Table Of Content

Chem.-Biol. Interactions, 80 (1991) 349—351 Elsevier Scientific Publishers Ireland Ltd. CHEMICO-BIOLOGICAL INTERACTIONS SUBJECT INDEX VOLUME 80 (1991) Autoxidation, hydroquinone, benzoquinone, Cytotoxic and mutagenic potentials, pregnane superoxide dismutase, kinetics, induction derivative, «,@-unsaturated carbonyl, period, 159 Michael addition, mechanism of action, DNA, RNA and protein biosynthesis, cell B16 melanoma, strychnopentamine, dimeric cycle specificity, 43 indole alkaloid, non-cancer fibroblasts, cytotoxicity, 203 Dibenzanthracenes, metabolism, bis-dihydro- 1,2,4-Benzenetriol, heme, hydroquinone, oxy- diols, 261 gen radicals, thiobarbituric acid reactive 1,3-Dichloropropanol, mechanisms for muta- products, 339 genicity and genotoxicity, epichlorohydrin Benzoquinone, hydroquinone, superoxide formation, 73 dismutase, autoxidation, kinetics, induction Dimeric indole alkaloid, strychnopentamine, period, 159 B16 melanoma, non-cancer fibroblasts, bis-Dihydrodiols, dibenzanthracenes, metabo- cytotoxicity, 203 lism, 261 Diol-epoxides, **P-postlabeling, DNA adducts, Butadiene, epoxybutene, hemoglobin adducts, V79 cell, polycyclic aromatic hydrocarbons, mercapturic acids, rats, 291 177 Butylated hydroxyanisole, carcinogenicity, DNA, RNA and protein _ biosynthesis, mechanism, reactive oxygen species, DNA pregnane derivative, a,6-unsaturated car- adducts, 109 bonyl, Michael addition, mechanism of action, cytotoxic and mutagenic potentials, Carcinogenesis, hydrazine oxidation, hydroxy- cell cycle specificity, 43 2’-deoxyguanine, hydroxy] radical, 57 DNA-binding protein, heavy metal, Carcinogenicity, butylated hydroxyanisole, metallothionein, metal responsive element, mechanism, reactive oxygen species, DNA mobility shift assay, 145 adducts, 109 DNA adduct, N7-(2-hydroxyethyl)guanine, Carcinogenicity, singlet oxygen, photosen- ethylene oxide, HPLC with electrochemical sitization, genotoxicity, DNA damage, detection, 281 mutagenicity, 239 DNA adducts, butylated hydroxyanisole, car- Cell cycle specificity, pregnane derivative, a,(- cinogenicity, mechanism, reactive oxygen unsaturated carbonyl, Michael addition, species, 109 mechanism of action, DNA, RNA and pro- DNA adducts, postlabeling, 1,N®-etheno- tein biosynthesis, cytotoxic and mutagenic adenine, 3,N4-ethenocytosine, 1,N2- potentials, 43 ethenoguanine, T4 polynucelotide kinase, Cultured cells, oxidative stress, cytoskeleton, 99 DNA adducts, °*P-postlabeling, V79 cell, diol- 217 Cytoskeleton, oxidative stress, cultured cells, epoxides, polycyclic aromatic hydrocar- 217 bons, 177 Cytotoxicity, quinones, hepatocytes, redox DNA damage, singlet oxygen, photosensitiza- cycling, oxidative stress, 1 tion, genotoxicity, mutagenicity, car- Cytotoxicity, strychnopentamine, dimeric in- cinogenicity, 239 dole alkaloid, B16 melanoma, non-cancer DT-Diaphorase, indole-3-carbinol (acid conden- fibroblasts, 203 sation products of), hepatocytes, P-450, 303 350 Effect of thiols, nitropropane, nitronate 8-Hydroxy-2’-deoxyguanine, hydrazine oxida- decomposition, equilibrium, 187 tion, carcinogenesis, hydroxyl radical, 57 8-Hydroxy-2’-deoxyguanosine, English sole, English sole, nitrofurantoin, oxidative DNA damage, 8-hydroxy-2’-deoxyguanosine, nitrofurantoin, oxidative DNA damage, 317 317 Epichlorohydrin formation, 1,3-dichloropro- N7-(2-Hydroxyethyl)guanine, DNA adduct, panol, mechanisms for mutagenicity and ethylene oxide, HPLC with electrochemical genotoxicity, 73 detection, 281 Epoxybutene, butadiene, nemoglobin adducts, Hydroxyl radical, hydrazine oxidation, mercapturic acids, rats, 291 8-hydroxy-2’-deoxyguanine, carcinogene- Equilibrium, nitropropane, nitronate decom- sis, 57 position, effect of thiols, 187 1,N®-Ethenoadenine, _postlabeling, 3,N4- Indole-3-carbinol (acid condensation products ethenocytosine, 1,N?-ethenoguanine, DNA of), hepatocytes, P-450, DT-diaphorase, 303 adducts, T4 polynucelotide kinase, 99 Induction period, hydroquinone, benzo- 3,N4-Ethenocytosine, postlabeling, 1,N°- quinone, superoxide dismutase, autoxida- ethenoadenine, 1,N?-ethenoguanine, DNA tion, kinetics, 159 adducts, T4 polynucelotide kinase, 99 1,N?-Ethenoguanine, _postlabeling, 1,N®- Kinetics, hydroquinone, benzoquinone, super- ethenoadenine, 3,N‘4-ethenocytosine, DNA oxide dismutase, autoxidation, induction adducts, T4 polynucelotide kinase, 99 period, 159 Ethylene oxide, N7-(2-hydroxyethyl)guanine, DNA adduct, HPLC with electrochemical Liver and intestinal microsomes, oxidants, detection, 281 peroxidation, 135 Genotoxicity, singlet oxygen, photosensitiza- Mechanism, butylated hydroxyanisole, car- tion, DNA damage, mutagenicity, carcinogenicity, reactive oxygen species, DNA cinogenicity, 239 adducts, 109 Glutathione, mice, oral GSH supplementation, Mechanisms for mutagenicity and genotoxi- tissue GSH, 89 city, 1,3-dichloropropanol, epichlorohydrin formation, 73 Heavy metal, metallothionein, metal respon- Mechanism of action, pregnane derivative, a,8- sive element, DNA-binding protein, mobili- unsaturated carbonyl, Michael addition, ty shift assay, 145 DNA, RNA and protein biosynthesis, Heme, hydroquinone, 1,2,4-benzenetriol, oxy- cytotoxic and mutagenic potentials, cell gen radicals, thiobarbituric acid reactive cycle specificity, 43 products, 339 Mercapturic acids, butadiene, epoxybutene, Hemoglobin adducts, butadiene, epoxybutene, hemoglobin adducts, rats, 291 mercapturic acids, rats, 291 Metabolism, dibenzanthracenes, bis-dihydro- Hepatocytes, indole-3-carbinol (acid condensa- diols, 261 tion products of), P-450, DT-diaphorase, Metallothionein, heavy metal, metal respon- 303 sive element, DNA-binding protein, mobili- Hepatocytes, quinones, redox cycling, oxi- ty shift assay, 145 dative stress, cytotoxicity, 1 Metal responsive element, heavy metal, HPLC’ with electrochemical detection, metallothionein, DNA-binding protein, N7-(2-hydroxyethyl)guanine, DNA adduct, mobility shift assay, 145 ethylene oxide, 281 Mice, glutathione, oral GSH supplementation, Hydrazine oxidation, 8-hydroxy-2’-deoxy- tissue GSH, 89 guanine, carcinogenesis, hydroxyl radical, Michael addition, pregnane derivative, a,6- 57 unsaturated carbonyl, mechanism of action, Hydroquinone, benzoquinone, superoxide DNA, RNA and protein biosynthesis, dismutase, autoxidation, kinetics, induction cytotoxic and mutagenic potentials, cell period, 159 cycle specificity, 43 Hydroquinone, heme, 1,2,4-benzenetriol, oxy- Mobility shift assay, heavy metal, metallothio- gen radicals, thiobarbituric acid reactive nein, metal responsive element, DNA- products, 339 binding protein, 145 351 Monocyte carboxylesterase, organophos- epoxides, polycyclic aromatic hydrocar- phorus compounds, triphenyl phosphate, bons, 177 327 Pregnane derivative, a,@-unsaturated car- Mutagenicity, singlet oxygen, photosensitiza- bonyl, Michael addition, mechanism of action, genotoxicity, DNA damage, car- tion, DNA, RNA and protein biosynthesis, cinogenicity, 239 cytotoxic and mutagenic potentials, cell cycle specificity, 43 Nitrofurantoin, English sole, oxidative DNA damage, 8-hydroxy-2’-deoxyguanosine, Quinones, hepatocytes, redox cycling, oxi- 317 dative stress, cytotoxicity, 1 Nitronate decomposition, nitropropane, equilibrium, effect of thiols, 187 Rats, butadiene, epoxybutene, hemoglobin ad- Nitropropane, nitronate decomposition, equi- ducts, mercapturic acids, 291 librium, effect of thiols, 187 Reactive oxygen species, butylated hydroxy- Non-cancer fibroblasts, strychnopentamine, anisole, carcinogenicity, mechanism, DNA dimeric indole alkaloid, B16 melanoma, adducts, 109 cytotoxicity, 203 Redox cycling, quinones, hepatocytes, oxidative stress, cytotoxicity, 1 Oral GSH supplementation, glutathione, mice, tissue GSH, 89 Singlet oxygen, photosensitization, genotoxi- Organophosphorus compounds, monocyte car- city, DNA damage, mutagenicity, carboxylesterase, triphenyl phosphate, 327 cinogenicity, 239 Oxidants, peroxidation, liver and intestinal Strychnopentamine, dimeric indole alkaloid, microsomes, 135 B16 melanoma, non-cancer fibroblasts, Oxidative DNA damage, English sole, nitro- cytotoxicity, 203 furantoin, 8-hydroxy-2’-deoxyguanosine, Superoxide dismutase, hydroquinone, benzo- 317 quinone, autoxidation, kinetics, induction Oxidative stress, cytoskeleton, cultured cells, period, 159 217 Oxidative stress, quinones, hepatocytes, redox T4 polynucelotide kinase, postlabeling, cycling, cytotoxicity, 1 1,N®-ethenoadenine, 3,N*-ethenocytosine, Oxygen radicals, heme, hydroquinone, 1,N?-ethenoguanine, DNA adducts, 99 1,2,4-benzenetriol, thiobarbituric acid reac- Thiobarbituric acid reactive products, heme, tive products, 339 hydroquinone, 1,2,4-benzenetriol, oxygen radicals, 339 P-450, indole-3-carbinol (acid condensation Tissue GSH, glutathione, mice, oral GSH sup- products of), hepatocytes, DT-diaphorase, plementation, 89 303 Triphenyl phosphate, monocyte carboxyl- Peroxidation, oxidants, liver and intestinal esterase, organophosphorus compounds, microsomes, 135 327 Photosensitization, singlet oxygen, genotoxicity, DNA damage, mutagenicity, car- a,8-Unsaturated carbonyl, pregnane deriva- cinogenicity, 239 tive, Michael addition, mechanism of ac- Polycyclic aromatic hydrocarbons, *P- tion, DNA, RNA and protein biosynthesis, postlabeling, DNA adducts, V79 cell, diol- cytotoxic and mutagenic potentials, cell epoxides, 177 cycle specificity, 43 Postlabeling, 1,N®-ethenoadenine, 3,N?- ethenocytosine, 1,N?-ethenoguanine, DNA V79 cell, °*P-postlabeling, DNA adducts, diol- adducts, T4 polynucelotide kinase, 99 epoxides, polycyclic aromatic hydrocar- 32P-Postlabeling, DNA adducts, V79 cell, diol- bons, 177 Chem.-Biol. Interactions, 80 (1991) 353 Elsevier Scientific Publishers Ireland Ltd. CHEMICO-BIOLOGICAL INTERACTIONS AUTHOR INDEX VOLUME 80 (1991) Angenot, L. Linhart, I. Aw, T.Y. Maki-Paakkanen, J. Baan, R.A. Malorni, W. Balasubramanian, K.A. Marsman, J.W. Bassleer, R. Mirabelli, F. Bellomo, G. Bergmark, E. Nalini, S. Blaauboer, B.J. Newcombe, D.S. Nishimoto, M. Chalvet, O. Noordhoek, J. Crane, A.E. O’Brien, P.J. Dalal, N.S. Oesch, F. de Kruif, C.A. Osterman-Golkar, S. De Pauw-Gillet, M.-Cl. Otsuka, F. Deininger, C. Duh, C.-Y. Pezzuto, J.M. Duquesne, M. Phillips, D.H. Eder, E. Quetin-Leclercgq, Epe, B. Eyer, P. Rao, G.S. Roubal, W.T. Falke, H.E. Saboori, A.M. Gannett, P.M. Schilderman, P.A.E.L. Gescher, A. Schrode, R. Glatt, H. Seidel, A. Goodwin, B. Shi, X. Grover, P.L. Stein, J.E. Steinbrecher, T. Hahn, H. Strapelias, H. Hakansson, K. Szyfter, K. Hemminki, K. Hewer, A. Toth, B. van Delft, J.H.M. Iosi, F. van Weert, E.J.M. van Winden, M.J.M. Jones, D.P. Varanasi, U. Venekamp, J.C. Kautiainen, A. Verhagen, H. Kinghorn, A.D. Kleinjans, J.C.S. Watson, W.P. Koizumi, S. Wierzbicka, G. Wortelboer, H.M. Lang, D.M. Lecogq, S. Yamada, H. ne