Case Files: Microbiology (Case Files), 2nd edition

398 Pages·2008·1.64 MB·English

by  Eugene C. Toy

Case Files™
Microbiology
Second Edition EUGENE C.TOY,MD
The John S.Dunn,Senior Academic Chief and Program
Director
The Methodist Hospital-Houston
Obstetrics and Gynecology Residency
Houston,Texas
Clerkship Director,Clinical Associate Professor
Department of Obstetrics/Gynecology
University of Texas Medical School at Houston
Houston,Texas
CYNTHIA DEBORD,PHD
Former Instructor and Course Director of Medical
Microbiology
Department of Microbiology and Molecular Genetics
University of Texas Medical School at Houston
Houston,Texas
AUDREY WANGER,PHD
Associate Professor
Department of Pathology
University of Texas Medical School at Houston
Houston,Texas
GILBERT CASTRO,PHD
Professor (Retired)
Department of Integrative Biology and Pharmacology
University of Texas Medical School at Houston
Vice President for Inter-Institutional Relations (Retired)
University of Texas Health Science Center at Houston
Houston,Texas
JAMES D.KETTERING,PHD
Emeritus Professor
Department of Biochemistry and Microbiology
Loma Linda University School of Medicine
Loma Linda,California
DONALD BRISCOE,MD
Program Director
Family Medicine Residency
New York Chicago San Francisco
The Methodist Hospital-Houston
Lisbon London Madrid Mexico City Medical Director Houston Community Health Centers,Inc.
Milan New Delhi San Juan Seoul Denver Harbor Clinic
Singapore Sydney Toronto Houston,Texas
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DOI: 10.1036/0071492585
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DEDICATION
To Phil Robinson, a modern day miracle worker; he came to
St. Joseph in 2006 amidst turmoil and uncertainty, and with
leadership, vision, and commitment, directed us to a bright and
exciting future.
—ECT
To my parents, Darrell and Ruth, for their ongoing support;
to my loving husband, Wes, and children Emily, Elliot, and Evan.
—CD
To my wife, Georgia, and daughters, Theresa and Mitzi, who havealways
been the ultimate motivation for me to do my work, and enjoy it.
—GC
To my patient wife, Betty, and children, Brian, Pamela, and David.
—JK
To Cal, Casey, Peter, Ben, Kristen, Leonard, Eric, and all of their parents.
—DB
Copyright © 2008 by The McGraw-Hill Companies, Inc. Click here for terms of use.
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Phil Robinson
Chief Operating Officer, Hospital Partners of America
Case Files: Microbiologyis dedicated to Phil Robinson, FACHE, MHA, who
serves as Chief Operating Officer of Hospital Partners of America and CEO of
St. Joseph Medical Center, Houston. With a career in healthcare that has
spanned 30 years, Phil Robinson’s wide experience has stretched across the
country and in for-profit hospitals and not-for-profit facilities. A graduate of
Texas A & M University, Phil received his Masters in Health Administration
from Washington University in St. Louis. He remains active with mentoring
and teaching at both universities.
Mr. Robinson has been listed in Modern Healthcare as an “Up and Comer,”
is a graduateof Leadership Houston, and recently received the Distinguished
Alumnus Award from the Washington University Health Administration
Program. He also provides leadership and insight to boards of several nation-
al and local healthcare and civic organizations. He has held executive positions
with The Methodist Hospital System in Houston, the Alton Ochsner Medical
Foundation and Ochsner Foundation Hospital in Louisiana, JFK Medical
Center in Florida, and with HCA.
In April 2006, Phil accepted the role of interim CEO of St. Joseph Medical
Center in Houston, Texas, while serving as the Vice President of Operations for
the Texas Region. Most recently, Phil was promoted to COO for Hospital
Partners of America and oversees the operational activities of the seven HPA
medical centers in the United States. For our hospital, St. Joseph, he literally
resurrected the institution from being money losing to a now dynamic, money
making, strong hospital. We at St. Joseph, from doctors to nurses, from pharma-
cists to technicians, and from patients to their families, are grateful to Phil
Robinson. He is our modern day hero.
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CONTENTS
CONTRIBUTORS ix
ACKNOWLEDGMENTS xi
INTRODUCTION xiii
SECTION I
Applying the Basic Sciences to Clinical Medicine 1
Part 1. Approach to Learning Microbiology 3
Part 2. Approach to Disease 6
Part 3. Approach to Reading 6
SECTION II
Antimicrobial Therapy 11
Part 1. Antibacterial Agents 13
Part 2. Antiviral Agents 16
Part 3. Antifungal Agents 19
Part 4. Antiparasitic Agents 21
SECTION III
Clinical Cases 25
Fifty Case Scenarios 27
viii CONTENTS
SECTION IV
Listing of Cases 359
Listing by Case Number 361
Listing by Disorder (Alphabetical) 362
INDEX 365