Ciba Foundation Symposium 132 - Motor Areas of the Cerebral Cortex

333 Pages·10.695 MB·English

MOTOR AREAS
OF THE
CEREBRAL CORTEX
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132
Ciba Foundation Symposium
MOTOR AREAS
OF THE
CEREBRAL CORTEX
A Wiley - lnterscience Publication
1987
JOHN WILEY & SONS
Chichester . New York . Brisbane . Toronto . Singapore
0 Ciba Foundation 1987
Published in 1987 by John Wiley & Sons Ltd, Baffins Lane,
Chichester, Sussex PO19 lUD, UK.
Ciba Foundation Symposium 132
+
x 323 pages, 66 figures, 2 tables
Library of Congress Cataloging In Publication Data
Motor areas of the cerebral cortex. - (Ciba Foundation
symposium; 132)
“A Wiley-Interscience publication.”
Papers presented at a symposium held at the Ciba
Foundation, London, 24-26 Feb. 1987.
Includes indexes.
1. Motor cortex-Congresses. I. Ciba Foundation.
11. Series.
QP383.M68 1987 599’.01’852 87-19001
ISBN 0 471 91098 8
British Library Cataloguing in Publication Data
Motor areas of the cerebral cortex. - (Ciba Foundation
symposium; 132)
1. Cerebral cortex
I. Ciba Foundation. 11. Series.
612’825 QP383
ISBN 0 471 91098 8
Typeset by Inforum Ltd. Portsmouth
Printed and bound in Great Britain by the Bath Press Ltd, Bath, Avon.
Contents
Symposium on Motor areas of the cerebral cortex, held at the Ciba Foundation,
London, 24-26 February 1987
This symposium is based on a proposal made by Professor R. Porter, Canberra
Editors: Gregory Bock (Orgatiizer), Maeve O’Connor and Joan Marsh
R. Porter Introduction 1
C.G. Phillips Epicortical electrical mapping of motor areas in primates 5
Discussion 16
E.G. Jones Ascending inputs to, and internal organization of, cortical motor
areas 21
Di.scirs.sioti 35
M. Wiesendanger, H. Hummelsheim, M. Bianchetti, D.F. Chen, B. Hyland,
V. Maier and R. Wiesendanger Input and output organization of the
supplementary motor area 40
Discussiori 53
H.G.J.M. Kuypers Some aspects of the organization of the output of the
motor cortex 63
Discussion 75
R. Porter Functional studies of motor cortex 83
Di.scussioti 92
E.E. Fetz and P.D. Cheney Functional relations between primate motor
cortex cells and muscles: fixed and flexible 98
Discussion 112
Genercrl discussion I 118
A.P. Georgopoulos Cortical mechanisms subserving reaching 125
Discir.s.sion 132
V
vi Contents
J. Tanji Neuronal activity in the primate non-primary cortex is different from
that in the primary motor cortex 142
Discussion 147
R.E. Passingham Two cortical systems for directing movement 151
Discussion 161
General discussion 2 165
G. Rizzolatti Functional organization of area 6 171
Discussion 182
P.S. Goldman-Rakic Motor control function of the prefrontal cortex 187
Discussion 197
W.F. Thach Cerebellar inputs to motor cortex 201
Discussion 2 15
General discussion 3 221
L. Deecke Bereitschaftspotential as an indicator of movement preparation
in supplementary motor area and motor cortex 231
Discussion 245
P.E. Roland Metabolic mapping of sensorimotor integration in the human
brain 251
Discussion 265
H.-J. Freund Differential effects of cortical lesions in humans 269
Discussion 276
C.D. Marsden What do the basal ganglia tell premotor cortical areas? 282
Discussion 296
Fitial getieral discussion 30 1
R. Porter Chairman’s closing remarks 310
Index of contributors 313
Subject index 000
Participants
D.M. Armstrong Department of Physiology, University of Bristol Medical
School, University Walk, Bristol BS8 lTD, UK
D.B. Calne Division of Neurology, University of British Columbia, Health
Sciences Centre Hospital, 2211 Wesbrook Mall, Vancouver, British
Columbia, Canada V6T 1W5
P.D. Cheney Department of Physiology, University of Kansas Medical
Center, Kansas City, Kansas 66103, USA
L. Deecke Neurologische Universitatsklinik, Allgemeines Krankenhaus
der Stadt Wien, Lazarettgasse 14, 1097 Vienna, Austria
E.E. Fetz Department of Physiology & Biophysics, SJ-40, University of
Washington School of Medicine, Seattle, Washington 98195, USA
H.-J . Freund Neurologische Klinik, University of Dusseldorf,
Moorenstrasse 5,4000 Diisseldorf 1, Federal Republic of Germany
A.P. Georgopoulos The Philip Bard Laboratories of Neurophysiology,
Department of Neuroscience, Johns Hopkins University School of
Medicine, 725 N Wolfe Street, Baltimore, Maryland 21205, USA
P.S. Goldman-Rakic Section of Neuroanatomy, Yale University School of
Medicine, C303 SHM, PO Box 3333, New Haven, Connecticut
06510-8001, USA
E.G. Jones Department of Anatomy & Neurobiology, University of
California, California College of Medicine, Irvine, California 92717, USA
J. Kalaska Centre de Recherche en Sciences Neurologiques, FacultC de
Medecine, Universite de Montreal, Case Postale 6128, Succersale A,
MontrCal, Quebec, Canada H3C 357
H.G.J.M. Kuypers Department of Anatomy, University of Cambridge,
Downing Street, Cambridge CB2 3DY, UK
vii
viii Participants
R. Lemon Department of Anatomy, University of Cambridge, Downing
Street, Cambridge CB2 3DY, UK
C.D. Marsden Department of Neurology, Institute of Psychiatry,
De Crespigny Park, Denmark Hill, London SE5 8AF, UK
D.N. Pandya Edith Nourse Rogers Memorial Veterans Hospital, 200 Springs
Road, Bedford, Massachusetts 01730, USA
R.E. Passingham Department of Experimental Psychology, University of
Oxford, South Parks Road, Oxford OX1 3UD, UK
C.G. Phillips Aubrey House, Horton-cum-Studley, Oxford OX9 lBU, UK
R. Porter (Chairman) The John Curtin School of Medical Research, The
Australian National University, GPO Box 334, Canberra City, ACT 2601,
Australia
G. Rizzolatti Istituto di Fisiologia Umana, University of Parma, Via A.
Gramsci 14,43100 Parma, Italy
P.E. Roland Department of Clinical Neurophysiology, Karolinska Hospital,
Box 60 500, S-10401 Stockholm 60, Sweden
Y. Shinoda Department of Physiology, School of Medicine, Tokyo Medical
& Dental University, 1-5-45 Yushima, Bunkyoku, Tokyo 113, Japan
P.L. Strick Department of Physiology & Neurosurgery, Veterans
Administration Medical Center, Research Service (151), 800 Irving
Avenue, Syracuse, New York 13201, USA
J. Tanji Department of Neurophysiology, Brain Research Institute, Tohoku
University School of Medicine, Seiryo-machi 1-1, Sendai 980, Japan
W.T. Thach Department of Anatomy & Neurobiology, Washington
University, School of Medicine, Medical Center, Box 8108,660 South
Euclid Avenue, St Louis, Missouri 63110, USA
M. Wiesendanger Institute of Physiology, University of Fribourg, Rue du
MusCe 5, CH-1700 Fribourg, Switzerland
Wu Chien-Ping Shanghai Brain Research Institute, Chinese Academy of
Sciences, 319 Yo-yang Road, Shanghai, People’s Republic of China
Participants ix
Xi Ming-Chu (Ciba Foundation Bursar) Shanghai Brain Research Institute,
Chinese Academy of Sciences, 319 Yo-yang Road, Shanghai, People’s
Republic of China
Plate 1. 1, 2: regional oxidative metabolism, rCMR02, at rest and during tactile
recognition in a normal young right-handed man. The brain slices are seen from below
(right side of slice is left side of brain). The slices were taken 18 and 5 mm below the
commissural plane and 8, 20, 32 and 46 mm above it. Hippocampus not shown.
lncreases in rCMROz appear bilaterally in parasagittal cerebellum, basal ganglia,
ventral thalamus, anterior insular region, SII, SS, SMA, PM, anterior intraparietal
region (IPA) and prefrontal cortex; increases also appear in left MI and SI. (Plate I
continued overleaf. )