Vol. 40, 1994 Chemotherapy International Journal of Experimental and Clinical Chemotherapy Founded 1959 as ‘Chemotherapia’ Editor Editorial Board H. Schonfeld, T. Bergan, Oslo Grenzach-Wyhlen W.P. Boger, Wayne, Pa. V. Kréméry, Jr., Bratislava A. Polak, Basel P. Preziosi, Rome K. Shimizu, Tokyo R.W. Sidwell, Logan, Utah M. Tattersall, Sydney W.H. Traub, Homburg/Saar KARGER Contents Vol. 40, 1994 Modulation of EGF Receptor and CD15 (Lewis*) 51 No. 1 Antigen on the Cell Surface of Breast Carcinoma Pharmacology Cell Lines Induced by Cytokines, Retinoic Acid, 12-O-Tetradecanoylphorbol 13-Acetate and Simulation of Human Plasma Levels of B-Lac- 1,25(OH)2-Vitamin D3 tams in Mice by Multiple Dosing and the Rela- Sedlak, J.; Speiser, P.; Hunakova, L.; Duraj, J.; tionship between the Therapeutic Efficacy and Chorvath, B. Pharmacodynamic Parameters Clinical Reports Hatano, K.; Wakai, Y.; Watanabe, Y.; Mine, Y. Lipid Peroxides in the Polychemotherapy of Intrapericardial Mitomycin C for the Manage- 57 Cancer Patients ment of Malignant Pericardial Effusion Second- Look, M.P.; Musch, E. ary to Gastric Cancer: Case Report and Review Kohnoe, S.; Maehara, Y.; Takahashi, I.; Saito, A.; Microbiology Okada, Y.; Sugimachi, K. Increased Resistance of Encapsulated Bacteroides 16 Antibiotic Therapy for Typhoid Fever 61 fragilis to Clindamycin Ruanguan, W.; Kunming, Y.; Qiong, S. Brook, I.; Gillmore, J.D. Single-Dose Antibiotic Prophylaxis in Maxillo- 65 Activity of Twenty-One Antimicrobial Agents facial Surgery Including /-Ofloxacin against Quinolone-Sensi- Hotz, G.; Novotny-Lenhard, J.; Kinzig, M.; Soergel, F. tive and -Resistant, and Methicillin-Sensitive Aureobasidium mansoni Meningitis in a Leuke- 70 and -Resistant Staphylococcus aureus mia Patient Successfully Treated with Amphoter- Peterson, L.R.; Cooper, I.; Willard, K.E.; Fasching, C.E.; icin B Sinn, L.M.; Shanholtzer, C.J.; Gerding, D.N. Krémeéry, V., Jr.; Spanik, S.; DaniSovitova, A.; Susceptibility of Methicillin-Resistant Staphylo- Jesenska, Z.; Blahova, M. coccus aureus to Minocycline and Other Anti- microbials Book Review 2 Qadri, $.M.H.; Halim, M.; Ueno, Y.; Saldin, H. Postantibiotic Effect, and Postantibiotic Effect of Subinhibitory Concentrations, of Sparfloxacin on Gram-Negative Bacteria Odenholt-Tornqvist, I.; Bengtsson, S. SOTSSSHSHSHTOSSSSSOSSOSSESSOHEEEHESOOSEESOEESOSEESSEEEEES Experimental Chemotherapy The in vitro Effects of Ceftibuten on the Host 37 Defense Mechanism Braga, P.C.; Piatti, G.; Dal Sasso, M.; Maci, S.; Blasi, F. Influenza Virus-Inhibitory Effects of Intraperito- 42 neally and Aerosol-Administered SP-303, a Plant Flavonoid Sidwell, R.W.; Huffmann, J.H.; Moscon, B.J.; Warren, R.P. No. 2 Clinical Reports Effect of Fluconazole Prophylaxis onn Fever and Microbiology Use of Amphotericin in Neutropenic Cancer Morphological Alterations of Staphylococcus Patients aureus and Streptococcus pyogenes Exposed to Chandrasekar, P.H.; Gatny, C.M.; Bone Marrow Cefdinir, a New Oral Broad-Spectrum Cephalo- Transplantation Team sporin Carboplatin and Etoposide as Outpatient Treat- Hatano, K.; Nishino, T. ment of Advanced Non-Small-Cell Lung Cancer In vitro Activity ofC efdinir (FK482) and Ten Pronzato, P.; Landucci, M.; Vaira, F.; Vigani, A.; Other Antibiotics against Gram-Positive and Bertelli, G. Gram-Negative Bacteria Isolated from Adult and Pediatric Patients Sultan, T.; Baltch, A.L.; Smith, R.P.; Ritz, W. eeeeeeceeeeeceeeeeeeeeeseeeeseeeeseseseeseeseseeeeseeeeeee No.3 Inv itro Susceptibility of FungalI solates of cl ini- 92 cally Important Specimens to Itraconazole, Flu- SSSHSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSESESESCSCOS Pharmacology conazole and Amphotericin B Dermoumi, H. Individualization of5: -F luorocyttoo sine Therapy Enhanced Susceptibility of Escherichia coli Pre- 99 Petersen, D.; Demertzis, S.; Freund, M.; Schumann, G.; Oellerich, M. treated with RP7293 to Leukocyte Activity: Comparison with Other Antimicrobial Agents Serum Levels ofF lurithromycin Ethylsuccinate 157 Pérez, P.; Herrera, I.; Martin, M.; Martinez, P.; in Healthy Volunteers Gomez- Lus, M.L. Cocuzza, C.E.; Mattina, R.; Lanzafame, A.; Romoli, L.; Lepore, A.M. In vitro Activity ofR ufloxacin against Listeria monocytogenes, Legionella pneumophila, and Micrebislogy Chlamydia trachomatis Furneri, P.M.; Bazzano, M.; Campo, L.; Cesana, M.; Inv itro Antibacterial Activity of FK037,aNew 161 Tempera, G. Parenteral Broad-Spectrum Cephalosporin, SOCHHSSHHSSHSSSOSSSSSHSSHSOSSOOOSSSOSESOHSHSSSSSHSESOSEEES against Recent Clinical Isolates in the Fields of Experimental Chemotherapy Obstetrics and Gynecology Antitumor, Anti-Inflammatory and Analgesic 109 Mikamo, H.; Izumi, K.; Ito, K.; Katoh, N.; Watanabe, K.; Ueno, K.; Tamaya, T. Property of Embelin, a Plant Product Chitra, M.; Sukumar, E.; Suja, V.; Shyamala Devi, C.S. Inv itro andi in vivo Antibacterial Activities of FK037, a New Parenteral Cephalosporin Antibiotics Alter Interactions of Staphylococcus 114 Nishino, T.; Otsuki, M.; Hatano, K.; Nishihara, Y. aureus with Collagenous Substrata Butcher, W.G.; Close, J.; Krajewska-Pietrasik, D.; Comparative Activity of B-- Lactam Antibiotics Switalski, L.M. against ‘Intrinsically’ Ticarcillin-Resistant Strains of Pseudomonas aeruginosa Influence of Membrane feo mposition of Various — 124 Parasites on the Inhibitory Activity of a Series of Bert, F.; Bruneau, B.; Lambert-Zechovsky, N.; Branger, C. Bipyridyl Analogues SOCOSOHSSSHSSSSSSSSSSSSHSSSSSSSSSSSOSSSESSSS OHSOH SSESOEO®S Seydel, J.K.; van der Goot, H.; Timmerman, H. Experimental Chemotherapy Enhancement of Doxorubicin-Induced Cyto- 188 toxicity by Hyperthermia in Ehrlich Ascites Cells Al-Shabanah, O.A.; Osman, A.M.; Al-Harbi, M.M.; Al-Gharably, N.M.; Al-Bekairi, A.M. Relationships between Structure and Antiretrovi- 195 ral Activity of Thiosemicarbazone Derivatives Teitz, Y.; Barko, N.; Abramoff, M.; Ronen, D. SCOHSOSSSSSSSOSSSSSHSSSSSHHSSSHSHSSSSOSESSOSOSESESESOOEE®S Anti-HIV Activity of Dideoxynucleosides, Fos- 201 Experimental Chemotherapy carnet and Fusidic Acid Is Potentiated by Human Leukocyte Interferon in Blood-Derived Therapeutic Effects of Roxithromycin and 252 Macrophages Azithromycin in Experimental Murine Brucello- Degré, M.; Beck, S. sis Lang, R.; Shasha, B.; Ifrach, N.; Tinman, S.; Magnetic Resonance Imaging in Children Rubinstein, E. Receiving Quinolones: No Evidence of Quino- lone-Induced Arthropathy. A Multicenter Survey Phagocyte Transport as Mechanism for Enhanced Therapeutic Activity of Liposomal DaniSovitova, A.; Brezina, M.; Belan, S.; Kayserova, H.; Kaiserova, E.; HruSkovié, I.; Orosova, K.; Amphotericin B Dluholucky, S.; Galova, K.; Mathéova, E.; Marinova, I.; Mehta, R.T.; McQueen, T.J.; Keyhani, A.; Kréméry, V., Jr. Lépez-Berestein, G. Effect of Antibiotics on Bordetella pertussis Intrinsic Overexpression of Two Different Mech- 265 Adhering Activity: Hypothesis Regarding Mecha- anisms of Resistance to Chemotherapy (P-Glyco- nism of Action protein and GST-z) in Human Endometrial Scaglione, F.; Demartini, G.; Dugnani, S.; Ferrara, F.; Carcinoma Maccarinelli, G.; Cocuzza, C.; Fraschini, F. Schneider, J.; Efferth, T.; Rodriguez-Escudero, F.J.; Volm, M. Plant Lectins as Inhibitors of Tumour Growth 272 @eeceeeseseseseeeeoeseseeeeeeeseeeeeoaeeeecesaorneeeseeeeseseee and Modulators of Host Immune Response No.4 Ganguly, C.; Das, S. SSCSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSHSSSSESSESSESCSSCOSESES Pharmacology Clinical Reports Pharmacokinetics and Penetration into Tissue 71 Postoperative Chemotherapy for Gastric Cancer 279 Fluid of Cefotaxime in Bovines in the Elderly Rule, R.; Buschiazzo, H.; Rubio, M.; Quiroga, G.; Maehara, Y.; Yamamoto, M.; Endo, K.; Baba, H.; de Buschiazzo, P. Kusumoto, H.; Sugimachi, K. Pharmacokinetic Profile of Methotrexate and 227 Rhodotorula spp. Fungemia in an Immunocom- 5-Fluorouracil in Normal and Bilharzial-Infested promised Boy after Neurosurgery Successfully Mice Treated with Miconazole and 5-Flucytosine: Osman, A.-M.M.,; Saad, S.F.; Saad, S.Y.; Case Report and Review of the Literature El-Aaser, A.-B.A.; El-Merzabani, M.M. Marinova, I.; Szabadosova, V.; Brandeburova, O.; SOOOSSSOSOOSSSOSSESSSOSOSOSSSOEEEO SHOOSSSSHSEHSSESOEOEOES Kréméry, V., Jr. Microbiology SOOSSHSOSSSSSSSSOSSSSOSHSSSSSSOHSSSOSSOHSSSOOOSESOOOSESES Book Review 290 Post-Antibiotic Effects of Cefdinir on Escherichia 232 Announcement 292 coli, Klebsiella pneumoniae, Staphylococcus aureus and Streptococcus pyogenes Howard, B.M.A.; Pinney, R.J.; Smith, J.T. In vitro Sensitivity of Medically Significant Fusarium Species to Various Antimycotics Sekhon, A.S.; Padhye, A.A.; Garg, A.K.; Ahmad, H.; Moledina, N. Multicenter Evaluation of ATB Fungus: A Stan- dardized Micromethod for Yeast Susceptibility Testing Quindés, G.; Salesa, R.; Carrillo-Mufioz, A.J.; Lipperheide, V.; Jaudenes, L.; San Millan, R.; Torres-Rodriguez, J.M.; Ponton, J. Contents SSSOSSSSSEHSSSSSSSSSESSSSSSSSSSSEHSOSSSSSESESESESSSEESESEE No.5 Clinical Reports SCOHSSSSSSSSSSHSSSSHSSSSSOSSOOOSSHTSESSSOSSESESESSESOSEEEOS Microbiology Undifferentiated C arcinoma of the Sinuses and ; 357 Cranial Basis Successfully Treated with Radio- Comparative in vitro Activity of Fleroxacin, Two 293 chemotherapy. A Case Report Other Quinolones and Three Broad-Spectrum Chandrasekaran, S.; Baba, A.A.; Othman, N.; Beta-Lactams Using the E-Test Jayakumar, C.R. Sobottka, I.; Neumann, S.; Laufs, R. Study on Treatment of Bacterial Vaginosis with Antibiotic Resistance Patterns of Streptococcus 299 Oral Administration of Metronidazole or pneumoniae, Haemophilus influenzae and Cefdinir Moraxella catarrhalis: A Prospective Study in Mikamo, H.; Izumi, K.; Ito, K.; Katoh, N.; Murcia, Spain, 1983-1992 Watanabe, K.; Ueno, K.; Tamaya, T. Gomez, J.; Ruiz-Gémez, J.; Hernandez-Cardona, J.L.; Nujiez, M.L.; Canteras, M.; Valdés, M. Effects of Subinhibitory Concentrations of Seven 304 Macrolides and Four Fluoroquinolones on Adhe- No. 6 sion of Staphylococcus aureus to Human Mucosal SOSSSSSSSHSSSSSSSSSSSSOSSOSSSSSSSSSOSSSSSSSSSOSSSOSEESESS Pharmacology Cells Braga, P.C. Hemodialysis Removal of Norfloxacin 369 In vitro Activity of Cefpirome against Beta- Lau, A.H.; Tang, I.; Fitzloff, J.; Jain, R. Lactamase-Inducible and Stably Derepressed Microbiology Enterobacteriaceae Bonfiglio, G.; Stefani, S.; Nicoletti, G. Agar Disk Diffusion (Bauer-Kirby) Tests with Various Fastidious and Nonfastidious Reference In vitro Activity of Two New Oral Cephalospo- 317 (ATCC) Strains: Comparison of Several Agar rins, Cefixime and Cefdinir (CI 983), on Human Media Peripheral Mononuclear and Polymorphonuclear Leukocyte Functions Traub, W.H.; Leonhard, B. Fietta, A.; Merlini, C.; Gialdroni Grassi, G. Antibacterial Activity of Cefepime in vitro 384 Liu, Y.-C.; Huang, W.-K.; Cheng, D.-L. Experimental Chemotherapy Comparative Antimicrobial Activity of FK037, 391 Correlation between the in vitro and in vivo 324 Cefpirome, Ceftazidime and Cefepime against Effects of Fourteen Beta-Lactam Compounds in Aminoglycoside-Sensitive and Aminoglycoside- Mice with Systemic Infection Resistant Pseudomonas aeruginosa and Pseudo- Tsuji, A.; Kaneko, Y.; Yamaguchi, K.; Goto, S. monas spp. Enhanced Chemiluminescence Response of Poly- 333 Baltch, A.L.; Smith, R.P.; Ritz, W. morphonuclear Leukocytes by New Quinolone Susceptibility of Clinically Significant Haemo- Antimicrobials Dhilus influenzae Strains to Oral Antimicrobial Kubo, S.; Matsumoto, T.; Takahashi, K.; Haraoka, M.; Agents Used in Saudi Arabia Tanaka, M.; Sakumoto, M.; Sakamoto, Y.; Shibl, A.M.; Gaillot, O. Kumazawa, J. SOOOHSEHOSHSSSH SSSSOSSSOSHSSSSSHSSSHSSSESOSSSESESSOOOSESSE S Anticarcinogenic Effect of Commiphora molmol 337 Experimental Chemotherapy on Solid Tumors Induced by Ehrlich Carcinoma Comparative Study of the Effects of Cefodizime 404 Cells in Mice and HBW 538 in Potentiating the Production of Al-Harbi, M.M.; Qureshi, S.; Raza, M.; Ahmed, M.M.; Reactive Oxygen Species by Human Polymor- Giangreco, A.B.; Shah, A.H. phonuclear Leukocytes In vitro Effect of 5-Fluorouracil, Verapamil and Ono, Y.; Kunii, O.; Ohyatsu, I.; Tokumura, Y.; Hyperthermia on the Human Pancreatic Adeno- Miyashita, T.; Aoki, M.; Sugiyama, H.; Nishiya, H.; carcinoma Cell Line ASPC-1 Miyashita, H.; Goldstein, E. Shchepotin, I.B.; Buras, R.R.; Nauta, R.J.; Shabahang, M.; Soldatenkov, V.A.; Evans, S.R.T. SOOOSHSSOSSSSSHSSSSHSSSSSOHSSSSSSOSESSOSSOOESESESESEEEESE Levofloxacin, an Optical Isomer of Ofloxacin, 412 Clinical Reports Has Attenuated Epileptogenic Activity in Mice and Inhibitory Potency in GABA Receptor Teicoplanin plus Pefloxacine versus Teicoplanin 431 Binding plus Netilmicin in Empiric Therapy of Febrile Akahane, K.; Tsutomi, Y.; Kimura, Y.; Kitano, Y. Patients with Cancer and Neutropenia. A Ran- domized Study of Two Once Daily Regimens in Enhancement of Chemosensitivity of Quiescent Patients with Previously Inserted Catheters Cell Populations in Murine Solid Tumors Using Studena, M.; Hlavaéova, E.; Hel’pianska, L.; Nicotinamide Vonkomerova A.; Lacka, J.; Studena, V.; Kukuckova, E.; Masunaga, S.; Ono, K.; Akuta, K.; Akaboshi, M.; Kollar, T.; Pichiia, P.; Salek, T.; Sufliarsky, J.; Trupl, J.; Kawai, K.; Takagaki, M.; Abe, M. Kréméry, V., Jr. Alterations in Erythrocyte Membrane Structure 3 Antimicrobial Prophylaxis with Ceftriaxone in 435 of Breast Cancer Patients Treated with CMF - Renal Transplantation. Prospective Study of 170 A Lipid Profile Patients Subramaniam, S.; Subramaniam, S.; Jagadeesan, M.; Capocasale, E.; Mazzoni, M.P.; Tondo, S.; D’Errico, G. Shyamala Devi, C.S. Author Index Vol. 40, 1994 441 Subject Index Vol. 40, 1994 443 Use of Ciprofloxacin in the Treatment of Chronic Otitis and Sinusitis and Malignant External Otitis Ce cccccccccccccccccccccccccccccccoece ec ccccccccccccccccccccccccccccccccces S. Karger Drug Dosage All rights reserved. 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