Abortion: medical progress and social implications The Ciba Foundation is an international scientific and educational charity. It was established in 1947 by the Swiss chemical and pharmaceutical company of CIBA Limited-now CIBA-GEIGY Limited. The Foundation operates independently in London under English trust law. The Ciba Foundation exists to promote international cooperation in biological, medical and chemical research. It organizes about eight international multidisciplinary symposia each year on topics that seem ready for discussion by a small group of research workers. The papers and discussions are published in the Ciba Foundation symposium series. The Foundation also holds many shorter meetings (not published), organized by the Foundation itself or by outside scientific organizations. The staff always welcome suggestions for future meetings. The Foundation’s house at 41 Portland Place, London WIN 4BN, provides facilities for all the meetings. Its library, open seven days a week to any graduate in science or medicine, also provides information on scientific meetings throughout the world and answers general enquiries on biomedical and chemical subjects. Scientists from any part of the world may stay in the house during working visits to London. Abortion: medical progress and social implications Ciba Foundation Symposium 115 1985 Pitman London 0C iba Foundation 1985 ISBN 0 272 79815 0 Published in July 1985 by Pitman Publishing Ltd, 128 Long Acre, London WC2E 9AN, UK Distributed in North America by Ciba Pharmaceutical Company (Medical Education Division). P.O. Box 18060, Newark, NJ 07101. USA Suggested series entry for library catalogues: Ciba Foundation symposia Ciba Foundation symposium 115 + viii 284 pages, 15 figures, 52 tables Abortion: medical progress and social implications. -(Ciba Foundation Symposium; 115) 1. Abortion I. Series 363.4’6 RG734 Printed in Great Britain at The Bath Press, Avon Con tents Symposiumo n Abortion: medical progress and social implications, held at the Ciba Foundation, London, 27-29 November 1984 The original suggestion for this symposium came from Dr Malcorn Potts Editors: Ruth Porter (Organizer) and Maeve O’Connor D. T. Baird Introduction I D. B. Paintin Legal abortion in England and Wales 4 Discussion 12 L. AndolSek Abortion services in Slovenia 21 D. A. Grimes Provision of abortion services in the United States 26 General discussion 1 Abortion law and abortion services in Japan and other countries 32 S. Wanjala, N. M. Murugu and J. G. K. Mati Mortality due to abortion at Kenyatta National Hospital, 1974-1983 41 Discussion 48 T. N. Singnomklao Abortion in Thailand and Sweden: health services and short-term consequences 54 Discussion 63 P. Frank Sequelae of induced abortion 67 Discussion 79 D. A. Grimes and K. F. Schulz The comparative safety of second-trimester abortion methods 83 Discussion 96 S. L. Barron Some aspects of late abortion for congenital abnormality 102 Discussion 11 1 General discussion 2 Ethical aspects of abortion 115 V vi CONTENTS W. H. Kitchen, A. L. Rickards, G. W. Ford, M. M. Ryan and J. V. Lissenden Live-born infants of 24 to 28 weeks’ gestation: survival and sequelae at two years of age 122 Discussion 132 Z. MatgjSjfek, Z. Dytrych and V. Schuller Follow-up study of children born to women denied abortion 136 Discussion 147 H. P. David Post-abortion and post-partum psychiatric hospitalization 150 Discussion 161 J. Mattinson The effects of abortion on a marriage 165 Discussion 173 D. T. Baird and Iain T. Cameron Menstrual induction: surgery versus pro- staglandins 178 Discussion 187 E. E. Baulieu Contragestion by antiprogestin: a new approach to human fertility control 192 Discussion 207 R. J. Cook Legal abortion: limits and contributions to human life 211 Discussion 2 18 A. V. Campbell Viability and the moral status of the fetus 228 Discussion 235 J. I. Rosoff Politics and abortion 244 Discussion 253 Final general discussion Providing effective abortion services 256 Effects on society of changes in abortion laws 257 Contragestion 261 M. Potts Medical progress and the social implications of abortion: summing- up 263 Biographies of contributors 269 Index of contributors 275 Subject index 277 Participants A. K. Agarwal (Ciba Foundation Bursar) Division of Endocrinology, Central Drug Research Institute, Chattar Manzil, Post Box No. 173, Lucknow 226001, India L. AndolSek Tozd Univerzitetna Ginekoloika Klinika, Slajmerjeva 3, 61000 Ljubljana, Yugoslavia [contributor unable to attend the symposium] D. T. Baird (Chairman) Department of Obstetrics and Gynaecology, Centre for Reproductive Biology, University of Edinburgh, 37 Chalmers Street, Edinburgh EH3 9EW, UK S. L. Barron Department of Obstetrics and Gynaecology, The Princess Mary Maternity Hospital, Great North Road, Newcastle upon Tyne NE2 3BD, UK E. E. Baulieu Inserm U33, Facult6 de Medecine de BicCtre, Universite de Paris Sud, 78 Avenue du General Leclerc, 94270 BicCtre, France I. T. Cameron Department of Obstetrics and Gynaecology, Centre for Reproductive Biology, University of Edinburgh, 37 Chalmers Street, Edinburgh EH3 9EW, UK A. V. Campbell Department of Christian Ethics and Practical Theology, University of Edinburgh, New College, The Mound, Edinburgh EH12LX, UK F. Cockburn Department of Child Health, University of Glasgow, Royal Hospital for Sick Children, Yorkhill, Glasgow G3, UK R. J. Cook School of Public Health, Columbia University, 60 Haven Avenue B-3, New York, NY 10032, USA H. P. David Transnational Family Research Institute, 8307 Whitman Drive, Bethesda, Maryland 20817, USA P. L. C. Diggory 10 Campden Hill Square, London W8 7LB, UK vii viii PARTICIPANTS G. Dunstan Department of Theology, Queen’s Building, The University, R. Exeter EX4 4QH, UK G. Dworkin Faculty of Law, The University, Southampton SO9 5NH, UK P. I. Frank The Royal College of General Practitioners, Manchester Research Unit, Attitudes to Pregnancy Study, 8 Barlow Moor Road, Manchester M20 OTR, UK D. A. Grimes Centers for Disease Control, Atlanta, Georgia 30033, USA J. P. Hearn Institute of Zoology, Zoological Society of London, Regent’s Park, London NW1 4RY, UK W. H. Kitchen Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria 3052, Australia A. McLaren MRC Mammalian Development Unit, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK Z. MatGjtek Postgraduate Medical Institute, Thomayer Hospital, Prague KRC. Czechoslovakia J. Mattinson Institute of Marital Studies, The Tavistock Centre, 120 Belsize Lane, London NW3 5BA, UK M. Muramatsu Dept of Public Health Demography, Institute of Public Health, 4-61 Shirokanedai, Minato-ku, Tokyo, Japan D. Paintin Department of Obstetrics and Gynaecology, St Mary’s Hospital, London W2 lPG, UK M. Potts Family Health International, Research Triangle Park, North Carolina 27709, USA J. I. Rosoff The Alan Guttmacher Institute, 2010 Massachusetts Avenue N.W., Washington, DC 20036, USA T. N. Singnomklao Faringeplan 42-11, 16-361 Spanga, Sweden S. Wanjala Department of Obstetrics and Gynaecology, University of Nairobi, Kenyatta National Hospital, P.O. Box 30588, Nairobi, Kenya Abortion: medical progress and social implications 0C iba Foundation 1985 Introduction DAVID BAIRD Department of Obstetrics and Gynaecology, Centre for Reproductive Biology, University of Edin- burgh, UK I985 Aborrion: medical progre.s.sa rid sociul implicutions. Piiniun. London (Cibu Foundation Sym- posium 115)p 1-3 What is the purpose of holding a meeting on ‘Abortion: medical progress and social implications’? The need to check the unlimited growth of the world’s population has been accepted by most responsible authorities for about 20 years. In a world with limited resources there will inevitably come a time when the population outstrips the capacity of the world to provide food and other needs. In some parts of the world at the moment we are already seeing what happens when food runs out as a resource. This increasing awareness of the populatiori explosion has led to attempts to disseminate knowledge and exper- tise on various methods of birth control at an unprecedented rate. The successful application of birth control has however been limited, first by the relative ineffectiveness of present methods of family planning but perhaps more importantly by social, religious and political barriers to their widespread use. These limitations in the methods of birth control or family planning dictate that, at least in the foreseeable future, there will probably be a demand for therapeutic abortion. In those countries where contraception is discouraged or is only available on a limited scale, this demand will be reflected in a high incidence of illegal abortion. Even in countries like the United Kingdom, where free family planning services are available within the National Health Service, the number of therapeutic abortions done each year has levelled off at about 175 000 (including non-residents) but shows no sign of dropping. The present methods of contraception are not 100% effective; even if they were, in a highly motivated society mistakes will happen and hence there will be a demand for therapeutic abortion. The introduction of legalized abortion in most countries has almost always been in response to the demand for the individual couple to have control over their own reproductive functions, the so-called ‘fifth freedom’. There are few exceptions to this. In Japan 40 or 50 years ago there was a pressing need to limit population growth and this was achieved by making abortion more easily 1 2 BAIRD available. Most societies make a very clear distinction between abortion-the destruction of a pre-viable fetus-and infanticide, but with advances in neonat- al care the dividing line has become blurred, and it requires constant redraw- ing. I hope that we shall hear more about the ethical implications of this moving target. One reason why most societies and cultures tolerate abortion is that the rate of abortion which occurs naturally in our species is very high: only about one fertilized egg in four results in a viable offspring. The reason for this very high embryonic loss is unknown, although most losses occur very early in pregnan- cy, many before the woman realizes she is pregnant at all. Before the eighth week of pregnancy, that is at up to eight weeks of amenorrhoea or six weeks after conception, over 60% of spontaneous clinical abortions are associated with a very obvious chromosome abnormality in the embryos. Recent studies of very early human embryos fertilized in vitro show that these too have a similarly high percentage of abnormal karyotypes (Angel1 et a1 1983). So it is likely that a significant number of embryos fail to implant in the uterus and hence are lost before the next menstrual period. This high natural wastage should be borne in mind during discussions of the newer methods of contracep- tion involving induction of abortion in early pregnancy. As the gestation period increases, the rate of spontaneous abortion decreases, as does the incidence of abnormal fetuses. Most people are increasingly reluctant to terminate a preg- nancy as it advances, except for very obvious suspected fetal abnormalities. Yet many women who ask for termination of pregnancy in the second trimester do so because their social circumstances are less than optimum and they find it difficult to avail themselves of the medical services. These are the people who on social grounds have the most pressing personal need to limit their further reproduction. For all these reasons it seems likely that even in the best-organized society there will be a continuing demand for abortion. Fortunately, in the last 20 years the methods for inducing therapeutic abor- tion have become simpler and more effective. The most promising develop- ment in recent years has been the possibility of inducing early abortion- so-called menstrual induction-by simple medical means, without resort to surgery. If methods of menstrual induction prove effective they could have wide social and legal implications, because they would not require the interven- tion of skilled medical personnel. But it is unlikely that these methods will ever replace the necessity to perform abortions later in pregnancy, although they should increase the availability of abortion to individual women. It is therefore relevant that at this time we should review what methods of abortion are available, how abortion services are provided in different societies, and what the legal and ethical implications are of the provision of these methods of abortion throughout the world.
Description: