CCOOSS--JJAAMM AAbbssttrraaccttss COLLEGE OF SCIENCE J OINT ANNUAL MEETING FFRRIIDDAAYY,, MMAAYY 33,, 22001133 Jordan Hall of Science | 1:00 – 5:00 p.m. ORAL PRESENTATIONS I // 1:00–2:30 p.m. Biological Sciences | Room 105 Chemistry & Biochemistry | Room 101 Mathematics | Room 310 Physics | Room 322 POSTER PRESENTATIONS & REFRESHMENTS 2:30–3:30 p.m. | Galleria ORAL PRESENTATIONS II // 3:30–5:00 p.m. Biological Sciences | Room 105 Chemistry & Biochemistry | Room 101 Mathematics | Room 310 Physics | Room 322 The College of Science Joint Annual Meeting is part of the 6th annual University of Notre Dame Undergraduate Scholars Conference. The intent of the Undergraduate Scholars Conference is to highlight the research achievements of all undergraduates to the Notre Dame community, including students, staff, and faculty. COLLEGE OF SCIENCE - JOINT ANNUAL MEETING Schedule and Abstracts Table of Contents Page Schedule 2 Biological Sciences 2 Chemistry and Biochemistry 7 Mathematics 9 Physics 10 Special Session Spirit of Science Award Winners 12 Abstracts 13 Index 167 Schedule - Biological Sciences Oral Presentations I Jordan Room 105 1:00 - 2:30 p.m. Moderator: Chilinh Nguyen 1:00 Gary Lamberti, Chair, Dept of Biological Sciences - Opening remarks 1:00 Erin Boyle - A Sensitized Screen for Genes that Interact with Bag-of-marbles During Definitive Hematopoiesis 1:15 Erin Flattery - Oxidative stress and drug resistance in the malaria parasite, Plasmodium falciparum 1:30 Stephanie Maciuba and Michelle Yanik - The Effects of Hydropropyl-β-Cyclodextrin on Organ Histology of Niemann-Pick Type C Mice 1:45 Andrew Mancini and Robert Kane - Knocking your SOX9 (and collagen and aggrecan) off: The Link Between Cortisol Levels and Osteoarthritis 2:00 Patrick O'Hayer - TNFRSFa is required for Müller glial proliferation in the light-damaged zebrafish (Danio rerio) retina 2:15 Michael Petravick - The Role of Sox2 in the Regenerating Zebrafish Retina Poster Presentations Jordan Galleria 2:30 - 3:30 p.m. Nestor Agbayani - Variations in the Erythrocytic Cycle Duration and Synchronicity of Plasmodium falciparum Patricia Amorado - The Toxicity of imidazolium ionic liquids on Chlamydomonas reinhardtii and Escherichia coli Nicholas Anderson - Predicting the effectiveness of chemical defenses based on the physical defenses of three gastropods in the presence of two crayfish predators Nathaniel Balmert - Time-of-day specific changes in metabolic detoxification and insecticide resistance in the malaria vector Anopheles gambiae Heather Boldt, Carolyn Hutyra, and Julia McGinty - Interactions between macrophages and exosomes containing mycobacterial components Elena Brindley - Characterizing the Protein-Protein Interactions of XAB2 and PPIE Both In and Outside of the Spliceosome Elena Brindley, Nicholas Deason, Katherine Hayman, Quynh Trang Hoang, and Jefferson Yu - Effects of Rhodopsin Impairment on Key Mosquito Behaviors Alexandria Brumfield - STARD9 is a novel transmembrane kinesin implicated in the dynamics of lysosomal membranes containing NPC1 and cholesterol Sarah Burbank - Influence of nutrient subsidies by spawning Pacific salmon (Oncorhynchus spp.) on riparian soils in southeast Alaska Lauren Callahan - Ribosome Exit Tunnel Site-Directed Mutagenesis 1 Kaylee Calles, Megan Ellis, Neil Sielski, Patrick Walsh, and John Werner - Regulation of Anoikis Inhibition in Prostate Cancer Margaret Davis - Genetic population structure in long-tailed macaques (Macaca fascicularis) in Bali, Indonesia Martha Dee - Nutrient limitation of riverine biofilms: the role of turbidity and cation-induced inhibition Kelly Deweese, Danielle Guilfoyle, and Tylor Gauger - Comparison of parasite infection in two populations of wild African elephants Jonathan Dowd and Joshua Junge - Characterization of Lactobacillus rhamnosis bacteriocin(s) Lauren Drapalik - The design and characterization of the SLS-ErbB2 immunotoxin Chiamaka Esomonu - Whole Brain-Whole Genome Analysis of the Alzheimer’s Disease Neuroimaging Initiative Amy Fernow - Laying the groundwork for association mapping in Black Walnut (Juglans nigra L.) Kelsey Flood - Understanding postglacial colonization of American beech through modern genetic structure Benjamin Foster - 5 Years of Germination Experiments on Schoenoplectus americanus Marissa Guo, Mark Brahier and Janel Allison - EPAC1 activation by 8-cpt-2-o-methyl-cAMP may reduce cholesterol accumulation in IB3-1 cells Chelsea Gyure - The Effects of Varying Cache Depth and Mammalian Predator Scent on the Foraging Behavior of the Forest Deer Mouse Jonathan Hancher - Classification of Periventricular White Matter Disease (WMD) in Clinical Radiology Reports vs. Direct Film Review in Ischemic Stroke Patients Jeffrey Hansen - The Effect of Baboon Hybridity on Parasite Resistance Mechanisms Justin Hansen, John Ning, and Anthony Sanchez - The miR-23a miRNA Cluster Forms a Gene Regulatory Loop with B cell Transcription Factors in Hematopoietic Cells Brendan Heiden - Ras activated MAPK signaling mediates metabolic rescue in extracellular matrix detachment Joel Hlavaty, Meghan Eastman, Andrew Mancini, Erin Franks, Jeremiah Scott, Joseph Scollan, and Kevin McAbee - May the force be with you: Dietary Seasonality and Adaptive Plasticity in Mammals Gwendolyn Hooley - Characterization of the MMAR_1663/1664 mutation in Mycobacterium marinum Liam Jackson - Determining the Role of Ubiquitination in Mycobacterial Component Trafficking Jonathan Jou, Gary Gerlach, and Robert McKee- Tight junction components are differentially expressed during zebrafish kidney development Jonathan Jou, Emma Collis, Daniel Ekeroth, Kyle Kimler, Rachel Miceli and Michael Petravick - Characterization of Fgf signaling during zebrafish kidney regeneration Nicholas Kalejs - The Effects of Biotic and Abiotic Factors on Lithobates sylvaticus Tadpole Body Mass Michael Kipp - Anisometropia and Amblyopia in Nasolacrimal Duct Obstruction Carson Kirkpatrick, Stephanie Bradburn and Kirk Mecklenburg - Evaluation of Aedes aegypti Opsin 1 Gene Promoter to Target Expression in Photoreceptor Cells 2 Caroline Ko - Retinophilin Control of NINAC Movements in Drosophila Photoreceptor Julia Kohn - Genetic population structure in long-tailed macaques (Macaca fascicularis) across Singapore Michael Kraft - Plants and mosquitoes: What do we need to know and why? John Kwon - Overlapping Roles for p31comet and Dynein in Silencing the Spindle Assembly Checkpoint John Lee - Sulfhydration and its Role in the Translocation of Protein Kinase Cε Samuel Lee - Molecular form- and sex-specific differences in locomotor/flight activity and the circadian clock of Anopheles gambiae mosquitoes Katherine Lenkiewicz - Temporal patterns of genetic variation at a site of introduction in the disease vector Aedes japonicus japonicus Jennifer Lesko and Andrew Marlin - Predicting Tree Mortality in a Northern Hardwood Forest David Link - Spatial and Temporal Variation in the Composition of Protozoan Parasites in Singapore Macaques Benjamin Luft - hsCRP predicts earlier time to mood episode in a Longitudinal Assessment of Manic Symptoms (LAMS-2) study cohort Miranda Madrid - Exploring the effects of host plant phenology and climate on the voltinism of two hybridizing species, Papilio glaucus and Papilio canadensis, using an individual-based simulation model Rebecca Marton - Interkinetic Nuclear Migration in the Regenerating Zebrafish Retina Claire Mattison and William Chronister - Effects of Precipitation on the Prairie-Forest Boundary in Illinois and Indiana Frank Mezzacappa - Ecdysone-induced protein 78C function in plasmatocyte survival and crystal cell fate commitment Matthew Mikulski, Matthew Schirtzinger, and Mackenzie Snead - A methodological comparison for stable carbon and nitrogen isotope analysis and applications to diet reconstruction Jacklyn Moon - The Effects of Taurine on Rod Photoreceptor Generation During Development Young Moon - Opsin maturation in Anopheles gambiae photoreceptors Michael Moore - Starvation and temperature has minimal effects on the isotopic fractionation in several crayfish tissues Janet Mostrom - Progress Towards the Development of an Assessment of Cell-Mediated Immune Response to an Attenuated FHV-1 Vaccine Vector Michelle Mueller and Zoe Volenec - Forest Composition Shifts in the Chicago Region from the Early 1800s to Today Zachary Osterholz - Evaluation of the accuracy of the BLM Alaska Lightning Detection System Nicholas Pagani - Ras mediated regulation of caspase-3 activity in extracellular matrix detachment Kevin Park - Comparison of species distribution modeling to biological factors in grass carp (Ctenopharyngodon idella) Riley Parrott - The lower lethal temperature of the eggs of the Karner blue butterfly (Lycaeides melissa samuelis) Andjela Pehar - Gene expression changes downstream of APC loss predict tumor phenotype 3 Iris Petersen - Infection with a trematode parasite (Microphallus spp.) increases aggression in native and invasive orconectid crayfish Jessica Puricelli - Effects of Streptococcus pyogenes Peptide Toxin Streptolysin S (SLS) on Apoptotic Signaling in Human Epithelial A-431 Cells Cameron Pywell - Ablation of the Id2 gene results in sex-specific circadian clock and metabolic phenotypes Manuel Rocha - Aedes aegypti Larval Photoreceptors Exhibit Patterned Expression of Rhodopsins Matthew Sarna - Identification of Surface-dependent Regulators of Swarm Motility in Pseudomonas aeruginosa Jonathan Savakus - Modulation of STAT3 Inhibitor Cytotoxicity by Multidrug Resistance Protein Inhibitors in in vitro Glioma Models Mary Schreck - Phytochemicals as Possible Mosquito Attractants in the Reduction of Mosquito- Borne Diseases Dayna Smith - Heavy Metal Contamination in Lake Michigan Wetland Turtles Michael Spear - Species distribution modeling of Trachemys scripta elegans in the Great Lakes region under current and future climate scenarios Suzanne Spitzer - A Hierarchy of Health: Dominance Rank and Parasite Burden in Wild Male Baboons Kristin Springer - Delineation of the role for Notch signaling during zebrafish kidney regeneration Mark Stechschulte - My, What Big Jaws You Have: Feeding Behavior and Mandibular Function in Feliformia Gwyneth Sullivan - Exploiting differences in Culex oviposition behavior for disease management Joshua Underhill - Fitness Changes of Daphnia pulex in Response to Thermal Stress Kaitlin VanderKolk - Characterization of a novel Leishmania aminopeptidase implicated in parasite virulence Tracy VandeWater - Exploring the “citizen science landscape” across the United States: assessing the field-to-date and identifying potential gaps Valerie Verdun - Analysis of Renal Progenitor Patterning During Zebrafish Kidney Development Tyler Wagner - Has an allele putatively involved in adaptation to climate in a butterfly hybrid zone shifted in response to recent warming? Ivy Yen - Effects of Daphnia puplex microbiome on stress response and survivorship Sue Yi - Exploring Biomarkers of Niemann-Pick Type C 4 Oral Presentations II Jordan Room 105 3:30 - 5:00 p.m. Moderator: Erin Boyle 3:30 Marilia Bianco de Moraes Figueiredo - Genetic differences over time can affect predictions in plant response to increased CO levels. 2 3:45 Erin Bouquet - Salt marsh plant exhibits phenotypic differences across space and time 4:00 Courtney Currier - Looking beyond macronutrients: Pacific salmon (Oncorhynchus spp.) as potential vectors of micronutrients to stream ecosystems 4:15 Whitney Preisser - The Relationship between Parasitic Nematode Infections and Body Condition in Wild Savannah Baboons (Papio cynocephalus) 4:30 Emily Spulak - The Influence of Sex and Age on Patterns of Parasitism in Wild Baboons 4:45 Daniel Williams - The Changing Forests of Ohio: Drivers of Composition Shifts Between the Settlement Era and Today 5 Schedule - Chemistry and Biochemistry Oral Presentations I Jordan Room 101 1:00 - 2:30 p.m. Moderator: Steven Wietstock 1:00 Michael Benvenuti - Paper Analytical Device lanes depend on multipart reagents and cool, dry storage for stability 1:15 Michelle Lundholm - Asymmetric Ketone Hydrogenation by Ruthenium Diphosphine Diamine Catalysts: A Computational Study 1:30 Timothy MacKenzie - Reaction Development: C-H Activation and Reactions of Cyclopentene Derivatives 1:45 Andrea Palazzolo - BTZ Scaffold Simplification: Combating Resistant Strains of Mycobacterium Tuberculosis 2:00 Ansel Nalin - Synthesis of Diospongins A, B, and C 2:15 Carolyn Keefe - S-block catalysts for copolymerization of CO[~2~] and epoxide Poster Presentations Jordan Galleria 2:30 - 3:30 p.m. Megan Fabry and Matthew Messana - Regulation of the oncogene ZNF217 by cellular localization during breast cancer progression Tiffany Fan - Synthesis of Sulfonamides and Amidines via Organophosphorus Activation Nathan Foje and Connor Wathen – In vivo Imaging of Soft Tissue Using Micro-X-Ray Computed Tomography With Injectable or Ingestible Contrast Agents Melissa Kander - Time-Resolved Resonance Raman Spectroscopy of Benzoate Adducts: A Computational Study Maggie Kerper - The Role of Znf217 in Mammary Gland Development Daniel Kwasnieski - Toward Single Molecule Combined Raman ‚Äì Electrochemical Studies Sean McGee - Green Design of “In the Field” Test for Iodine Deficiency Patrick McIntyre - Computational Investigation of Pt(557) and Au(557) Surface Restructuring Matthew Metzinger - Developing a Mouse Model for Epithelial Ovarian Cancer and Obesity Studies Kevin Nguyen – U PO and U PO : Chiral Uranium Cage Clusters 22 3 28 3 Amanda Randolph - Non-Classical Redox Reactions of Tris(3,5-di-tert- butylcatecholato)molybdenum(VI) John Rieth - Synthesis of Zampanolide Analogues Thaameran Sarveswaran - Quantification of β-lactam antibiotics in paper analytical devices using ImageJ software analysis Anna Sliwinski - Synthesis of Alkyl PBDTTT and the Effects of Alkylation on Polymer Solar Cell Performance 6 Lucy Smith and Paul DiGiovanni - ZNF217 interacts with the tumorigenic isoform of pyruvate kinase PKM2 Tanya Watts - Identifying the Role of ITGA3 in HCT116 Cells Through iTRAQ MS/MS and Wound Healing Assays Oral Presentations II Jordan Room 101 3:30 - 5:00 p.m. Moderator: Steve Wiestock 3:30 Sean Liebscher - Synthesis and Oxidation of BiIII to BiV in Aminetriaryloxide and Saltren Complexes 3:45 Patrick Kramer - Fluorescent Molecular Shuttles: Squaraine Rotaxanes As Ratiometric Chloride Sensors 4:00 Javier Pineda - Inhibition of Rogue Enzymes in Cancer: Elucidating the Binding Modes of Potential Small Molecule Therapeutics 4:15 Rachael Palumbo - Star Polymer as a Theranostic Agent for Cancer 4:30 Christina Mezes - Purification and characterization of ligand binding domains of NMDA receptor subunits 4:45 Consuelo Garcia - Evolutionary Relationships between CLAMP1 and EB1 7 Schedule – Mathematics Oral Presentations I Jordan 310 1:00 - 2:30 p.m. Moderator: Sonja Mapes 1:00 Matthew Charnley - Forward and Inverse Problems: An Exploration of Differential Equations 1:30 Katherine Ritchey - Linear Error Correcting Codes 2:00 Mitchell Faulk - Equal Entries in Totally Positive Matrices Poster Presentation Jordan Galleria 2:30 - 3:30 p.m. Matthew Cole - Elliptic Pairs, Lists, and Cycles Daniel Irvine - ECH Capacities of a Non-Convex Domain Fernando SanJuan - Clustering Dynamics of the Myxococcus xanthus Bacteria Michael Vella - The influence of network motifs on network dynamics and bistability Oral Presentations II Jordan 310 3:30 - 5:00 p.m. Moderator: Sonja Mapes 3:30 Daniel Irvine - An Introduction to Knot Theory and Knot Invariants 4:00 Murphy Kate Montee - Ubercrossing Knots: Knot Projections with a Single Multi-Crossing 8
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