CATALOG iifount Harvard School of Public Healt Advancing the Public's Health Through Learning, Discovery, and Communication * i> * r -r m ' Harvard School of Public Health - Departments and Degree Programs, 2002-03 Definition ofTerms Department ofBiostatistics DepartmentofHealth Degrees Policyand Management Biostatistics DPH Doctor ofpublic health SMI, SM2, SD Health care management SMI MOH Masterofoccupational Health decision sciences health SM2, SD Health policy and management SMI, SM2, SD MPH Master ofpublic health Health policy PhD Doctorofphilosophy Department ofCancer Cell PhD (through university Biology SD Doctor ofscience SD program) SM Master ofscience PhD (through the Division of 1 Department ofImmunology (40-credit program) Biological Sciences) nd Infectious Diseases SM2 Master ofscience SD (80-credit program) DepartmentofEnvironmental PhD (through the Division of Health Biological Sciences) MasterofPublic Health Diplomas forthe MPH,DPH,and Environmental epidemiology Program MOH degrees show the degree SMI, SM2, SD Clinical effectiveness only.Diplomas forthe SM and Environmental science and Family and community health SD degrees also showthe name engineering Health care management ofthe department. SMI, SM2, SD International health All PhD programs are offered Occupational health MOH, SMI, SM2, Law and public health underthe aegis ofHarvard SD, DPH Occupational and environmental University's Graduate School of health Arts and Sciences. Physiology SD Quantitative methods Concentrations PhD (through the Division of MPH Department ofMaternal and The names ofthe departments Biological Sciences) Child Health generally conveytheir educa- Population genetics SMI, SM2, SD, DPH tional and research specializa- SD tion,orconcentration. Where Department ofNutrition several concentrations are avail- Department of Epidemiology Nutritional epidemiology able within a department,these SMI, SM2, SD, DPH Public health nutrition are listed in the chart at right.In DPH SD, the Department ofEnviron- PhD (through the Division of mental Health only,the concen- Department of Health and Biological Sciences) trations are shown on diplomas. Social Behavior Areas ofinterest,described in SMI, SM2, SD this catalog but not listed at and Internal right,are generally less formal International health programs than concentrations epidemiology and ecology or are subspecializations within DPH SD, them. International health policy Division of Biological Sciences and economics SD, DPH Cancer cell biology Population and international Environmental health physiology health SM2 Immunology and infectious Population and reproductive diseases health Nutrition DPH SD, PhD 1 Contents Harvard School of Public Health Academic Calendar,2002-03 LETTER FROMTHE DEAN July 1 Registration for summer programs July 2 Summer Program in Clinical Effectiveness and INTRODUCTIONTOTHE HARVARD SCHOOL SummerSession for Public Health Studies OF PUBLIC HEALTH begin July 2-26 Summer 1 term inclusive ACADEMIC DEPARTMENTS July4 Independence Day,a holiday Biostatistics July29-August 16 Summer 2term inclusive CancerCell Biology August 19-30 English for Professional Communication Environmental Health Program Epidemiology September 2 Labor Day,a holiday Health and Social Behavior Health Policyand Management September 3 Fall semester registration for new students September3-6 New-student orientation Immunologyand Infectious Diseases Maternal and Child Health September6 Fall semester registration for returning students Nutrition Population and International Health September 9 Fall 1 term begins October 14 Columbus Day,a holiday INTERDISCIPLINARY PROGRAMS October25 Fall 1 term ends MasterofPublic Health Program October28 Fall 2 term begins Division ofBiological Sciences November 1 Veterans Day,a holiday Division ofPublic Health Practice November28-December 1 Thanksgiving recess Interdisciplinary Concentration in Molecular December 15 Final deadlineforapplication toall doctorof Epidemiology science (SD) and masterofscience (SM) pro- grams;deadlineforapplication to masterof InterdisciplinaryConcentration in the public health (MPH) and masterofoccupa- EpidemiologyofInfectious Disease tional health (MOH) programs in the priority InterdisciplinaryConcentration in Women, admission cycle. Gender,and Health December 16 Final deadlineforapplication toall doctorof Research Centers philosophy (PhD) programs December 20 Fall 2 term ends ACADEMIC SUMMER PROGRAMS December 21-January 1 Winter recess Summer Program in Clinical Effectiveness January2 WinterSession* begins Summer Session for Public Health Studies January20 Martin Luther King,Jr.,Day,a holiday January28 WinterSession ends DEGREE PROGRAMS,ADMISSION,AND February 3 Spring 1 term begins ENROLLMENT February 17 Presidents'Day,a holiday Schoolwide Degree Requirements March 21 Spring 1 term ends Admission to Degree Programs March 22-30 Spring recess Admission to Nondegree Status March 31 Spring 2 term begins Financial Aid May 23 Spring 2 term ends Registration May26 Memorial Day,a holiday June 5 Commencement STUDENT LIFE Boston,Massachusetts *WinterSession is a special academicterm at HSPH offering opportunities Harvard University forcreativityand innovation in learning and teaching.Credit and noncredit Resources and Servicesfor HSPH Students courses and activitiesforWinterSession,as well as relevant school and departmental policies,are listed atthefollowingWeb site: http://www.hsph.harvard.edu/registrar/WinterSession/index.shtml FACULTY INDEX Dean Fro e he twentieth century has witnessed the greatest gains in . quality and duration of life. Most of the gains achieved jr to antibiotics and vaccines are truly attributable to public lth. In the United States, for example, life expectancy has n extended from an average of 47 years in 1900 to almost 80 years in 2002. Yet there are major disparities in life expectancy and harsh inequities in individuals' ability to get ft! — access to the care they need both in different parts of the !• world and within this wealthy country. Some infectious diseases have been vanquished, but new ones such as AIDS emerge or reemerge in drug-resistant strains. Violence, injuries, the great parasitic diseases that kill and handicap millions, environmen- tal and occupational hazards, and health management and financing issues are just some of the challenges within the purview and mandate of public health. The improvement of the health of the nation's and the world's populations demands diverse professional skills combined with the integration of varied disciplines. The courses, departments, centers, programs, and facilities described here in the catalog of the Harvard School of Public Health reflect the scope of the contem- porary public health enterprise. The interests and expertise of faculty at the school are similarly broad, extending across the biological, social, and numeric sciences. There are programs and projects ranging from the molecular biology of AIDS vaccines to the epidemiology of cancer; from women's and children's health to quality-of-care measurement; from risk assessment to international health and human rights. All of these programs are approached with a true sense of dedica- tion on the part of the faculty, students, and staff and with a mutual respect for different ways of contributing to our shared purpose. Our overarching mission is to advance the public's health through learning, dis- covery, and communication. Our objectives are to provide the highest level of education for public health scientists, practitioners, and leaders; to foster new discoveries leading to the improved health of the people of this country and all nations; to strengthen health capacities and services for communities; and to inform policy debate, disseminate health information, and increase awareness of public health as a public good and a fundamental right. We are engaged in an enterprise of vital importance to every individual and to •society. We welcome those who wish to help us meet these challenges and share the satisfying work of changing the world of health and improving the health of the world. Barry R. Bloom Dean The Harvard School of Public Health The Harvard School of Public Health (HSPH) is a direct descendant of the first profes- sional training program in public health in America, the Harvard-MIT School for Health Officers, a joint venture that began in 1913. In 1922 Harvard split off from MIT, and the Harvard School of Public Health was formally established. In 1946 the school celebrated its new sta- tus as a freestanding faculty of Harvard University, no longer an administrative part of the medical school. Since its founding, the school, through its faculty and graduates, has been at the forefront of efforts to stem disease and promote health worldwide. During the early years the focus was on infectious diseases, deadly workplace exposures, — and sanitation from Alice Hamilton's pioneering studies of lead and mercury poisoning, to Thomas Weller's path- breaking research on the polio virus and Philip Drinker's invention of the iron lung. More recently the school has expanded its reach to new areas, includ- ing the effects of race, gender, class, and social isolation on health; the reform of national health systems; and cutting-edge research on the biomarkers of disease. Three Nobel Prizes, a Lasker Prize, two MacArthur Awards, presidential cita- tions, and countless other honors attest to the excellence and impact of this work. Five successive HSPH alumni led the U.S. Centers for Disease Control and Prevention (1962-1989) for an unprece- dented 27 years. More difficult to quan- — — tify but a far better gauge are the per- ceptible gains in length and quality of life that have been realized through all these efforts. Today the faculty of the Harvard School of Public Health includes almost 350 members from the diverse fields and dis- ciplines that constitute public health. The student body comprises over 900 individ- uals from throughout the United States and five dozen other countries. Students, like faculty, come from an array of fields, and include physicians (30 percent of the one third in master of science programs, disciplinary divisions (Biological Sciences student body), health services adminis- and one third in doctoral (doctor of sci- and Public Health Practice); the Office MPH trators, epidemiologists, nurses, dentists, ence, doctor of public health, or doctor for Professional Education (for the lawyers, statisticians, environmental sci- of philosophy) programs. program); and thirteen specialized entists, engineers, research assistants, research centers. The school's academic The school is organized into ten academ- psychologists, and social workers. programs are described in detail here in ic departments, the locus of most teach- Approximately one third of HSPH stu- ing and researching activity; two inter- the catalog. dents are enrolled in the interdisciplinary master of public health (MPH) program, HARVARD SCHOOL OF PUBLIC HEALTH Department of Biostatistics Biostatistics involves the theory and application of statistical science to analyze public health problems and to further biomedical research. The faculty includes leaders in the research laboratories, federal govern- a level of proficiency after one year of development of statistical meth- ment centers, pharmaceutical companies, study comparable to that attained in the ods for clinical trials and obser- and research institutes. 80-credit program. As courses must be vational studies, studies on the environ- Applicants to the department should taken out of sequence to complete the ment, and genomics/genetics. The depart- have successfully completed calculus program in one year, considerable back- ment's research in statistical methods and through multivariable integration and at ground in probability and statistical interdisciplinary collaborations provide least one semester of linear algebra and inference is needed. many opportunities for student participa- have knowledge of a programming lan- The requirements for this degree are tion. guage such as FORTRAN or C. In addi- essentially the same as for the 80-credit Current departmental research on statis- tion, applicants are strongly encouraged program. The 25-credit core must be tical and computing methods for obser- to have completed courses in probability, completed, although students who have vational studies and clinical trials statistics, advanced calculus, and numeri- taken equivalent course work elsewhere includes survival analysis, missing-data cal analysis. Practical knowledge of a sta- may petition to substitute more advanced problems, and causal inference. Other tistical computing package such as SAS, courses. More flexibility is allowed in areas of investigation are environmental SPSS, S-PLUS, or Stata is also desirable. other requirements since only 40 total research (methods for longitudinal stud- credits are required. Other courses are Funding is available to qualified students ies, analyses with incomplete data, and pursuing the doctoral degree. Most of selected in consultation with a faculty meta-analysis); statistical aspects of the the funding is through five biostatistics adviser. study of AIDS and cancer; quantitative training grants in AIDS, cancer, the envi- Health Decision Sciences The concen- problems in health-risk analysis, technol- ronment, mental health, and public tration in health decision sciences offers ogy assessment, and clinical decision health training for underrepresented integrated educational training in deci- making; statistical methodology in psy- minorities. These traineeships require sion sciences within the context of health chiatric research and in genetic studies; U.S. citizenship or permanent residency. problems. This program, which draws on Bayesian statistics; statistical computing; Other limited funding is awarded on a courses offered by the Departments of statistical genetics and computational competitive basis to qualified applicants. Biostatistics and Health Policy and Man- biology; and collaborative research activ- agement, requires 80 credits. A 40-credit ities with biomedical scientists in other cMraesdtietraonfdS4c0i-ecnrceediitn pBiroosgtraatimsst)ics (80- program is not offered. Harvard-affiliated institutions. Biostatistics The main purpose ofthe Of the 80 credits necessary to earn the Degree Programs in Biostatistics 80-credit and 40-credit SM programs with SM, 2.5 credits must be used to fulfill the schoolwide epidemiology requirement, As described below, the department offers a concentration in biostatistics is to pre- and students must complete core courses both 80-credit and 40-credit master of sci- pare students for doctoral study, although ence (SM) programs and a doctor ofsci- a limited number of qualified students in decision analysis for health and med- ence (SD) program with a concentration may pursue the master's degree only. ical practices or for clinical research, SM methods, theory, management science, in biostatistics, as well as an 80-credit For the 80-credit program 2.5 credits program and an SD program with a con- must be used to fulfill the schoolwide ptirsotbiacabliliintfyertehneceo,ryaannddcoapmppluitciantgio;nsa, sta- centration in health decision sciences. epidemiology requirement, and 25 cred- research seminar; and a practicum. Ten Detailed information about requirements ahnadndebleocotkivediospttriiobuntsecdabnybtehefoduenpdaritnmeant. pitrsobmaubsitlibteyetahrenoerdy ianndcoarpeplciocuartsieosnso,nsta- athdedihteiaolntahldcerceidistisonmuscsitenbceeseacronreedafnrdom A master ofpublic health program in tsiisotnicaalndinafnearleynscies, mofetvhaordiasn,cea.ndAnreagrdedsi-- mexetnetndmeadycboree.meTthebycoonbstualitniinnggrperqaucitriec-al quantitative methods and a doctoral pro- tional 15 credits must be chosen from gram in molecular epidemiology are biostatistics courses, of which 10 credits mexepmebreire.ncSetuudnednetrstahlesotuctheolaogseeoffraomfaaculty described in the interdisciplinary section must be selected from a specific list of variety of elective courses. ofthis catalog. For information about biostatistics, health policy and manage- schoolwide requirements for master's and ment, and interdisciplinary offerings. In Doctor of Science in Biostatistics doctoral degrees, see page 59. addition to formal course work, students Biostatistics The doctoral concentration The programs offered by the Department acquire experience in the planning of in biostatistics is designed for those who of Biostatistics provide rigorous training experiments and the analysis of data by have demonstrated both interest and in the development of methodology, col- participating in a consulting seminar. ability in scholarly research. Qualified laboration, teaching, and consultation Students also choose from a variety of applicants may apply to the doctoral on a broad spectrum of health-related elective courses. program without a prior advanced problems. The department prepares stu- The 40-credit program is designed for degree. dents for academic and private-sector students who have a master's degree in Beyond the schoolwide requirement of research careers in the fields of biostatis- one of the mathematical sciences or a introductory epidemiology, the course tics and health decision sciences. Recent doctorate in a quantitative field. Appli- work for the program is built on a 30- graduates have assumed faculty posts at cants must have a mathematical and sta- credit core curriculum similar to that for universities, as well as positions in tistical background sufficient to achieve the master's degree (see above). In addi- DEPARTMENT OF BIOSTATISTICS COURSES OF INSTRUCTION torofstudentadmissionsand advising,Depart- Please notethatthecourses listed aresubjecttochangeand someareoffered inalternateyears. mentofBiostatistics,655 Huntington Avenue, Completecoursedescriptionsareavailableat http://www.hsph.harvard.edu/registrar/courses. Boston,MA02115. Phone:617-432-1056 Introduction toSAS NonparametricMethods Fax:617-739-1781 PrinciplesofBiostatistics—Introductory,I,andII AnalysisofFailureTimeData E-mail:[email protected],edu IntroductiontoStatisticalMethods AnalysisofMultivariateandLongitudinalData Web:http://www.biostat.harvard.edu StatisticsforMedicalResearch-Introductory,II, DesignofScientificInvestigations Formore information about research andtraining Advanced,andTranslational AdvancedStatisticalComputing in health decision sciences,pleasecontactMilton AnalysisofRatesandProportions BayesianMethodologyinBiostatistics C.Weinstein,PhD,DepartmentofHealth Policy and Management,718 Huntington Avenue, RegressionandAnalysisofVarianceinExperimental StatisticalProblemsinDrugDevelopment Boston,MA02115. Research ComputationalMethodsforCategoricalData Phone:617-432-0805 SurveyResearchMethodsinCommunityHealth Analysis E-mail:[email protected] AppliedRegressionforClinicalResearch StatisticalMethodsinHumanGenetics Forinformation on postdoctoral fellowships, PrinciplesofClinicalTrials StatisticalScienceOutreach pleasecontactthechairofthe Postdoctoral Com- BasicsofStatisticalInference StatisticalComputingEnvironments mittee,DepartmentofBiostatistics,655 Hunting- AppliedSurvivalAnalysisandDiscreteDataAnalysis AppliedStochasticProcessesandModelsinPub- ton Avenue,Boston,MA02115. Phone:617-432-1056 SurvivalMethodsinClinicalResearch licHealth Fax:617-739-1781 AppliedLongitudinalAnalysis OperationalMathematics E-mail:[email protected] FundamentalConceptsinGeneMapping ComputationalBiology StatisticalGeneticsinComplexHumanDisease SmoothinginBiostatisticalModeling ProbabilityTheoryandApplicationsIandII DecisionAnalysisforHealthandMedicalPractices DEPARTMENTFACULTY StatisticalInferenceIandII MethodsforDecisionAnalysisinPublicHealth Pleasenotethatsomefacultymembersmaybeon MethodsIandII andMedicine leaveduringacademicyear2002-03. ResearchSynthesisandMeta-AnalysisApplications Cost-EffectivenessandCost-BenefitAnalysisfor Departmentchair:StephenW.Lagakos,MPhil,PhD; inPublicHealthandClinicalMedicine HealthProgramEvaluation HenryPickeringWalcottProfessorofBiostatistics. RegressionandAnalysisofVariance SpatialStatisticsforHealthResearch Statistical methodsin AIDS research;clinicaltrials. SampleSurveys IndependentStudy,FieldExperience RebeccaA.Betensky, PhD;AssociateProfessorof Biostatistics.Sequentialanalysis;correlated binary data. MarcoBonetti, MS,PhD;AssistantProfessorofBiosta- tion, 25 credits of biostatistics courses policy and management is acceptable for tistics.Clinicaltrialandgrowth data;stochasticgeom- are required; these courses are chosen the other minor, provided the courses etryandapplicationstodiseasespatialclustering. by the student in consultation with an focus on subject-oriented rather than PaulJ.Catalano,SD;Lectureron Biostatistics.Repeat- adviser. Students must also complete two quantitative material. ed measures;multivariatemodels;dose-response minors (10 credits each), only one of The course work includes the schoolwide modeling;riskassessment;environmental statistics. which may be quantitative (such as theo- BrentA.Coull,MS,PhD;AssistantProfessorofBiosta- requirement of introductory epidemiolo- tistics.Categoricaldataanalysis;generalized linear retical statistics, health decision sciences, gy; probability theory and applications; mixed models;generalizedadditivemodels. or epidemiologic methods), whereas the statistical theory; 30 credits from the VictorG.DeGruttola,SM,SM,SD;ProfessorofBiosta- other must be substantive (such as the health decision sciences core; and 10 tistics.Methodsforanalysisofrepeated measures biology of cancer or AIDS). credits from the extended core. The last from longitudinalstudies. Doctoral students are required to partici- includes courses in economic analysis, GregoryDiRienzo, MS,PhD;AssistantProfessorof pate as a teaching assistant in a course decision analysis for health and medical Biostatistics.Statistical methodsarising inAIDS offered by the department and to take a practices or for clinical research, meth- research;clinicaltrials. consulting seminar. ods, cost-effectiveness and cost-benefit GarrettFitzmaurice,MSc,MA,SD;AssociateProfessor analysis, decision theory, management, ofBiostatistics.Likelihoodand nonlikelihood Health Decision Sciences The doctoral and analytical methods; a research semi- approachestoanalyzing multivariatebinaryout- concentration in health decision sciences comes. nar; and a practicum. offers integrated educational training in RobertC.Gentleman,MSc,PhD;Associate Professor decision analysis, cost-benefit and cost- All doctoral students are required to ofBiostatistics.Statisticalcomputingandtheanalysis effectiveness analysis, behavioral deci- participate as a teaching assistant in a ofcensoreddata. sion theory, operations research, applied course offered by the department. Stu- RobertJ.Gray,SM,PhD;SeniorLectureron Biostatis- welfare economics, statistical infer—ence, dents must also take a consulting semi- tics.Clinicaltrials;survivalanalysis;techniquesfor computer science, and biostatistics all nar or complete an outside project exploratorydataanalysisand model building. within the context of health problems. approved by the seminar director. DavidP.Harrington,AM,PhD;ProfessorofBiostatis- This program is coordinated with but RELATED OFFERINGS tics.Nonparametricmethodsforcensoreddata; distinct from the decision sciences con- sequentialdesignsforclinicaltrials. centration in the universitywide PhD Interdisciplinaryconcentration in molecularepi- ChengchengHu,MA,MS,PhD;AssistantProfessorof Program in Health Policy, described in demiology,see page57. Biostatistics.Failure-timedata;measurementerror; the Department of Health Policy and MPH concentration in quantitative methods,see missingdata;longitudinaldata;clinicaltrials. Management. page55. WenzhengHuang,ME,PhD;AssistantProfessorof PhD Program in Health Policy,see page33. Biostatistics.Generalized linearmodelsandsurvival The program requires 45 credits of analysis. course work in the major field, plus 10 CONTACT INFORMATION MichaelD.Hughes,MSc,PhD;ProfessorofBiostatis- credits in each of two minor fields, one Formore information about research andtraining tics.Statistical methodsinthedesign,analysis,and of which must be biostatistics. Health in biostatistics,pleasecontact DavidWypij, direc- reportingofclinicaltrialsandoverviews. HARVARD SCHOOL OF PUBLIC HEALTH 2002-03 JosephG.Ibrahim,MS,PhD;AssociateProfessorof Biostatistics.Generalized linearmodels;Bayesian ERICTCHETGEN inferences. HongyuJiang,PhD;AssistantProfessorofBiostatis- Doctoral stude tics.Methodologyforclinicaltrailsandepidemiologic studies;multivariatesurvivalanalysis;bioinformatics. WorldcitizenEricTchetgenwasborninCameroon, KarenM.Kuntz, SM,SD;AssociateProfessorofHealth Decision Science.Cost-effectivenessanalysisof spenthisteenageyearsinFrance,andmovedtothe cancer-screeningstrategies. V UnitedStatestoenrollincollegewhenhewas 19. NanM.Laird,PhD;ProfessorofBiostatistics.Longitu- Midwaythroughhiselectricalengineeringprogramat dinalstudies;nonresponseand missing-data meth- hetooktwoyearsofftotravel,work,andspend ods;discretedataanalysis;Bayesian methods. imewithhisfamily. ChengLi, PhD;AssistantProfessorofBiostatistics. Computational biology;geneticnetworkmodeling. taringthistimehejoinedanagriculturalprojectin YiLi,MS,MS,PhD;AssistantProfessorofBiostatistics. hana,exploringsocialandeconomicincentivestofarmersforadoptingnewhybridvari- Survivalanalysis;longitudinalandspatialdataanalysis. DonnaS.Neuberg,MA,MA,SD;Lectureron Biostatis- etiesofmaize.WhileinGhana,Tchetgensays,"Isawproblemsinbasichealthandhealth tics.Cancerclinicaltrials;geneticepidemiology. policythatseemeddisconnectedfromempiricalresearch.SoIstartedreadingabout MarcelloPagano,SM,PhD;ProfessorofStatistical publichealthandhowtointegrateempiricalmethodsintopolicyandthatledmetothe Computing.Statistical computing;clinicaltrials;epi- SummerPrograminBiostatisticsatHSPH." Tchetgenthensawhowhisquantitativeskills demicmodeling. andbackgroundcouldhelpinsolvingrealhealthproblems. JamesM.Robins,MD;Mitchell L.and Robin LaFoley Dong ProfessorofEpidemiology.Analyticmethods TchetgenreturnedtoYaleandfinishedhisbachelor'sdegreewithadoublemajorinelec- fordrawingcausal inferencesfromcomplexobserva- tionaland randomizedstudies. tricalengineeringandappliedmathematics.Thenheenteredthedoctoralprogramin AndreaG.Rotnitzky,MA,PhD;SeniorLectureron biostatistics/'DuringtheonesummerIhadbeenhere,"hesays,"Ihadmadeconnections Biostatistics.Longitudinal dataanalysis;analysisof withfacultymemberswithwhomIwantedtowork." Nowthatheisattheschoolfulltime, repeatedcategoricaldataandclustercorrelateddata. TchetgenciteshisrelationshipswithfacultymembersashighlightsofhisHSPHexperi- LouiseM.Ryan,PhD;ProfessorofBiostatistics. ence.Tchetgen'sresearchinterestsarecausalinferenceandHIV/AIDS-related Rodenttumorigenicityexperiments;teratology experiments;clinicaltrials;goodness-of-fittests;sur- topics. vivalanalysis. Mei-ChiungShih,MS,PhD;AssistantProfessorofBio- statistics.Statisticalgeneticsandgeneticepidemiolo- Ronghui(Lily)Xu,MA,PhD;AssistantProfessorof JunLiu,PhD;ProfessorintheDepartmentofBiosta- gy;nonlinearand nonparametricregression. Biostatistics.Survivalanalysis,particularlyin relation tistics.Genetics;computational biology;missingdata; KennethE.Stanley,MA,PhD;Lectureron Biostatis- to proportional hazardsmodels;goodnessoffit. Bayesian methodology. tics.Estimating mortalityattributabletotobaccoin MarvinZelen,AM,PhD;ProfessorofStatistical Sci- Sharon-LiseT.Normand,MSc,PhD;Associate Profes- thepresenceofincompleteinformation. enceand MemberoftheFacultyofArtsand Sciences. sorintheDepartmentofBiostatistics.Bayesian infer- MarciaA.Testa,MPH,MPhil,PhD;SeniorLectureron Theoryand practiceofclinicaltrials. ence;graphical models;meta-analysis. Biostatistics.Evaluation ofquality-of-lifeindexesin SecondaryAppointments therapeuticclinicaltrials. E.JohnOrav,PhD;AssociateProfessorinthe Depart- (primaryappointmentsatHarvard Medical School or mentofBiostatistics.Statisticalcomputingandsimu- FlorinVaida,PhD;AssistantProfessorofBiostatistics. FacultyofArtsand Sciences) lation;stochastic modeling;bioassay. Markovchain MonteCarlo;likelihood inference;non- parametricmodeling;longitudinaldata. RogerB.Davis,MA;AssociateProfessorinthe BernardA.Rosner,MA,PhD;Professorinthe Depart- MatthewP.Wand,PhD;AssociateProfessorofBiosta- DepartmentofBiostatistics.Design andanalysisof mentofBiostatistics.Analysisofclustered binary tistics.Nonparametriccurveestimation;Markovchain clinicaltrials;recursivepartitioning methods. data;longitudinaldataanalysis. MonteCarlo;computationalstatistics. DianneM.Finkelstein,AM,PhD;AssociateProfessor DavidA.Schoenfeld,AM,PhD;Professorinthe WeiWang,MS,PhD;AssistantProfessorofBiostatis- intheDepartmentofBiostatistics.Carcinogenicity DepartmentofBiostatistics.Statisticsin medical tics.Survivalanalysis;longitudinalandfunctional experiments;survivalanalysis. research;linearmodels;bioassay;survivaltheory. dataanalysis;semiparametricmodeling. KimberleeGauvreau,SM,SD;AssistantProfessorin DavidWypij,ScM,MS,PhD;AssociateProfessorinthe YouGanWang, MS,PhD;AssociateProfessorofBio- theDepartmentofBiostatistics.Biostatistical issues in DepartmentofBiostatistics.Longitudinaldataanaly- statistics.Sequential clinicaland screeningtrials;esti- clinical studiesin pediatriccardiology;institutional sis;repeated measuresandgrowth curve models. matingfunctionsandasymptoticinference. JamesH.Ware,PhD;FrederickMostellerProfessorof variabilityin outcomesaftercongenital heartdisease GraceWyshak,SM,PhD;AssociateProfessorinthe Biostatisticsand DeanforAcademicAffairs.Design surgery. DepartmentsofBiostatisticsand Populationand andanalysisoflongitudinal studies. RichardD.Gelber,SM,PhD;ProfessorintheDepart- International Health.Biostatistical/demographic mentofBiostatistics.Design/analysisofclinicaltrials. methods. Lee-JenWei, PhD;ProfessorofBiostatistics.Design andanalysisofclinicaltrials;repeated measurements RebeccaS.Gelman, PhD;AssociateProfessorinthe Adjunct Faculty analysis;survivalanalysis. DepartmentofBiostatistics.Clinicaltrials;disease CyrusR.Mehta,SM,PhD.Cytel SoftwareCorporation. MiltonC.Weinstein,AM,MPP,PhD;HenryJ.Kaiser screening;survival methods. ProfessorofHealth Policyand Management.Cost- RobertJ.Glynn,MA,PhD,SM,SD;Associate Professor DeJuranRichardson,MS,PhD.LakeForestCollege. effectivenessofhealth practicesandtechnologies. intheDepartmentofBiostatistics.Analysisoflongi- MichaelA.Stoto,PhD.DepartmentofEpidemiology PaigeL.Williams,BSPH,PhD;Lectureron Biostatis- tudinal data;nonresponsein samplesurveys. and Biostatistics,GeorgeWashington University. tics.Cancerriskassessmentandotherareasofenvi- HulinWu,MS,MS,PhD.FrontierScienceandTechnol- ronmentalstatistics. NDiecphaorltamseTn.tLaonfgBei,osMtaSt,isStDi;csA.sSstoactiisattiecaPlrmofeetshsoordoilnotghye ogyResearch Foundation;Statisticaland DataAnaly- WingHungWong, MS,MS,PhD;ProfessorofCom- forhuman and animal brain mapping. sisCenter,AIDSClinicalTrialsGroup. putational Biology.Bayesian computation;high- dimensional molecularbiologyand genetics. Mei-LingTingLee,MS,MA,PhD;AssociateProfessor inthe DepartmentofBiostatistics.Lifetimedata analysis;categoricaldataanalysis. DEPARTMENT OF BIOSTATISTICS Department of Cancer Cell Biology / -: r->...."«