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Cardiopulmonary Anatomy Physiology & Essentials for Respiratory Care Fifth Edition To Katherine, Alexander, Destinee, and Ashley The Next Generation Grandpa T Cardiopulmonary Anatomy Physiology & Essentials for Respiratory Care Terry Des Jardins, MEd, RRT Professor Emeritus Director Department of Respiratory Care Parkland College Champaign, Illinois Australia • Brazil • Japan • Korea • Mexico • Singapore • Spain • United Kingdom • United States Cardiopulmonary Anatomy & Physiology: © 2008Delmar Cengage Learning Essentials for Respiratory Care, Fifth ALL RIGHTS RESERVED. 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Printed in the United States of America 3 4 5 6 7 11 10 09 08 CONTENTS List of Tables • xi Foreword • xiii Preface • xv Acknowledgments • xxiii How to Use the Text and Software • xxvi SECTION ONE 1 The Cardiopulmonary System—The Essentials C H A P T E R 1 The Anatomy and Physiology of the Respiratory System 3 The Airways • 7 The Lungs • 46 The Upper Airway • 7 The Mediastinum • 50 The Lower Airways • 23 The Pleural Membranes • 50 The Sites of Gas Exchange • 36 The Thorax • 51 The Pulmonary Vascular System • 39 The Diaphragm • 52 The Lymphatic System • 43 Chapter Summary • 61 Neural Control of the Lungs • 44 Review Questions • 62 C H A P T E R 2 Ventilation 67 Pressure Differences Across Elastic Properties of the Lung and Chest the Lungs • 68 Wall • 76 Role of the Diaphragm in Ventilation • 72 Dynamic Characteristics of the Lungs • 92 Positive Pressure Ventilation • 74 Ventilatory Patterns • 104 v CONTENTS vi How Normal Intrapleural Pressure Overview of Specific Breathing Differences Cause Regional Conditions • 112 Differences in Normal Lung Chapter Summary • 116 Ventilation • 109 Clinical Applications • 119 The Effect of Airway Resistance and Review Questions • 122 Lung Compliance on Ventilatory Clinical Application Questions • 125 Patterns • 110 C H A P T E R 3 The Diffusion of Pulmonary Gases 127 Gas Laws—Review • 128 Perfusion-Limited Gas Flow • 141 The Partial Pressures of Atmospheric Diffusion-Limited Gas Flow • 142 Gases • 130 How Oxygen Can Be Either Perfusion The Ideal Alveolar Gas Equation • 132 Or Diffusion Limited • 145 The Diffusion of Pulmonary Gases • 133 Chapter Summary • 147 Oxygen and Carbon Dioxide Diffusion Clinical Applications • 147 Across the Alveolar-Capillary Review Questions • 150 Membrane • 134 Clinical Application Gas Diffusion • 138 Questions • 152 C H A P T E R 4 Pulmonary Function Measurements 153 Lung Volumes and Capacities • 154 Chapter Summary • 172 Pulmonary Mechanics • 158 Clinical Applications • 173 How the Effects of Dynamic Review Questions • 177 Compression Decrease Expiratory Clinical Application Flow Rates • 168 Questions • 179 C H A P T E R 5 The Anatomy and Physiology of the Circulatory System 181 The Blood • 182 The Distribution of Pulmonary The Heart • 188 Blood Flow • 205 The Pulmonary and Systemic Vascular Chapter Summary • 219 Systems • 195 Clinical Applications • 220 Pressures in the Pulmonary and Systemic Review Questions • 223 Vascular Systems • 200 Clinical Application The Cardiac Cycle and Its Effect on Questions • 225 Blood Pressure • 201 CONTENTS vii C H A P T E R 6 Oxygen Transport 227 Oxygen Transport • 228 Polycythemia • 262 Oxygen Dissociation Curve • 233 Chapter Summary • 263 Oxygen Transport Calculations • 245 Clinical Applications • 263 Hypoxia • 258 Review Questions • 268 Cyanosis • 261 Clinical Application Questions • 270 C H A P T E R 7 Carbon Dioxide Transport and Acid-Base Balance 271 Carbon Dioxide Transport • 272 Chapter Summary • 310 Carbon Dioxide Elimination at Clinical Applications • 312 the Lungs • 275 Review Questions • 315 Carbon Dioxide Dissociation Curve • 276 Clinical Application Questions • 319 Acid-Base Balance and Regulation • 279 The Role of the P /HCO (cid:2)/pH CO2 3 Relationship in Acid-Base Balance •290 C H A P T E R 8 Ventilation-Perfusion Relationships 321 Ventilation-Perfusion Ratio • 321 Review Questions • 334 Chapter Summary • 330 Clinical Application Questions • 335 Clinical Applications • 331 C H A P T E R 9 Control of Ventilation 337 The Respiratory Components of the Reflexes That Influence Medulla Oblongata—The Respiratory Ventilation • 349 Centers • 338 Chapter Summary • 352 The Influence of the Pontine Respiratory Clinical Applications • 352 Centers on the Respiratory Review Questions • 355 Components of the Medulla Clinical Application Questions • 357 Oblongata • 340 Monitoring Systems That Influence the Respiratory Components of the Medulla Oblongata • 342 CONTENTS viii C H A P T E R 1 0 Fetal Development and the Cardiopulmonary System 359 Fetal Lung Development • 360 Clinical Parameters in the Normal Placenta • 362 Newborn • 371 Fetal Circulation • 365 Chapter Summary • 373 Birth • 368 Clinical Applications • 373 Control of Ventilation in the Review Questions • 376 Newborn • 370 Clinical Application Questions • 377 C H A P T E R 1 1 Aging and the Cardiopulmonary System 379 The Effects of Aging on the The Effects of Aging on the Respiratory System • 381 Cardiovascular System • 387 Pulmonary Gas Exchange • 385 Chapter Summary • 391 Arterial Blood Gases • 385 Review Questions • 391 SECTION TWO 395 Advanced Cardiopulmonary Concepts and Related Areas—The Essentials C H A P T E R 1 2 Electrophysiology of the Heart 397 The Five Phases of the Action Chapter Summary • 404 Potential • 399 Review Questions • 405 Properties of the Cardiac Muscle • 400 C H A P T E R 1 3 The Standard 12-ECG System 407 The Standard 12-ECG System • 408 Chapter Summary • 420 Normal ECG Configurations and Their Review Questions • 422 Expected Measurements (Lead II) • 415
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