Cell & Tissue Biology Research

341 Pages·2017·6.49 MB·English

ISSN: 1309 2375

Official Publication of the Turkish Society of Histology and Embryology

Cell & Tissue Biology Research

Turkish Histology and Embryology Association

www.ctbiol.com

Volume 6 / 2018 Supplement
Special Issue
includes abstracts of the 14th
National Histology and
Embryology Congress
10-13 May 2018
Hotel Su
Antalya / Türkiye
Official Publication of the Turkish Histology and Embryology Association
About the Journal
Cell and Tissue Biology Research is an official journal of the Turkish Histology and Embryology Association. It is
an online journal publishing research articles after full peer review. All articles are published, without barriers to
access, immediately upon acceptance. One volume is published every year. Each volume consists of 4 numbers
published quarterly online.
Aims and Scope
Cell and Tissue Biology Research is a peer-reviewed journal that publishes original research on all aspects of
anatomy, histology, cell biology and fine structure of tissues and organs on light and electron microscopical
level, neuroanatomy, and morphological techniques, as well as developmental biology, focusing on
morphogenesis—the study of the emergence of form during embryogenesis, mechanisms of development,
differentiation, and growth in animals and plants at the molecular, cellular, and genetic levels. Published
manuscript styles include original research articles, review articles, technical notes, case reports, short
communications, and letters to the editor. Novel features include: full peer review, high quality of reproduction,
rapid publication, no page charges, wide readership, and fast track submission.
Indexing and archiving
Cell and Tissue Biology Research aims to be indexed in all major national and international databases in the
neer future.
Copyright
All rights reserved. Apart from any relaxations permitted under national copyright laws, no part of this
publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means
without the prior written permission of the copyright owners. Permission is not required to copy summaries of
papers or of articles on the condition that a full reference to the source is given. Multiple copying of the
contents without permission is always illegal.
Contact Information
Queries about content, submissions, or the review process should be directed to the Turkish Histology and
Embryology Association.
If you have proposals or feedback related to this journal or this field of science, please do not hesitate to
contact the Managing Editor Dr.A. Cevik Tufan, E-mail:
Manuscript Submission
Manuscripts and illustrations should be submitted in English, online to the editorial office. Authors should retain
their own copy, as the Editor cannot accept responsibility for damage or loss of manuscripts.
The text document must be saved as Word or RTF format. Tables must be included in the text document.
Figures must be saved in the formats and at the resolution indicated below (illustrations section).
The manuscript should be typed double-spaced throughout on one side of A4 paper with at least a 2.5 cm
margin on all sides. Do not divide words at the end of lines. Pages should be numbered consecutively in Arabic
numerals, beginning with the title page.
Prepare a cover letter and a copyright transfer form signed by all authors.
Organize the manuscript as follows: title page, abstract (including key words at the end), introduction, material
and methods, results, discussion (including the conclusions), acknowledgments, references, figure legends, and
tables.
Keep acronyms and abbreviations to a minimum. When an abbreviation is used, define it at first mention and
follow with the abbreviation in parentheses.
Categories of Submission
Review Articles
Cell and Tissue Biology Research publishes review articles on the basis of invitation by the editor(s). However,
author(s) is free to suggest topics and manuscripts for publication in the journal as a rewiev article as well. The
author(s) is absolutely free to design the paper. There is no limitation in the page count in this category.
References, figures, and legends follow the guidelines described below under ‘Original Articles.’ The Abstract
section is needed.
Original Articles
Title Page. The following information should appear: title of article; authors’ name, and last name; affiliations
with complite addresses. Identify the corresponding author and provide full mailing address, phone and fax
numbers, and e-mail address. Also provide a short running title (no more than 40 spaces).
Abstract. The abstract is limited to 400 words, and should describe the essential aspects of the investigation. In
the first sentence state the background; in the second sentence state your specific purpose or hypothesis; in
the third, fourth and fifth sentences summarize methods, results and conclusion. No references should be cited.
For indexing purposes, a small number of "key words" (no more than 5) must be supplied.
Introduction. Include brief background information on what has been done in the past in this area and the
importance of your investigation. End with a statement of the purpose or hypothesis of the study.
Material and Methods. This section may be divided into subsections if it facilitates reading the paper. The
research design, subjects, material used, and statistical methods should be included. Do not mix results and
discussion into this section. Do not include manufacturer’s names unless the specific product is important to the
procedures performed, in which case the city and state or country of the manufacturer should also be given.
Indicate that informed consent has been obtained from patients who participated in clinical investigations. In
animal experimentation, acknowledge that ethical guidelines were followed. When appropriate, indicate that
approval was obtained from the institution’s review board.
Results. This section may be divided into subsections if it facilitates reading the paper. All results based on
methods must be included. If tables and graphic material will ease the understanding of the results, include
them. Cite figures to illustrate the findings of the study.
Discussion. Start with limited background information and then discuss the results of the investigation in light
of what has been published in the past, the limitations of your study, and potential directions for future
research. In appropriate place, cite figures and graphs. Following this information, summarize the major
findings of the study and their clinical usefulness. This paragraph should address the hypothesis or purpose
stated earlier in the paper.
Acknowledgments. Acknowledgments should appear on a separate page. Tis section also has to include the
grant information (if any) of the investigators.
References. Section must be double spaced and begin on a separate page. References to the literature should
be cited in the text by the name of the author(s) followed by the year of publication. In cases in which there are
more than two authors, only the first is named, followed by "et al.". Examples: Smith (1980) reported that...;
(Smith, 1980, 1982); (Smith and Tanaka, 1980); (Smith et al., 1980). Suffixes a, b, etc., should be used
following the year to distinguish two or more papers by the same author(s) published in the same year;
example (Smith, 1981a). When two or more references are included in the same bracket, they must be quoted
in the chronological order; example (Smith, 1980; Bell et al., 1984). All references must be cited in the text,
and all authors should be listed in references. The reference list should be in alphabetical order.
References to articles in periodical publications must include: Names and initials of all authors, year of
publication, complete title of paper, name of journal (abbreviated in accordance with Index Medicus), number
of volume, and first and last page numbers. Example: Morita T., Suzuki Y. and Churg J. (1973). Structure and
development of the glomerular crescent. Am. J. Pathol. 72, 349-368.
References to books must include: Name and initials of authors, year of publication, full title, edition, editor,
publisher, place of publication and page numbers. Example: Powell D. and Skrabanek P. (1981). Substance P.
In: Gut Hormones. 2nd ed. Bloom S.R. and Polak J.M. (eds). Churchill Livingstone. Edimburgh. pp 396-401.
References to URL (Web Page) must include: Name and initials of URL owners, full title of the URL, address,
and accession date in pharantheses. Example: Stern M. Radial nerve entrapment.
http://www.emedicine.com/orthoped/topic549.htm (accessed Dec 2005).
Tables. Each table should be given on a separate page. Each table has a short, descriptive title. Tables are
numbered in the order cited in the text. Abbreviations are defined as footnotes at the bottom of each table.
Tables should not duplicate data given in the text or figures.
Figures and Legends. The complete sets of original figures must be submitted. Subjects’ names must not
appear on the figures. Labels should contrast well with the background. Images should be uniform in size and
magnification. Illustrations should be free of all identifying information relative to the subject and institution.
Line drawings should be professional in quality. Written permission for use of all previously published
illustrations must be included with submission, and the source should be referenced in the legends. Written
permission from any person recognizable in a photo is required. Legends must be double spaced, and figures
are numbered in the order cited in the text. Submit color prints only if color is essential in understanding the
material presented. Label all pertinent findings.
Illustrations should be labelled with the figure number and author's name in soft pencil on the back identifying
the top edge. Photographs should be glossy bromide prints of good contrast and well matched, preferably not
mounted on card. Photographs should not exceed 17.8 x 22.2 cm. The Editor reserves the right to reduce or
enlarge the illustrations. Colour photographs will be allowable only in special circumstances. Line diagrams
should be drawn with black ink on tracing paper or white card or supplied as glossy prints. Illustrations should
be submitted protected by resistant cardboard. Apply figure numbers to the lower left-hand corner of each
photograph; dry transfer lettering (such as letraset) may be used. Digital images are welcome. They must be
submitted on CDROM (CD-r or CD-RW) only. We cannot use other types of disk. Images should be TIFF file
format, preferentially, although other formats could be useful. Black and white figures must be at gray scale.
Color figures should be preferentially in CMYK, but RGB is also allowed. Line art files must have a 500dpi
resolution, while other images must have a 300dpi resolution. Supplying digital images is not a substitute for
the press set of figures.
Technical Notes
While the journal encourages the submission of full-length original articles, it will consider the publication of
technical notes describing the characteristics of new instruments
of methodological improvements. In addition to a title page (formatted as described above), include a summary
(250 word) describing the essence of the report, an introduction (two or three sentences of background
information), a description of the technique, and a discussion highlighting the educational value of the
technique. References should be limited (no more than 10 preferred) to only those that give essential
background material. References, figures, and legends follow the guidelines described above in ‘Original
Articles.’
Short Communications
While the journal encourages the submission of full-length original articles, it will consider the publication of
short communications ensuring rapid publication of new/preliminary results of unusually educational and
medically important. Whole manuscript should be maximum of 3 pages, containing maximum of 1 figure, and 1
table. In addition to a title page (formatted as described above), include a summary (250 word) describing the
essence of the report, an introduction (two or three sentences of background information); materails and
methods, results and a discussion highlighting the educational value of the case. References should be limited
(no more than 10 preferred) to only those that give essential background material. References, figures, and
legends follow the guidelines described above in ‘Original Articles.’
Case Reports
While the journal encourages the submission of full-length original articles, it will consider the publication of
concise case reports. These should be unusually educational and medically important. In addition to a title page
(formatted as described above), include a summary (250 word) describing the essence of the report, an
introduction (two or three sentences of background information); the case report (written in the past tense),
and a discussion highlighting the educational value of the case. References should be limited (no more than 10
preferred) to only those that give essential background material. References, figures, and legends follow the
guidelines described above in ‘Original Articles.’
Letters to the Editor
Letters to the Editor may be used to describe in an extremely brief manner either an observation of interest to
our readers, an opinion relative to the Cell and Tissue Biology Research, or constructive observations or
criticisms of published material. Letters should be no more than two pages and should be submitted with a brief
title. A maximum of four references may be included. Letters are published at the discretion of the journal and
are subject to editing.
Cell and Tissue Biology Research Editorial Board
Co-Editors-in-Chief:
Attila DAĞDEVĠREN
ġahin A. SIRMALI
Managing Editor:
A. Çevik TUFAN
Language Editor:
Selma YÖRÜKAN
Statistical Advisor:
Ergun KARAAĞAOĞLU
Section Editors:
Biomaterial Sciences & Biotechnology :
Petek KORKUSUZ
Cardiovascular and Endothelial Research:
Candan ÖZOĞUL, Sevda F. MÜFTÜOĞLU
Cell structure and function - biophysics:
Selma YILMAZER, Nuhan PURALI
Embryology and teratotoxicology:
Deniz ERDOĞAN, Nur ÇAKAR
Image Processing and Stereology:
E. Oğuzhan OĞUZ
Immune System and Hematology:
Esin AġAN, Esra ATABENLĠ
Metabolism: Digestive, Urinary and Respiratory Systems:
Belgin CAN, Ufuk METE
Microscopy- techniques:
Zeynep KAHVECĠ, Tangül ġAN
Musculoskeletal and Integumentary Systems:
Serap ARBAK
Neuroscience:
Hakkı DALÇIK, Özhan EYĠGÖR
Proteomics- Genomics:
Feride ġAHĠN, N.Lale ġATIROĞLU-TUFAN
Reasearch and Academic Ethics:
ġahin SIRMALI, Pergin ATĠLLA
Reproductive System & Assisted Reproduction:
Ramazan DEMĠR, Firdevs GÜRER
Stem Cell Research- Culture:
Alp CAN, Ayhan BĠLĠR
Scientific Advisory Board (THEA members)
Alpaslan GÖKÇĠMEN
Aysel KÜKNER
Aydın KETANĠ
Aytekin ÖZER
Belma ALABAY
Bizden SABUNCUOĞLU
Cengiz BAYÇU
Emin Türkay KORGUN
Erdoğan GÜRSOY
Erinç ARAL
Feral ÖZTÜRK
Feriha ERCAN
Figen KAYMAZ
Gülten KARABAY
H.Seda VATANSEVER
Hikmet ALTUNAY
Ġlkin ÇAVUSOĞLU
Kazım TUĞYAN
Leyla CANPOLAT
M.Kemal ÖZBĠLGĠN
Melda YARDIMOĞLU YILMAZ
Meral BAKA
Meral ÖNCÜ
Mine YAKIġIK
Mukaddes EġREFOĞLU
Murat YAĞMURCA
Nevin KURTDEDE
Nigar VARDI
Özgül TAP
Sait POLAT
Selçuk DUMAN
Serap Sergül ĠNANÖZ
Sevinç ĠNAN
ġule ÇETĠNEL
Süreyya CEYLAN
Suzan DAĞLIOĞLU
Varol ġAHĠNTÜRK
Yavuz TEKELĠOĞLU
Yusuf NERGĠZ
COPYRIGHT RELEASE FORM
Turkish Histology and Embryology Association (THEA)
Tezel sok 4/4 Yukarıayrancı, 06550 Ankara
Turkey
Journal title: Cell and Tissue Biology Research.
Manuscript title: ............................................................................................................................. ...................
......................................................................................................................................................................
......................................................................................................................................................................
Full names of all authors (in order to appear on manuscript): ......................................................................................
......................................................................................................................................................................
Name, address etc. of corresponding author: ............................................................................................................
...................................................................................................................................... ................................
......................................................................................................................................................................
ID Number: ....................................................... Telephone: ......................................................................
E-mail: ............................................................. Mobile phone: ..................................................................
The author(s) warrant(s) that:
a) the manuscript submitted is his/her/their own original work;
b) all authors participated in the work in a substantive way and are prepared to take public responsibility for the work;
c) all authors have seen and approved the manuscript as submitted;
d) the manuscript has not been published and is not being submitted or considered for publication elsewhere;
e) the text, illustrations, and any other materials included in the manuscript do not infringe upon any existing copyright or other rights of
anyone.
Notwithstanding the above, the Contributor(s) or, if applicable the Contributor(s) Employer, retain(s) all proprietary rights other than copyright,
such as
a) patent rights;
b) to use, free of charge, all parts of this article for the author(s) future works in books, lectures, classroom teaching or oral presentations;
c) the right to reproduce the article for their own purposes provided the copies are not offered for sale.
However, reproduction, posting, transmission or other distribution or use of the article or any material contained therein, in any medium as
permitted hereunder, requires a citation to the Journal and appropriate credit to THEA as publisher, suitable in form and content as follows:
Title of article, author(s), journal title and volume/issue, Copyright© year.
All materials related to manuscripts, accepted or rejected, including photographs, original figures etc., will be kept by THEA for one year
following the editorÕs decision. These materials will then be destroyed.
I/We indemnify THEA and the Editors of the Journals, and hold them harmless from any loss, expense or damage occasioned by a claim or
suit by a third party for copyright infringement, or any suit arising out of any breach of the foregoing warranties as a result of publication of
my/our article. I/We also warrant that the article contains no libelous or unlawful statements and does not contain material or instructions that
might cause harm or injury.
This copyright form must be signed by all authors. Separate copies of the form (completed in full) may be submitted by authors located at
different institutions; however, all signatures must be original.
ID number: ............................................................. ID number: ...........................................................
Full name (block letters) ...................................... Full name (block letters) .........................................
Signature ......................... Date ............. Signature ...................... Date ...........................
ID number: ......................................................... ID number: ...........................................................
Full name (block letters) ...................................... Full name (block letters) .........................................
Signature ......................... Date ............... Signature ...................... Date ...........................
ID number: ......................................................... ID number: ...........................................................
Full name (block letters) ...................................... Full name (block letters) .........................................
Signature ......................... Date ............... Signature ...................... Date ...........................
Turkish authors must supply their ID card number; foreign authors must supply their passport number.
KONGRE PROGRAMI
& ÖZET KİTABI
*Kongremiz TÜBİTAK-BİDEB 2223-B Yurtiçi Bilimsel Etkinlik Düzenleme Desteği almıştır.
14. Ulusal Histoloji ve Embriyoloji Kongresi 10-13 Mayıs 2018, Antalya - Türkiye
ÖNSÖZ
Türk Histoloji ve Embriyoloji Derneği’nin Saygıdeğer Üyeleri,
Göz açıp kapayıncaya kadar hızlı geçen bir dönemin daha ardından sizlerle derneğimizin 14. Ulusal
Kongresinde bir araya gelebilmenin heyecanını ve mutluluğunu yaşıyoruz. Bildiğiniz gibi, 14. Ulusal
Histoloji ve Embriyoloji Kongresi, Türk Histoloji ve Embriyoloji Derneği (THED) tarafından
düzenlenmekte olup, 10-13 Mayıs 2018 tarihlerinde, Hotel Su, Antalya’da gerçekleştirilecektir. Bu
yılkı kongre sloganımızı “Hücre Hayattır” olarak seçtik. Kongremizin, geçmiş toplantılarımızda olduğu
gibi tüm katılımcılarımıza hem bilimsel hem de sosyal anlamda güzel ve unutulmaz anılar yaşatması
en büyük arzumuzdur.
THED, kurulduğu 1990 yılından bugüne, üye sayısını her geçen gün arttırarak güçlenmiş; alanını
temsil eden tek meslek derneği olarak; üyelerinin eğitim, hizmet ve araştırma alanlarındaki
etkinliklerini ulusal ve uluslararası platformlarda desteklemeyi amaç edinmiştir. İki yılda bir
gerçekleştirilen ulusal kongrelerimiz bu etkinliklerin en önemli bölümünü oluşturmaktadır.
Derneğimizin kuruluşunun 28. yıl dönümünü de kutladığımız bu yıl ki kongremizde, 88 sözlü, 118
poster bildirisi olmak üzere toplam 206 bilimsel bildiri sunulacak ve tartışılacaktır. Kongremizde
sunulacak bildirilerin konulara göre dağılımı incelendiğinde ÜYTE, implantasyon, plasenta, üreme
sistemi, embriyoloji ve teratoloji, tümör biyolojisi, Histoloji ve Embriyoloji’de sistemler, kök hücreler
ve tedavide kullanımı, Histoloji ve Embriyoloji’de yeni teknolojik yaklaşımlar, DNA-hücre-doku hasarı
ve onarımı, stereolojik yaklaşımlar ve sinir bilimleri gibi çok geniş bir yelpazeyi kapsadığı
görülmektedir. Kongremizde ayrıca, 4 bireysel konferans, 4 ayrı panelde 10 panel sunumu, 1 bireysel
fotoğraf gösterisi ve 2 farklı firma tarafından gerçekleştirilecek 2 uydu sempozyumu yer alacaktır.
Davetli konuşmaların başlıkları arasında ise CRISPR-Cas devrimi, deneysel modellerde mezenşimal
kök hücre uygulamaları, lab-on-a-chip teknolojisi ve akademik girişimcilik, şirketleşme ve gelir
modelleri gibi güncel ve önemli konular yer almaktadır.
Her ulusal kongremizde olduğu gibi, bu yıl da davetli konuşmalar, sözlü ve poster sunularının Türkçe
özetlerini elektronik olarak Cell and Tissue Biology Research dergimizde yayımlıyoruz. Dergimizde
paylaştığınız bilgi ve deneyimlerinizin histoloji ve embriyoloji alanına çok önemli katkılar
sağlayacağına inanıyoruz.
Bilimsel etkinliklerimizin yanı sıra THED 15. Olağan Genel Kurulunun ve hemen ardından
gerçekleştirilecek olan Kongre Gala Yemeğinin, birlik ve beraberliğimizi pekiştirecek güzel anılara
vesile olmasını yürekten arzulamaktayız. Geçmiş yıllarda olduğu gibi bu yıl da meslekte 30. yılını
dolduran değerli meslektaşlarımıza ve bir önceki kongremizden bugüne geçen süreçte emekli olan
değerli büyüklerimize plaketleri gala yemeğinde düzenlenecek tören ile takdim edilecektir.
Kongremizin gerçekleştirilmesinde desteklerini esirgemeyen sponsorlarımıza, verdiği maddi
destekten dolayı TÜBİTAK-BİDEB-2223-B Yurtiçi Bilimsel Etkinlik Düzenleme Desteği Programına,
bilimsel kurulda görev alan değerli öğretim üyelerimize, THED 14. Dönem Yeterlik Yürütme Kurulu
ve Alt Komisyonlarında ve diğer Kurullarda görev alan tüm değerli meslektaşlarımıza ve değerli Ea
Organizasyon ve çalışanlarına sonsuz teşekkürü bir borç biliriz.
Son olarak, THED 14. Dönem Yönetim Kurulu Üyelerinin, 14. Ulusal Histoloji ve Embriyoloji
Kongresinin de Düzenleme Kurulunu oluşturduklarını hatırlatarak, kongremizin düzenlenmesinde
verdikleri emekten ve gösterdikleri üstün gayretten dolayı hepsine ayrı ayrı teşekkür ederiz.
Siz değerli üyelerimizin verimli, güzel ve başarılı bir kongre geçirmenizi ve THED ailesi olarak
kuruluşumuzun 28. yılında bu özel anları paylaşabilmek ve ölümsüzleştirebilmek için Antalya’da
buluşabilmeyi dileriz.
Saygılarımızla,
Prof. Dr. A. Çevik TUFAN Prof. Dr. Çiler ÇELİK ÖZENCİ
Kongre Başkanı Kongre Genel Sekreteri
1
14. Ulusal Histoloji ve Embriyoloji Kongresi 10-13 Mayıs 2018, Antalya - Türkiye
KURULLAR

Kongre Düzenleme Kurulu
Türk Histoloji ve Embriyoloji Derneği
Prof. Dr. A. Çevik Tufan
Prof. Dr. Özhan Eyigör
Doç. Dr. Ayten Türkkanı
Doç. Dr. Alev Gürol Bayraktaroğlu
Prof. Dr. Petek Korkusuz
Prof. Dr. Çiğdem Elmas
Prof. Dr. Gülperi Öktem
Prof. Dr. Çiler Çelik Özenci
Prof. Dr. Özgür Çınar

Bilimsel Kurul
Prof. Dr. Gülçin Abban Mete Prof. Dr. Birkan Yakan
Prof. Dr. Serap Arbak Prof. Dr. Melda Yardımoğlu Yılmaz
Prof. Dr. Pergin Atilla Doç. Dr. Serap Cilaker Mıcılı
Prof. Dr. Sevil Çaylı Doç. Dr. Leyla Satı
Prof. Dr. Feriha Ercan Doç. Dr. Gamze Tanrıöver
Prof. Dr. Esra Erdemli Doç. Dr. Şehime Gülsün Temel
Prof. Dr. Hatice Erdost Doç. Dr. Elgin Türköz Uluer
Prof. Dr. Ülker Eren Doç. Dr. Serap Uslu
Prof. Dr. Semiha Ersoy Doç. Dr. Yusufhan Yazır
Prof. Dr. Alpaslan Gökçimen Yrd. Doç. Dr. Neşe Çölçimen
Prof. Dr. Aysel Güven Bağla Yrd. Doç. Dr. Hakan Darıcı
Prof. Dr. Sevinç İnan Yrd. Doç. Dr. Züleyha Erişgin
Prof. Dr. Zeynep Kahveci Yrd. Doç. Dr. Elif Gelenli Dolanbay
Prof. Dr. Narin Liman Yrd. Doç. Dr. Nazlı Ece Ordueri
Prof. Dr. Sevda Müftüoğlu Yrd. Doç. Dr. Aslı Taşlıdere
Prof. Dr. Yusuf Nergiz Yrd.Doç.Dr. Işıl Aydemir
Prof. Dr. Nesrin Özfiliz Yrd.Doç.Dr. Başak Büyük
Prof. Dr. Meltem Özgüner Yrd.Doç.Dr. Alev Cumbul
Prof. Dr. Sait Polat Yrd.Doç.Dr. Seda Karabulut
Prof. Dr. Yavuz Tekelioğlu Yrd.Doç.Dr. İlknur Keskin
Prof. Dr. Murat Tosun Yrd.Doç.Dr. Hilal Nakkaş
Prof. Dr. Yiğit Uyanıkgil Yrd.Doç.Dr. Mehmet Emin Önger
Prof. Dr. Ayşegül Uysal Yrd.Doç.Dr. Fatma Bahar Sunay
Prof. Dr. H. Seda Vatansever

2