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Clinics in Laboratory Medicine 1992: Vol 12 Index PDF

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CUMULATIVE INDEX 1992 Volume 12 March LABORATORY IMMUNOLOGY I, pages 1-162 June LABORATORY IMMUNOLOGY II, pages 163-392 September REPRODUCTIVE MEDICINE AND THE CLINICAL LABORATORY, 393-654 ‘December SELECTED TOPICS IN TRANSFUSION MEDICINE, pages 655. 826 Note: Page numbers of article titles are in boldface type ABO blood groups, determination of, for Alanyl tRNA synthetase, antibodies to, in transfusion, 686-689 polymyositis, 11 hemolytic disease of newborn and, 556- Albumin, fetal. See Alpha-fetoprotein. 559 in hemapheresis, 591, 593, 598-599 in parentage analysis, 621-625 Allele-specific oligonucleotide probes, in Abortion, immunologic mechanisms in, Tay-Sachs disease assessment, 472 557, 559 Alloantibody analysis, in hemolytic Accident reports, in transfusion medicine, disease of newborn, 561-562 837 Allograft rejection. See Transplantation, Acetylcholinesterase, measurement of, rejection markers in. neural tube defects and, 485, 489 Alloimmunization, to human leukocyte Acid-base status, fetal, assessment of, antigens, prevention of, in 517-518 transfusion, 711-713 Acidosis, in hemolytic disease of to platelet antigens, neonatal thrombo- newborn, 564 cytopenia in, 577-586 Acrosome reaction, of sperm, 414-415 to red cells. See Hemolytic disease of new- Actin-cytoskeleton, integrin interaction born. with, 223-224 Allophycocyanin, in flow cytometry, 246 Acute lymphoblastic leukemia, minimal Alpha-fetoprotein, isoforms of, 482 residual cells from, detection of, 139- levels of, in disease, 482-483 145 measurement of, 481-492 Acute myelogenous leukemia, minimal clinical uses of, 483-484 residual cells from, detection of, 145 diabetes mellitus and, 487 Adenosine deaminase deficiency, prenatal drug ingestion and, 487-488 diagnosis of, 513 gestational age and, 486 Adhesion, cellular, integrins in. See _ in amniotic fluid, 488 Integrins. materials for, 484 Adsorption filtration, of transfusion maternal weight and, 486-487 components, for microbial removal, methods for, 484—485 791-792 multiple of median value in, 485-486 Adult T-cell lymphoma-leukemia multiple pregnancy and, 487 syndrome, flow cytometric analysis racial factors in, 487 in, 262 results handling in, 485-489 862 CUMULATIVE INDEX 1992 Alpha-fetoprotein (Continued) Antibody-dependent cell-mediated assay, physicochemicai properties of, 481 in hemolytic disease of newborn, 562 American Association of Blood Banks, Antibody-dependent cellular cytotoxicity, legal issues in transfusion and, 819, in HIV infection, 317 822, 825-826, 831 Anticardiolipin antibodies, familial, 43 Aminomethyl trimethyl psoralen in neurologic disease, 75 treatment, of transfusion in recurrent spontaneous miscarriage, components, 796 407 Amniocentesis, alpha-fetoprotein testing incidence of, 42-43 and, 484, 488-489 Anticoagulant(s), in antiphospholipid in fetal lung maturity assessment, 603- antibody syndrome, 46-47 630 lupus. See Lupus anticoagulant. in granulomatous disease detection, 298 Antifibrinolytic agents, in hemostasis, 776 in prenatal diagnosis, 494-495 Antigens. See also specific antigen, e.g., efficacy of, 500 p24 antigen. hemolytic disease of newborn, 559- alloimmunization to, prevention of, in 561 transfusion, 711-713 Tay-Sachs disease, 469 phenotyping of, 765 toxoplasmosis, 508 in HIV infection, 308, 310, 317-318 Amniotic fluid, surfactant in, 606-607 in rheumatic disease, autoantibodies to. Amplified fragment length See under Autoantibodies. polymorphisms, in parentage platelet. See Platelet antigens. analysis, 633 red blood cell. See Blood group markers. Androgens, assessment of, in infertility to proliferating cells, in cell cycle analy- evaluation, 398 sis, 179, 190-192 in hemostasis, 776 Antiglobulin test, in antibody screening, Anemia, aplastic, diagnosis of, molecular 690-692 probe techniques in, 115 in crossmatching, 692-694 hemolytic, in antiphospholipid antibody Antimitochondrial antibodies, in chronic syndrome, 45 active hepatitis, 33 in newborn. See Hemolytic disease of in primary biliary cirrhosis, 35-36 newborn. Antineutrophil cytoplasmic transfusion in, 655-656 autoantibodies, 85-98 alternatives to, 658 C-pattern, 85-87 hemoglobin level trigger point and, Wegener's granulomatosis and, 87, 89 656-658 circulating, 92, 94 Angelman syndrome, prenatal diagnosis conditions associated with, 92 of, 498 detection of, 86-87 Antepartum nonstress test, in hemolytic elastase type, 91-92 disease of newborn, 563 historical aspects of, 85-86 Anti-immunoglobulin G reagent, in in primary sclerosing cholangitis, 37-38 antibody screening, for transfusion, in Wegener's granulomatosis, 87, 89 690 lactoferrin type, 91-92 Antibiotic treatment, of transfusion myeloperoxidase recognition by, 85-87, components, 793-794 89-91, 94 Antibodies. See also Autoantibodies; P (perinuclear/nuclear staining)-pattern, specific antibody, e.g., 86, 92 Antiphospholipid antibodies. pathogenicity of, 92, 94 antiphospholipid, in recurrent sponta- sensitivity of, 91 neous miscarriage, 407 specificity of, 91 antisperm, detection of, 399-400, 402 Antinuclear antibodies, detection methods in drug-induced lupus erythematosus, for, 15-16 8-9 in chronic active hepatitis, 26, 29 monoclonal. See Monoclonal antibodies. in recurrent spontaneous miscarriage, platelet, in transfusion, 663 407 testing for, in transfusion, 687-688, in rheumatic disease, 2 690-692 tests for, 7 to HIV. See under Human immunodefi- Antiphospholipid antibodies, animal ciency virus. models for, 48 CUMULATIVE INDEX 1992 avidity of, 49 polymyositis, 11-12 binding to phospholipids, 49-50 rheumatoid arthritis, 13-15 characteristics of, 48-51 scleroderma, 12-13 cofactors for, 50-51 Sjégren’s syndrome, 10-11 familial associations of, 43 systemic lupus erythematosus, 2-8, in neurologic disease, 75-76 76, 90 in recurrent spontaneous miscarriage, to Me autoantigen, 17-18 407 to nuclear lamins, 16-17 incidence of, 42-43 to poly (ADP-ribose) polymerase, 17 isotypes of, 49 in Wegener's granulomatosis, 87, 89 pathogenicity of, 51-52 to neutrophils, 91-92 specificity of, 49-50 Autoimmune disease, antiphospholipid Antiphospholipid antibody syndrome, 41- antibody syndrome, 41-60 60 of liver, 25-40 historical background of, 41-42 chronic active hepatitis, 26-34 primary, clinical manifestations of, 43- primary biliary cirrhosis, 34-37 46 primary sclerosing cholangitis, 37-38 treatment of, 46-48 Autoimmune disorders, in blood donors, Antiribossomal P protein, antibodies to, guidelines for, 678 lupus psychosis and, 76 Autoimmune thrombocytopenia, platelet Antisperm antibodies, detection of, 399- transfusion in, 660-661 400, 402 Autologous transfusion. See under Antithrombin III, transfusion of, 751-753 Transfusion. Antiviral drug treatment, of transfusion Automated reagin test, for syphilis, 529 components, 793-794 Automation, in laboratory testing, 851- Apheresis, components from, uses of, 852 774-775 Autoradiography, in cell cycle analysis, donor screening for, 681 172-173 platelets from, 663, 774-775 Avitene, in hemostasis, 777 techniques for, 774-775 Azathioprine, in chronic active hepatitis, Aplastic anemia, diagnosis of, molecular 34 probe techniques in, 115 Aprotinin, in hemostasis, 776-777 Artificial insemination, ethical and lega! considerations in, 430-436 B-cell lymphoproliferative disorders, after Autoantibodies. See also specific bone marrow transplantation, antibody, e.g., Antinuclear antibodies. detection of, 123-124 in chronic active hepatitis, 26-27, 29-33 B-cell prolymphocytic leukemia, flow in CREST syndrome, 12-13 cytometric analysis in, 260 in Eaton-Lambert syndrome, 77-78 Babesia, in blood transfusion components, in neurologic disease, 61-83 donor screening for, 676 to antiribossomal P protein, 76 inactivation of, 788 to calcium channel, 77-78 Bacteria, in blood transfusion to Ki antigen, 77 components, inactivation of. See to neurofilament, 77 Microbial inactivation. to neuronal ganglioside antigens, 64— testing for, 763 75 Bak antigens, in neonatal alloimmune to neuronal proteins, 62-64 thrombocytopenia, 581 to phospholipids, 75-76 Basal body temperature, in ovulation in primary biliary cirrhosis, 35-36 documentation, 393-395 in primary sclerosing cholangitis, 37-38 Bayes theorem, in paternity inclusion in rheumatic disease, 1-23 calculation, 629 biological functions of, 18-19 Beckwith-Wiedemann syndrome, prenatal dermatomyositis, 11-12 diagnosis of, 499 detection methods for, 15-16 Benzoporphyrin derivative treatment, of drug-induced lupus erythematosus, transfusion components, 797 8-9 Bernard-Soulier syndrome, neonatal mixed connective tissue disease, 9-10 alloimmune thrombocytopenia and, of rare occurrence, 16-17 581 864 CUMULATIVE INDEX 1992 Beta-hexosaminidase A deficiency, in Tay- chronic myelogenous leukemia, 133- Sachs disease, 465, 467-470 139 Beta-propriolactone treatment, of hybridization assay in, 130-131, 137 transfusion components, 795 immunoglobulin rearrangements, 144 Biliary cirrhosis, primary, 34-37 immunophenotyping in, 130 Bilirubin, in amniotic fluid, in hemolytic in autologous marrow, 115-116, 146 disease of newborn, 559-561 lymphoma, 146 Biohazardous waste disposal, regulations polymerase chain reaction in, 131- on, 841 133, 135-145 Blastomycosis, prenatal diagnosis of, 544— Southern blot in, 130, 135 545 T-cell receptor rearrangements, 144- Blood, fetal, disorders of, diagnosis of, 145 512-517 molecular probe techniques in, 113-128 sampling of, 495. See also Cordocen- for engraftment documentation, 119- tesis. 121 lysis of, for flow cytometry, 266-268 for hemopoietic reconstitution clonal- shipment of, regulations on, 841 ity determination, 121-122 storage of, before transfusion, 706 for histocompatibility typing, 116-119 transfusion of. See Transfusion. for immunodeficiency evaluation, 122 Blood banks, liability of. See Legal issues, for infection diagnosis, 122-123 in transfusion medicine. for pretransplant disease identifica- regulation of. See Regulatory and legisla- tion, 114-116 tive issues, in transfusion medicine. for secondary malignancies detection, Blood-borne Pathogen Standard, 840-841 123-124 Blood components, transfusion of. See minisatellite type, 120 Transfusion. Borreliosis, prenatal diagnosis of, 524-525 Blood donors, safety for, 678-680 Bovine cervical mucus penetration test, screening of, 669-683 403 confidential unit exclusion and, 673- Br antigens, in neonatal alloimmune 675, 703 thrombocytopenia, 581 donor education in, 670-671 Breast cancer, paraneoplastic syndrome for apheresis, 681 in, autoantibodies in, 63-64 for donor safety, 678-680 Bromodeoxyuridine incorporation for infectious diseases, 675-676, 701- method, in cell cycle analysis, 179, 703 190 for red cell antibodies, 687-688 goals of, 669 in autologous donation, 680 in directed donation, 681 Calcium channels, antibodies to, in medical history in, 672-673, 677-678 neurologic disease, 77-78 medication use and, 677 Canadian Association of Pathologists, national donor referral registry and, workload recording method of, 339- 341 681-682 vaccination and, 676-677 Cancer, cell proliferation markers in. See Blood group markers, hemolytic disease Cell proliferation markers. of newborn and, 556-559 immunotherapy in, monoclonal anti- in linkage analysis, 454-455 bodies in. See under Monoclonal in parentage analysis, 621-625 antibodies. Blood protein polymorphisms, in in blood donors, guidelines for, 677-678 parentage analysis, 625-627 integrins role in, 220-222 Blood shield statutes, 820-821 paraneoplastic syndromes in, autoanti- Bone marrow transplantation, graft- bodies in, 62-64, 77-78 versus-host disease in, 749-751 recurrence of, from transfusion immu- minimal residual disease detection in, nosuppression, 717, 724-726 129-150, 764-765 secondary, in bone marrow transplanta- acute lymphoblastic leukemia, 139- tion, detection of, 123-124 143 Candidiasis, prenatal diagnosis of, 544 acute myelogenous leukemia, 145 Capacitation, of sperm, 413-414 CUMULATIVE INDEX 1992 865 Carcinogenesis, cell proliferation markers monoclonal antibody-drug conjugates and, 164-168 (chemoimmunoconjugates) in, 207- Carcinoma, in blood donors, guidelines 210 for, 678 Chicken pox, prenatal diagnosis of, 511 Cardiac disease, in antiphospholipid Chimerism, in bone marrow antibody syndrome, 46 transplantation, 119-121 cDNA sequencing, in granulomatous Chlamydial infections, diagnosis of, in disease, 297 infertility evaluation, 398-399, 402 Cell(s), adhesion of, integrins in. See in recurrent spontaneous miscarriage, Integrins. 405 differentiation of, integrins in, 222-223 prenatal, 538 fixation of, for flow cytometry, 273 Cholangitis, primary sclerosing, 37-38 labeling of, for flow cytometry, 269-273 Chorionic villus sampling, 494 signal transduction pathways of, inte- efficacy of, 500 grin interaction with, 224-226 in granulomatous disease detection, 298 Cell counters, in fetal lung maturity in hemolytic disease of newborn, 564 Chromatography, high-pressure liquid, assessment, 615-617 Cell cycle, cell proliferation markers and, for neopterin, 102-103 169-180 thin-layer, in antiganglioside antibody detection, 74 phases of, 169-171 in fetal lung maturity assessment, quantitative measurement of, 171-180 609-611 Cell proliferation antigens. See Proliferating cell antigens. Chromosomal analysis, in recurrent spontaneous miscarriage, 406 Cell proliferation markers, 163-199 prenatal, 497-499 carcinogenesis and, 164-168 cordocentesis in, 505-507 cell cycle and, 169-180 Chromosome jumping, in linkage clinical significance of, 180-192 analysis, 455 growth kinetics and, 168-169 Chromosome walking, in linkage analysis, measurement of, antigen analysis in, 455 190-192 Chronic inflammatory demyelinating flow cytometry in, 186-190 polyneuropathy, plasmapheresis in, halogenated pyrimidine incorporation 600 in, 190 Chronic lymphocytic leukemia, flow nuclear organizer region technique in, cytometric analysis in, 258, 260 192 Chronic myelogenous leukemia, minimal metastasis and, 166-168, 182-184 residual cells from, detection of, 133- prognostic implications of, 180-182, 139 186-190 Cirrhosis, primary biliary, 34-37 therapeutic implications of, 184-186 Clinical Laboratory Improvement tumor biology and, 164-169 Amendments of 1988, 839-840, 850- tumor heterogeneity and, 168 851 Centromere antigens, antibodies to, in Clonal deletion theory, of immunosup- scleroderma, 13 pression, in transfusion, 730 Cerebellar degeneration, paraneoplastic, Clonality, in bone marrow autoantibodies in, 62-63 transplantation, molecular probe Cerebrospinal fluid testing, in determination of, 121-122 coccidioidomycosis, 545 Clustering, in test selection, 363-370 Cervical mucus penetration test, 403 Coagulopathy, antithrombin III Chagas’ disease, transmission of, in replacement in, 751-753 transfusion, 763 cryoprecipitate transfusion in, 665, 772 blood donor screening for, 676 diagnosis of, 764-765 Chemical inactivation, of pathogens, in dilutional, plasma transfusion in, 663- transfusion components, 793 664 Chemiluminescence assay, monocyte- in massive transfusion, 745, 748 mediated, in hemolytic disease of plasma transfusion in, 664, 772-773 newborn, 562 prenatal diagnosis of, 512-513 Chemotherapy, cell proliferation markers preoperative evaluation of, transfusion in, 184-186 therapy and, 773-774 866 CUMULATIVE INDEX 1992 Coccidioidomycosis, prenatal diagnosis of, of embryo, in assisted reproduction, 545-546 421, 430-431 Collagen, microfibrillar, in hemostasis, Cryptococcosis, prenatal diagnosis of, 546 777 Culture, of Blastomyces dermatitidis, 544—- College of American Pathologists, 545 proficiency testing programs of, 850- of Borrelia burgdorferi, 524 851 of chlamydia, 538 workload recording method of. See of embryos, for in vitro fertilization, Workload recording method. 421-424 Combined immunodeficiency, prenatal of enteroviruses, 536 diagnosis of, 513-514 of herpes simplex virus, 535 Compatibility testing, in transfusion. See of HIV, 318-319, 533 Red cells, transfusion of, safety in. of Listeria monocytogenes, 526 Complement fixation test, in of microorganisms, in infertility evalua- coccidioidomycosis, 545 tion, 398-399 in toxoplasmosis, 541-542 of Mycobacterium tuberculosis, 527 in trypanosomiasis, 543 of Mycoplasma hominis, 529 Confidential unit exclusion, in blood of Neisseria gonorrhoeae, 528 donation, 673-675, 703 of rubella virus, 534 Congenital disease. See also Genetic of streptococci, 525-526 disease. of Ureaplasma urealyticum, 529 markers for, alpha-fetoprotein as, 481- of varicella-zoster virus, 536-537 492 Cystic fibrosis, linkage analysis in, 458- prenatal diagnosis of, cordocentesis in. 459 See Cordocentesis. Cytapheresis, in pregnancy, 593-594 Congenital varicella syndrome, 536 Cytochrome P-450 antibodies, in chronic Connective tissue disease, mixed, active hepatitis, 30-32 autoantibodies in, 9-10 Cytogenetics, prenatal, 496 Cordocentesis, 503-522 cordocentesis in, 505-507 complications of, 504-505 efficacy of, 500-501 diagnostic uses of, acid-base balance fetal cells in maternal blood, 496 evaluation, 517-518 in chromosomal abnormality detec- chromosomal analysis, 505-507 tion, 497-500 congenital infection identification, indications for, 496-497 507-512 sample collection for, 494-495 hematologic disorders, 512-517 Cytomegalovirus infection, prenatal hemolytic disease of newborn, 563- diagnosis of, 510, 531-532 564 transmission in transfusion, reduction metabolic status assessment, 517-518 of, 713-714, 763 historical review of, 503 to neonates, 747 methodology for, 503-504 viral inactivation and, 788 Corticosteroids, in chronic active Cytophilic antibody, in flow cytometry, of hepatitis, 34 lymphocyte markers, 262 Counseling, linkage analysis and, 458-460 Cytosolic components, autoantibodies Coupling, in linkage analysis, 450 against, in chronic active hepatitis, Coxsackievirus infections, prenatal 32-33 diagnosis of, 536 CREST syndrome, autoantibodies in, 12- 13 Creutzfeldt-Jakob disease, screening for, D antigens, determination of, for in blood donors, 676 transfusion, 686-687, 689 Crohn’s disease, transfusion in, Danazol, in hemostasis, 776 immunosuppression in, 727-728 Data collection, for test selection, 356 Crossmatching, in transfusion, 692-694 in workload recording method, 344-345 Cryoprecipitate, transfusion of, 665 Data organization, for test selection. See guidelines for, 772 Test selection. Cryopreservation, for flow cytometry, DDAVP (desmopressin), in hemostasis, 268-269 775 CUMULATIVE INDEX 1992 867 3-Deamino-3-(4-morpholinyl)- Doppler analysis, in hemolytic disease of doxorubicin-monoclonal antibody newborn, 563 conjugate, in cancer immunotherapy, Down syndrome, markers for, 489-490 208-209 Drug(s), alpha-fetoprotein results and, 1-Deamino-8D-arginine (DDAVP), in 487-488 hemostasis, 775 exclusion of, from donated blood, 677 Decision making, for test selection. See lupus erythematosus induced by, anti- Test selection. bodies in, 8-9 Dehydroepiandrosterone sulfate, monoclonal antibody-drug conjugates assessment of, in infertility with, 207-210 evaluation, 398 Duffy antigens, in hemolytic disease of Dendrograms, in test selection, 361 newborn, 557 Dermatomyositis, autoantibodies in, 11- in parentage analysis, 623 12 Dyes, DNA-specific, in cell cycle analysis, 4-Desacetylvinblastine-3- 173-179 carboxyhydrazide-monoclonal antibody conjugate, in cancer immunotherapy, 209-210 Desmopressin, in hemostasis, 775 Early antigen of Epstein-Barr virus, Detergent treatment, of transfusion antibodies to, in rheumatoid arthritis, components, 798 14 Diabetes mellitus, alpha-fetoprotein Eaton-Lambert syndrome, autoantibodies results and, 487 in, 77-78 DiGeorge syndrome, prenatal diagnosis Effector cells, in immunotherapy, of, 456, 498 activation of, 202-205 Direct antiglobulin test, in hemolytic redirection to tumor sites, 205-207 disease of newborn, 556 Elastase, antineutrophil cytoplasmic Direct sequencing, of DNA, in parentage autoantibodies to, 91-92 analysis, 634 Electrolytes, in embryo culture media, 423 Directed donation, of blood, transfusion Electron microscopy, pseudoreplica of, 681, 780 method of, in cytomegalovirus Disintegrins, 230 detection, 531 DNA, denatured, antibodies to, in drug- Electrophoresis, in hexosaminidase A induced lupus erythematosus, 8-9 detection, 468 halogenated pyrimidine incorporation in parentage analysis, 625-627 into, in cell cycle analysis, 179 ELISA. See Enzyme-linked immunosorbent identification of, in HIV, 319-320 assay. native, antibodies to, in SLE, 2-3 Embryo, development of, integrins in, nucleolar organizer regions of, in cell 222-223 proliferation measurement, 179- for assisted reproduction, cryopreserva- 180, 192 tion of, 430-431 quantitation in cell cycle analysis, 173- culture of, 421-424 180 ethical and legal status of, 441-445 clinical significance of, 180-192 handling of, 415-421 DNA hybridization, in bone marrow Encephalomyelitis, paraneoplastic, minimal residual disease, 130-131, autoantibodies in, 64 137 Endometrial biopsy, in infertility in HIV testing, 319-320 evaluation, 396-397 DNA index, in cell cycle analysis, 174-176 in recurrent spontaneous miscarriage, DNA ploidy. See Ploidy. 406-407 DNA probes, in malaria diagnosis, 542 Endometrial carcinoma stage I prognostic DNA-specific dyes, in cell cycle analysis, index, 189 173-179 Endothelial cells, antibodies to, 51-52 DNA studies, in parentage analysis, 630- integrins associated with, 219 636 Enterovirus infections, prenatal diagnosis DNA topoisomerase II, antibodies to, in of, 535-536 rheumatic disease, 17-18 Environmental Protection Agency, Donors, blood. See Blood donors. medical waste regulation by, 841 868 CUMULATIVE INDEX 1992 Enzyme analysis, in phosphatidylglycerol Ethical and legal considerations, in determination, 611 assisted reproduction, 429-448 in Tay-Sachs disease diagnosis, 469 exploitation and, 439-442 Enzyme immunoassay, for alpha- extrauterine embryo status, 442-445 fetoprotein, 484-485 nuclear family fate and, 432-439 for luteinizing hormone surge assess- in Tay-Sachs screening, 476-477 ment, 395 Ethidium bromide, in cell cycle analysis, in autoantibody detection, 15-16 174 in chlamydial infections, 538 Exclusion filtration, of transfusion in cryptococcosis, 546 components, for microbial removal, in gonorrhea, 528 791 in hepatitis B, 538 in HIV infection, 532 in streptococcal infections, 526 Enzyme-linked immunosorbent assay, for Factor VIII, transfusion of, 665 hormones, in infertility evaluation, Family law, in assisted reproduction. See 397 under Ethical and legal considerations. for infectious organisms, Borrelia burg- FDA (Food and Drug Administration), dorferi, 524 transfusion medicine regulation by, in infertility evaluation, 397 836-838 Listeria monocytogenes, 526 Fertilization, in vitro. See In vitro Toxoplasma gondii, 508, 540-541 fertilization. Treponema pallidum, 530 Fetus, alloimmune thrombocytopenia in antiganglioside antibody detection, deveiopment in, 577-586 73-74 alpha-fetoprotein levels in. See Alpha- in antineutrophil cytoplasmic autoanti- fetoprotein. body detection, 86-87 cells of, in maternal blood, 496 in autoantibody detection, 15-16 diagnosis of disorders in, blastomy- in HIV testing, 311-314, 317-318 cosis, 544—545 in interleukin—2 soluble receptor analy- blood disorders, 512-517. See also sis, 104 Hemolytic disease of newborn. Epidermal growth factor receptors, in blood sampling for, 495. See also Cor- tumor, monoclonal antibodies docentesis. directed to, 210-211 candidiasis, 544 Epithelial cells, integrins associated with, chlamydial infection, 538 218-220 coccidioidomycosis, 545-546 Epstein-Barr virus, detection of, after cryptococcosis, 546 bone marrow transplantation, 123 cytomegalovirus infection, 510, in blood transfusion components, 763 532 rheumatoid arthritis and, 14 enterovirus infections, 535-536 transmission in transfusion, reduction gonorrhea, 527-528 of, 714-715 hepatitis B, 537-538 Error reports, in transfusion medicine, 837 herpes simplex virus infection, 534- Erythema infectiosum (parvovirus B19 535 infection), in blood transfusion HIV infection, 532-533 components, testing for, 763 hydrops, 516-517 prenatal diagnosis of, 511-512, 537 infections, 523-552 Erythrocytes. See Red cells. listeriosis, 526-527 Erythroderma, postoperative, in graft- Lyme disease, 524-525 versus-host disease, 749 malaria, 542 Erythropoietin, as transfusion alternative, mycoplasmal infections, 528-529 658, 777-778 papillomavirus infection, 538-539 in *:emolytic disease of newborn, 564- parvovirus B19 infection, 511-512, 565 537 Estradiol, assessment of, in infertility rubella, 510-511, 533-534 evaluation, 398 streptococcal infections, 525-526 Estriol, unconjugated, in Down syndrome syphilis, 529-530 screening, 489-490 Tay-Sachs disease, 468-469 Estrogens, in hemostasis, 776 toxoplasmosis, 507-510, 539-542 CUMULATIVE INDEX 1992 869 trypanosomiasis, 543 in proliferating-cell antigen analysis, tuberculosis, 527 190-192 varicella-zoster virus infection, 511, Fluorescein, in flow cytometry, 245, 263- 536-537 264 lung maturity assessment in, 603-630 Fluorescence, depolarization of, in fetal parentage analysis of, 636 lung maturity assessment, 615-616 transfusion for, in alloimmune throm- Fluorescent treponemal antibody bocytopenia, 584 absorption test, for syphilis, 529-530 in hemolytic disease of newborn, Fluorochromes, in cell cycle analysis, 173- 566-568 179 Feulgen staining technique, in static in flow cytometry, of lymphocyte mark- cytophotometry, 178 ers, 245-246, 271-273 Fibrillarin, antibodies to, in scleroderma, Foam-stability assay, in fetal lung 13 maturity assessment, 614-615 Fibrin surgical adhesive, in hemostasis, Follicle-stimulating hormone, assessment 777 of, in infertility evaluation, 398, 402 Fibrinogen, integrin recognition of, 226- Follicular center cell lymphoma, flow 227, 229 cytometric analysis in, 260 transfusion of, 665 Food and Drug Administration, Fibronectin, integrin recognition of, 226- transfusion medicine regulation by, 227 836-838 Ficoll-Hypaque technique, 268 Fragile X syndrome, prenatal diagnosis of, Fifth disease (parvovirus B19 infection), in 499 blood transfusion components, 763 Fungal infections. See specific infection. prenatal diagnosis of, 511-512, 537 Fy antigens, in hemolytic disease of Filtration, of transfusion components, for newborn, 557 microbial removal, 791-792 Flow cytometry, in cell cycle analysis, 174-177, 186-190 in HIV testing, 318 Gamete intrafallopian transfer, ethical and in lymphocyte marker analysis, 237-275 legal considerations in, 430-432 antibody labeling techniques in, 263- Gamma globulin, in neonatal alloimmune 266 thrombocytopenia, 584-585 biohazards precautions in, 274 in plasmapheresis, 599 cell fixation for, 273 Gamma irradiation, of transfusion cell gating settings for, 243-244 components, for microbial cell labeling for, 269-273 inactivation, 794-795 compensation settings for, 241, 243 in graft-versus-host disease preven- computer data acquisition in, 239 tion, 750-751 fluorochromes for, 245-246, 271-273 Gangliosides, 64-75 in B-cell prolymphocytic leukemia, antibodies to, detection of, 72-75 260 diseases associated with, 70 in chronic lymphocytic leukemia, 258, mechanism of action of, 72 260 origin of, 71-72 in follicular center cell lymphoma, 260 pathogenicity of, 71 in hairy cell leukemia, 260 specificity of, 70-71 in plasmacytoid lymphocytic lym- characteristics of, 70 phoma, 260 molecular structure of, 65 in T-cell chronic lymphoproliferative tissue localization of, 65, 70 disease, 260, 262 Gene-dosage methods, in linkage instrumentation for, 238-245 analysis, 455-456 monoclonal antibodies for, 246-247 Gene mapping. See under Liiikage analysis. procedure for, 263-274 Genetic disease. See also Congenital quality control in, 244-245, 273-274 disease. results interpretation in, 247, 255-263 diagnosis of, 493-502 settings in, 239-244 alpha-fetoprotein markers in, 481-492 specimen handling in, 266-269 chromosomal syndromes, 497-499 technical problems in, 262-263 efficacy of methods for, 500-501 voltage gain settings for, 239-241 genomic imprinting and, 499-500 870 CUMULATIVE INDEX 1992 Genetic disease (Continued) testing in, CDNA sequencing, 297 in assisted reproductive technology, NADPH oxidase component gene 495 characterization, 293, 295 indications for, 496-497 Northern analysis, 296 overview of, 493-494 polymerase chain reaction, 297 preconceptive, 495-496 prer.atal, 297-299 techniques for, 494-495, 500-501 Southern analysis, 296 with fetal cells in maternal blood, 496 Growth factors, hematopoietic, as prediction of, linkage analysis in, 449- transfusion alternatives, 777-778 462 receptors for, in tumor, monoclonal an- counseling in, 458-460 tibodies directed to, 210-211 definitions in, 450 Guillain-Barré syndrome, in blood donors, gene mapping methods in, 450-458 guidelines for, 678 Human Genome Initiative project, plasmapheresis in, 599-600 460 Tay-Sachs disease, 463-480 recurrent spontaneous miscarriage and, 406 Hairy cell leukemia, flow cytometric Gestational age, alpha-fetoprotein results analysis in, 260 and, 486 Halogenated pyrimidine incorporation GIFT (gamete intrafallopian transfer), method, in cell cycle analysis, 179, ethical and legal considerations in, 190 430-432 Hamster test (sperm penetration assay), Glioblastoma multiforme, integrins in, 402-403 220-221 Hazardous waste disposal, regulations on, Glioma, immunotherapy in, monoclonal 841 antibodies in, 209-210 Health Care Financing Administration, Glucose, in embryo culture media, 423 transfusion medicine regulation by, Glucose—6-phosphate dehydrogenase 838-840 deficiency, defective respiratory burst Heart, transplantation of, rejection in, 284-285 markers in, 106, 108-109 Glue, fibrin, in hemostasis, 777 Heat shock protein 90, antibodies to, in Glutathione reductase deficiency, rheumatic disease, 6 defective respiratory burst in, 285 Heat treatment, of transfusion GM, ganglioside, in Tay-Sachs disease, components, for microbial 466-467 inactivation, 791 Gonorrhea, prenatal diagnosis of, 527-528 Hemagglutination test, in syphilis, 529- Goodpasture’s syndrome, plasmapheresis 530 in, 600 in toxoplasmosis, 541 Graft-versus-host disease, in transfusion, Hemapheresis. See also Plasmapheresis. 718, 749-751 Granulocyte-macrophage colony- in pregnancy, 587-602 in dermatologic disease, 601 stimulating factor, in cancer in gastrointestinal disease, 601 immunotherapy, 205 Granulocyte-monocyte colony stimulation in hematologic disease, 593-598 factor, as transfusion alternative, 778 in neurologic disorders, 599-600 Granulomatous disease, 277-305 in renal disease, 600 autoantibodies in, 87, 89 in rheumatologic disease, 600 carrier state of, diagnosis of, 292-293 indications for, 587 classification of, 280-281, 284, 292, 294 machine (centrifugal), 588 clinical features of, 289, 292-293 manual, 588 incidence of, 280 nontreatment, 592-593 infections in, 288-289, 292 replacement solutions for, 598-599 pathogenesis of, 280-288 technique for, 592 phagocyte respiratory burst and, defec- technology for, 587-588 tive, 280-288 therapeutic, 593-601 normal, 277-280 volume calculations for, 588-592 regulation of, 279-280 Hematocrit, extremely low, death in, 656 prenatal diagnosis of, 513-514 Hematologic disorders. See under Blood.

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