Chitosan for Biomaterials I PDF
Preview Chitosan for Biomaterials I
243 Advances in Polymer Science Editorial Board: A. Abe A.-C. Albertsson K. Dusˇek J. Genzer W.H. de Jeu S. Kobayashi K.-S. Lee L. Leibler T.E. Long I. Manners M. Mo¨ller E.M. Terentjev M. Vicent B. Voit G. Wegner U. Wiesner Advances in Polymer Science Recently Published and Forthcoming Volumes Chitosan for Biomaterials I Polymer Materials Volume Editors: Jayakumar, R., Volume Editors: Lee, K.-S., Kobayashi, S. Prabaharan, M., Muzzarelli, R.A.A. Vol. 231, 2010 Vol. 243, 2011 Polymer Characterization Self Organized Nanostructures Volume Editors: Dusˇek, K., Joanny, J.-F. of Amphiphilic Block Copolymers II Vol. 230, 2010 Volume Editors: Mu¨ller, A.H.E., Borisov, O. Modern Techniques for Nano- Vol. 242, 2011 and Microreactors/-reactions Self Organized Nanostructures Volume Editor: Caruso, F. of Amphiphilic Block Copolymers I Vol. 229, 2010 Volume Editors: Mu¨ller, A.H.E., Borisov, O. Complex Macromolecular Systems II Vol. 241, 2011 Volume Editors: Mu¨ller, A.H.E., Bioactive Surfaces Schmidt, H.-W. Volume Editors: Bo¨rner, H.G., Lutz, J.-F. Vol. 228, 2010 Vol. 240, 2011 Complex Macromolecular Systems I Advanced Rubber Composites Volume Editors: Mu¨ller, A.H.E., Volume Editor: Heinrich, G. Schmidt, H.-W. Vol. 239, 2011 Vol. 227, 2010 Polymer Thermodynamics Shape-Memory Polymers Volume Editors: Enders, S., Wolf, B.A. Volume Editor: Lendlein, A. Vol. 238, 2011 Vol. 226, 2010 Enzymatic Polymerisation Polymer Libraries Volume Editors: Palmans, A.R.A., Heise, A. Volume Editors: Meier, M.A.R., Webster, D.C. Vol. 237, 2010 Vol. 225, 2010 High Solid Dispersion Polymer Membranes/Biomembranes Volume Editor: Cloitre, M. Volume Editors: Meier, W.P., Knoll, W. Vol. 236, 2010 Vol. 224, 2010 Silicon Polymers Organic Electronics Volume Editor: Muzafarov, A. Volume Editors: Meller, G., Grasser, T. Vol. 235, 2011 Vol. 223, 2010 Chemical Design of Responsive Microgels Volume Editors: Pich, A., Richtering, W. Inclusion Polymers Vol. 234, 2010 Volume Editor: Wenz, G. Vol. 222, 2009 Hybrid Latex Particles – Preparation with Emulsion Advanced Computer Simulation Volume Editors: van Herk, A.M., Approaches for Soft Matter Sciences III Landfester, K. Volume Editors: Holm, C., Kremer, K. Vol. 233, 2010 Vol. 221, 2009 Biopolymers Self-Assembled Nanomaterials II Volume Editors: Abe, A., Dusˇek, K., Nanotubes Kobayashi, S. Volume Editor: Shimizu, T. Vol. 232, 2010 Vol. 220, 2008 Chitosan for Biomaterials I Volume Editors: R. Jayakumar M. Prabaharan R.A.A. Muzzarelli With contributions by H. Arami A. Bernkop-Schnu¨rch J.D. Bumgardner M.-C. Chen C.S. Cho M.H. Cho K. Choi Y.J. Choi R. Jayakumar H.L. Jiang K. Kim Y.K. Kim H. Koo I.C. Kwon V.-K. Lakshmanan D.E. Lee Z.-X. Liao F.-L. Mi S.V. Nair I.K. Park F. Sarti S. S¸enel C. P. Sharma K.S. Snima T.A. Sonia Z. Stephen H.-W. Sung O. Veiseh J.Y. Yhee M. Zhang Editors Prof. R. Jayakumar Prof. M. Prabaharan Amrita Center for Nanosciences Department of Chemistry and Molecular Medicine Faculty of Engineering and Technology Amrita Institute of Medical Sciences SRM University and Research Centre Kattankulathur 603 203 Amrita Vishwa Vidyapeetham India Kochi 682 041 Volume Editors Prof. R. Jayakumar Prof. M. Prabaharan Amrita Center for Nanosciences Department of Chemistry and Molecular Medicine Faculty of Engineering and Technology Amrita Institute of Medical Sciences SRM University and Research Centre Kattankulathur 603 203 Amrita Vishwa Vidyapeetham India Kochi 682 041 vi Editorial Board Prof. Kwang-Sup Lee Prof. E.M. Terentjev Department of Advanced Materials Cavendish Laboratory Hannam University Madingley Road 561-6 Jeonmin-Dong Cambridge CB 3 OHE, UK Yuseong-Gu 305-811 Advances in Polymer Sciences Also Available Electronically Advances in Polymer Sciences is included in Springer’s eBook package Chemistry and Materials Science. If a library does not opt for the whole package the book series may be bought on a subscription basis. Also, all back volumes are available electronically. For all customers who have a standing order to the print version of Advances in Polymer Sciences, we offer free access to the electronic volumes of the Series published in the current year via SpringerLink. If you do not have access, you can still view the table of contents of each volume and the abstract of each article by going to the SpringerLink homepage, clicking on “Browse by Online Libraries”, then “Chemical Sciences”, and finally choose Advances in Polymer Science. You will find information about the – Editorial Board – Aims and Scope – Instructions for Authors – Sample Contribution at springer.com using the search function by typing in Advances in Polymer Sciences. Color figures are published in full color in the electronic version on SpringerLink. vii viii Advances in Polymer Sciences Also Available Electronically Aims and Scope The series Advances in Polymer Science presents critical reviews of the present and future trends in polymer and biopolymer science including chemistry, physical chemistry, physics and material science. It is addressed to all scientists at universi- ties and in industry who wish to keep abreast of advances in the topics covered. Review articles for the topical volumes are invited by the volume editors. As a rule, single contributions are also specially commissioned. The editors and pub- lishers will, however, always be pleased to receive suggestions and supplementary information. Papers are accepted for Advances in Polymer Science in English. In references Advances in Polymer Sciences is abbreviated as Adv Polym Sci and is cited as a journal. Special volumes are edited bywell known guest editors who invite reputed authors for the review articles in their volumes. Impact Factor in 2010: 6.723; Section “Polymer Science”: Rank 3 of 79 Preface Chitin and chitosan are known for their excellent biological properties, among which the biocompatibility with human cells, the ordered regeneration of wounded tissues, the immunoenhancing activity, the induction of immediate hemostasis, the radical scavenging activity, and the antimicrobial activity. Recent studies indicate that chitin and chitosan are most versatile in drug and gene delivery, elaborated diagnostics, devices for selective recognition of tumor cells, and surgical aids ranging from anti-adhesion gels to coated sterile stents. The present volumes entitled “Chitosan for Biomaterials I and II” were con- ceived to provide broad and thorough knowledge for highly advanced applications of chitosan and its derivatives in the form of micro- and nanoparticles, nanocom- posites, membranes, and scaffolds. The books consist of 15 chapters written in a manner that meets the expectations of scientists in various disciplines. Chapter 1 deals with the use of chitosan and its derivatives in gene therapy. The effect of several parameters on transfection efficiency of DNA (or gene silencing of siRNA) has been discussed. Moreover, specific ligand and pH-sensitive modifica- tions of chitosan for improvement of cell specificity and transfection efficiency (or gene silencing) are explained. Chapter 2 discusses the recent applications of chitosan nano/microparticles in oral/buccal delivery, stomach-specific drug deliv- ery, intestinal delivery, colon-specific drug delivery, and gene delivery. Chapter 3 is focused on the recent developments of chitosan nanoparticles in bladder, breast, colon, lung, melanoma, prostate, pancreatic, and ovarian cancer therapy. Chapter 4 reviews the design of chitosan-based thiomers and their mechanism of adhesion. In addition, delivery systems comprising of thiolated chitosans and their in vivo performance are discussed. The importance of chitosan in particulate systems for vaccine delivery is emphasized in Chap. 5 according to administration routes, particularly the noninvasive routes involving the oral and pulmonary mucosae. Chapter 6 explains various multifunctional chitosan nanoparticles and their recent applications in tumor diagnosis and therapy. Chapter 7 discusses the current advances and challenges in the synthesis of chitosan-coated iron oxide nanoparti- cles, and their subsequent surface modifications for applications in cancer diagnosis and therapy. Chapter 8 reviews the recent updates of chemical modifications of ix
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