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Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase PDF

12 Pages·2017·1.96 MB·English
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Preview Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase

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synthesize purines de novo and use the salvage pathway to synthesize purine bases, making this an attractive target for antiparasitic drug purine nucleotide on 5-phosphoribosyl-alpha-1-pyro- phosphate (PRPP). chromatic X-rays (λ = 1.537Å) and a MAR345 image plate as detector [18]. Two sets
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