Cardioprotective Natural Products.Promises and Hopes PDF
Preview Cardioprotective Natural Products.Promises and Hopes
CARDIOPROTECTIVE NATURAL PRODUCTS Promises and Hopes 10740_9789813231153_TP.indd 1 5/10/17 2:25 PM b2530 International Strategic Relations and China’s National Security: World at the Crossroads TTTThhhhiiiissss ppppaaaaggggeeee iiiinnnntttteeeennnnttttiiiioooonnnnaaaallllllllyyyy lllleeeefffftttt bbbbllllaaaannnnkkkk b2530_FM.indd 6 01-Sep-16 11:03:06 AM CARDIOPROTECTIVE NATURAL PRODUCTS Promises and Hopes Editor Goutam Brahmachari Visva-Bharati University, India World Scientific NEW JERSEY • LONDON • SINGAPORE • BEIJING • SHANGHAI • HONG KONG • TAIPEI • CHENNAI • TOKYO 10740_9789813231153_TP.indd 2 5/10/17 2:25 PM Published by World Scientific Publishing Co. Pte. Ltd. 5 Toh Tuck Link, Singapore 596224 USA office: 27 Warren Street, Suite 401-402, Hackensack, NJ 07601 UK office: 57 Shelton Street, Covent Garden, London WC2H 9HE British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library. CARDIOPROTECTIVE NATURAL PRODUCTS Promises and Hopes Copyright © 2018 by World Scientific Publishing Co. Pte. Ltd. All rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system now known or to be invented, without written permission from the publisher. For photocopying of material in this volume, please pay a copying fee through the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to photocopy is not required from the publisher. ISBN 978-981-3231-15-3 Typeset by Stallion Press Email: [email protected] Printed in Singapore Devi - 10740 - Cardioprotective Natural Products.indd 1 04-10-17 2:51:45 PM “9x6” b2989 Cardioprotective Natural Products: Promises and Hopes Dedicated to Professor Kalisankar Mukherjee (Visva-Bharati University, India) b2989_FM.indd 5 05-10-2017 07:45:01 PM b2530 International Strategic Relations and China’s National Security: World at the Crossroads TTTThhhhiiiissss ppppaaaaggggeeee iiiinnnntttteeeennnnttttiiiioooonnnnaaaallllllllyyyy lllleeeefffftttt bbbbllllaaaannnnkkkk b2530_FM.indd 6 01-Sep-16 11:03:06 AM “9x6” b2989 Cardioprotective Natural Products: Promises and Hopes Contents Foreword ix Preface xi Editor Biography xv List of Contributors xix Chapter 1 Cardioprotective Natural Products: Promises and Hopes — An Overview 1 Goutam Brahmachari Chapter 2 Naturally Occurring Matrix Metalloproteinase Inhibitors: A Group of Promising Cardioprotective Agents 9 Tayebeh Anajafi, Abbas Sedigh and Sanku Mallik Chapter 3 Promising Natural Cardioprotective Agents in Drug- and Toxin-Induced Pathophysiology 47 Semantee Bhattacharya and Parames C. Sil Chapter 4 Natural Products against Drug-Induced Cardiotoxicity 121 Meghana Koneru, Nasiruddin Nalban, Bidya Dhar Sahu and Ramakrishna Sistla Chapter 5 Cardioprotective Potential of Medicinal Plants in Attenuating Doxorubicin-Induced Cardiotoxicity 149 Sameer N. Goyal, C.R. Patil, Nimisha Mishra, Rajesh Mohanraj, Shreesh Ojha vii b2989_FM.indd 7 05-10-2017 07:45:01 PM b2989 Cardioprotective Natural Products: Promises and Hopes “9x6” viii Cardioprotective Natural Products Chapter 6 Role of Dietary Supplements in Cardiovascular Diseases 193 Essam Abdel-Sattar, Soheir M. El Zalabani and Manal M. Sabry Chapter 7 Beneficial Role of Antioxidant Molecules with Therapeutic Potential in Cardiac Disease 247 Jyotirmoy Ghosh, Krishnendu Sinha and Parames C. Sil Chapter 8 Small Molecule Phytocompounds as Promoters of LDL-receptor and PCSK9 Inhibition: Potential Role as Non-statin Based Cardio-protective Agents 277 Ajoy Basak, Paul O’Reilly, Bethel Ozed-Williams, and Sarmistha Basak Chapter 9 7,8-Dihydroxy-3-methylisochroman-4-one: A Promising Anti-hypertensive Lead-Molecule from Banana (Musa sapientun L.) Peel 319 Goutam Brahmachari Index 331 b2989_FM.indd 8 05-10-2017 07:45:01 PM “9x6” b2989 Cardioprotective Natural Products: Promises and Hopes Foreword The quest of cardiovascular scientists is the discovery and development of novel drug targets and drug compounds for the treatment of cardiovascular diseases. Cardiovascular disease includes any condition that adversely affects the structure or function of the heart and vasculature; such as, heart failure, coronary heart disease, stroke, high blood pressure, diseases of the arteries and many others. Standard pharmacological treatments of cardio- vascular disease include angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), antiarrhythmic drugs, anticoa- gulants, antiplatelet drugs, aspirin therapy, beta-blocker drugs, calcium channel blockers, thrombolytic therapy, digoxin, diuretics and nitrates. Natural product drug discovery is an important part of this quest to develop new drug compounds for the treatment of cardiovascular diseases. This book on Cardioprotective Natural Products: Promises and Hopes, edited by Professor Goutam Brahmachari, is a relevant and thorough book that uniquely discusses recent research advances in the discovery and development of cardiovascular natural products for the treatment of cardiovascular diseases. Each of the eight technical chapters of this book discusses recent advances of natural products with cardioprotective promise. These advances include naturally occurring matrix metallo- proteinase (MMPs) inhibitors, phytochemicals, antioxidants, dietary supplements and other plant-based medicinal products. Also, examples of promising cardioprotective lead compounds to treat specific types of cardiovascular diseases are discussed. Professor Brahmachari is an accomplished researcher, teacher, mentor and author. His research interests include isolation, structural ix b2989_FM.indd 9 05-10-2017 07:45:01 PM
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