Clinical Endocrinology 1999: Vol 51 Table of Contents

7 Pages·1999·1.4 MB·English

Clinical Endocrinology (1999) 51, iii—viii
Contents
Volume 51, Number 1, July 1999 immunoglobulins in goitrous and agoitrous autoimmune
thyroiditis after twelve months of L-thyroxine therapy:
D.H.C. KHOO, P.H.K. ENG, S.C. HO AND A.C.K. FOK
Review
Serum leptin levels in healthy ageing men: are decreased
Apoptosis in neuroendocrine tumours: D.G. WANG serum testosterone and increased adiposity in elderly men
the consequence of leptin deficiency?:
J.K. VAN DEN SAFFELE, S. GOEMAERE, D. DE BACQUER
Commentary
AND J.M. KAUFMAN
Practice guidelines for the detection and management of Reduced human growth hormone (hGH) bioactivity
thyroid dysfunction. A comparative review of the without a defect of the GH-1 gene in three patients with
recommendations: J.—E. ARBELLE AND A. PORATH rhGH responsive growth failure: G. BINDER, M.R. BENZ,
Mapping of a novel tumour suppressor gene with a role in M. ELMLINGER, C.D. PFLAUM, C.J. STRASBURGER AND
neuroendocrine tumours: s.H.S. PEARCE (see page 27) M.B. RANKE
Mutation screening and isoform prevalence of the follicle
stimulating hormone receptor gene in women with
Rapid communication
premature ovarian failure, resistant ovary syndrome and
Growth hormone replacement therapy in adults with polycystic ovary syndrome: G.s. CONWAY, E. CONWAY,
growth hormone deficiency improves vascular reactivity: C. WALKER, W. HOPPNER, J. GROMOLL AND M. SIMONI
E.R. CHRIST, P.J. CHOWIENCZYK, P.H. SONKSEN AND Type | multiple endocrine neoplasia (MEN1):
D.L. RUSSEL-JONES contribution of genetic analysis to the screening and
follow-up of a large French kindred: c. WATERLOT,
N. PORCHET, C. BAUTERS, M. DECOULX, J.L. WEMEAU,
Original papers
C. PROYE, P.M. DEGAND, J.P. AUBERT, C. CORTET AND
Frequent loss of heterozygosity at chromosome D. DEWAILLY
3p14-2-3p21 in human pancreatic islet cell tumours: Incidentally discovered pituitary lesions: high freqency of
M.N. NIKIFOROVA, Y.E. NIKIFOROV, P. BIDDINGER, macroadenomas and hormone-secreting adenomas —
D.R. GNEPP, L.A. GROSEMBACHER, B.L. WAJCHENBERG, results ofa prospective study: J. FELDKAMP, R. SANTEN,
J.A. FAGIN AND R.M. COHEN (see commentary page 19) E. HARMS, A. AULICH, U. MODDER AND W.A. SCHERBAUM
Evaluation of bone metabolism after the use of an inhaled Association of the large multifunctional proteasome
glucocorticoid (flunisolide) in patients with moderate (LMP2) gene with Graves’ disease is a result of linkage
asthma: O.M. HAUACHE, E.C.J. AMARANTE, J.G.H. VIEIRA, disequilibrium with the HLA haplotype DRB1*0304-
S.M. FARESIN, A.L.G. FERNANDES, J.R. JARDIM AND DQB1*02-DQA1*0501: J.M. HEWARD, A. ALLAHABADIA,
M. LAZARETTI-CASTRO M.C. SHEPPARD, A.H. BARNETT, J.A. FRANKLYN AND
Short-term leptin infusion does not affect circulating S.C.L. GOUGH
levels of LH, testosterone or cortisol in food-restricted Macroprolactinaemia: validation and application of the
pubertal male rhesus macaques: J. LADO-ABEAL, polyethylene glycol precipitation test and clinical
Y.0. LUKYANENKO, S. SWAMY, R.C. HERMIDA, characterisation of the condition: A.o. OLUKOGA AND
J.C. HUTSON AND R.L. NORMAN J.W. KANE
Effects of growth hormone replacement on physical
performance and body composition in GH deficient adults:
Case report
J. RODRIGUEZ-ARNAO, A. JABBAR, K. FULCHER,
G.M. BESSER AND R.J.M. ROSS Ovarian responses to hCG stimulation: insulin resistance/
Growth hormone status following treatment for Cushing’s hyperinsulinaemia vs. insulin deficiency: s.F. WITCHEL
syndrome: N.R. HUGHES, C.A. LISSETT AND S.M. SHALET AND S. ARSIANIAN
Salivary cortisol for screening of Cushing’s syndrome in
children: C.E. MARTINELLI, S.L. SADER, E.B. OLIVEIRA, Letters to the Editors
J.C. DANELUZZI AND A.C. MOREIRA
Differences in the levels of TSH-binding inhibitor Book review
iv Contents
The continuous 7-hour intravenous dexamethasone
137 Notices suppression test in the differential diagnosis of ACTH-
dependent Cushing’s syndrome:
Author’s Declaration D.P.M. VAN DEN BOGAERT, W.W. DE HERDER
F.H. DE JONG, P. BIEMOND, A.J. VAN DER LELY AND
S.W.J. LAMBERTS
Volume 51, Number 2, August 1999 Leptin serum concentrations in healthy neonates within
the first week of life: relation to insulin and growth
hormone levels, skinfold thickness, body mass index and
Review
weight: C. SCHUBRING, T. SIEBLER, J. KRATZSCH,
Role of FSH in the regulation of spermatogenesis: clinical P. ENGLARO, W.F. BLUM, K. TRIEP AND W. KIESS
aspects: E. NIESCHLAG, M. SIMONI, J. GROMOLL AND Sleep deprivation effects on the activity of the
G.F. WEINBAUER hypothalamic—pituitary—adrenal and growth axes:
potential clinical implications: A.N. VGONTZAS
G. MASTORAKOS, E.O. BIXLER, A. KALES, P.W. GOLD AND
Commentary
G.P. CHROUSOS
Non-islet cell tumour hypoglycaema: J.D. TEALE (see Vitamin D insufficiency increases bone turnover markers
page 247) and enhances bone loss at the hip in patients with
The role of bilateral inferior petrosal sinus sampling in the established vertebral osteoporosis: 0. SAHOTA, T. MASUD
investigation of ACTH-dependent hypercortisolism: P. SAN AND D.J. HOSKING
A.B. ATKINSON (see page 255) Syndrome of body fat redistribution in HIV-1-infected
The short synacthen test: is less best?: P.M. STEWART AND patients: relationships to cortisol and catecholamines:
P. CLARK (see page 153) E. RENARD, J. FABRE, F. PARIS, J. REYNES AND
j. BRINGER
The effects of metformin on insulin resistance and ovarian
Original papers
steroidogenesis in women with polycystic ovary
Reproducibility of the cortisol response to stimulation syndrome: kK. UNLUHIZARCI, F. KELESTIMUR, F. BAYRAM,
with the low dose (1 wg) of ACTH: y.J. PARK, K.S. PARK Y. SAHIN AND A. TUTUS
J.H. KIM, C.S. SHIN, S.Y. KIM AND H.K. LEE (see Neuromuscular symptoms and dysfunction in subclinical
commentary page 151) hypothyroid patients: beneficial effect of L-T,
Comparison of six months therapy with octreotide versus replacement therapy: F. MONZANI, N. CARACCIO
lanreotide in acromegalic patients: a retrospective study: P. DEL GUERRA, A. CASOLARO AND E. FERRANNINI
P. RAZZORE, A. COLAO, R. BALDELLI, D. GAIA Association of molecular variants of luteinizing hormone
P. MARZULLO, E. FERRETTI, D. FERONI with menstrual disorders: L.N. RAMANUJAM, W.X. LIAO
M.L. JAFFRAIN-REA, G. TAMBURRANO, G. LOMBARDI A.C. ROY. A. LOGANATH, H.H. GOH AND S.C. NG
F. CAMANNI AND E. CICCARELLI
A novel mutation in the TPO gene in goitrous hypothyroid
patients with iodide organification defect: C.L.s. SANTOS Case report
H. BIKKER, K.G.M. REGO, A.C. NASCIMENTO Hypoglycaemia associated with the production of insulin-
M. TABASCIA, J.J.M. DE VIJLDER AND G. MEDEIROS-NETO like growth factor II and insulin-like growth factor binding
Growth hormone (GH) replacement therapy reduces protein 6 by a haemangiopericytoma: K. HOEKMAN
serum sialic acd concentrations in adults with GH-
J. VAN DOORN, T. GLOUDEMANS, J.A. MAASSEN,
deficiency: a double-blind placebo-controlled study:
4.G.P. SCHULLER AND H.M. PINEDO (see commentary page
E.R. CHRIST, M.H. CUMMINGS, P.J. LUMB, M.A. CROOK
147)
P.H. SONKSEN AND D.L. RUSSELL-JONES
Classical pituitary apoplexy: clinical features,
Letters to the Editors (see commentary page 149)
management and outcome: H.S. RANDEVA, J. SCHOEBEI
J BYRNE, M. ESIRI, C.B.T. ADAMS AND J.A.H. WASS
Ontogeny of serum leptin concentrations in the human: Book review
M. GEARY, R. HERSCHKOVITZ, P.J. PRINGLE, C.H. RODECK
AND P.C. HINDMARSH Author’s Declaration
Contents Vv
Volume 51, Number 3, September 1999 Splanchnic exchange of insulin-like growth factor binding
protein-1 (IGFBP-1), IGF-I and acid-labile subinit (ALS)
during normo- and hyper-insulinaemia in healthy subjects:
Editorial
E. FERNQVIST-FORBES, K. EKBERG, B.F. LINDGREN AND
Role of postoperative radiotherapy in the treatment of K. BRISMAR
pituitary tumours: A.B. GROSSMAN AND The quality of life of adults with growth hormone
P. KENDALL-TAYLOR deficiency: comparison with diabetic patients and control
subjects: M. WALLYMAHMED, P. FOY AND
Review I1.A. MACFARLANE
Serum IGF-I and IGFBP-3 concentrations do not
Pituitary adenoma radiotherapy — when and how?:
accurately predict growth hormone deficiency in children
P.N. PLOWMAN
with brain tumours: S.A. WEINZIMER, S.A. HOMAN,
R.J. FERRY AND T. MOSHANG
Commentary Lipid profile, glucose tolerance and insulin sensitivity
after more than four years of growth hormone therapy in
Toward better treatment of congenital adrenal hyperplasia:
non-growth hormone deficient adolescents: p. BAREILLE,
P.W. SPEISER - (see page 285)
C. AZCONA, D.R. MATTHEWS, G.S. CONWAY AND
R. STANHOPE
Rapid communication
Mutations in intron 3 of GH-1 gene associated with
A comparison of lanreotide and octreotide LAR for isolated GH deficiency type II in three Japanese families:
treatment of acromegaly: H.E. TURNER, A. VADIVALE, T. KAMIJO, Y. HAYASHI, A. SHIMATSU, E. KINOSHITA
J, KEENAN AND J.A.H. WASS M. YOSHIMOTO, M. OGAWA AND H. SEO
The prevalence of thyroid dysfunction in a population with
borderline iodine deficiency: N. KNUDSEN, T. JORGENSEN
Original papers
S. RASMUSSEN, E. CHRISTIANSEN AND H. PERRILD
Audit of selected patients with non-functioning pituitary Hexarelin as a test of pituitary reserve in patients with
adenomas treated without irradiation — a follow-up study: pituitary disease: M. KORBONITS, G. KALTSAS,
H.E. TURNER, I.M. STRATTON, J.V. BYRNE, C.B.T. ADAMS L.A. PERRY, A.B. GROSSMAN, J.P. MONSON, G.M. BESSER
AND J.A.H. WASS AND P.J. TRAINER
Effect of carbenoxolone on the plasma renin activity and
hypothalamic—pituitary—adrenal axis in congenital
Case report
adrenal hyperplasia due to 21-hydroxylase deficiency:
I. IRONY AND G.B. CUTLER - (see commentary page 273) Pituitary apoplexy following metastasis of bronchogenic
Increased pressor response to noradrenaline in pituitary adenocarcinoma to a prolactinoma: F.W.F. HANNA,
dependent Cushing’s syndrome: a.P. HEANEY, O.M. WILLIAMS, J.S. DAVIES, T. DAWSON, J. NEAL AND
S.J. HUNTER, B. SHERIDAN AND A.B. ATKINSON M.F. SCANLON
The relationship among circulating insulin-like growth
factor components, biochemical markers of bone turnover Book reviews
and bone mineral density in postmenopausal women under
the age of 60: J.G. KIM, C.S. SHIN, Y.M. CHOI, S.Y. MOON, Author’s Declaration
S.Y. KIM AND J.Y. LEE
Growth hormone (GH) status is an independent
determinant of serum levels of cholesterol and
triglycerides in healthy adults: N. VAHL, I. KLAUSEN
J.S. CHRISTIANSEN AND J.0.L. JORGENSEN Volume 51, Number 4, October 1999
p16 (INK4*, MTS-1) gene polymorphism and methylation
status in human pituitary tumours: M.L. JAFFRAIN-REA,
Commentary
E. FERRETTI, E. TONIATO, K. CANNITA, A. SANTORO,
D. DI STEFANO, E. RICEVUTO, M. MARODER, 385 Hypogonadotrophic hypogonadism: a unique biological
G. TAMBURRANO, G. CANTORE, A. GULINO AND
opportunity: S. SEMINARA AND W.F. CROWLEY (see page
S. MARTINOTTI 525)
Contents
Original papers in amenorrhoeic growth hormone deficient women:
J.A.M. DE BOER, E.A. VAN DER VEEN AND
Postmenopausal osteoporosis is more related to hormonal
J. SCHOEMAKER
aberrations than to lifestyle factors:
Enhancement of the GH responsiveness to GH releasing
K. LANDIN-WILHELMSEN, L. WILHELMSEN AND
stimuli by lysine vasopressin in type | diabetic subjects:
B.A. BENGTSSON V. COIRO, R. VOLPI, L. CAPRETTI, G. SPERONI,
Increased prevalence of type 2 diabetes mellitus and
G. CAFFARRI, C. MARCHESI AND P. CHOIDERA
impaired glucose tolerance in first-degree relatives of girls
Osteoporosis and fractures in Turner syndrome
with a history of precocious pubarche: L. IBANEZ
importance of growth promoting and oestrogen therapy:
C. CASTELL, R. TRESSERRAS AND N. POTAI
K. LANDIN-WILHELMSEN, I. BRYMAN, M. WINDH AND
RADS] as a candidate parathyroid tumour supressor gene
L. WILHELMSEN
on chromosome 15q: absence of somatic mutations:
The course of Graves’ ophthalmopathy is not influenced
T. CARLING, Y. IMANISHI, R.D. GAZ AND A. ARNOLD
by near total thyroidectomy: a case-control study:
Acute dexamethasone administration enhances GH
C. MARCOCCI, G. BRUNO-BOSSIO, L. MANETTI,
responsiveness to GH releasing peptide- 6 (GHRP-6) in
M.L. TANDA, P. MICCOLI, P. IACCONI, M.P. BARTOLOMEI,
man: A.C.A.R. PINTO, F.E. FINAMOR AND A.M.J. LENGYEI
M. NARDI, A. PINCHERA AND L. BARTALENA
Effects of short-term hormone replacement on serum
Sensitivity and specificity of the fine need aspiration
leptin levels in postmenopausal women: H.B. LAVOIE
biopsy of the thyroid: clinical point of view: J. CAP,
A.E. TAYLOR, J.L. SHARPLESS, E.J. ANDERSON, A. RYSKA, P. REHORKOVA, E. HOVORKOA, Z. KEREKES
C.C. STRAUSS AND J.E. HALL
AND D. POHNETALOVA
The insulin-like growth factor-I (IGF-I) gene in
Role of oestrogen in male sexual behaviour: insights from
individuals born small for gestational age (SGA):
the natural model of aromatase deficiency: C. CARANI,
L.B. JOHNSTON, J. LEGER, M.O. SAVAGE, A.J.L. CLARK
V. ROCHIRA, M. FAUSTINI-FUSTINI, A. BALESTRIERI AND
AND P. CZERNICHOW
A.R.M. GRANATA
Postpartum thyroid dysfunction: clinical assessment and
relationship to psychiatric affective morbidity: G.N. KENT
B.G.A. STUCKEY, J.R. ALLEN, T. LAMBERT AND V. GEI Case report
Abnormal circadian rhythm and increased non-pulsatile
Gordon Holmes spinocerebellar ataxia: a gonadotrophin
secretion of thyrotrophin in Sheehan’s syndrome:
deficiency syndrome resistant to treatment with pulsatile
P. MACCAGNAN, J.H.A. OLIVEIRA, V. CASTRO AND J. ABUCHAM
gonadotrophin-releasing hormone: R. QUINTON,
Effects of administration of 178-oestradiol on serum leptin
P. BARNETT, P. COSKERAN AND P.M.G. BOULOUX — (see
levels in healthy postmenopausal women: J.M.H. ELBERS
commentary page 385)
G.W. DE VALK-DE-ROO, C. POPP-SNIJDERS
A. NICOLAAS-MERKUS, E. WESTERVEEN, B.W. JOENJE AND
Author’s Declaration
|. COEN NETELENBOS
Sexual dimorphism in circulating monomeric and dimeric
inhibins in normal boys and girls from birth to puberty:
I. BERGADA, G. ROJAS, G. ROPELATO, S. AYUSO
Volume 51, Number 5, November 1999
C. BERGADA AND S. CAMPO
lopanoic acid-induced decrease of circulating T3 causes a
Commentary
significant increase in GH responsiveness to GH releasing
hormone in thyrotoxic patients: J.c. RAMOS-DIAS AND Aetiology-specific effect of premature ovarian failure on
A.M.J. LENGYEI bone mass — is residual ovarian function important?: s.J
Extrusion of testosterone pellets: a randomized controlled HOWELL AND S.M. SHALET
clinical study: s. KELLEHER, L. TURNER, C. HOWE,
A.J. CONWAY AND D.J. HANDELSMAN
Rapid communication
Assessment of cortisol and ACTH responses to the
desmopressin test in patients with Cushing’s syndrome Relationship between ovarian cortisol:cortisone ratios and
and simple obesity: s. TSAGARAKIS, V. VASILIOU, the clinical outcome of in vitro fertilization and embryo
P. KOKKORIS, G. STAVROPOULOS AND N. THALASSINOS transfer (IVF-ET): A.E. MICHAEL, T.D. COLLINS,
GH substitution does not alter the pulsatile pattern of LH D.P. NORGATE, L. GREGORY, P.J. WOOD AND B.A. COOKE
Contents vii
Original papers 619 Long term results of octreotide-therapy in severe dumping
3 es . syndrome: J. VECHT, C.B.H.W. LAMERS AND
In vitro and in vivo responses to short-term recombinant
A.A.M. MASCLEE
human insulin-like growth factor-I (IGF-I) in a severely Z c , —
; eer 25 The lpg short Synacthen test in chronic fatigue syndrome:
growth-retarded girl with ring chromosome 15 and - r
M. HUDSON AND A.J. CLEARE
deletion of a single allele for the type 1 IGF receptor gene: 3 s 5 :
: Malignant human renin producing paraganglioma —
L. DE LACERDA, J.A.R. CARVALHO, B. STANNARD, ie oes ac. ne
localization with “~I- MIBG and treatment with “°'I-
H. WERNER, M.C.S. BOGUSZEWSKI, R. SANDRINI,
MIBG: s. ARVER, H. JACOBSSON, B. CEDERMARK,
S.N. MALOZOWSKI, D. LEROITH AND
B. HAMBERGER, G. LUNDELL, L. GRIMELIUS AND
L.E. UNDERWOOD K. BRISMAR
How many test are required to diagnose growth hormone
nig ; 37 The effect of melatonin administration on pituitary
(GH) deficiency in adults: C.A. LISSETT, P ;
hormone secretion in man: M.L. FORSLING, M.J. WHEELER
E.G.E. THOMPSON, A. RAHIM, B.M.D. BRENNAN AND
AND A.J. WILLIAMS
S.M. SHALET
; a ad 3 . 3 The effects of six months treatment with a low-dose of
Serum leptin and body composition in children with i :
i see ana - : aah conjugated oestrogens in menopausal women:
familial GH deficiency (GHD) due to a mutation in the P
W. SCHLEGEL, L.I. PETERSDORF, R. JUNKER, H. SCHULTE
growth hormone-releasing hormone (GHRH) receptor:
C. EBERT AND A. VON ECKARDSTEIN
E.S.DE A. BARRETTO, M.S. GILL, M.E.S. DE FREITAS, J ae
; ACTH and cortisol release following intravenous
M.M.G. MAGALHAES, A.H.O. SOUZA,
desmopressin: a dose-response study: L.v. sCoTT,
M.H. AGUIAR-OLIVEIRA AND P.E. CLAYTON
Influences on quality of life in GH deficient adults and S. MEDBAK AND T.G. DINAN
The relationship between insulin, IGF-I and weight gain in
their effect on response to treatment: R.D. MURRAY,
cystic fibrosis: A.M. TAYLOR, A. THOMSON,
C.J. SKILLICORN, S.J. HOWELL, C.A. LISSETT, A. RAHIM,
C. BRUCE-MORGAN, M.L. AHMED, A. WATTS, D. HARRIS,
L.E. SMETHURST AND S.M. SHALET
; ; J.M.P. HOLLY AND D.B. DUNGER
lhe relative roles of continuous growth hormone-releasing
hormone (GHRH(1-29)NH>) and intermittent
somatostatin(1-14)(SS) in growth hormone (GH) pulse Case report
generation: studies in normal and post cranial irradiated Ba on ;
Sean Acute pancreatitis and parotitis induced by methimazole in
individuals: J.c. ACHERMANN, P.C. HINDMARSH,
a patient with Grave’s disease: M. TAGUCHI, M. YOKOTA,
1.C.A.F. ROBINSON, D.R. MATTHEWS AND
H. KOYANO, Y. ENDO AND Y. OZAWA
C.G.D. BROOK
Evaluation of the components of insulin-like growth factor
Book review
(IGF)-IGF binding protein (IGFBP) system in adolescents
with type | diabetes and persistent microalbuminuria:
Notices
relationship with increased urinary excretion of IGFBP-3
18 kD N-terminal fragment: A. SPAGNOLI, F. CHIARELLI,
Author’s Declaration
P. VORWERK, B. BOSCHERINI AND R.G. ROSENFELD
Quantitative growth hormone secretion and final adult
height: p.J. TRAINER, M. PALMERMO, J.M.W. KIRK,
G. FANCIULLI, L.H. PERRY, G. DELITALA AND Volume 51, Number 6, December 1999
G.M. BESSER
High serum leptin levels in children with type | diabetes
Review
mellitus: contribution of age, BMI, pubertal development
and metabolic status: R. LUNA, R.V. GARCIA-MAYOR, 673 The X chromosome and ovarian failure: R. M. DAVISON,
M. LAGE, A. ANDRADE, J. BARREIRO, M. POMBO, C. J. DAVIS AND G. S. CONWAY
C. DIEGUEZ AND F.F. CASANUEVA
Ultrasonographic evidence of joint thickening reversibility
, ; 2 Original papers
in acromegalic patients treated with lanreotide for 12 9 _
months: A. COLAO, P. MARZULLO, G. VALLONE, 681 Do immunoassays differentially detect different acidity
A. GIACCIO, D. FERONE, E. ROSSI, R. SCARPA, glycoforms of FSH?: R.L. OLIVER, J.W. KANE, A. WAITE,
F. SMALTINO AND G. LOMBARDI J.W.M MULDERS AND W.R. ROBERTSON
viii Contents
Relationship of physical exercise and ageing to growth The study of spontaneous GH secretion after 36-h fasting
hormone production: s.J. HUREL, N. KOPPIKER distinguishes between GH-deficient and normal adults:
J. NEWKIRK, P.R. CLOSE, M. MILLER, R. MARDELI G. AIMARETTI, A. COLAO, G. CORNELI, R. PIVONELLO,
P.J. WOOD AND P. KENDALL-TAYLOR M. MACCARIO, K. MORRISON, C.D. PFLAUM,
Muscle mass and function in thyrotoxic patients before C.J. STRASBURGER, G. LOMBARDI AND E. GHIGO
and during medical treatment: H. NORRELUND, K.Y. HOVE, Polycystic ovaries and associated clinical and biochemical
E. BREMS-DALGAARD, A.G. JURIK, L.P. NIELSEN, features in young women: K.F. MICHELMORE, A.H. BALEN,
S. NIELSEN, S. NIELSEN, J.0.L. JORGENSEN, J. WEEKE AND D.B. DUNGER AND M.P. VESSEY
N. MOLLER Growth response to rhIGF-1 80ug/kg twice daily in
Clinical features of women with resistance to luteinizing children with growth hormone insensitivity syndrome:
hormone: 1.J.P. ARNHOLD, A.C. LATRONICO, relationship to severity of clinical phenotype: c. AZCONA,
M.C. BATISTA, C.R. IZZO AND B.B. MENDONCA M.A. PREECE, S.J. ROSE, N. FRASER, R. RAPPAPORT,
The use of the hypoglycaemic clamp in the assessment of M.B. RANKE AND M.O. SAVAGE
pituitary function: C. SEMAKULA, G. DAMBERG Association of CTLA-4 polymorphism with positive anti-
D. KENDALL AND E.R. SEAQUIST GAD antibody in Japanease subjects with type | diabetes
Effect of recombinant human growth hormone in elderly mellitus: H. HAYASHI, I. KUSAKA, S. NAGASAKA,
osteoporotic women: T. SUGIMOTO, D. NAKAOKA, A. KAWAKAMI, K. ROKKAKU, T. NAKAMURA, T. SAITO,
M. NASU, M. KANZAWA, T. SUGISHITA AND K. CHIHARA M. HIGASHIYAMA, K. HONDA, S. ISHIKAWA AND T. SAITO
The dexamethasone-suppressed corticotrophin-releasing Oestrogens prevent the increase in human serum soluble
hormone stimulation test in anorexia nervosa: M. DUCLOS, interleukin-6 receptor induced by ovariectomy in vivo and
J.B. CORCUFF, P. ROGER AND A. TABARIN decrease its release in human osteoblastic cells in vitro:
Birth weight affects final height in patients treated for G. GIRASOLE, N. GIULIANI, A. BACCHI MODENA,
growth hormone deficiency: E. CACCIARI, S. ZUCCHINI, G. PASSERI AND M. PEDRAZZONI
A. CICOGNANI, P. PIRAZZOLI, A. BALSAMO, S. SALARDI,
A. CASSIO, A. PASINI AND S. GUALANDI
Case report
Initial characterization of the GH—IGF axis and nutritional
status of the Ati Negritos of the Philippines: Cushing’s syndrome due to an ectopic ACTH-secreting
A.B. CLAVANO-HARDING, G.R. AMBLER, C.T. COWELI pituitary tumour mimicking occult paraneoplastic ectopic
S.P. GARNETT, B. AL-TOUMAH, J.C. COAKLEY, K.K.Y. HO ACTH production: H. BETHGE, W. ARLT,
AND R.C. BAXTER U. ZIMMERMANN, G. KLINGELHOFFER, G. WITTENBERG,
Reversibility of endurance training-induced changes on W. SAEGER AND B. ALLOLIO
glucocorticoid sensitivity of monocytes by an acute
exercise: M. DUCLOS, M. MINKHAR, A. SARRIEAU, Letters to the Editors
D. BONNEMAISON, G. MANIER AND P. MORMEDE
Repeated intramuscular injections of testosterone Referees
undecanoate for substitution therapy in hypogonadal men:
E. NIESCHLAG, D. BUCHTER, S. ECKARDSTEIN, Author index
K. ABSHAGEN, M. SIMONI AND H.M. BEHRE
Alterations in hepatic lipase and lipoprotein subfractions Subject index
with transdermal testosterone replacement therapy:
K.C.B. TAN, S.W.M. SHIU AND A.W.C. KUNG Author’s Declaration