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Confidence sets for functions of variance components in a mixed linear model PDF

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CONFIDENCE SETS FOR FUNCTIONS OF VARIANCE COMPONENTS IN A MIXED LINEAR MODEL BY ROBERT M. BASKIN A DISSERTATION PRESENTED TO THE GRADUATE SCHOOL OF THE UNIVERSITY OF FLORIDA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY UNIVERSITY OF FLORIDA 1991 ACKNOWLEDGEMENTS I would like to express my sincere gratitude to Professor Malay Ghosh for being my advisor, for proposing the problem of this dissertation, and for guiding me to its conclusion. Words cannot express what he has given to me. I would like to thank Professors Ronald Randles, P. V. Rao, Andre Khuri and Joe Glover for serving on my committee. Their efforts are truly appreciated. I would like to thank Andrew Rosalsky, Myron Chang, Geoff Vining and Mark Yang for their special attention and kindness. I am indebted to Richard Scheaffer, Alan Agresti, Malay Ghosh, Ronald Randles, and John Saw for guiding me through the graduate program at the University of Florida. If it were not for Ronald Randles I would not be here. I am indebted to Mike Conlon, Art Smith, Phil Padgett and everyone who made the departmental computer system operate. If it were not for them the simulations would never have been completed. My special thanks go to Carol Rozear, Nancy Pipkin, Leslie Easom, Marilyn Saddler and Cindy Zimmerman for taking care of many of the details and technical aspects of my stay here. Last, but not least, I would like to thank my kind and loving wife whose patience has been unbounded. m TABLE OF CONTENTS Page ACKNOWLEDGEMENTS iH ABSTRACT vi CHAPTERS ONE INTRODUCTION 1 1.1 Literature Review 1 1.2 The Subject of This Dissertation 6 1.3 Matrix Notations 9 TWO GENERAL LINEAR MODEL WITH TWO VARIANCE H COMPONENTS 2.1 Introduction 11 2.2 Henderson Estimates of Variance 16 2.3 Multivariate Central Limit Theorem 19 2.4 Jackknife Estimates 31 THREE GENERAL LINEAR MODEL WITH SEVERAL VARIANCE COMPONENTS 81 3.1 Introduction 81 3.2 Multivariate Central Limit Theorem 83 3.3 Jackknife Estimates 95 FOUR HIERARCHICAL BAYES ESTIMATION OF THE VARIANCE RATIO 123 4.1 Introduction 123 4.2 The Derivation of the Bayes Estimator 125 4.3 Jackknifed Estimator of the Asymptotic Variance 135 FIVE RESULTS OF SIMULATIONS 144 5.1 Introduction 144 5.2 The Simulation Results for the Unbalanced Model 144 5.3 The Simulation Results for the Balanced Model 148 IV SIX SUMMARY AND FUTURE RESEARCH . 155 6.1 Summary 155 6.2 Future Research 156 BIBLIOGRAPHY 157 BIOGRAPHICAL SKETCH 161 v Abstract of Dissertation Presented to the Graduate School of the University of Florida in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy CONFIDENCE SETS FOR FUNCTIONS OF VARIANCE COMPONENTS IN A MIXED LINEAR MODEL By Robert M. Baskin August, 1991 Chairman: Dr. Malay Ghosh Major Department: Statistics In this dissertation a distribution-free approach to construction of confidence sets is employed by using resampling techniques in a general linear model including covariates. Initially only models with two variance components are explored since this gives rise to the common situation of estimating the ’’heritability ratio.” Some of the widely used models in small area estimation including the nested error regression model, random regression coefficients model, etc. considered by earlier authors are seen to be special cases of this model. The asymptotic properties of the jackknifed versions of the Henderson III estimators as well as the jackknifed estimates of variance are studied. This is extended to models with several random components but still including covariates. In the situation of a balanced one-way Anova model with covariates a hierarchical Bayes estimator of the variance ratio is derived. The asymptotic distribution of this estimator is derived under a frequentist model. vi The jackknife estimate of variance for this estimator is shown to be consistent and used to construct confidence sets for the variance ratio. Finally computer simulations of some of these models are used to illustrate the features of the work. vi1 CHAPTER ONE INTRODUCTION 1.1 Literature Review While the employment of linear models can be traced back for centuries in specific fields such as astronomy, where they have been used for predicting the position of celestial bodies, the latter half of this century has seen linear models rise to be a standard method in many other fields, especially such fields as genetic selection, psychometrics, and survey sampling. Indeed, breeders of both plants and animals have used variance components in linear models extensively for predicting characteristics of future progeny since the landmark works of Henderson (1950,1953). For purposes of selecting the most desirable trait of progeny under consideration, breeders produce what is referred to as a selection index based on certain linear combinations of fixed and random components under a mixed linear model. Discussion of selection indices in plant breeding may be found in Henderson (1963) while a discussion of these indices in dairy cattle breeding may be found in Lush and Shrode (1950) or Henderson, Kempthorne, Searle, and von Krosigh (1959). Other references in this area are cited in Gianola and Fernando (1986) and Harville (1990). The fields of education and psychometrics have made varied use of 1 . 2 linear models for measurement purposes. Further references are given in Algina and Crocker (1986). In survey sampling, survey analysts have used linear models in finite population sampling to predict characteristics of the unsampled units based on the observed sample. One of the first recognized uses of linear models in general, and variance components in particular, in the area of survey sampling is due to Cochran (1939). Because of limited resources as well as rapid development of sophisticated statistical techniques by such pioneers as Cochran, sample surveys have been widely used in this country for over half a century. These surveys have provided reliable statistics on the national and state level with growing regularity and with the advent of electronic telecommunications equipment have increased in both frequency and application. However, in the past, the use of these methods in sublevels below the state level has been limited because the estimates for these sublevels have usually been based on small sample sizes, at least within the sublevels, and thus these estimates produced unacceptably large standard errors. Therefore, little of the early work of survey analysts was devoted to producing reliable small area estimators In recent years, however, small area estimation has grown into an important topic in survey sampling. Many government agencies such as the United States Census Bureau, Statistics Canada, and the Central Bureau of Statistics of Norway have been involved in estimating population counts, unemployment rates, per capita income, etc. for 3 sublevels below the state, province, or fylker level. In this light, small area estimation techniques have been devised that ’’borrow strength” from similar neighboring areas for estimation and prediction purposes. A good review of small area estimators may be found in Ghosh and Rao (1991). This review shows how linear model techniques can be used to address small area estimation problems. In determining the effectiveness of the Henderson method of estimating the variance components in a linear mixed model statisticians have proposed certain minimal properties for a desirable estimator. In an early paper by Yates and Zacopancy (1935) an example is given showing the possibility of producing a negative estimate of variance by a standard Anova estimate. With few exceptions (see for example Smith and Murray (1984)) this particular facet of the problem has always been a drawback from the point of view of most statisticians. Typically the solution to this problem is to use the positive part of the variance estimator as in Crump (1951) or Snedecor and Cochran (1967). As shown by Pukelsheim (1977,1981) and discussed further by Rao and Kleffe (1988) the situations in which linear combinations of the effects in a linear model are nonnegatively estimable are rare. In a comparison of several variance estimators Corbeil and Searle (1976) point out that maximum likelihood estimators of variance components require that the likelihood function be maximized over the positive space of the variance component parameters. In an extensive work Harville (1977) reviews much of the material on standard Anova

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