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Current Diagnosis & Treatment Obstetrics & Gynecology PDF

1087 Pages·2018·1111.251 MB·English
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a LANGE medical book CURRENT Diagnosis & Treatment Obstetrics & Gynecology 12TH EDITION Alan H. DeCherney, MD Neri Laufer, MD Chief, Reproductive Endocrinology and Gynecology Branch Department of Obstetrics and Gynecology National Institute of Child Health and Hadassah University Hospital Human Development Ein Kerem National Institutes of Health Jerusalem, Israel Bethesda, Maryland Ashley S. Roman, MD, MPH Lauren Nathan, MD Associate Professor Professor Director, Division of Maternal Fetal-Medicine Department of Obstetrics and Gynecology NYU School of Medicine The David Geffen School of Medicine at UCLA NYU Langone Health Los Angeles, California New York, New York New York Chicago San Francisco Athens London Madrid Mexico City New Delhi San Juan Singapore Sydney Toronto Copyright© 2019 by McGraw-Hill Education. All rights reserved. Except as permitted under the United States Copyright Act of 1976, no part oft his publication may be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without the prior written permission of the publisher. ISBN: 978-0-07-183391-2 MHID: 0-07-183391-9 The material in this eBook also appears in the print version of this title: ISBN: 9780-0-71-83390-5, MHID: 0-07-183390-0. eBook conversion by codeMantra Version 1.0 All trademarks are trademarks of their respective owners. Rather than put a trademark symbol after every occurrence of a trade marked name, we use names in an editorial fashion only, and to the benefit of the trademark owner, with no intention of infringe ment of the trademark. Where such designations appear in this book, they have been printed with initial caps. McGraw-Hill Education eBooks are available at special quantity discounts to use as premiums and sales promotions or for use in corporate training programs. To contact a representative, please visit the Contact Us page at www.mhprofessional.com. Notice Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publisher of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they disclaim all responsibility for any errors or omissions or for the results obtained from use of the information contained in this work. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this work is accurate and that changes have not been made in the recommended dose or in the contraindications for administration. This recommendation is of particular importance in connection with new or infrequently used drugs. TERMSOFUSE This is a copyrighted work and McGraw-Hill Education and its licensors reserve all rights in and to the work. Use of this work is subject to these terms. Except as permitted under the Copyright Act ofl 976 and the right to store and retrieve one copy of the work, you may not decompile, disassemble, reverse engineer, reproduce, modify, create derivative works based upon, transmit, distribute, disseminate, sell, publish or sublicense the work or any part ofit without McGraw-Hill Education's prior consent. You may use the work for your own noncommercial and personal use; any other use of the work is strictly prohibited. Your right to use the work may be terminated ify ou fail to comply with these terms. THE WORK IS PROVIDED "AS IS." McGRAW-HILL EDUCATION AND ITS LICENSORS MAKE NO GUARANTEES OR WARRANTIES AS TO THE ACCURACY, ADEQUACY OR COMPLETENESS OF OR RESULTS TO BE OBTAINED FROM USING THE WORK, INCLUDING ANY INFORMATION THAT CAN BE ACCESSED THROUGH THE WORK VIA HYPERLINK OR OTHERWISE, AND EXPRESSLY DISCLAIM ANY WARRANTY, EXPRESS OR IMPLIED, INCLUD ING BUT NOT LIMITED TO IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. McGraw-Hill Education and its licensors do not warrant or guarantee that the functions contained in the work will meet your requirements or that its operation will be uninterrupted or error free. Neither McGraw-Hill Education nor its licensors shall be liable to you or anyone else for any inaccuracy, error or omission, regardless of cause, in the work or for any damages resulting therefrom. McGraw-Hill Education has no responsibility for the content of any information accessed through the work. Under no circumstances shall McGraw-Hill Education and/or its licensors be liable for any indirect, incidental, special, punitive, consequential or similar damages that result from the use of or inability to use the work, even if any of them has been advised of the possibility of such damages. This limitation of liability shall apply to any claim or cause whatsoever whether such claim or cause arises in contract, tort or otherwise. Contents Authors vii 1o . The Normal Puerperium 190 Preface xv Caroline Pessel & Ming C Tsai Sedion I. Reprodudion Basics 11. Imaging in Obstetrics 214 1. Anatomy of the Female Simi Gupta & Ashley S. Roman Reproductive System 1 Sedion Ill. Pregnancy at Risk Carter M. Owen & Ryan J. Heitmann 12. Assessment of At-Risk Pregnancy 223 2. Embryology of the Urogenital System & Congenital Anomalies Shobha H. Mehta & Robert J. Sokol of the Genital Tract 38 13. Early Pregnancy Risks 234 Catherine M. DeUgarte Ann-Marie Surette & Samantha M. Dunham 3. Genetic Disorders Br Sex Chromosome Abnormalities 67 14. Late Pregnancy Complications 250 Somjate Manipalviratn, Bradley Trivax, Ashley S. Roman Andy Huang, Aaron M. Rosen, & Laura Zalles 15. Congenital Fetal Infections 267 4. Physiology of Reproduction Unzila Nayeri & Stephen F. Thung in Women 97 Connie Alford & Sahadat K. Nurudeen 16. Disproportionate Fetal Growth 292 Jeannine Rahimian 5. The Breast 119 Amer Karam 17. Multifetal Gestation 303 Margaret Dziadosz & Ashley S. Roman Sedion II. Normal Obstetrics 18. Third-Trimester Vaginal Bleeding 311 6. Normal Pregnancy Br Prenatal care Sarah A. Wagner Helene B. Bernstein 19. Malpresentation & Cord Prolapse 318 7. Normal & Abnormal Labor &Delivery 156 Karen Kish Terri-Ann Bennett Christine Proudfit & 20. Operative Delivery 335 Ashley S. Roman Marc H. lncerpi 8. Maternal Physiology During 21. Postpartum Hemorrhage Br Pregnancy Be: Fetal Be: Early the Abnormal Puerperlum 350 Neonatal Physiology 164 Amy A. Flick & Daniel A. Kahn Sarah B. H. Poggi 22. Neonatal Resusdtation 369 9. Normal Newborn Assessment & care 181 Elisabeth L Raab & Lisa K. Kelly Elisabeth L Raab & Lisa K. Kelly iii CONTENTS 23. Critical Care Obstetrks 388 35. Hematologic Disorders In Pregnancy 550 Nathan S. Fox, Johanna Weiss, & Ramada S. Smith Christina Arnett, Jeffrey S. Greenspoon, & Ashley S. Roman a 24. Obstetric Analgesla Anesthesia 412 Section V. General Gynecology John S. McDonald, Biing-Jaw Chen, & Wing-Fai Kwan 36. Gynecologic History, Examination, a Diagnostk Procedures 563 Section IV. Surgical & Medical Complications of Pregnancy Charles Kawada & Drorith Hochner-Celnikier 25. Surgkal Disorders in Pregnancy 433 37. Imaging in Gynecology 582 Ella Speichinger & Christine H. Holschneider Meghan C. Ozcan, Alan H. DeCherney, & Micah J. Hill 26. Hypertension in Pregnancy 454 a 38. Pediatrk Adolescent Gynecology 589 Jonathan Y. Rosner & Shi/pi S. Mehta-Lee Dvora Bauman 27. cardiac Disorders In Pregnancy 466 a 39. Complications of Menstruation Jennifer Duffy & Afshan B. Hameed Abnormal Uterine Bleeding 621 28. Pulmonary Disorders in Pregnancy 477 Asher Shushan Martin N. Montoro 40. Benign Disorders of the Vulva &Vagina 631 29. Renal & Urinary Tract Disorders In Pregnancy 491 Jacob Bornstein Nathan S. Fox & Andrei Rebarber 41. Benign Disorders of the Uterine Cervix 658 30. Gastrointestinal Disorders In Pregnancy 501 Chetna Arora, Izabel/a Khachikyan, & Pamela Stratton Chad K. Klauser & Daniel H. Saltzman 42. Benign Disorders of the 31. Dermatologic Disorders Uterine Corpus 675 In Pregnancy 509 Michael P. Dougherty & Alan H. DeCherney Abigail Ford Winkel 43. Benign Disorders of the a a 32. Diabetes Mellitus Pregnancy 516 Ovaries Oviduds 687 Aisling Murphy &C arla Janzen OferLavie 33. Thyroid & Other Endocrine 44. Urinary Incontinence a Disorders During Pregnancy 526 Pelvic Floor Disorders H7 Cynthia Gyamfi-Bannerman Christopher M. Tarnay, Andrew R. Medendorp, Seth A. Cohen, & Patricia J. Mwesigwa a 34. Nervous System Autoimmune Disorders in Pregnancy 45. Sexually Transmitted Diseases & Pelvic Infections 734 Laura Kalayjian, T. Murphy Goodwin, & Richard H. Lee Grace E. Whiteley CONTENTS 46. Antimicrobial Chemotherapy 765 Sedion VII. Reproductive Endocrinology & Infertility Shmuel Benenson 55. Infertility 917 47. Perioperative, lntraoperative, Br Postoperative Complications Cheryl Yondorf, Shahin Ghadir, in Gynecologk Surgery 785 Goyane Ambansumyan, & Alan H. DeCherney Cecilia K. Wieslander &K yle Bukowski 56. Amenorrhea 928 48. Therapeutic Gynecologic Procedures 804 Alex Simon, Wendy Y. Chang, & Alan H. DeChemey Cecilia K. Wieslander, Tracy N. Hadnott, & Kyle Bukowski 57. Hirsutism 939 Sedion VI. Gynecologic Oncology Matan Elami-Suzin & Ariel Revel 58. Endometriosis 950 49. Premallgnant Br Malignant Disorders of the Vulva Br Vagina 823 Assaf Ben-Meir & Susan Sarajari Amer Karam 59. Assisted Reprodudive Technologies: In Vitro Fertilization Ir 50. Premalignant Br Malignant Related Techniques 959 Disorders of the Uterine Cervix 837 Konstantinos G. Michalakis, Lisa M. Garcia &C hristine H. Holschneider Alan H. DeCherney, & Alan S. Penzias 51. Premalignant Br Malignant 60. Contraception Br Family Planning 968 Disorders of the Uterine Corpus 863 Ronald T. Burkman & Amnon Brzezinski Mana Baskovic & Oliver Dorigo 61. Menopause Br Postmenopause 989 52. Premalignant Br Malignant Disorders of the Ovaries Br ovtducts 882 Lauren W. Sundheimer & Lauren Nathan Thalia R. Segal & Baruch S. Abittan Sedion VIII. Psychological & Social Issues 53. Gestational Trophoblastic Diseases 897 Paola Aghajanian &8 . J. Rimel 62. Domestic Violence Br Sexual Assault 1015 54. Radiation and Chemotherapy Michael C. Lu, Jessica S. Lu, Vivian P. Ha/fin, & for Gynecologk Cancers 908 Jessica Y. Hsu Wafic M. EIMasri & Oliver Dorigo Index 1023 This page intentionally left blank Authors Baruch S. Abittan, MD Cynthia Gyamfi-Bannerman, MD, MSc Premalignant & Malignant Disorders Ellen Jacobson Levine and Eugene Jacobson Professor of uf the Ovaries & Oviducts Women's Health in Obstetrics and Gynecology Director, Maternal-Fetal Medicine Fellowship Program Paola Aghajanlan, MD Co-Director, CUMC Preterm Birth Prevention Center Associate Professor of Obstetrics New York, New York and Gynecology Thyroid & Other Endocrine Disorders During Pregnancy Maternal-Fetal Medicine Cedars-Sinai Medical Center Dvora Bauman, MD Los Angeles, California Director, Bat-Ami Center Gestational Trophoblastic Diseases Adolescent Gynecology, Pediatric & OB/GYN Hadassah University Hospital Connie Alford, MD, FACOG Jerusalem, Israel Associate Physician Pediatric & Adolescent Gynecology IVFMD Naples, Florida Shmuel Benenson, MD, MSc Physiology of Reproduction in Women Head, Unit for Infection Prevention and Control Department of Clinical Microbiology and Gayane Ambartsumyan, MD, PhD Infectious Diseases Reproductive Partners Medical Group Hadassah-Hebrew University Medical Center Redondo Beach, California Jerusalem, Israd Infertility Antimicrobial Chemotherapy Christina Arnett, MD Terri-Ann Bennett, MD Department of Obstetrics & Gynecology Assistant Clinical Professor of Obstetrics and Gynecology University of Southern California Division of Maternal-Fetal Medicine Medical Center New York University Langone Hospital-Brooklyn Los Angdes, California New York, New York Hematologic Disorders in fugnan9 Normal & Abnormal Labor & Delivery Chetna Arora, MD Assaf Ben-Meir, MD Minimally-Invasive Gynecology Department of Obstetrics and Gynecology Surgery Fellow Hadassah Medical Center and Columbia University Medical Center Hebrew University-Hadassah Medical School New York. New York Jerusalem, Israd Benign Disorders oft he Uterine Cervix Endometriosis Mana Baskovic, DO Helene B. Bernstein, MD, PhD Obstetrics & Gynecology Resident, PGY-3 Associate Professor Stanford University Obstetrics and Gynecology, Microbiology and Immunology Stanford, California SUNY Upstate Medical University fumalignant & Malignant Syracuse, New York Disorders uf the Uterine Corpus Normal fugnan')' & Prenatal Care vii viii AUTHORS Jacob Bornstein, MD, MPA Alan H. DeCherney, MD Professor and Chairman, Chief, Reproductive Endocrinology and Gynecology Branch Department of Obstetrics & Gynecology National Institute of Child Health and Human Galilee Medical Center and Azrieli Faculty of Medicine, Development Bar Ilan University National Institutes of Health Nahari.ya, Israel Bethesda, Maryland Benign Disorders of the Vulva & Vagina Imaging in Gynecology; Benign Disorders oft he Uterine Corpus; Infertility; Amenorrhea; Amnon Brzezinski, MD Assisted Reproductive Technologies: In Vivo Director Fertilization & Related Techniques Womens Health Center Professor catherine M. DeUgarte, MD Department of Obstetrics and Gynecology CMD Fertility, Director Hadassah Hebrew-University Medical Center Assistant Clinical Volunteer Professor Jerusalem, Israel UCLA Department of OB/GYN Professor Contraception & Family Planning Los Angeles, California Embryology oft he Urogenital System & Congenital Kyle Bukowski, MD Abnormalities of the Genital Tract Health Sciences Oinical Instructor Department of Obsterics & Gynecology Oliver Dorigo, MD, PhD Univeristy of California Director and Associate Professor Los Angeles, California Division Gynecologic Oncology Perioperative, Intraoperative, & Department of Obstetrics and Gynecology Postoperative Complications in Stanford University Gynecologic Surgery; Therapeutic Stanford, California Gynecologic Procedures Premalignant & Malignant Disorders of the Uterine Corpus; Radiation & Chemotherapy for Gynecologic Cancers Ronald T. Burkman, MD Chair, Department of Obstetrics and Gynecology Michael P. Dougherty, MD Baystate Medical Center Department of Obstetrics and Gynecology Springfield, Massachusetts Rutgers Robert Wood Johnson Medical School Contraception & Family Planning New Brunswick, New Jersey Benign Disorders of the Uterine Corpus WendyY. Chang, MD, FACOG Scientific Director of Southern California Jennifer Duffy, MD Reproductive Center Fellow, Maternal Fetal Medicine Assistant Clinical Professor of Obstetrics & Department of Obstetrics and Gynecology Gynecology University of California, Irvine UCLA & USC Schools of Medicine Orange, California Beverly Hills, California Cardiac Disorders in Pregnancy Amenorrhea Samantha M. Dunham, MD Biing-JawChen, MD Oinical Assistant Professor Anesthesiologist NYU School of Medicine Torrance, California Obstetric Analgesia & Anesthesia NYU Langone Health New York, New York Early Pregnancy Risks Seth A. Cohen, MD Assistant Clinical Professor Margaret Dziadosz, MD Pelvic Medicine and Reconstructive Surgery New Jersey Perinatal Associates Division of Urology and Urologic Oncology RWJ Barnabas Health-Saint Barnabas Medical Center Department of Surgery, City of Hope Division of Maternal-Fetal Medicine Duarte, California Urinary Incontinence & Pelvic Floor Livingston, New Jersey Multifetal Gestation

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