Clinical Pain Management Chronic Pain LEAD EDITOR Andrew SCRiceMBBSMD FRCA Reader inPainResearch, Department ofAnaesthetics, PainMedicineandIntensive Care Imperial College London; andHonoraryConsultant inPainMedicine, Chelsea and WestminsterHospital FoundationNHS Trust, London,UK SERIES EDITORS DouglasJustins MBBSFRCA Fellowofthe FacultyofPainMedicine ofthe Royal College ofAnaesthetists Consultantin PainMedicine andAnaesthesia PainManagement Centre StThomas’ Hospital London,UK TobyNewton-John BA(Hons)MPsych(Clin)PhD ConsultantClinical Psychologist andProgram Director Innervate PainProgramand Faculty ofMedicine, University ofSydney Australia RichardF HowardBScMBChB FRCA Fellowofthe FacultyofPainMedicine ofthe Royal College ofAnaesthetists Consultantin Paediatric Anaesthesia andPain Management Great Ormond Street Hospitalfor Children London,UK Christine AMiaskowski RNPhDFAAN Professor andAssociate Deanfor Academic Affairs Department ofPhysiologicalNursing UCSF SchoolofNursing SanFrancisco,CA, USA Acute Pain EditedbyPamelaE Macintyre, Suellen MWalker,and David J Rowbotham Chronic Pain EditedbyPeter RWilson,PaulJ Watson, Jennifer AHaythornthwaite, and TroelsSJensen Cancer Pain EditedbyNigel Sykes, MichaelIBennett, and Chun-Su Yuan Practice and Procedures EditedbyHarald Breivik, WilliamICampbell, and Michael KNicholas Clinical Pain Management Chronic Pain 2nd edition Edited by Peter R Wilson Professor of Pain Medicine Mayo Clinic College of Medicine Rochester, USA Paul J Watson Professor of Pain Management and Rehabilitation Department of Health Sciences University of Leicester Leicester, UK Jennifer A Haythornthwaite Professor Department of Psychiatry and Behavioral Sciences Johns Hopkins Medical Institutions Baltimore, USA Troels S Jensen Professor Experimental and Clinical Pain Research Department of Neurology and Danish Pain Research Center Aarhus University Denmark FirstpublishedinGreatBritainin2003 Thissecondeditionpublishedin2008by HodderArnold,animprintofHodderEducation, partofHachetteLivreUK,338EustonRoad,LondonNW13BH http://www.hoddereducation.com &2008HodderandStoughtonLimited Allrightsreserved.ApartfromanyusepermittedunderUKcopyrightlaw,thispublicationmayonlybe reproduced,storedortransmitted,inanyform,orbyanymeanswithpriorpermissioninwritingofthepublishers orinthecaseofreprographicproductioninaccordancewiththetermsoflicencesissuedbytheCopyright LicensingAgency.IntheUnitedKingdomsuchlicencesareissuedbytheCopyrightLicensingAgency:Saffron House,6-10KirbyStreet,LondonEC1N8TS. 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BritishLibraryCataloguinginPublicationData AcataloguerecordforthisbookisavailablefromtheBritishLibrary LibraryofCongressCataloging-in-PublicationData AcatalogrecordforthisbookisavailablefromtheLibraryofCongress ISBN978-0-340-94009-9(AcutePain) ISBN978-0-340-94008-2(ChronicPain) ISBN978-0-340-94007-5(CancerPain) ISBN978-0-340-94006-8(PracticeandProcedures) ISBN978-0-340-93992-5(4volset:AcutePain/ChronicPain/CancerPain/PracticeandProcedures/Webedition) 12345678910 CommissioningEditor: JoannaKoster ProjectEditor: ZelahPengilley ProductionController: JoannaWalker CoverDesign: HelenTownson Typesetin10ptMinionbyMacmillanIndia PrintedandboundintheUKbyMPGBooks,Bodmin,Cornwall TextprintedonFSCaccreditedmaterial Whatdoyouthinkaboutthisbook?OranyotherHodderArnoldtitle? Pleasevisitourwebsite:www.hoddereducation.com Contents Contributors ix Series preface xiii Introduction toClinical Pain Management: Chronic Pain xv Howto usethis book xvii Abbreviations xix PART IGENERAL CONSIDERATIONS 1 1 Applied physiology:neuropathicpain 3 Victoria CJWallaceandAndrew SCRice 2 Applied physiology:persistentmusculoskeletal pain 24 Hans-Georg Schaible 3 Applied physiology:persistentvisceral pain 37 Timothy JNess 4 Geneticsofchronicpain:crucial conceptsin geneticsandresearch toolstounderstandthe 48 molecularbiologyofpain andanalgesia BradleyEAouizeratandChristineAMiaskowski 5 Epidemiology ofchronicpain:classical tomolecularapproachesto understanding theepidemiology ofpain 65 Cielito Reyes-Gibby, IsabelTorres-Vigil, andRoy Croock 6 The economicsofchronicpain 75 CeriJ Phillips 7 The challengesofpain andsuffering 86 DavidBMorris andPeter RWilson 8 Paininsociety: ethical andlegalperspectives 99 BenARich 9 Chronicpain, impairment,anddisability 115 Robert JGatchel andNancyD Kishino 10 The psychological assessment ofpain in patients withchronicpain 122 Allen HLebovits 11 Assessmentofthepatient withneuropathicpain 132 HanneGottrup and Troels S Jensen 12 Diagnostic proceduresin chronicpain 145 NikolaiBogduk 13 Psychological effects ofchronicpain:anoverview 169 LanceMMcCracken 14 Outcome measurement inchronicpain 178 Tim Johnson vi]Contents PART IIMANAGEMENT –THERAPIES 191 15 The use ofNSAIDsandparacetamol (acetaminophen) in chronicpain 193 John Hughes andKRiazKhan 16 Opioids andchronicnoncancer pain 207 CRoger GouckeandEricJ Visser 17 Topical analgesicsforneuropathic pain 230 Charles EArgoff andKRiazKhan 18 Chronicpain anddepression 241 W MichaelHooten 19 Antiepileptic andantiarrhythmic agents 254 TuroJNurmikko 20 Neurostimulation techniques 268 Marc AHuntoon 21 Spinal administration 284 KateGradyandJon Raphael 22 Cognitive-behavior therapyfor chronicpain inadults 292 Stephen MorleyandChristopher Eccleston 23 Evaluation ofcomplementary andalternative therapies 303 Miles J Belgradeand CassandraDSchamber PART IIIMANAGEMENT –CLINICALSITUATIONS 321 24 Painin neurological disease 323 PaulR Nandi 25 Peripheral neuropathies 335 RavikiranShenoy, Katherine Roberts,andPraveen Anand 26 HIVandAIDS 352 Sarah Cox andAndrew SCRice 27 Complexregional pain syndromes 362 PeterR Wilson 28 Central neuropathicpain:syndromes, pathophysiology,andtreatments 374 James CWatson 29 Spinal cordinjury 388 Philip J Siddalland Paul J Wrigley 30 Chronicpain after surgery 405 William MacraeandJulie Bruce 31 Postamputationpain 414 Lone Nikolajsenand Signe Koch 32 Herpes zoster pain including shinglesandpostherpetic neuralgia 429 Robert WJohnson 33 Management ofpainfulspasticity 440 Barry Rawicki 34 Headache 450 Peer Tfelt-Hansen andRigmorJensen 35 Facial pain 467 PeterSvensson andLene Baad-Hansen 36 Neck painandwhiplash 484 NikolaiBogduk 37 Chronicbackpain 501 Randy AShelerud Contents ]vii 38 Chronicjointpain 518 Tanya Baqai,Ali Jawad,and BruceKidd 39 Therapies forchronicchestpain 537 IvanN Ramos-Galvezand GlynRTowlerton 40 Chronicabdominal, groin,andperineal pain ofvisceral origin 549 Timothy J Ness 41 Chronicpelvicpain 570 Andrea J RapkinandMonica Lee 42 Fibromyalgia andmyofascial pain:mechanisms tomanagement 599 SerenaF Carvilleand ErnestHChoy 43 Psychiatric diagnosis andchronicpain 614 Stephen PTyrer 44 Chronicpain in children 623 Navil FSethna, Alyssa Lebel, andLisa Scharff 45 Principles ofchronicpain therapyin elderly patients 641 John Hughes andChris Dodds 46 Painmanagement andsubstance misuse 652 Cathy Stannard Index 661 Pleasenote:ThetableofcontentsandacombinedindexforallfourvolumesintheseriescanbefoundontheClinicalPainManagement website at:www.clinicalpainmanagement.co.uk. This page intentionally left blank Contributors Praveen AnandMAMDFRCP Julie Bruce RGNBScMscPhD Professor ofClinical Neurology MRCSenior ResearchFellow Division ofNeuroscienceandMental Health, Imperial College Department ofPublic Health,School ofMedicine,College ofLife London,Hammersmith Hospital,London, UK Sciences andMedicine,University ofAberdeen Aberdeen, UK BradleyEAouizerat PhDMAS SerenaF CarvillePhD Assistant Professor Programme Manager School ofNursing andTheInstitute forHumanGenetics UK Age ResearchForum, London,UK University ofCalifornia,SanFrancisco,CA, USA Ernest HChoyMDFRCP CharlesEArgoff MD Reader inRheumatology Professor ofNeurology Department ofAcademic Rheumatology, King’s College London Albany MedicalCollege London,UK Director Comprehensive Pain Program,Albany MedicalCollege Sarah CoxMBBSBScFRCP Consultantin Palliative Medicine NewYork, USA Chelsea andWestminsterHospitalNHS Foundation Trust; and TrinityHospice, London,UK Lene Baad-Hansen DDSPhD Assistant Professor Roy CroockBS Department ofClinical OralPhysiology, School ofDentistry Research Assistant Faculty ofHealth Sciences, UniversityofAarhus Department ofEpidemiology, The UniversityofTexasMD Aarhus,Denmark AndersonCancer Center, Houston,TX, USA Chris DoddsMBBSMRCGPFRCA TanyaBaqai MBChBMRCP Professor Specialist Registrar Department ofAnaesthesia, SouthTees Hospitals NHS Trust Department ofRheumatology, Royal LondonHospital Middlesborough, UK London,UK Christopher Eccleston PhD Miles J BelgradeMD Professor ofPsychologyandDirector MedicalDirector ofFairview Painand Centre for Pain Research,The University ofBath,Bath, UK Palliative Care Center RobertJ GatchelPhDABPP University ofMinnesota MedicalCenter;and Chairman AdjunctProfessor Department ofPsychology,College ofScience at Department ofNeurology,University ofMinnesota Medical The University ofTexasatArlington; and School, Minneapolis,USA Director ofClinical Research The Eugene McDermottCenter for Pain Management NikolaiBogduk BSc(Med)MBBSPhDMDDScDipAnatMMed(Pain)FAFRMFFPM The University ofTexasSouthwestern MedicalCenter atDallas (ANZCA) Arlington, TX,USA Conjoint ProfessorofPainMedicine University ofNewcastle,Newcastle BoneandJointInstitute Hanne Gottrup MDPhD Royal Newcastle Centre, Newcastle Department ofNeurology andDanishPainResearchCenter NewSouthWales,Australia AarhusUniversity Hospital, A˚rhus, Denmark
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