Cephalalgia International Journal ofH eadache VOLUME 16 Cephalalgia Founding Editor, Ottar Sjaastad; Editor-in-Chief, K. M. A. Welch, USA; Assistant Editors, Howard Feit, Nabih Ramadan and Gretchen Tietjen, USA; European Editors, Lars Edvinsson, Sweden and Marcia Wilkinson, UK; Book Review Editor, Anne MacGregor, UK; Historical Section Editor, Hansruedi Isler, Switzerland. EDITORIAL BOARD Frank Andrasik, USA Fabio Facchinetti, Italy Martin Lauritzen, Denmark Birthe K. Rasmussen, Denmark Michael Anthony, Australia Marcello Fanciullacci, Italy Tony J. F. Lee, USA F. Clifford Rose, England Otto Appenzeller, USA M. D. Ferrari, Netherlands Richard B. Lipton, USA David Russell, Norway Bo Bille, Sweden Lars Friberg, USA Ninan Mathew, USA Fumihiko Sakai, Japan J. N. Blau, England Marek J. Gawel, Canada James McCulloch, Scotland Merton Sandler, England Nikolai Bogduk, Australia Vivette Glover, UK Kathleen Ries Merikangas, USA Pramod R. Saxena, Netherlands Marie-Germaine Bousser, France P. J. Goadsby, Australia/London Harold Merskey, Canada Jean Schoenen, Belgium Naomi Breslau, USA Hartmut Gobel, Germany Michael A. Moskowitz, USA Federigo Sicuteri, Italy G. W. Bruyn, Netherlands Steven R. Graff-Radford, USA G. Nappi, Italy Stephen D. Silberstein, USA Gennaro Bussone, Italy Vincenzo Guidetti, Italy Giovanni Nattero, Italy Ottar Sjaastad, Norway Gabriela Buzzi, Italy Jan Hardebo, Sweden Jes Olesen, Denmark D. Soyka, Germany Desmond Carroll, England A. Murray Harper, Scotland John Pearce, UK Egilius L. H. Spierings, USA Giovanni D’Andrea, Italy P. Henry, France Stephen J. Peroutka, USA Felia Titus, Spain Jackie de Belleroche, UK Rachel Hering, Israel V. Pfaffenrath, Germany Walter Stewart, USA Milena De Marinis, Italy Judith Hockaday, England Alison J. Pilgrim, UK Kazuro Takahashi, Japan S. I. Dexter, England Hisaka Igarashi, Japan A. Pradalier, France Peer Tfelt-Hansen, Denmark H. C. Diener, Germany Lee Kudrow, USA A. Prusinski, Poland N. Vijayan, USA Peter Drummond, Australia Ashraf Kurdi, Jordan Edgard Raffaelli, Jr., Brazil Maurice Vincent, Brazil John Edmeads, Canada Arieh Kuritzky, Israel Alan M. Rapoport, USA Elisabet Waldenlind, Sweden Karl Ekbom, Sweden James W. Lance, Australia Neil Hugh Raskin, USA Dewey Ziegler, USA Bjorn Ellertsen, Norway Cephalalgia is included in the ADONIS service. Accordingly, copies of individual articles are available on compact discs (CD-ROM) and can be printed out on demand. An explanatory leaflet is available from the publisher. Information about journals and books from Scandinavian University Press is available on our homepage on the world wide web, URL-address http://www.scup.no PROGRAMME Cephalalgia is published eight times per year and contains original papers on all aspects of headache. The journal provides an international forum for original research papers, review articles, and short communications. Hypotheses may also be published. Supplements are supplied free of charge to the subscribers and copies can be purchased on application to the publisher. Contributions appearing in this journal are abstracted and indexed in Biological Abstracts, Biotechnology Citation Index, Chemical Abstracts (1981-1983), Current Advances in Ecological and Environmental Sciences, Current Contents/Clinical Medicine, Current Contents/Life Sciences (1993-), Excerpta Medica/EMBASE, FaxonFinder, Index Medicus (1981-)/MEDLINE, Index to Dental Literature, INIS Atomindex, Medical Documentation Service, National Epilepsy Library and Resource Center, Neuroepidemiology, Neuroscience Citation Index, Nutrition Research Newsletter, Psychological Abstracts/Psyc INFO (1993-), Nuclear Medicine Literature, Research Alert, Science Citation Index (1993-), SciSearch. MANUSCRIPT ADDRESSES Contributors are requested to send four copies of their manuscripts to: Editor-in-chief of Cephalalgia, K. M. A. 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Email [email protected]. SUBSCRIPTION PRICE One volume (eight issues)—Institutions USD 255.00. IHS members USD 115.00. Nordic countries: Institutions NOK 1530.00. Airmailed to subscribers worldwide. In Japan, all subscriptions should be ordered through the Maruzen Co. Ltd., 3-10 Nihonbashi 2-Chome, Chuo-ku, Tokyo 103, Japan. This journal can be ordered in microform from University Microfilms International, 300 N. Zeeb Rd., Dept. P.R., Ann Arbor, MI 48106, USA. Cephalalgia (ISSN 0333-1024) is published eight times per year by Scandinavian University Press, P.O. Box 2959 Tayen, 0608 Oslo, Norway. Periodical postage paid at Jamaica, NY 11431, USA. Postmasters: Send address changes to Scandinavian University Press North America. Air freight and mailing in the USA by Publications Expediting Inc. © 1996 International Headache Society. 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Typeset and printed in the UK by H. Charlesworth Ltd., Huddersfield. Cephalalgia 1996;16. Oslo. ISSN 0333-1024 Subject index 3,4-dihydroxyphenylacetic acid In vitro pharmacology of electriptan (UK-116,044) a Cerebrospinal fluid tyrosine and potent partial agonist at the ’SHT-1D-like” receptor in 3,4-dihydroxyphenylacetic acid levels in migraine the dog saphenous vein, 386 patients, 56 Preclinical in vivo pharmacology of electriptan 311C90 (Zolmitriptan) (UK-116,044): a potent and selective partial agonist at 311C90 (Zolmitriptan), a novel centrally and peripheral the ’5HT 1D-like” receptor, 386 acting oral 5-hydroxytryptamine-1D agonist: a The aborption potential of electriptan (UK-116,044) and comparison of its absorption during a migraine attack sumatriptan, 387 and in a migraine-free period, 270 A dose-finding study of eletriptan (UK-116,044) 311C90 and sumatripan produce indistinguishable (5-30 mg) for the acute treatment of migraine, 387 CNS adverse event profiles, 389 Minimal interaction between 311C90, a novel The combination of 311C90, a novel antimigraine antimigraine compound, and oral pizotifen, 395 compound, and oral propranolol in healthy subjects, Gender and region difference in side-effects induced 395 by sumatriptan, 396 Minimal interaction between 311C90, a novel The high efficacy of 311C90 in treating migraine antimigraine compound, and oral pizotifen, 395 headaches is maintained in patients using oral The high efficacy of 311C90 in treating migraine contraceptives, 396 headaches is maintained in patients using oral Chest pain and sumatriptan: a disagreeable sensation contraceptives, 396 or a witness for the prosecution, 397 311C90 has no clinically significant effects on blood 311C90 has no clinically significant effects on blood pressure, 398 pressure, 398 Confirmation of the long-term efficacy of 311C90 in the Confirmation of the long-term efficacy of 311C90 in the acute oral treatment of migraine, 399 acute oral treatment of migraine, 399 Confirmation of the long-term safety and efficacy of Confirmation of the long-term safety and efficacy of oral 311C90 in the acute treatment of migraine: oral 311C90 in the acute treatment of migraine: demographic analysis from a study > 20,000 treated demographic analysis from a study > 20,000 treated attacks, 400 attacks, 400 Oral 311C90 is effective in treatment of menstrual Chest symptoms after sumatripan: a two year clinical migraine, 400 practice review in 735 consecutive migraine patients, 5HT agents 554 Sumatriptan: vasoactive effect on human dural vessels, abdominal migraine demonstrated by subselective angiography, 224 Is bowel permeability a measure of abdominal Autoradiographic distribution of [3H] sumatriptan- migraine in children?, 355 binding sites in post-mortem human brain, 317 Is abdominal migraine often environmentally Serotonin syndrome complicating migraine determined?, 378 pharmacotherapy, 323 acetazolamide Zolmitriptan inhibits c-fos expression in the dorsal Acetazolamide as a confirmatory diagnostic test for horn of the medulla and upper cervical horn evoked migraine headaches, 362 by sagittal sinus stimulation in the cat, 355 adhesion molecules Is response to oral sumatriptan in childhood migraine CAM (cell adhesion molecules)-based nitrergic different from adults, 358 mechanisms in experimental migraine, 356 Dose-finding studies of rizatriptan (MK-462) in the agraphia acute treatment of migraine, 359 Agraphia as the only symptom of a migraine aura, 562 The effects of low doses of BMS-180048 compared with alexithymia placebo in acute migraine, 360 Migraine and alexithymia: a Rorschach study, 383 A comparison of oral eletriptan (UK-116,044) alniditan (20-80 mg) and oral sumatriptan (100 mg) in the acute Alniditan in the acute treatment of migraine attacks: a treatment of migraine, 368 subcutaneous dose-finding study, 497 Confirmation of the long-term safety of 311090 in the arteriovenous malformation acute oral treatment of migraine, 372 Cluster headache syndrome associated with middle Efficacy of sumatriptan 50 mg/os in the migraine cerebral artery arteriovenous malformation, 202 attack. Open study on 50 patients, 383 autonomic nervous system Post-marketing clinical use- and misuse- of Autonomic nervous system function in migraineurs sumatriptan in migraine patients: state of the art, 384 during headache-free period: a blood pressure and Can sumatriptan be anxiogenic migraineurs, 384 heart rate variability study, 388 The use of sumatriptan in patients with concomitant Peripheral autonomic potentials in primary headache, epilepsy and migraine, 385 390 The safety, tolerability and pharmacokinetics of Autonomic nervous system and neuroendocrine intravenous electriptan (UK-116,044), a new potent changes in patients with idiopathic trigeminal and selective ’5HT 1D-line” receptor agonist, 385 neuralgia, 476 iv Subject index CEPHALALGIA 16 (1996) blood vessels The International Headache Society classification of Reactions of the middle meningeal artery of the cat to chronic daily and near-daily headaches: a critique of neural and humoral stimulation, 27 the criticism, 407 Sumatriptan: vasoactive effect on human dural vessels, chronic tension-type headache demonstrated by subselective angiography, 224 Exteroceptive suppression of temporal muscle activity Calcitonin gene-related peptide is released from is normal in chronic tension-type headache and not capsaicin-sensitive nerve fibres and induces related to actual headache state, 251 vasodilation of human cerebral arteries concimitant chronic paroxysmal hemicrania with activation of adenylyl cyclase, 310 Neuropeptide changes in a case of chronic paroxysmal Intracerebral arteries and gadolinium enhancement in hemicrannia-evidence for trigemino-parasympathetic migraine without aura, 363 activation, 448 Stimulation of cranial vessels excites neurones in the classification—controversy medial thalamus of the cat, 365 Migraine and tension-type headache are separate Histamine induces relaxation of the human cerebral disorders, 217 artery by activation of endothelial H1-receptors Migraine and tension-type headache are not separate coupled to nitric oxide synthase, 374 disorders, 220 Innervation of the human middle meningeal artery: Are the International Headache Society criteria for immunohistochemistry, ultrastructure and headache useful?, 289 vasomotility, 374 The International Headache Society classification and A novel non-peptide ETA/B receptor antagonist, SB diagnostic criteria are valid and extremely useful, 293 209670, inhibits trigeminal nerve induced effects in the The International Headache Society classification: to carotid vascular bed, 379 use or not to use?, 295 Relationships between cortical spreading depression classification and the parasympathetic cerebrovascular innervation, IHS criteria and gender: a study on migraine and 394 tension-type headache in children and adolesents, 107 Evaluation of non-invasive techniques to assess A nosographic analysis of the migraine aura in a vasoconstriction in healthy volunteers using general population, 380 methoxamine as a probe drug, 507 Migrainous disorder and its relation to migraine BMS-180048 without aura and migraine with aura, 431 The effects of low doses of BMS-180048 compared with The International Headache Society classification of placebo in acute migraine, 360 chronic daily and near-daily headaches: a critique of c-fiber the criticism, 407 Sympathectomy induces C-fiber sprouting and mast cluster headache cell activation in rat dura mater, 370 Pain pressure threshold in cluster headache patients, calcitonin gene-related peptide 62 Calcitonin gene-related peptide is released from IV histamine therapy in intractable cluster headaches, capsaicin-sensitive nerve fibres and induces 357 vasodilation of human cerebral arteries concimitant Study of indole metabolism in cluster headche with activation of adenylyl cyclase, 310 sufferers, 358 H a-CGRP in the middle meningeal and temporal The m-chlorophenylpiperazine test in cluster headache: arteries of man: binding by autoradiography and a study on central serotoninergic activity, 358 vasomotor responses in vitro, 373 Regional cerebral blood flow in patients with cluster cannabis headache during cluster period. A single photon An epidemiological study on the activity of cannabis emission tomography (SPET) study using Tc 99M in idiopathic headache, 377 HMPAO, 365 cerebral blood flow ’“Continuous” cluster like headache with response to Regional cerebral blood flow in patients with cluster sumatriptan and steroids, 392 headache during cluster period. A single photon cluster headache—clinical emission tomography (SPET) study using Tc 99M Cluster headache syndrome associated with middle HMPAO, 365 cerebral artery arteriovenous malformation, 202 cerebrospinal fluid pressure Spectral analysis of heart rate fluctuations in cluster Primary low cerebrospinal fluid pressure syndrome headache, 357 with galactorrhea: findings at MR imaging, 124 Natural history of cluster headache, 390 chest pain Sluder’s syndrome and cluster headache, 391 Chest pain and sumatriptan: a disagreeable sensation Premonitory symptoms and precipitating (triggering) or a witness for the prosecution, 397 factors in cluster headache (CH), 391 chronic daily headache cluster headache—genetics Demographic and clinical characteristics of patients Familial cluster headache, 391 with episodic migraine versus chronic daily headache, cluster headache—treatment 44 Melatonin vs. placebo in the prophyalxis of cluster Psychiatric consultation of patients with chronic daily headache: a double-blind pilot study with parallel headache in Turkey, 393 groups, 494 CEPHALALGIA 16 (1996) Subject index Vv controversy Pain control in migraine attacks: results from a double- The primary headache disorders—apple sauce or fruit blind, randomized, within-patient, placebo-controlled cocktail?, 223 trial comparing diclofenac-K and ergotamine + corticosteroids caffeine, 359 ”Continuous” cluster like headache with response to Effects of ergotamine on myocardial blood flow—a pet sumatriptan and steroids, 392 study, 373 CSF estradiol Cerebrospinal fluid tyrosine and Distinct properties of signal transduction in patients 3,4-dihydroxyphenylacetic acid levels in migraine with migraine, menstrual migraine, postmenopausal patients, 56 headache and effects of estradiol treatment, 356 CT scan event-related potential CT scan in headache patients in an outpatient clinic, Predictability of a migraine attack? An event-related 390 potential study, 363 cyclandelate evoked potentials Cyclandelate in the prophylaxis of migraine: a Pattern reversal visual evoked potentials in children randomized, parallel, double-blind study in with migraine or tension-type headache, 104 comparison with placebo and propranolol, 441 exterocetive suppression depression Exteroceptive suppression of temporal muscle activity Hyperprolactinemia and depression induced by is normal in chronic tension-type headache and not oxetorone, 560 related to actual headache state, 251 dihydroergotamine facial ecchymosis Migraine prophylaxis with slow-release Recurrent paroxysmal headache associated with facial dihydroergotamine, 398 ecchymosis, 341 drug-induced headache factor V Amitryptyline and dexamethasone combined treatment Point mutation (Arg506-Gln) of factor V in migraine in drug-induced headache, 197 with and without aura. A pilot study, 394 Serotonin receptor plasticity in patients with analgesic- familial hemiplegic migraine induced headache, 374 Familial hemiplegic migraine: a clinical comparison of Long-term outcome of patients with headache and families linked and unlinked to chromosome 19, 153 drug abuse after inpatient withdrawal: five-year Stroke as first episode of familial hemiplegic migraine, follow-up, 481 379 electriptan (UK-116,044) Classification problems in familial hemiplegic The safety, tolerability and pharmacokinetics of oral migraine, 384 eletriptan (UK-116,044) a potent and selective 5HT1D- fenfluramine induced headache like receptor agonist, 368 Fenfluramine induced headache: characteristics and A comparison of oral eletriptan (UK-116,044) biochemistry, 364 (20-80 mg) and oral sumatriptan (100 mg) in the acute fibromyalgia treatment of migraine, 368 Fibromyalgia (alias central panalgia): the severest Preclinical in vivo pharmacology of electriptan expression of dysnociception, 366 (UK-116,044): a potent and selective partial agonist at flunarizine the “5HT 1D-like’’ receptor, 386 Post-marketing cohort study comparing the safety and The pharmacokinetics of eletriptan (UK-116,044) in rats efficacy of flunarizine and propranolol in the and dogs, 387 prophylaxis of migraine, 328 The aborption potential of electriptan (UK-116,044) and Long-term follow-up after flunarizine or nimodipine sumatriptan, 387 discontinuation in migraine patients, 337 A dose-finding study of eletriptan (UK-116,044) Freud (5-30 mg) for the acute treatment of migraine, 387 Freud and migraine: the beginning of a electromyographic—biofeedback psychodynamically oriented view of headache a Electromyographic-biofeedback (EMG-BFB) efficacy to hundred years go, 22 treatment of juvenile tension type headache: results at gabapentin 2 years follow-up, 388 Gabapentin in migraine prophylaxis, 367 epidemiology gliadin sensitivity An epidemiological study on the activity of cannabis Screening of gliadin sensitivity in children suffering in idiopathic headache, 377 from migraine, 393 An epidemiologic study of headache among children glyceryl trinitrate and adolescents, 545 Glyceryl trinitrate produces prolonged changes in epilepsy cortical nitric oxide release in the anaesthetized cat, Occipital paroxysms in children with migraine and 379 epilepsy, 364 head trauma The use of sumatriptan in patients with concomitant Migraine associated with head trauma, 375 epilepsy and migraine, 385 headache ergotamine An epidemiological study on the activity of cannabis Side effects of ergotamine, 5 in idiopathic headache, 377 vi Subject index CEPHALALGIA 16 (1996) headache—clinical idiopathic stabbing headache A quality of life instrument for adolescents with Idiopathic stabbing headache (jabs and jolts chronic headache, 183 syndrome), 93 Differential sensitivity to morphine challenge in induced headache migraine sufferers and headache-exempt subjects, 297 Serotonin receptor adaptation in patients with Recurrent paroxysmal headache associated with facial analgesic induced headache, 419 ecchymosis, 341 Platelet serotonin in patients with analgesic induced CT scan in headache patients in an outpatient clinic, headache, 423 390 ketamine headache—historical Relief of migraine attack with N-methyl-D-aspartic Freud and migraine: the beginning of a acid receptor antagonist ketamine: a double-blind psychodynamically oriented view of headache a comparison with placebo-theoretic implications, 372 hundred years go, 22 m-chlorophenylpiperazine Headache as an occupational illness in the treatise ‘De The m-chlorophenylpiperazine test in cluster headache: morbis artificum diatriba” of Bernardino Ramazzini, a study on central serotoninergic activity, 358 87 magnesium A 6th Century Irish headache cure and its use in a Prophylaxis of migraine with oral magnesium; results South Germany monastery, 536 from a prospective, multi-center, placebo-controlled headache—epidemiology and double-blind randomized study, 257 Electrominographical ischemic test symptom Epidemiological study of headache in childhood, 401 evaluation and intra and extracellular magnesium headache—pathogenesis Peripheral autonomic potentials in primary headache, concentration in headache patients, 402 Magnesium in the prophylaxis of migraine—double- 390 blind placebo controlled study, 436 Electrominographical ischemic test symptom magnetic resonance imaging evaluation and intra and extracellular magnesium Brain MRI in children with migraine, 541 concentration in headache patients, 402 mast cell headache—pediatric Sympathectomy induces C-fiber sprouting and mast Pattern reversal visual evoked potentials in children cell activation in rat dura mater, 370 with migraine or tension-type headache, 104 melatonin IHS criteria and gender: a study on migraine and Melatonin vs. placebo in the prophyalxis of cluster tension-type headache in children and adolesents, headache: a double-blind pilot study with parallel 107 groups, 494 Recurrent ophthalmoplegia in childhood: diagnostic menstrual migraine and etiologic considerations, 276 “Menstrual” migraine: towards a definition, 11 Is bowel permeability a measure of abdominal Distinct properties of signal transduction in patients migraine in children?, 355 with migraine, menstrual migraine, postmenopausal Occipital paroxysms in children with migraine and headache and effects of estradiol treatment, 356 epilepsy, 364 Oral 311C90 is effective in treatment of menstrual The results of two studies on the behaviorial treatment migraine, 400 of young headache patients, 367 Platelet serotonin pathway in menstrual migraine, 427 Brain MRI in children with migraine, 541 Variations in the platelet arginine/nitric oxide An epidemiologic study of headache among children pathway during the ovarian cycle in females affected and adolescents, 545 by menstrual migraine, 468 headache—therapy methoxamine Ketoprofen, paracetamol and placebo in the treatment Evaluation of non-invasive techniques to assess of episodic tension-type headache, 117 vasoconstriction in healthy volunteers using hemicrania methoxamine as a probe drug, 507 Hemicrania with trigeminal neuralgia, 380 middle meningeal artery histamine Reactions of the middle meningeal artery of the cat to IV histamine therapy in intractable cluster headaches, neural and humoral stimulation, 27 357 migraine Histamine induces relaxation of the human cerebral The primary headache disorders—apple sauce or fruit artery by activation of endothelial H1-receptors cocktail?, 223 coupled to nitric oxide synthase, 374 migraine—clinical Histamine inhalation is a specific but insensitive Menstrual” migraine: towards a definition, 11 laboratory test for migraine, 550 Demographic and clinical characteristics of patients hyperprolactinemia with episodic migraine versus chronic daily headache, Hyperprolactinemia and depression induced by 44 oxetorone, 560 Pattern reversal visual evoked potentials in children hypertension headache with migraine or tension-type headache, 104 Simultaneous therapeutic intervention in patients with IHS criteria and gender: a study on migraine and headache and arterial hypertension, 382 tension-type headache in children and adolesents, 107 CEPHALALGIA 16 (1996) Subject index vii Should we investigate migraine of late onset?, 201 Red wine-induced release of “CJ5-hydroxytryptamine Migraine and tension-type headache are separate from platelets of migraine patients and controls, 41 disorders, 217 Cerebrospinal fluid tyrosine and Migraine and tension-type headache are not separate 3,4-dihydroxyphenylacetic acid levels in migraine disorders, 220 patients, 56 Distinct properties of signal transduction in patients Inhalational anesthetics inhibit spreading depression: with migraine, menstrual migraine, postmenopausal relevance to migraine, 87 headache and effects of estradiol treatment, 356 Regional cerebral blood flow (rCBF) in migraine Migraine without aura and migaine with aura are during the interictal period: different rCBF patterns in distinct clinical entities; a study of 484 male and patients with and without aura, 161 female migraineurs from the general population, 361 Zolmitriptan inhibits c-fos expression in the dorsal Acetazolamide as a confirmatory diagnostic test for horn of the medulla and upper cervical horn evoked migraine headaches, 362 by sagittal sinus stimulation in the cat, 355 Predictability of a migraine attack? An event-related Intracerebral arteries and gadolinium enhancement in potential study, 363 migraine without aura, 363 Risk factors for a poor outcome of migraine without Sympathectomy induces C-fiber sprouting and mast aura. A case-control study, 369 cell activation in rat dura mater, 370 Migraine associated with head trauma, 375 Parasympathetic stimulation induces plasma protein Perception of health and quality of life of people with extravasation in rat dura mater, 370 frequent migraine attacks, 376 Red wine and vodka differ in their ability to reduce stress, 378 The relevance of psychological factors in migraine, 377 Glyceryl trinitrate produces prolonged changes in Clinical pattern and psychic sequelae of migraine, 378 cortical nitric oxide release in the anaesthetized cat, Hemicrania with trigeminal neuralgia, 380 379 The hyperventilation migraine—a new clinical entity?, Persistent pain and non-painful disagreeable sensation 381 after overdistension test stress the entity of “pain Migraine and alexithymia: a Rorschach study, 383 memory” linked to the long-term potentiation in Histamine inhalation is a specific but insensitive migraine sufferers, 380 laboratory test for migraine, 550 Electroencephalogram and transcranial Doppler in migraine—epidemiology migraine with aura and in confusional migraine in MIG ACCESS: a population-based, nationwide, children, 388 comparative survey of access to care in migraine in Autonomic nervous system function in migraineurs France, 50 during headache-free period: a blood pressure and Work-related disability: results from the American heart rate variability study, 388 migraine study, 231 Discrimination between migraine patients and normals Migraine without aura and migraine with aura are based on the steady-state visual evoked potentials and distinct clinical entities: study of 484 male and female (SSVEPs): discriminant analysis and artificial neuronal migraineurs from the general population, 239 network methods, 389 Incidence of severe migraine in the gazel cohort, 361 Migraine and oxidative stress involvement on platelet A nosographic analysis of the migraine aura in a responsiveness, 395 general population, 380 Platelet serotonin pathway in menstrual migraine, 427 migraine—genetics Visual system dysfunction in migraine: a review of Familial hemiplegic migraine: a clinical comparison of clinical and psychophysical findings, 525 families linked and unlinked to chromosome 19, 153 migraine—pediatric The family history of migraine. Direct versus indirect Is response to oral sumatriptan in childhood migraine information, 156 different from adults, 358 Migraine without aura and migraine with aura are Headaches not fulfilling the criteria of migraine and inherited disorders, 305 tension-type headache a follow-up study in children Migrainous disorder and its relation to migraine and adolescents, 362 without aura and migraine with aura. A genetic Migraine with aura in childhood and adolescence— epidemiological study, 362 clinical features of the aura, 376 The family history of migraine. Direct versus indirect Is abdominal migraine often environmentally information, 392 determined?, 378 Analysis of 31 families with an apparently autosomal Electroencephalogram and transcranial Doppler in dominant transmission of migraine with aura in the migraine with aura and in confusional migraine in nuclear family, 393 children, 388 Point mutation (Arg506-Gln) of factor V in migraine Epidemiological study of headache in childhood, 401 with and without aura. A pilot study, 394 migraine—neurophysiology Migraine association and linkage analyses of an MSPI Photic driving in migraine: correlations with clinical polymorphism in the human 5HT2a receptor gene, 463 features, 246 migraine—pathogenesis migraine—therapy Painful vein overdistension in migraine patients: no Pilot study of MK-462 in migraine, 113 relationship with serotoninergic parameters, 37 Prophylaxis of migraine with oral magnesium; results viii Subject index CEPHALALGIA 16 (1996) from a prospective, multi-center, placebo-controlled The aborption potential of electriptan (UK-116,044) and and double-blind randomized study, 257 sumatriptan, 387 Risk factors for headache recurrence after sumatriptan: A dose-finding study of eletriptan (UK-116,044) a study in 366 migraine patients, 264 (5-30 mg) for the acute treatment of migraine, 387 311C90 (Zolmitriptan), a novel centrally and peripheral 311C90 and sumatripan produce indistinguishable acting oral 5-hydroxytryptamine-1D agonist: a CNS adverse event profiles, 389 comparison of its absorption during a migraine attack Screening of gliadin sensitivity in children suffering and in a migraine-free period, 270 from migraine, 393 Serotonin syndrome complicating migraine Minimal interaction between 311C90, a novel pharmacotherapy, 323 antimigraine compound, and oral pizotifen, 395 Long-term follow-up after flunarizine or nimodipine The combination of 311C90, a novel antimigraine discontinuation in migraine patients, 337 compound, and oral propranolol in healthy subjects, Pain control in migraine attacks: results from a double- 395 blind, randomized, within-patient, placebo-controlled The high efficacy of 311C90 in treating migraine trial comparing diclofenac-K and ergotamine + headaches is maintained in patients using oral caffeine, 359 contraceptives, 396 Dose-finding studies of rizatriptan (MK-462) in the Resolution without discomfort of analgesic drug abuse acute treatment of migraine, 359 by suign 24 hours infusion of NMDA receptor The effects of low doses of BMS-180048 compared with antagonist in migraine, 397 placebo in acute migraine, 360 Migraine prophylaxis with slow-release Gabapentin in migraine prophylaxis, 367 dihydroergotamine, 398 A comparison of oral eletriptan (UK-116,044) 311C90 has no clinically significant effects on blood (20-80 mg) and oral sumatriptan (100 mg) in the acute pressure, 398 treatment of migraine, 368 Clinical effectiveness of verapamil in the management The safety, tolerability and pharmacokinetics of oral of migraine pain: a retrospective analysis, 398 eletriptan (UK-116,044) a potent and selective 5HT1D- Oral 311C90 is effective in treatment of menstrual like receptor agonist, 368 migraine, 400 Relief of migraine attack with N-methyl-D-aspartic Confirmation of the long-term safety and efficacy of acid receptor antagonist ketamine: a double-blind oral 311C90 in the acute treatment of migraine: comparison with placebo-theoretic implications, 372 demographic analysis from a study > 20,000 treated Effects of ergotamine on myocardial blood flow—a pet attacks, 400 study, 373 Headache induced by a nitric oxide donor Sodium valproate in the prevention of migraine: case (nitroglycerin) responds to sumatriptan. A human studies on the effect of withdrawal of long term model for development of migraine drugs, 412 therapy, 377 Alniditan in the acute treatment of migraine attacks: a migraine—treatment subcutaneous dose-finding study, 497 Side effects of ergotamine, 5 Post-marketing cohort study comparing the safety and Chest symptoms after sumatripan: a two year clinical efficacy of flunarizine and propranolol in the practice review in 735 consecutive migraine patients, prophylaxis of migraine, 328 554 Confirmation of the long-term safety of 311090 in the Magnesium in the prophylaxis of migraine—double- acute oral treatment of migraine, 372 blind placebo controlled study, 436 Effects of orally administrered naltrexone in healthy Cyclandelate in the prophylaxis of migraine: a randomized, parallel, double-blind study in volunteers and migraine sufferers, 381 Nabumetone in migraine prophylaxis, 382 comparison with placebo and propranolol, 441 Efficacy of sumatriptan 50 mg/os in the migraine migraine with aura attack. Open study on 50 patients, 383 Migraine with aura in childhood and adolescence— Can sumatriptan be anxiogenic migraineurs, 384 clinical features of the aura, 376 Post-marketing clinical use- and misuse- of migraine without aura sumatriptan in migraine patients: state of the art, 384 Migraine without aura and migraine with aura are The safety, tolerability and pharmacokinetics of distinct clinical entities: study of 484 male and female intravenous electriptan (UK-116,044), a new potent migraineurs from the general population, 239 and selective ’5HT 1D-line” receptor agonist, 385 migraine without aura—treatment The use of sumatriptan in patients with concomitant Preventive drug use in migraine without aura, 383 epilepsy and migraine, 385 migrainous otalgia In vitro pharmacology of electriptan (UK-116,044) a Migrainous otalgia—a new syndrome, 401 potent partial agonist at the ’’SHT-1D-like” receptor in morphine the dog saphenous vein, 386 Differential sensitivity to morphine challenge in Preclinical in vivo pharmacology of electriptan migraine sufferers and headache-exempt subjects, (UK-116,044): a potent and selective partial agonist at 297 the ’5HT 1D-like” receptor, 386 MR imaging The pharmacokinetics of eletriptan (UK-116,044) in rats Primary low cerebrospinal fluid pressure syndrome and dogs, 387 with galactorrhea: findings at MR imaging, 124