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Chest Pain with Normal Coronary Angiograms: Pathogenesis, Diagnosis and Management PDF

309 Pages·1999·8.157 MB·English
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CHEST PAIN WITH NORMAL CORONARY ANGIOGRAMS: PATHOGENESIS, DIAGNOSIS AND MANAGEMENT Developments in Cardiovascular Medicine 198. Antoine Lafont, Eric Topol (eds.): Arterial Remodeling: A Critical Factor in Restenosis. 1997 ISBN 0-7923-8008-8 199. Michele Mercuri, David D. McPherson, Hisham Bassiouny, Seymour Glagov (eds.):Non-Invasive Imaging ofA therosclerosis ISBN 0-7923-8036-3 200. Walmor C. DeMello, Michiel J. Janse(eds.): Heart Cell Communication in Health and Disease ISBN 0-7923-8052-5 201. P.E. Vardas (ed.): Cardiac Arrhythmias Pacing and Electrophysiology. The Expert View. 1998 ISBN 0-7923-4908-3 202. E.E. van der Wall, P.K. Blanksma, M.G. Niemeyer, W. Vaalburg and H.J.G.M. Crijns (eds.) Advanced Imaging in Coronary Artery Disease, PET, SPECT, MRI. I VUS, EBCT. 1998 ISBN 0-7923-5083-9 203. R.L. Wilensky (ed.) Unstable Coronary Artery Syndromes, Pathophysiology, Diagnosis and Treatment. 1998. ISBN 0-7923-8201-3 204. J.H.C. 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Juan Carlos Kaski (ed.): Chest Pain with Normal Coronary Angiograms: Pathogenesis, DiagnosiS and Management. 1999. ISBN: 0-7923-8421-0 Previous volumes are still available KLUWER ACADEMIC PUBLISHERS - DORDRECHTIBOSTONILONDON Chest Pain with Normal Coronary Angiograms: Pathogenesis, Diagnosis and Management edited by Juan Carlos Kaski MD, MRCP, FACC,FESC BHF Sugden Reader in Clinical Cardiology and Consultant Cardiologist, Head ofC oronary Artery Disease Research Group, St George 's Hospital Medical School, London, UK ~. " Springer Science+Business Media, LLC Library of Congress Cataloging-in-Publication Data ISBN 978-1-4613-7360-5 ISBN 978-1-4615-5181-2 (eBook) DOI 10.1007/978-1-4615-5181-2 Copyright © 1999 Springer Science+Business Media New York Originally published by Kluwer Academic Publishers in 1999 Softcover reorint of the hardcover 1 st edition 1999 AII rights reserved. No part ofthis publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, mechanical, photo copying, recording, or otherwise, without the prior written permission of the publisher, Springer Science+Business Media, LLC Printed on acid-free paper. Table of Contents List of Contributors ix Foreword xiii Preface xvii Chapters 1. Cardiac syndrome X and microvascular angina 1 Juan Carlos Kaski 2. Chest pain with normal coronary arteries: psychological aspects 13 Steve G. Potts and Christopher Bass 3. Esophageal chest pain 33 John S. de Cae stecker 4. Esophageal abnormalities and "Linked -Angina" in syndrome X 49 Anoop Chauhan 5. Abnormal pain processing in syndrome X 61 Ole Fmbert, Lars Arendt-Nielsen and Jens Peder Bagger 6. Insights into the pathophysiology of syndrome X obtained using positron emission tomography (PET) 69 Stuart D. Rosen and Paolo G. Camici 7. Myocardial metabolism in cardiac syndrome X 81 Jens Peder Bagger 8. Endothelial dysfunction in cardiac syndrome X (microvascular 91 angina) Kensuke Egashira, Masahiro Mohri and Akira Takeshita 9. Endothelin: an important mediator in the pathophysiology of syndrome X 101 Ian D. Cox and Juan Carlos Kaski vi 10. Estrogen deficiency and syndrome X 115 Peter Collins It. Alternative mechanisms for myocardial ischemia in syndrome X -New diagnostic markers 123 Filippo Crea, Antonio Buffon, Achille Gaspardone and Gaetano Lanza 12. Increased plasma membrane ion-leakage: A new hypothesis for chest pain and normal coronary arteriograms 135 Anders Walden strom and Gunnar Ronquist 13. A possible cell membrane defect in chronic fatigue syndrome and syndrome X 143 Walter S. Watson, Abhijit Chaudhuri, Georgina T. McCreath and Peter O. Behan 14. The changing concept of syndrome X 151 Attilio Maseri, Gaetano Antonio Lanza and Antonino Buffon 15. Assessment of coronary blood flow reserve - Techniques and limitations 159 Antonio L' Abbate 16. The role of echocardiography in diagnosis and management of cardiac syndrome X 171 Petros Nihoyannopoulos 17. Imaging in microvascular angina - what's new? 181 Ann Tweddel 18. Assessment of quality of life in patients with syndrome X 187 Felipe Atienza and Jose A. de Velasco 19. Treatment of patients with angina and normal coronary arteriograms 195 Giuseppe M.C. Rosano, Gabriele Fragasso and Sergio L. Chierchia 20. Management strategies for chest pain in patients with normal coronary angiograms 203 Richard O. Cannon III 21. Abnormal autonomic nervous control of the cardiovascular system 211 Giuseppe M.C. Rosano, Gabriele Fragasso, Sergio L. Chierchia vii 22. The metabolic syndrome 221 Francisco Leyva and John C. Stevenson 23. Two syndromes X 243 Andrew Henderson 24. Hyperlipidemia and endothelial vasodilator dysfunction: The pathogenetic link to myocardial ischemia 251 Andreas M. Zeiher 25. Microvascular dysfunction in patients with systemic hypertension without left ventricular hypertrophy: The role of nitric oxide 259 Julio A. Panza 26. Microvascular angina and hypertensive left ventricular hypertrophy 269 Wolfgang Motz and Sibylle Scheler 27. Myocardial ischemia in hypertrophic cardiomyopathy: Clinical assessment and role in natural history 281 Perry M. Elliott 28. Microvascular endothelial dysfunction after heart transplantation 293 Giuseppe Vassalli and Augusto Gallino Index 305 List of Contributors Lars Arendt-Nielsen, MsSc Laboratory for Experimental Pain Research, University of Aalborg, Aalborg, Denmark Filipe Atienza, MD Cardiology Department, Hospital General Universitario, Valencia, Spain Jens Peder Bagger, MD Division of Cardiology, Imperial College School of Medicine, Hammersmith Hospital, London, UK Christopher Bass, MA, MD, FRCPsych Consultant in Liaison Psychiatry, Department of Psychological Medicine, John Radcliffe Hospital, Oxford, UK Peter O. Behan, MBChB, MD, DSc, FACP, FRCP(Glas, Lond, Ire) University Department of Neurology, Institute of Neurological Sciences, Southern General Hospital NHS Trust, Glasgow, Scotland, UK Antonino Buffon, MD Institute of Cardiology, Universita Cattolica del Sacro Cuore, Rome, Italy Paolo G. Camici, MD, FRCP FESC, FACC MRC Clinical Sciences Centre, RPMS, Hammersmith Hospital, London, UK Richard O. Cannon III, MD Cardiology Branch, NHLBI, National Institutes of Health, Bethesda, Maryland, USA Ahhijit Chaudhuri, DM, MD, MRCP(UK) University Department of Neurology, Institute of Neurological Sciences, Southern General Hospital NHS Trust, Glasgow, Scotland, UK Anoop Chauhan, MD, MRCP Consultant Cardiologist, Regional Cardiac Unit, Victoria Hospital, Blackpool, UK Sergio L. Chierchia, MD, FACC, FESC Professor of Cardiology, Department of Cardiology, Istituto H San Raffaele, Milano and Roma, Italy Peter Collins, MA, MD(Cantah), FRCP, FESC, FACC National Heart and Lung Institute, Imperial College School of Medicine, London, UK x Ian D. Cox, MA, MRCP Coronary Artery Disease Research Group, Department of Cardiological Sciences, St George's Hospital Medical School, London, UK Filippo Crea, MD, FACC, FESC Senior Lecturer in Cardiology, Institute of Cardiology, Universita Cattolica del Sacro Cuore, Rome, Italy John S. de Caestecker, MD, FRCP, FRCP(E) Consultant Gastroenterologist, The Glenfield Hospital and Honorary Senior Lecturer, Division of Gastroenterology, University of Leicester Medical School, Leicester, UK Kensuke Egashira, MD, PhD Research Institute of Angiocardiology and Cardiovascular Clinic, Kyushu University Faculty of Medicine, Fukuoka, Japan Perry M. Elliott, MRCP Department of Cardiological Sciences, St George's Hospital Medical School, London, UK Gabriele Fragasso, MD Senior Lecturer, Department of Cardiology, Istituto H San Raffaele, Milano and Roma, Italy Ole Frobert, MD Department of Cardiology, Skejby Section, Aarhus University Hospital, Aarhus, Denmark Augusto Gallino, MD, FACC, FESC Specialista FMH Medicina Interna, Cardiologia E Angiologia, Primario Ospedale San Giovanni, Bellinzona, Switzerland Achille Gaspardone, MD, FESC Cattedra di Cardiochirurgia, Universita Tor Vergata, Rome, Italy Andrew Henderson, FRCP, FESC Department of Cardiology, University of Wales College of Medicine, Cardiff, Wales, UK Juan Carlos Kaski, MD, MRCP, FESC, FACC Reader in Clinical Cardiology and Consultant Cardiologist, Head of Coronary Artery Disease Research Group, St George's Hospital Medical School, London, UK Antonio L'A bbate, MD CNR Clinical Physiology Institute, via Savi 8, Pisa, Italy xi Gaetano Antonio Lanza, MD, FESC Institute of Cardiology, Universita Cattolica del Sacro Cuore, Rome, Italy Francisco Leyva, MD, ChB, BSc (Hons), MRCP Department of Cardiac Medicine, Royal Brompton Hospital, London, UK Georgina T. McCreath, MBChB, DMRD, FRCR, FRCP(Glas) Department of Radiology, Southern General Hospital NHS Trust, Glasgow, Scotland, UK Attilio Maseri, MD, FACC, FESC, FRCP Professor of Cardiology, Director Institute of Cardiology, Universita Cattolica del Sacro Cuore, Rome, Italy Masahiro Mohri MD, PhD Research Institute of Angiocardiology and Cardiovascular Clinic, Kyushu University Faculty of Medicine, Fukuoka, Japan Wolfgang Motz, MD, PhD, Professor of Medicine Herz-und Diabeteszentrum Mecklenburg-Vorpommern, Klinik fUr Kardiologie, Karlsburg, Germany Petros Nihoyannopoulos, MD, FACC, FESC Senior Lecturer and Consultant Cardiologist, Cardiology Division, Imperial College School of Medicine, National Heart & Lung Institute, Hammersmith Hospital, London, UK Julio A. Panza, MD Vascular Physiology Laboratory, Section on Echocardiography, Cardiology Branch, National Heart, Lung & Blood Institute, National Institutes of Health, Bethesda, USA Stephen Potts, MA, BM, BCh, MRCPsych Department of Psychological Medicine, Royal Infirmary (Edinburgh), Edinburgh, Scotland, UK Gunnar Ronquist, MD, PhD Department of Clinical Chemistry, University Hospital, Uppsala:, Sweden Giuseppe M.e. Rosano, MD, FACC Senior Lecturer, Department of Cardiology, Istituto H San Raffaele, Milano and Roma, Italy Stuart D. Rosen, MA, MD, MRCP, FESC, FACC Honorary Consultant Cardiologist, MRC Cyclotron Unit, Imperial College. School of Medicine, Hammersmith Hospital, London, UK

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