Cardiac Tumor Pathology PDF
Preview Cardiac Tumor Pathology
Current Clinical Pathology Antonio Giordano, MD, PhD SERIES EDITOR Director, Sbarro Institute for Cancer Research and Molecular Medicine and Center for Biotechnology Temple University Philadelphia, PA, USA For further volumes: http://www.springer.com/series/7632 wwwwwwwwwwww Cristina Basso (cid:129) Marialuisa Valente Gaetano Thiene Editors Cardiac Tumor Pathology Editors Cristina Basso Marialuisa Valente Pathological Anatomy Pathological Anatomy Department of Cardiac Department of Cardiac Thoracic and Vascular Sciences Thoracic and Vascular Sciences Padova , Italy Padova , Italy Gaetano Thiene Pathological Anatomy Department of Cardiac Thoracic and Vascular Sciences Padova , Italy ISBN 978-1-62703-142-4 ISBN 978-1-62703-143-1 (eBook) DOI 10.1007/978-1-62703-143-1 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2012950036 © Springer Science+Business Media New York 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, speci fi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on micro fi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied speci fi cally for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a speci fi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is a brand of Springer Springer is part of Springer Science+Business Media (www.springer.com) To the memory of Ivan Mahaim, a visionary in the diagnosis and treatment of cardiac tumors wwwwwwwwwwww Preface Cardiac tumors were once considered a nosographic entity of scanty interest because of their rarity, the intrinsic diagnostic dif fi culty and the therapeutic impossibility. They were mostly fatal or incidental fi ndings at postmortem. Nowadays they have become a topical subject because of the great advances in clinical imaging (echocardiography, magnetic resonance, and computed tomography) and surgical treatment and are a spectacular example of innova- tion in technology for in vivo diagnosis and therapy. The present monograph goes over these advances with clinicopathologic correlations. About 90% of primary cardiac tumors are benign and the sim- ple surgical removal is curative forever. Another proof as cardio-pulmonary bypass with cardiac arrest and open-heart surgery was a revolutionary step forward in cardiovascular medicine. The book covers history, epidemiology, demographics, clinical diagnosis, imaging, surgery, pathology, and basic sciences aspects of both benign and malignant cardiac neoplasms, either primary or secondary. Chemotherapy and radiotherapy of malignant neoplasms is as well as cardiotoxicity are also addressed. The book is directed to all the researchers and physicians involved in the fi eld of cardiac oncology, from cardiologists to cardiac surgeons, from radi- ologists to pathologists. In this regard, it must be said that cardiac surgery opened the era of surgical pathology also in the fi eld of cardiac diseases. As far as cardiac tumors, although tissue characterization with imaging is tempting, histology and immunohistochemistry remain irreplaceable life- saving steps for diagnosis. The presence of an expert cardiovascular patholo- gist is fundamental in the clinical team dealing with cardiac tumors. This is the reason why pathologists should be interested in reading and consulting the book which however, at difference from previous authoritative books and atlas, include robust clinical and imaging information, with several chapters written by clinicians and surgeons, which represent its peculiarity. Padua , Italy Cristina Basso M.D., Ph.D. Marialuisa Valente M.D. Gaetano Thiene M.D. vii wwwwwwwwwwww Acknowledgments The Editors are supported in their research by the Registry of Cardio- cerebro-vascular Pathology, Veneto Region, Venice, Italy. They also acknowledge Mrs. Chiara Carturan and Mr. Marco Pizzigolotto for their editorial and graphical assistance in preparing this book. ix
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