspsiaacintcian@hle,up ,Ns aMerettwtansst eshoransch.,ho tMurgtstaesttstpas cGpheusnseestr:tasl/:; HA//ossst/ipsti.ttaan.l,t BCohsiteofn o,f MGDeaircvihaiatdrei lcB.H D. aHirspeoerldrlm@erusa cnsfn.e,d MuD, MAChPht tt tp ps s: /: // t/ .t . Liver, Biliary Tract, & Pancreas Disorders; Hepatobiliary Aliki Perroti Professor of Medicine; Vice Dean for Johns Cancers (in Chapter 39) Hopkins Bayview; Chairman, Department of Medicine, Johns Hopkins Bayview Medical Center, Johns Hopkins Warren J. Gasper, MD University School of Medicine, Baltimore, Maryland Asrsistsanst Professor of Clinical Surgery, Division of [email protected] s s r s s k e e Varscular and Endovascular Surgery, Department of Rheumatologkic, Iememunrologic, & Allergic Disorders k e e r m e e/ /e eb bo oo o k wBlaoSroruder ngV.egersayss,ep lU e&rn@ iLvuyecmrssfipt.heyda outifc C Dailsifoorrdneiras, San Franmcisco e e/ /e ebSAbassDrooaicv oiAiastoi.eo HnPo ruoorff vekHsisetomzr,;a MDtoilDroegcyto/Or, nBcroelaosgt yO, Dnceoplaorgtym Pernot gorfa m, m e e/ /e eb bo oo o k m m m p s s: /: // t/ .t . AExremcuatnivde oV iEce. GCihualiira onf oSu, prMgeDrsy, ,F sAA:sCs/:oSc//,i aFt/tRe.t CD.SirEedctor of sBhrueIarnsvttei trDzn@iaslmo Mrdedeerdnsiecti.nuec,l aU.endivuersity of Californiap, Loss As:ng/:ele//st/ .t . h ht tt t p SLuorsg Aicnagl eOlensc, oClhoalgihyfot, rCntteidat arsp-Sinai Medical Center, John B. Imboden, Jr., MD h ht tt t p [email protected] Alice Betts Endowed Chair for Arthritis Research; Breast Disorders Professor of Medicine, University of California, San Francisco; Chief, Division of Rheumatology, Ralph Gonzales, MD, MSPH s Zuckerberg San Franscisco General Hospital s eAsrsorciaste Dean, Clinical Innovation and Chief Innovation [email protected] e r r s o k k e Officer, UCSF Health; Professor of Medicine, Division Rheumaotologkick, Imemunologic, & Allergic Disorders o k k e o o of General Internal Medicine, Department of Medicine, o o o o b o b o b o e b University of California, San Francisco e Kbevin P. Jackson, MD e b m e e/ / e [email protected] m e e/ / e Assistant Professor of Medicine, Director of m e e/ / e m Common Symptoms m Electrophysiology, Duke Raleigh Hospital, m p s s: /: // t/ .t . Christopher B. Grangepr, MsDs: /: // t/ .t . DNourkteh U Cnairvoelrinsiaty Medical Center, Durhamp, s s: /: // t/ .t . h ht tt t p ProDfeusksoe rU onf iMveersdiithcyi nhMet;e dDttiictraelc pCtoern, tCear,r dDiuack eC Carlein Uicnailt , kH.ej@ardtu Dkies.eeadsue h ht tt t p Research Institute, Durham, North Carolina Jane Jih, MD, MPH, MAS [email protected] Heart Disease Assistant Professor of Medicine, Division of General Internal Medicine, Department of Medicine, s s s eB.r Jor sesph Guglielmo, PharmD University of eCalirforrnisa, San Francisco e r r s o k k Perofessor and Dean, School of Pharmacy, University of Referencoes k k e o k k e o o o o o o e b b o California, San Francisco e bMbeshoell D. Johnson, MD e b b o m e e/ / e BCJoomsempohn.G Purgolbielelmmso @inu Icnsffe.cetdiouus Diseases & Anmtimicreobeia/l / e Associate Professor of Medicine, Division of Pulmonary m e e/ / e m m and Critical Care Medicine, Department of Medicine, m p s s: /: // t/ .t . TChheermaoptyh; eCraMpDeuTti cO &nl iAnnep—tibAionsttiics- :IAng/:feecn//ttisvt/e .t . meUshneilvl.ejroshitnys oofn [email protected], San Francisco p s s: /: // t/ .t . h ht tt t p Richard J. Hamhilhl,t MttDt p Blo(oAdl cVoehsosleils m&) L (yinm Cphhaatpicte Dr i2s5o)r dersh; Ahltcothtotl Upse Disorder Professor, Division of Infectious Diseases, Departments of Medicine and Molecular Virology & Microbiology, C. Bree Johnston, MD, MPH Baylor College of Medicine, Houston, Texas Medical Director of Palliative and Supportive Care, [email protected] PeaceHealth St. Joseph Medical Center, Bellingham, Mycostic Infections s s r s Washington; Clinrical Psrofessor of Medicine, r s e r e r e r k e Universityk of Weashington k e o k o k o k o o [email protected] o o e b b o e bGberiatoric Disorders e b b o m e e/ / e m e e/ / e m e e/ / e m m m p s s: /: // t/ .t . p s s: /: // t/ .t . p s s: /: // t/ .t . h ht tt t p h ht tt t p h ht tt t p CMDT2018_FM_pi-xvi.indd 7 07/07/17 5:50 PM

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