Description:Figure 3. IGF-1 signalling in the pilosebaceous follicle and related interaction with androgen metabolism, androgen-dependent FGF-FGFR2b-signalling, endocrine and nutritional impact on IGF-1 homeostasis. (MAPK=mitogen-activated protein kinase; PI3K=phosphoinositide-3-kinase) [Melnik et al.,