Opinions expressed in the present publication do not necessarily reflect the views of the United Nations Industrial Development Organization (UNIDO) or the International Centre for Science and High Technology (ICS). Mention of the names of firms and commercial products does not imply endorsement by UNIDO or ICS. No use of this publication may be made for resale or for any other commercial purpose whatsoever without prior permission in writing from ICS. This is not a formal document and has been produced without formal editing. ICS-UNIDO is supported by the Italian Ministry of Foreign Affairs © United Nations Industrial Development Organization and the International Centre for Science and High Technology, 2003 Earth, Environmental and Marine Sciences and Technologies ICS-UNIDO, AREA Science Park Padriciano 99, 34012 Trieste, Italy Tel.: +39-040-9228108 Fax: +39-040-9228136 E-mail: [email protected] Preface Medicinal and aromatic plants have played an important role in the socio-cultural, spiritual and health-care needs of rural and tribal people of the emerging and developing countries. In many developing countries, a large section of the population still relies on traditional systems of medicine to meet their health-care needs. Also, more and more people in the developed countries have turned to alternative therapies and herbal medi- cines resulting in many fold increase in the demand of medicinal plants and their products in these parts of the world. On one hand, the global resurgence of interest in medicinal plants provides opportu- nities for the emerging and developing countries to derive economical benefit, and on the other hand, it threatens the existence of natural resources of medicinal plants under the pressure of unsustainable collections and allurements of short-term monetary gains. The demand for medicinal and aromatic plants in the international market has shot-up sud- denly not giving enough time to developing countries to rise to the occasion. Over-har- vesting of high-value or high-demand medicinal plants has already threatened the exist- ence of many valuable plant species. The situation is precariously balanced and requires all countries to make proper assessment of natural resources and sustainable quantities that can be taken out without jeopardizing the interest of our future generations. The utilization of medicinal plants to develop value-added products is under-ex- plored and under-developed in most developing countries except few states like India and China. The lack of appropriate technologies for processing, value addition, standardiza- tion, and inadequate information of domestic resources and international marketing op- portunities are some of the bottlenecks in developing medicinal plant-based industry in the developing countries. The International Centre for Science and High Technology (ICS-UNIDO) in its en- deavour to promote sustainable utilization of medicinal plants in emerging and develop- ing countries, has conducted a series of training courses and workshops to build technical know-how in developing countries, to emphasize the sustainable use of medicinal plant resources and to promote value addition of medicinal plants before they are exported to the international market. From time to time, ICS conducts workshops to update informa- tion on sensitive aspects of medicinal plant industry. In the year 2001, it organized a workshop to discuss the status of medicinal and aromatic plants in different parts of the world and many of the compiled papers in this document were presented at that work- shop. I This publication has consolidated the information generated at different workshops conducted by ICS and gives a detailed account of medicinal and aromatic plant resources, their utilization pattern, R&D activities, marketing and trade situation in different coun- tries of Asia, Africa and Latin America. The document also carries information on qual- ity control and standardization of herbal medicinal products; bio-pesticides and their role in environment; the role of biotechnology in medicinal plants; and trade in herbal medici- nal products. Although the information in this publication is not complete, it gives an overview of the prevailing situation in different parts of the world to stimulate those associated with any aspect of medicinal and aromatic plants. It will serve as information source for policy-makers, scientists, farming community and entrepreneurs to develop strategies for the development of the medicinal plant sector, and to formulate plans for the conservation and sustainable use of medicinal plant biodiversity. Gennaro Longo Area Director Earth, Environmental and Marine Sciences and Technologies II Acknowledgements The Area of Earth, Environmental and Marine Sciences and Technologies of ICS- UNIDO is grateful to the scientific experts who gave wholehearted support to this ICS initiative. Special thanks go to Mr. Francesco Pizzio, Managing Director of ICS-UNIDO, for his constant encouragement throughout the medicinal and aromatic plants activities, to the scientific and secretarial staff of the Area for guidance, compilation, preparation and editorial work, and to the publications staff for their contribution to editorial work. III Contents Page Part 1: Utilization Status of Medicinal and Aromatic Plants 1 1. The Status of Medicinal and Aromatic Plants in Cambodia, Laos, The Philippines, Thailand and Vietnam, Krisana Kraisintu 3 2. The Status of Medicinal and Aromatic Plants in India and Nepal, Karan Vasisht and Maninder Karan 55 3. The Status of Medicinal and Aromatic Plants in Pakistan, Farzana Shaheen, Atta-ur-Rahman , Karan Vasisht and M. Iqbal Choudhary 77 4. The Status of Medicinal and Aromatic Plants in Indonesia, Bambang Mursito, Karan Vasisht and Vishavjit Kumar 89 5. The Status of Herbal Products: the Case of East Africa, Ermias Dagne 103 6. The Status of Medicinal and Aromatic Plants in Central and Southern Africa, Marianne J. Ngoulla 111 7. The Status of Medicinal and Aromatic Plants in Libya, Abdurazag Auzi 119 8. The Experience of the Iberoamerican Programme of Science and Technology for Development in Latin America, Mahabir P. Gupta and Armando Cáceres 125 Part 2: Quality Control and Standardization 141 9. Quality Assurance of Medicinal and Aromatic Plants, Sukhdev Swami Handa and Karan Vasisht 143 10. European Harmonization Efforts for the Quality of Medicinal and Aromatic Plants, Arnold Vlietinck 165 Part 3: Bio-pesticides 173 11. Scope and Potential of Bio-pesticides in the Emerging Environmental Concern, Chika Ukwe 175 Part 4: Biotechnological Applications to Medicinal and Aromatic Plants 199 12. The Role of Biotechnology in Improvement of Medicinal and Aromatic Plants, Maria Luisa Villarreal and Rodolfo Quintero 201 Part 5: Trade 215 13. Trade in Herbal Medicinal Products, Vishavjit Kumar 217 Contributors 235 V Part 1 Utilization Status of Medicinal and Aromatic Plants Chapter 1 The Status of Medicinal and Aromatic Plants in Cambodia, Laos, The Philippines, Thailand and Vietnam by Krisana Kraisintu Introduction Medicinal plants have played a significant role in various ancient traditional systems of medication such as the Chinese, Ayurvedic, Unani, and their secondaries in many Asian countries. Medicinal plants still play an important role in emerging and developing countries of Asia, both in preventive and curative treatments, despite advances in modern western medicine. They also generate income to the people of many Asian countries who earn their livelihood from selling collected materials from the forest, or by cultivating on their farms. The development of modern medicine in the 1900s, along with the introduction of modern drugs produced by pharmaceutical companies, have dealt a strong blow to tradi- tional medicine which was accused of being inefficient, labour-intensive in preparation and, most important, unavailable due to scarcity of raw material. This is exacerbated by the lack of traditional doctors unable to earn a living without basic material (medicinal plants) and demand (customers). The high cost of modern drugs (most of which are imported from the West), their unavailability in remote areas, and, in particular, the serious side effects of certain drugs, have all led the pendulum of medical treatment to swing back to the side of traditional medicine in recent years. The importance and value of traditional and indigenous herbal medicine were the subject of a campaign of the World Health Organization (WHO). This effort, in the 1970s, led to an appeal to all member countries to do their utmost to preserve their national heritage in the form of ethno-medicine and ethno-pharmacology and to bring back the use of known and tested medicinal plants and derivatives into primary health care in rural areas and as alternatives when modern medicine was not available. Moreover, since a large portion of drugs produced by pharmaceutical industry are derived from medicinal plants, the demand for their raw materials is steadily rising. Such demand is met by obtaining material from naturally-occurring plants through indis- criminate collection, or sometimes from cultivated sources. 3 Asia is unique among geographical regions of the world and possesses the highest biological diversity worldwide, deriving from the ecological conditions particularly in the tropical rain forests. There is thus abundant raw material for production of modern drugs. The high diversity of the region is well reflected in a number of species including medicinal plants that are present in the region. Asia is not only rich in biological diversity, but also in cultural diversity. Since the dawn of human history, biodiversity and humanity have become inextricably linked, for example areas of high biological diversity are culturally the most rich, with a large number of distinct communities inhabiting adjacent areas, each with its own language, culture, and system of traditional medicine. The latter category depends on the availability of medicinal plants easily found within the community. A wealth of traditional knowledge about medicinal plants for curing illnesses has been accumulated over a long period and has been handed down from generation to generation. There existed ancient civilization in East and South Asia parallel with cultural di- versity which took place in isolated areas in the jungles of tropical Asia. Unlike the ruins of many empires of other regions, the Chinese and the Indian cultures were quite success- ful, prosperous, and above all, healthy. A simple argument for their being healthy is the number of people presently living in the two most populous countries of the world. Indo- nesia, which is the fourth most populous country, can also claim to have “healthy” people as well as ancient civilization. The peoples in the past had made extensive use of medici- nal plants to cure their ailments based on local knowledge of drugs. From China and India, systems of traditional medicine spread to all other Asian countries. They were later modified and adopted to become systems of their own. Asia has been well known in the modern world as the storehouse of raw material for western pharmaceutical manufacturers. Until the last decade, the majority of these raw materials were easily available from the wild. Along with cheap raw materials, accumu- lated traditional knowledge of native peoples on their use was also exported freely for further development and exploitation by western pharmaceutical companies. Owing to their long history of use by Asian people, an enormous number of medicinal plant species are known to them. The Status of Medicinal and Aromatic Plants in Cambodia Covering an area of 181,035 square km, Cambodia is bordered by Thailand to the west, Laos to the north and Vietnam to the east. Once a French colony, it was the least known Indo-Chinese country. It has a wide basin where farming communities live a sim- ple life, in an original civilization and philosophy of mildness, surrounded by highlands. About 90% of the Cambodian population is Khmer and rest are Chinese, Vietnamese, Chams, Burmese, Thai and small minorities of hill tribes. 4
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