Crossroads Between Innate and Adaptive Immunity IV PDF
Preview Crossroads Between Innate and Adaptive Immunity IV
Advances in Experimental Medicine and Biology 785 Peter D. Katsikis Stephen P. Schoenberger Bali Pulendran Editors Crossroads Between Innate and Adaptive Immunity IV Advances in Experimental Medicine and Biology Editorial Board: IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy For further volumes: http://www.springer.com/series/5584 Peter D. Katsikis (cid:129) Stephen P. Schoenberger Bali Pulendran Editors Crossroads Between Innate and Adaptive Immunity IV Editors Peter D. Katsikis Stephen P. Schoenberger Department of Microbiology Laboratory of Cellular Immunology and Immunology La Jolla Institute for Allergy College of Medicine and Immunology Drexel University La Jolla , CA, USA Philadelphia , PA, USA Bali Pulendran Emory Vaccine Center and Yerkes National Primate Research Center Emory University Atlanta , GA, USA ISSN 0065-2598 ISBN 978-1-4614-6216-3 ISBN 978-1-4614-6217-0 (eBook) DOI 10.1007/978-1-4614-6217-0 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2013932294 © Springer Science+Business Media New York 2013 This work is subject to copyright. 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Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com) Preface The reviews included in this volume are based on the work presented at the Aegean Conference “4th Crossroads between innate and adaptive immunity,” which occurred between September 11 and September 16, 2011, at the Royal Myconian Conference Center in Elia, Mykonos, Greece. This conference was the fourth in the series and brought together an international group of experts whose research focuses on the mechanisms by which innate and adaptive immunity is mounted in the host and the cellular and signaling pathways that lead to effective immunity. The conference included sessions dedicated to host recognition of and response to pathogens, innate immune responses, antigen presentation, and adaptive immunity. The goal of this conference was to foster scienti fi c exchange between these immunological fi elds, and promote discus- sion on the interactions between innate and adaptive immunity during host responses. The “4th Crossroads between Innate and Adaptive Immunity” Aegean Conference, with its highly interactive program, succeeded in bring- ing closely together scientists from around the world to discuss and establish collaborations in critical areas of innate and adaptive immunity. Philadelphia, PA, USA Peter D. Katsikis La Jolla, CA, USA Stephen P. Schoenberger Atlanta, GA, USA Bali Pulendran v Acknowledgements We would like to thank all the participants who attended the conference and shared their data and knowledge freely. This willingness to share new data, closely interact, and discuss is at the core of the Crossroads conferences and makes them the wonderful scientifi c experience they are. We especially would like to thank those who contributed chapters to this book, and we greatly appre- ciate their efforts and dedication. We would like to thank the people at Springer for giving us their support and the opportunity to publish these proceedings in their Advances in Experimental Medicine and Biology book series, with spe- cial thanks to Jacob Gallay for assembling and formatting the chapters. We would also like to thank the Aegean Conferences Organization for making the meeting possible and especially Dimitrios Lambris for his superb efforts in bringing the many organizational aspects of the Conference seamlessly together. Finally we would like to acknowledge the generous support from Aegean Conferences, eBioscience, P fi zer, Kirin, Springer, The Institute for Molecular Medicine and Infectious Disease at Drexel University College of Medicine, and Nature Immunology, without their support this meeting would not have been possible. Thank you all and we hope to see you all again in 2013! Philadelphia, PA, USA Peter D. Katsikis La jolla, CA, USA Stephen P. Schoenberger Atlanta, GA, USA Bali Pulendran vii Contents 1 Vita-PAMPs: Signatures of Microbial Viability ......................... 1 Diego Mourao-Sa, Soumit Roy, and J. Magarian Blander 2 Innate Lymphoid Cells in Immunity and Disease ...................... 9 You Yi Hwang and Andrew N.J. McKenzie 3 Tuning Cross-Presentation of Apoptotic T Cells in Immunopathology ..................................................................... 27 Vincenzo Barnaba 4 Regulation of Type 2 Immunity by Basophils ............................ 37 David Voehringer 5 Crosstalk Between Adaptive and Innate Immune Cells Leads to High Quality Immune Protection at the Mucosal Borders ................................................................. 43 Hilde Cheroutre and Yujun Huang 6 The Interaction Between Filarial Parasites and Human Monocyte/Macrophage Populations ...................... 49 Roshanak Tolouei Semnani 7 Innate-Like B Cells and Their Rules of Engagement ................ 57 Nicole Baumgarth 8 The CD28/B7 Pathway: A Novel Regulator of Plasma Cell Function ................................................................ 67 Modesta N. Njau and Joshy Jacob 9 Memory CD8+ T Cell Protection .................................................. 77 Sanda Remakus and Luis J. Sigal 10 Human T Follicular Helper Cells: Development and Subsets ............................................................. 87 Nathalie Schmitt and Hideki Ueno 11 Differentiation and Activation of gd T Lymphocytes: Focus on CD27 and CD28 Costimulatory Receptors ................. 95 Julie C. Ribot and Bruno Silva-Santos ix
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